MD2102G2 - Procedeu de obţinere a tetraozidei [(25R)-5a-furostan-3b,22a, 26-triol]-26-O-b-D-glucopiranozidei - Google Patents
Procedeu de obţinere a tetraozidei [(25R)-5a-furostan-3b,22a, 26-triol]-26-O-b-D-glucopiranozidei Download PDFInfo
- Publication number
- MD2102G2 MD2102G2 MDA20010329A MD20010329A MD2102G2 MD 2102 G2 MD2102 G2 MD 2102G2 MD A20010329 A MDA20010329 A MD A20010329A MD 20010329 A MD20010329 A MD 20010329A MD 2102 G2 MD2102 G2 MD 2102G2
- Authority
- MD
- Moldova
- Prior art keywords
- obtaining
- furostan
- glycopyranoside
- triol
- chloroform
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 3
- WFDIJRYMOXRFFG-UHFFFAOYSA-N Acetic anhydride Chemical compound CC(=O)OC(C)=O WFDIJRYMOXRFFG-UHFFFAOYSA-N 0.000 abstract 3
- SQGYOTSLMSWVJD-UHFFFAOYSA-N silver(1+) nitrate Chemical compound [Ag+].[O-]N(=O)=O SQGYOTSLMSWVJD-UHFFFAOYSA-N 0.000 abstract 3
- JUJWROOIHBZHMG-UHFFFAOYSA-N Pyridine Chemical compound C1=CC=NC=C1 JUJWROOIHBZHMG-UHFFFAOYSA-N 0.000 abstract 2
- 239000003480 eluent Substances 0.000 abstract 2
- 240000007377 Petunia x hybrida Species 0.000 abstract 1
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 abstract 1
- 230000021736 acetylation Effects 0.000 abstract 1
- 238000006640 acetylation reaction Methods 0.000 abstract 1
- 239000007864 aqueous solution Substances 0.000 abstract 1
- UXTMROKLAAOEQO-UHFFFAOYSA-N chloroform;ethanol Chemical compound CCO.ClC(Cl)Cl UXTMROKLAAOEQO-UHFFFAOYSA-N 0.000 abstract 1
- SIHHLZPXQLFPMC-UHFFFAOYSA-N chloroform;methanol;hydrate Chemical compound O.OC.ClC(Cl)Cl SIHHLZPXQLFPMC-UHFFFAOYSA-N 0.000 abstract 1
- 238000004587 chromatography analysis Methods 0.000 abstract 1
- 238000005238 degreasing Methods 0.000 abstract 1
- 239000012467 final product Substances 0.000 abstract 1
- 238000002955 isolation Methods 0.000 abstract 1
- UMJSCPRVCHMLSP-UHFFFAOYSA-N pyridine Natural products COC1=CC=CN=C1 UMJSCPRVCHMLSP-UHFFFAOYSA-N 0.000 abstract 1
- 238000007127 saponification reaction Methods 0.000 abstract 1
- 239000000741 silica gel Substances 0.000 abstract 1
- 229910002027 silica gel Inorganic materials 0.000 abstract 1
- 238000010898 silica gel chromatography Methods 0.000 abstract 1
- 239000000243 solution Substances 0.000 abstract 1
- 229930002534 steroid glycoside Natural products 0.000 abstract 1
Landscapes
- Steroid Compounds (AREA)
Abstract
Invenţia se referă la chimia bioorganică, în special la un procedeu de obţinere a tetraozidei [(25R)-5a- furostan-3b,22a,26-triol]-26-O-b-D-glucopiranozidei, ce manifestă activitate giberelinică.Procedeul include degresarea seminţelor de Petunia Hybrida hort., extracţia lor cu soluţie hidroalcoolică, concentrarea extractului, cromatografierea restului obţinut pe coloană cu silicagel, utilizând în calitate de eluent sistemul cloroform-metanol-apă în proporţie de 60:30:10 ...65:35:10, acetilarea fracţiunilor de glicozide steroidice cu anhidridă acetică în piridină, cromatografierea derivaţilor obţinuţi pe coloană cu silicagel impregnat cu soluţie apoasă de 15% AgNO3 în sistemul eluenţilor de cloroform-etanol în proporţie de 3:1...45:40 şi saponificarea peracetatului separat cu izolarea ulterioară a produsului finit.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| MDA20010329A MD2102G2 (ro) | 2001-10-01 | 2001-10-01 | Procedeu de obţinere a tetraozidei [(25R)-5a-furostan-3b,22a, 26-triol]-26-O-b-D-glucopiranozidei |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| MDA20010329A MD2102G2 (ro) | 2001-10-01 | 2001-10-01 | Procedeu de obţinere a tetraozidei [(25R)-5a-furostan-3b,22a, 26-triol]-26-O-b-D-glucopiranozidei |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| MD2102F1 MD2102F1 (ro) | 2003-02-28 |
| MD2102G2 true MD2102G2 (ro) | 2003-08-31 |
Family
ID=19739974
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MDA20010329A MD2102G2 (ro) | 2001-10-01 | 2001-10-01 | Procedeu de obţinere a tetraozidei [(25R)-5a-furostan-3b,22a, 26-triol]-26-O-b-D-glucopiranozidei |
Country Status (1)
| Country | Link |
|---|---|
| MD (1) | MD2102G2 (ro) |
-
2001
- 2001-10-01 MD MDA20010329A patent/MD2102G2/ro not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| MD2102F1 (ro) | 2003-02-28 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| KA4A | Patent for invention lapsed due to non-payment of fees (with right of restoration) | ||
| MM4A | Patent for invention definitely lapsed due to non-payment of fees |