MD2102G2 - Способ получения тетраозида (25R)-5a-фуростан-3b,22a, 26-триол]-26-O-b-D-глюкопиранозида - Google Patents
Способ получения тетраозида (25R)-5a-фуростан-3b,22a, 26-триол]-26-O-b-D-глюкопиранозида Download PDFInfo
- Publication number
- MD2102G2 MD2102G2 MDA20010329A MD20010329A MD2102G2 MD 2102 G2 MD2102 G2 MD 2102G2 MD A20010329 A MDA20010329 A MD A20010329A MD 20010329 A MD20010329 A MD 20010329A MD 2102 G2 MD2102 G2 MD 2102G2
- Authority
- MD
- Moldova
- Prior art keywords
- obtaining
- furostan
- glycopyranoside
- triol
- chloroform
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 3
- WFDIJRYMOXRFFG-UHFFFAOYSA-N Acetic anhydride Chemical compound CC(=O)OC(C)=O WFDIJRYMOXRFFG-UHFFFAOYSA-N 0.000 abstract 3
- SQGYOTSLMSWVJD-UHFFFAOYSA-N silver(1+) nitrate Chemical compound [Ag+].[O-]N(=O)=O SQGYOTSLMSWVJD-UHFFFAOYSA-N 0.000 abstract 3
- JUJWROOIHBZHMG-UHFFFAOYSA-N Pyridine Chemical compound C1=CC=NC=C1 JUJWROOIHBZHMG-UHFFFAOYSA-N 0.000 abstract 2
- 239000003480 eluent Substances 0.000 abstract 2
- 240000007377 Petunia x hybrida Species 0.000 abstract 1
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 abstract 1
- 230000021736 acetylation Effects 0.000 abstract 1
- 238000006640 acetylation reaction Methods 0.000 abstract 1
- 239000007864 aqueous solution Substances 0.000 abstract 1
- UXTMROKLAAOEQO-UHFFFAOYSA-N chloroform;ethanol Chemical compound CCO.ClC(Cl)Cl UXTMROKLAAOEQO-UHFFFAOYSA-N 0.000 abstract 1
- SIHHLZPXQLFPMC-UHFFFAOYSA-N chloroform;methanol;hydrate Chemical compound O.OC.ClC(Cl)Cl SIHHLZPXQLFPMC-UHFFFAOYSA-N 0.000 abstract 1
- 238000004587 chromatography analysis Methods 0.000 abstract 1
- 238000005238 degreasing Methods 0.000 abstract 1
- 239000012467 final product Substances 0.000 abstract 1
- 238000002955 isolation Methods 0.000 abstract 1
- UMJSCPRVCHMLSP-UHFFFAOYSA-N pyridine Natural products COC1=CC=CN=C1 UMJSCPRVCHMLSP-UHFFFAOYSA-N 0.000 abstract 1
- 238000007127 saponification reaction Methods 0.000 abstract 1
- 239000000741 silica gel Substances 0.000 abstract 1
- 229910002027 silica gel Inorganic materials 0.000 abstract 1
- 238000010898 silica gel chromatography Methods 0.000 abstract 1
- 239000000243 solution Substances 0.000 abstract 1
- 229930002534 steroid glycoside Natural products 0.000 abstract 1
Landscapes
- Steroid Compounds (AREA)
Abstract
Изобретение относится к биоорганической химии, в частности к способу получения тетраозида [(25R)-5aфуростан-3b,22a,26-триол]-26-O-b-D-глюкопиранозида, обладающего гибберeлиновой активностью.Способ включает обезжиривание семян Petunia Hybrida hort., их экстракцию водно-спиртовым раствором, концентрацию экстракта, хроматографирование полученного остатка на колонке с силикагелем, используя в качестве элюента систему хлороформ-метанол-вода в соотношении 60:30:10...65:35:10, ацетилирование фракций стероидных гликозидов уксусным ангидридом в пиридине, хроматографирование полученных производных на колонке с силикагелем, пропитанным 15% водным раствором AgNO3 в системе элюентов в хлороформ-этанол в соотношении 3:1...45:40 и омыление выделенного перацетата с последующим выделением целевого продукта.Ï. ôîðìóëû: 1Ôèã.: 1
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| MDA20010329A MD2102G2 (ru) | 2001-10-01 | 2001-10-01 | Способ получения тетраозида (25R)-5a-фуростан-3b,22a, 26-триол]-26-O-b-D-глюкопиранозида |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| MDA20010329A MD2102G2 (ru) | 2001-10-01 | 2001-10-01 | Способ получения тетраозида (25R)-5a-фуростан-3b,22a, 26-триол]-26-O-b-D-глюкопиранозида |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| MD2102F1 MD2102F1 (en) | 2003-02-28 |
| MD2102G2 true MD2102G2 (ru) | 2003-08-31 |
Family
ID=19739974
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MDA20010329A MD2102G2 (ru) | 2001-10-01 | 2001-10-01 | Способ получения тетраозида (25R)-5a-фуростан-3b,22a, 26-триол]-26-O-b-D-глюкопиранозида |
Country Status (1)
| Country | Link |
|---|---|
| MD (1) | MD2102G2 (ru) |
-
2001
- 2001-10-01 MD MDA20010329A patent/MD2102G2/ru not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| MD2102F1 (en) | 2003-02-28 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| Jia et al. | Major triterpenoid saponins from Saponaria officinalis | |
| Takashi et al. | High resolution preparative column chromatographic system for gangliosides using DEAE-Sephadex and a new porus silica, Iatrobeads | |
| Garcia et al. | Topical antiinflammatory activity of phytosterols isolated from Eryngium foetidum on chronic and acute inflammation models | |
| EP1047496B1 (en) | The preparation of novel gels for the purification of non-polar extractives | |
| Lin et al. | Chromatographic profiles and identification of new phenolic components of Ginkgo biloba leaves and selected products | |
| Jin et al. | High-performance liquid chromatography separation of cis–trans anthocyanin isomers from wild Lycium ruthenicum Murr. employing a mixed-mode reversed-phase/strong anion-exchange stationary phase | |
| Elbandy et al. | Analysis of saponins as bioactive zoochemicals from the marine functional food sea cucumber Bohadschia cousteaui | |
| Nishimura et al. | Triterpenoid saponins from Ilex kudincha | |
| Choi et al. | Studies on the anti-aging action of Korean ginseng | |
| Ribeiro et al. | Optimization and correlation of HPLC-ELSD and HPLC–MS/MS methods for identification and characterization of sophorolipids | |
| WO1999053933A1 (en) | Process for recovery and purification of saponins and sapogenins from quinoa (chenopodium quinoa) | |
| Voirin et al. | Analytical methods for monoterpene glycosides in grape and wine: I. XAD-2 extraction and gas chromatographic—mass spectrometric determination of synthetic glycosides | |
| Hayashi et al. | Field survey of Glycyrrhiza plants in Central Asia (5). Chemical characterization of G. bucharica Collected in Tajikistan | |
| Dearborn et al. | Lipophosphonoglycan of the plasma membrane of A canthamoeba castellanii. Inositol and phytosphingosine content and general structural features. | |
| Nikolaivits et al. | Enzymatic tailoring of oleuropein from Olea europaea leaves and product identification by HRMS/MS spectrometry | |
| Abreu et al. | Phytochemical analysis and antimicrobial evaluation of Detarium microcarpum bark | |
| Truswell et al. | Separation of cholesterol from its companions, cholestanol and Δ7-choleatenol, by thin-layer chromatography | |
| Tian et al. | Screening for limonoid glucosides in Citrus tangerina (Tanaka) Tseng by high-performance liquid chromatography–electrospray ionization mass spectrometry | |
| Díaz et al. | Cytotoxic activities of flavonoid glycoside acetates from Consolida oliveriana | |
| MD2102G2 (ru) | Способ получения тетраозида (25R)-5a-фуростан-3b,22a, 26-триол]-26-O-b-D-глюкопиранозида | |
| Fecka et al. | Optimization of the separation of flavonoid glycosides and rosmarinic acid from Mentha piperita on HPTLC plates | |
| Weniger et al. | Bioactive triterpenoids from Vochysia pacifica interact with cyclic nucleotide phosphodiesterase isozyme PDE4 | |
| Lee et al. | Novel steroidal saponins from Dioscorea esculenta (Togedokoro) | |
| Nielsen et al. | 2-O-(p-Coumaroyl)-L-malate, 2-O-caffeoyl-L-malate and 2-O-feruloyl-L-malate in Raphanus sativus | |
| Heupel et al. | Evidence for differences in sterol biosynthesis and derivatization in sorghum |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| KA4A | Patent for invention lapsed due to non-payment of fees (with right of restoration) | ||
| MM4A | Patent for invention definitely lapsed due to non-payment of fees |