MD20C2 - The method of obtaining Macrolytic compounds - Google Patents

The method of obtaining Macrolytic compounds

Info

Publication number
MD20C2
MD20C2 MD94-0087A MD940087A MD20C2 MD 20 C2 MD20 C2 MD 20C2 MD 940087 A MD940087 A MD 940087A MD 20 C2 MD20 C2 MD 20C2
Authority
MD
Moldova
Prior art keywords
group
macrolytic
done
obtaining
case
Prior art date
Application number
MD94-0087A
Other languages
Romanian (ro)
Russian (ru)
Other versions
MD20B1 (en
Inventor
Derek R. Sutherland
L. Pereira Oswy
Hazel M Noble
Michael V.J RAMSAY
John B. Ward
Richard A Fletton
Edward P. Tiley
Neil Porter
David Noble
Original Assignee
Эмерикэн Сайенэмид Компэни
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Эмерикэн Сайенэмид Компэни filed Critical Эмерикэн Сайенэмид Компэни
Publication of MD20C2 publication Critical patent/MD20C2/en
Publication of MD20B1 publication Critical patent/MD20B1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/22—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains four or more hetero rings
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/90—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having two or more relevant hetero rings, condensed among themselves or with a common carbocyclic ring system
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N49/00—Biocides, pest repellants or attractants, or plant growth regulators, containing compounds containing the group, wherein m+n>=1, both X together may also mean —Y— or a direct carbon-to-carbon bond, and the carbon atoms marked with an asterisk are not part of any ring system other than that which may be formed by the atoms X, the carbon atoms in square brackets being part of any acyclic or cyclic structure, or the group, wherein A means a carbon atom or Y, n>=0, and not more than one of these carbon atoms being a member of the same ring system, e.g. juvenile insect hormones or mimics thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/01—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing oxygen

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Plant Pathology (AREA)
  • Dentistry (AREA)
  • Pest Control & Pesticides (AREA)
  • Agronomy & Crop Science (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Insects & Arthropods (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Saccharide Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Cephalosporin Compounds (AREA)

Abstract

The invention relates to macrolytic substances, particularly to obtaining chemical compounds with general formula:in which R1 is CH3, CH2H5 -or izo -C3H7; R2 is inferior alkyl, the group NOR2 is in configuration. E and OR3 is hydroxyl which is antygelyc and insectycide. The synthesis is done by restablishment of chemical compound of formula I in which instead of group OR3 is cetonic group with the help of one agent which is capable to reduce stereoselectiv cetogroup - 5 -a of hydrid boric of metal alkalyne or hydric litiualkoxil aluminium, in the first case the process was done in the dissolvent medium alkonol at (-30)-(Ş30)°C and in the second case ordinary ether was used at temperature (-78)-0°C/ The new substances have a little toxicity and are active against spiders, cicada of potatoes, the tabacco moths.
MD940087A 1986-06-06 1994-04-27 Process for obtaining macrolide compounds MD20B1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB868613790A GB8613790D0 (en) 1986-06-06 1986-06-06 Chemical compounds
SU874203050A RU1831483C (en) 1986-06-06 1987-06-05 Method of preparing macarlide compounds
SU894613245A SU1731060A3 (en) 1986-06-06 1989-01-13 Method of macrolide compounds synthesis

Publications (2)

Publication Number Publication Date
MD20C2 true MD20C2 (en) 1994-05-31
MD20B1 MD20B1 (en) 1994-05-31

Family

ID=10599054

Family Applications (3)

Application Number Title Priority Date Filing Date
MD940087A MD20B1 (en) 1986-06-06 1994-04-27 Process for obtaining macrolide compounds
MD94-0129A MD123C2 (en) 1986-06-06 1994-05-31 Method of obtaining of macrolidine derivers
MD94-0360A MD1026G2 (en) 1986-06-06 1994-07-14 Macrolide compounds

Family Applications After (2)

Application Number Title Priority Date Filing Date
MD94-0129A MD123C2 (en) 1986-06-06 1994-05-31 Method of obtaining of macrolidine derivers
MD94-0360A MD1026G2 (en) 1986-06-06 1994-07-14 Macrolide compounds

Country Status (10)

Country Link
AP (1) AP38A (en)
GB (1) GB8613790D0 (en)
GE (1) GEP19970660B (en)
LT (3) LT3676B (en)
LV (1) LV5678A3 (en)
MD (3) MD20B1 (en)
RU (1) RU1831483C (en)
SU (1) SU1731060A3 (en)
UA (2) UA18587A (en)
ZA (1) ZA874052B (en)

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2166436A (en) * 1984-09-14 1986-05-08 Glaxo Group Ltd Antibiotic compounds and their preparation

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB216646A (en) 1923-04-17 1924-06-05 Reginald Arthur Angier Improvements in feeding troughs for pigs and other animals
DE3446134A1 (en) * 1984-12-18 1986-06-26 G. Düsterloh GmbH, 4322 Sprockhövel REVERSIBLE HYDRAULIC MACHINE
AU596586B2 (en) * 1985-04-30 1990-05-10 American Cyanamid Company Chemical derivatives of antibiotics S541

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2166436A (en) * 1984-09-14 1986-05-08 Glaxo Group Ltd Antibiotic compounds and their preparation

Also Published As

Publication number Publication date
LTIP1649A (en) 1995-07-25
LV5678A3 (en) 1994-10-20
GEP19970660B (en) 1997-01-04
UA18587A (en) 1997-12-25
LT2643B (en) 1994-04-25
MD940360A (en) 1996-04-30
AP38A (en) 1989-04-13
ZA874052B (en) 1988-02-24
MD123C2 (en) 1995-06-30
AP8700065A0 (en) 1987-05-01
LTIP1076A (en) 1995-04-25
UA12797A (en) 1997-02-28
LT3676B (en) 1996-01-25
SU1731060A3 (en) 1992-04-30
GB8613790D0 (en) 1986-07-09
MD123B1 (en) 1994-12-31
MD1026G2 (en) 1999-06-30
RU1831483C (en) 1993-07-30
MD20B1 (en) 1994-05-31

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Legal Events

Date Code Title Description
FG4A Patent for invention issued
IF99 Valid patent on 19990615

Free format text: EXPIRES: 20070604

MK4A Patent for invention expired