MD20160019A2 - Compuşi noi de indazol şi procedeu de obţinere a acestora - Google Patents

Compuşi noi de indazol şi procedeu de obţinere a acestora

Info

Publication number
MD20160019A2
MD20160019A2 MDA20160019A MD20160019A MD20160019A2 MD 20160019 A2 MD20160019 A2 MD 20160019A2 MD A20160019 A MDA20160019 A MD A20160019A MD 20160019 A MD20160019 A MD 20160019A MD 20160019 A2 MD20160019 A2 MD 20160019A2
Authority
MD
Moldova
Prior art keywords
preparation
indazole compounds
novel indazole
novel
compounds
Prior art date
Application number
MDA20160019A
Other languages
English (en)
Russian (ru)
Inventor
Думабала Сриниваса РЕДДИ
Чайтанья САКСЕНА
Кашинатх КОМИРИШЕТТИ
Original Assignee
Council Of Scientific & Industrial Research
Shantani Proteome Analytics Pvt.Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Council Of Scientific & Industrial Research, Shantani Proteome Analytics Pvt.Ltd filed Critical Council Of Scientific & Industrial Research
Publication of MD20160019A2 publication Critical patent/MD20160019A2/ro

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4184—1,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A61K31/416—1,2-Diazoles condensed with carbocyclic ring systems, e.g. indazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4178—1,3-Diazoles not condensed 1,3-diazoles and containing further heterocyclic rings, e.g. pilocarpine, nitrofurantoin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
    • A61P5/50—Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond

Abstract

Prezenta invenţie se referă la compuşi noi de indazol cu formula generală Işi la analogi ai acestora, la utilizarea acestora pentru tratamentul diabetului zaharat, complicaţiilor diabetice, disfuncţiilor cardiovasculare sau al bolilor asociate, la compoziţii farmaceutice care îi conţin, precum şi la un procedeu de preparare a acestora.
MDA20160019A 2013-07-31 2014-07-31 Compuşi noi de indazol şi procedeu de obţinere a acestora MD20160019A2 (ro)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN2296DE2013 2013-07-31
PCT/IN2014/000507 WO2015015519A1 (en) 2013-07-31 2014-07-31 Novel indazole compounds and a process for the preparation thereof

Publications (1)

Publication Number Publication Date
MD20160019A2 true MD20160019A2 (ro) 2016-06-30

Family

ID=51795688

Family Applications (1)

Application Number Title Priority Date Filing Date
MDA20160019A MD20160019A2 (ro) 2013-07-31 2014-07-31 Compuşi noi de indazol şi procedeu de obţinere a acestora

Country Status (18)

Country Link
US (1) US9737510B2 (ro)
EP (1) EP3027605B1 (ro)
JP (1) JP6474808B2 (ro)
KR (1) KR20160053916A (ro)
CN (1) CN106103427B (ro)
AU (1) AU2014297912A1 (ro)
BR (1) BR112016002176A2 (ro)
CA (1) CA2919953A1 (ro)
DK (1) DK3027605T3 (ro)
EA (1) EA201690240A1 (ro)
ES (1) ES2656475T3 (ro)
MA (1) MA38849B1 (ro)
MD (1) MD20160019A2 (ro)
MX (1) MX2016001331A (ro)
MY (1) MY176807A (ro)
SG (1) SG11201600744UA (ro)
WO (1) WO2015015519A1 (ro)
ZA (1) ZA201601177B (ro)

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS57501378A (ro) 1980-09-05 1982-08-05
PH27357A (en) 1989-09-22 1993-06-21 Fujisawa Pharmaceutical Co Pyrazole derivatives and pharmaceutical compositions comprising the same
AU8748798A (en) * 1997-08-22 1999-03-16 Kyowa Hakko Kogyo Co. Ltd. 4-aminoquinazoline derivatives
WO1999032482A1 (en) * 1997-12-19 1999-07-01 Eli Lilly And Company Hypoglycemic imidazoline compounds
JP2000154139A (ja) * 1998-09-16 2000-06-06 Kyowa Hakko Kogyo Co Ltd 縮環ピラジン誘導体
YU54202A (sh) 2000-01-18 2006-01-16 Agouron Pharmaceuticals Inc. Jedinjenja indazola, farmaceutske smeše i postupci za stimulisanje i inhibiranje ćelijske proliferacije
ATE449763T1 (de) 2001-04-16 2009-12-15 Eisai R&D Man Co Ltd 1h-indazolverbindungen die jnk hemmen
US20030109550A1 (en) 2001-09-19 2003-06-12 Michael Clare Substituted indazole compounds for the treatment of inflammation
US20040009976A1 (en) * 2002-04-30 2004-01-15 Kumiko Takeuchi Hypoglycemic imidazoline compounds
US6878735B2 (en) 2002-05-31 2005-04-12 Board Of Trustees Of Michigan State University Multi-substituted imidazolines and method of use thereof
US20050090529A1 (en) * 2003-07-31 2005-04-28 Pfizer Inc 3,5 Disubstituted indazole compounds with nitrogen-bearing 5-membered heterocycles, pharmaceutical compositions, and methods for mediating or inhibiting cell proliferation
EP1893569A4 (en) * 2005-06-10 2009-08-05 Elixir Pharmaceuticals Inc SULPHONAMIDE COMPOUNDS AND ITS USES
JP2013501792A (ja) 2009-08-10 2013-01-17 サミュメッド リミテッド ライアビリティ カンパニー Ｗｎｔ／ｂ−カテニンシグナル伝達経路阻害剤としてのインダゾールおよびその治療的使用
US7947728B1 (en) 2009-11-11 2011-05-24 Hoffmann-La Roche Inc. Indole and indazole analogs as glycogen synthase activators

Also Published As

Publication number Publication date
WO2015015519A1 (en) 2015-02-05
BR112016002176A2 (pt) 2017-08-01
AU2014297912A1 (en) 2016-02-25
CN106103427B (zh) 2019-07-16
MA38849B1 (fr) 2018-09-28
KR20160053916A (ko) 2016-05-13
EA201690240A1 (ru) 2016-10-31
US9737510B2 (en) 2017-08-22
EP3027605A1 (en) 2016-06-08
JP2016525570A (ja) 2016-08-25
JP6474808B2 (ja) 2019-02-27
MY176807A (en) 2020-08-21
DK3027605T3 (en) 2018-01-22
CN106103427A (zh) 2016-11-09
US20160185759A1 (en) 2016-06-30
CA2919953A1 (en) 2015-02-05
MX2016001331A (es) 2017-02-06
SG11201600744UA (en) 2016-02-26
ZA201601177B (en) 2017-11-29
ES2656475T3 (es) 2018-02-27
MA38849A1 (fr) 2017-12-29
EP3027605B1 (en) 2017-11-08

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Legal Events

Date Code Title Description
FA9A Abandonment or withdrawal of application (patent for invention)