MD3098G2 - Dihydrate of di( -Ophenoxy)-di[N-(2-oxy-1-benzal)-N1- -oxyfuralhydrazine(2-)copper] with properties of inhibitor of the human myeloid leukemia - Google Patents

Dihydrate of di( -Ophenoxy)-di[N-(2-oxy-1-benzal)-N1- -oxyfuralhydrazine(2-)copper] with properties of inhibitor of the human myeloid leukemia

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Publication number
MD3098G2
MD3098G2 MDA20060022A MD20060022A MD3098G2 MD 3098 G2 MD3098 G2 MD 3098G2 MD A20060022 A MDA20060022 A MD A20060022A MD 20060022 A MD20060022 A MD 20060022A MD 3098 G2 MD3098 G2 MD 3098G2
Authority
MD
Moldova
Prior art keywords
myeloid leukemia
human myeloid
oxyfuralhydrazine
ophenoxy
benzal
Prior art date
Application number
MDA20060022A
Other languages
Romanian (ro)
Russian (ru)
Other versions
MD3098F1 (en
Inventor
Аурелиан ГУЛЯ
Дональд ПОЙРИЕР
Рой ДЖЕННИ
Виктор ЦАПКОВ
Original Assignee
Государственный Университет Молд0
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Государственный Университет Молд0 filed Critical Государственный Университет Молд0
Priority to MDA20060022A priority Critical patent/MD3098G2/en
Publication of MD3098F1 publication Critical patent/MD3098F1/en
Publication of MD3098G2 publication Critical patent/MD3098G2/en

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Abstract

The invention relates to chemistry, namely to the synthesis of the coordinative compounds from the class of aroylhydrazonates of the transition metals and may find its application in medicine for prophylaxis and treatment of the human myeloid leukemia.Summary of the invention consists in that as inhibitor of the human myeloid leukemia is proposed dihydrate of di((µ-Ophenoxy)-di[N-(2-oxy-1-benzal)-N1-α-oxyfuralhydrazine(2-)copper] of formula:The result of the invention consists in the synthesis of the compound, extending the spectrum of highly active inhibitors of the human myeloid leukemia.
MDA20060022A 2006-01-03 2006-01-03 Dihydrate of di( -Ophenoxy)-di[N-(2-oxy-1-benzal)-N1- -oxyfuralhydrazine(2-)copper] with properties of inhibitor of the human myeloid leukemia MD3098G2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
MDA20060022A MD3098G2 (en) 2006-01-03 2006-01-03 Dihydrate of di( -Ophenoxy)-di[N-(2-oxy-1-benzal)-N1- -oxyfuralhydrazine(2-)copper] with properties of inhibitor of the human myeloid leukemia

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
MDA20060022A MD3098G2 (en) 2006-01-03 2006-01-03 Dihydrate of di( -Ophenoxy)-di[N-(2-oxy-1-benzal)-N1- -oxyfuralhydrazine(2-)copper] with properties of inhibitor of the human myeloid leukemia

Publications (2)

Publication Number Publication Date
MD3098F1 MD3098F1 (en) 2006-07-31
MD3098G2 true MD3098G2 (en) 2007-02-28

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Application Number Title Priority Date Filing Date
MDA20060022A MD3098G2 (en) 2006-01-03 2006-01-03 Dihydrate of di( -Ophenoxy)-di[N-(2-oxy-1-benzal)-N1- -oxyfuralhydrazine(2-)copper] with properties of inhibitor of the human myeloid leukemia

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MD (1) MD3098G2 (en)

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MD3655G2 (en) * 2007-09-03 2009-02-28 Государственный Университет Молд0 Inhibitor of human myeloid leukemia on base of bis(2-hydroxy-8-phenyl-tricyclo/7.3.1.0.2,7/-tridecane-13-on-thiosemicarbazonato)copper
MD20110040A1 (en) * 2011-05-10 2012-11-30 Государственный Университет Молд0 Inhibitors of human myeloid leukemia based on 2-[2-(pyridine-2-ilmethylidene)hydrazine]-1,3-benzothiazole and 2-[2-(1-pyridine-2-ilethylidene)hydrazine]-1,3-benzothiazole dihydrate
MD4190C1 (en) * 2011-06-16 2013-07-31 Государственный Университет Молд0 Inhibitor of human myeloid leukemia based on {bis[2-(3,5-dibrom-2-hydroxyphenyl)-2-oxoethyl-piperidin-1-carbodithioato(1-)-O,O′]copper}
MD4215C1 (en) * 2012-07-09 2013-11-30 Государственный Университет Молд0 Inhibitor of human myeloid leukemia based on N-(4-(5-(pyridin-2-yl)-4,5-dihydro-1H-pyrazol-3-yl)phenyl)-2-(pyridin-2-ylmethylen)-hydrazinecarbothioamide
MD4327C1 (en) * 2013-10-22 2015-09-30 Институт Химии Академии Наук Молдовы N-(D8,13-Bicyclohomofarnesenoyl)-3-amino-1,2,4-triazole compound and process for cultivation of Nostoc linckia cyanobacterium with its use
MD4326C1 (en) * 2013-10-22 2015-09-30 Институт Химии Академии Наук Молдовы N-(D8,13-Bicyclohomofarnesenoylamino)carbazole compound and process for cultivation of Nostoc linckia cyanobacterium with its use
MD4393C1 (en) * 2015-09-04 2016-08-31 Государственный Университет Молд0 Inhibitor of human myeloid leukemia HL-60 cells based on nitrato-[N′-(1-pyridine-2-ylmethylidene)-morpholine-4-carbothiohydrazido(1-)]copper
MD4407C1 (en) * 2015-04-29 2016-10-31 Государственный Университет Молд0 Inhibitor of human myeloid leukemia HL-60 cells based on bis[N-(prop-2-en-1-yl)-2-(pyridine-2-ylmethylidene)hydrazinecarbothioamide]nickel(II) chloride hydrate

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MD2851F1 (en) * 2004-08-12 2005-09-30 Universitatea De Stat Din Moldova Inhibitor of human myeloid leukemia on base of asymmetric cobalt trichloroacetate dimer

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MD2851F1 (en) * 2004-08-12 2005-09-30 Universitatea De Stat Din Moldova Inhibitor of human myeloid leukemia on base of asymmetric cobalt trichloroacetate dimer

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MD3655G2 (en) * 2007-09-03 2009-02-28 Государственный Университет Молд0 Inhibitor of human myeloid leukemia on base of bis(2-hydroxy-8-phenyl-tricyclo/7.3.1.0.2,7/-tridecane-13-on-thiosemicarbazonato)copper
MD20110040A1 (en) * 2011-05-10 2012-11-30 Государственный Университет Молд0 Inhibitors of human myeloid leukemia based on 2-[2-(pyridine-2-ilmethylidene)hydrazine]-1,3-benzothiazole and 2-[2-(1-pyridine-2-ilethylidene)hydrazine]-1,3-benzothiazole dihydrate
MD4190C1 (en) * 2011-06-16 2013-07-31 Государственный Университет Молд0 Inhibitor of human myeloid leukemia based on {bis[2-(3,5-dibrom-2-hydroxyphenyl)-2-oxoethyl-piperidin-1-carbodithioato(1-)-O,O′]copper}
MD4215C1 (en) * 2012-07-09 2013-11-30 Государственный Университет Молд0 Inhibitor of human myeloid leukemia based on N-(4-(5-(pyridin-2-yl)-4,5-dihydro-1H-pyrazol-3-yl)phenyl)-2-(pyridin-2-ylmethylen)-hydrazinecarbothioamide
MD4327C1 (en) * 2013-10-22 2015-09-30 Институт Химии Академии Наук Молдовы N-(D8,13-Bicyclohomofarnesenoyl)-3-amino-1,2,4-triazole compound and process for cultivation of Nostoc linckia cyanobacterium with its use
MD4326C1 (en) * 2013-10-22 2015-09-30 Институт Химии Академии Наук Молдовы N-(D8,13-Bicyclohomofarnesenoylamino)carbazole compound and process for cultivation of Nostoc linckia cyanobacterium with its use
MD4407C1 (en) * 2015-04-29 2016-10-31 Государственный Университет Молд0 Inhibitor of human myeloid leukemia HL-60 cells based on bis[N-(prop-2-en-1-yl)-2-(pyridine-2-ylmethylidene)hydrazinecarbothioamide]nickel(II) chloride hydrate
MD4393C1 (en) * 2015-09-04 2016-08-31 Государственный Университет Молд0 Inhibitor of human myeloid leukemia HL-60 cells based on nitrato-[N′-(1-pyridine-2-ylmethylidene)-morpholine-4-carbothiohydrazido(1-)]copper

Also Published As

Publication number Publication date
MD3098F1 (en) 2006-07-31

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Legal Events

Date Code Title Description
FG4A Patent for invention issued
KA4A Patent for invention lapsed due to non-payment of fees (with right of restoration)
MM4A Patent for invention definitely lapsed due to non-payment of fees