MD1574C2 - Săruri de alchilamoniu ale acidului N,N1-malonil-bis-p-aminobenzoic, procedeu de obţinere şi utilizarea lor în calitate de remediu hipotensiv şi antiaritmic - Google Patents
Săruri de alchilamoniu ale acidului N,N1-malonil-bis-p-aminobenzoic, procedeu de obţinere şi utilizarea lor în calitate de remediu hipotensiv şi antiaritmic Download PDFInfo
- Publication number
- MD1574C2 MD1574C2 MD99-0187A MD990187A MD1574C2 MD 1574 C2 MD1574 C2 MD 1574C2 MD 990187 A MD990187 A MD 990187A MD 1574 C2 MD1574 C2 MD 1574C2
- Authority
- MD
- Moldova
- Prior art keywords
- alkylaminic
- malonyl
- bis
- salts
- aminobenzoic acid
- Prior art date
Links
- 229960004050 aminobenzoic acid Drugs 0.000 title abstract 3
- 150000003839 salts Chemical class 0.000 title abstract 3
- 208000001953 Hypotension Diseases 0.000 abstract 1
- 230000004071 biological effect Effects 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 208000021822 hypotensive Diseases 0.000 abstract 1
- 230000001077 hypotensive effect Effects 0.000 abstract 1
Landscapes
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
Invenţia se referă la domeniul chimiei, în special la derivaţii acidului N,N1-malonil-bis-p-aminobenzoic, care posedă activitate biologică şi poate fi utilizată în medicină.Sunt revendicate sărurile de alchilamoniu ale acidului N,N1-malonil-bis-p-aminobenzoic cu formula generală:CH2[CONHC6H4COO]-2 . 2N+H(R1R2R3),în care R1 este H, CH3;R2 - H, CH3, C2H5, C2H4OH;R3 - C2H5, C2H4OH, C3H6OH, CH(CH3)-(CH2)3-N(C2H5)2,şi de asemenea procedeul de obţinere şi utilizarea acestor compuşi în calitate de remediu hipotensiv şi antiaritmic.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| MD99-0187A MD1574C2 (ro) | 1999-06-04 | 1999-06-04 | Săruri de alchilamoniu ale acidului N,N1-malonil-bis-p-aminobenzoic, procedeu de obţinere şi utilizarea lor în calitate de remediu hipotensiv şi antiaritmic |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| MD99-0187A MD1574C2 (ro) | 1999-06-04 | 1999-06-04 | Săruri de alchilamoniu ale acidului N,N1-malonil-bis-p-aminobenzoic, procedeu de obţinere şi utilizarea lor în calitate de remediu hipotensiv şi antiaritmic |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| MD1574B1 MD1574B1 (ro) | 2000-12-31 |
| MD1574C2 true MD1574C2 (ro) | 2001-06-30 |
Family
ID=19739436
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MD99-0187A MD1574C2 (ro) | 1999-06-04 | 1999-06-04 | Săruri de alchilamoniu ale acidului N,N1-malonil-bis-p-aminobenzoic, procedeu de obţinere şi utilizarea lor în calitate de remediu hipotensiv şi antiaritmic |
Country Status (1)
| Country | Link |
|---|---|
| MD (1) | MD1574C2 (ro) |
-
1999
- 1999-06-04 MD MD99-0187A patent/MD1574C2/ro not_active IP Right Cessation
Non-Patent Citations (4)
| Title |
|---|
| Řĺďĺëü Ф. Г., Дашкевич Л. Б., Казанов А. Д. и др., Синтез и механизм действия физиологически активных веществ, Тезисы докладов Всесоюзной конференции, Одесса, 1976, с. 115-117. * |
| Дашкевич Л. Б., Мельникова Т. А., Соколов К. В. и др., Синтез и фармакологические свойства N,N1-оксалилсукцинил-бис-новокаина и его аналогов, Медицина, Москва, Химико-фармацевтический журнал, 1971, с. 22-24. * |
| Машковский М. Д., Лекарственные средства, Кишинев, Штиинца, 1990, Ч. 2, с. 352,360,371. * |
| Рубцов М. А., Байчиков А. Г., Синтетические химико-фармацевтические препараты, Москва, Медицина, 1971, с.77-81. * |
Also Published As
| Publication number | Publication date |
|---|---|
| MD1574B1 (ro) | 2000-12-31 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| TR200000837A2 (tr) | Anti-kanser bileşimleri hazırlamak için işlem ve ara maddeler. | |
| GEP20033114B (en) | Biphenyl Sulfonamides as Dual Angiotensin Endothelin Receptor Antagonists, Method for Their Production and Pharmaceutical Compositions Containing the Same | |
| PT79819B (en) | Process to prepare dihydropiridazinone derivatives its salts and pharmaceutical compositions and intermediate compounds there with | |
| GR3004902T3 (ro) | ||
| MY123310A (en) | Benzimidazoles, the preparation thereof and their use as pharmaceutical compositions | |
| DK0437030T3 (da) | Anvendelse af 4-substituerede imidazoler til nedsættelse af det intraoculære tryk | |
| HU9301155D0 (en) | Methods for producing steroide derivatives and for their application in medical treatment | |
| MXPA03011954A (es) | Nuevos derivados de acido sulfonico. | |
| HU907025D0 (en) | Process for producing substituted n-(imidazolyl-alkyl)-alanine derivatives and pharmaceutical preparatives containing these compounds as active substance | |
| EP1077218A3 (en) | Peptido-mimetic compounds containing RGD sequence useful as integrin inhibitors | |
| MXPA02006249A (es) | Nuevos derivados de azabiciclooctano, utiles en el tratamiento de arritmias cardiacas. | |
| NZ222015A (en) | 7-(meta-substituted phenylglycine)-1-carba-1-dethiacephalsporins and pharmaceutical compositions | |
| NZ213577A (en) | 1-piperazin-3- phenylindanes and pharmaceutical compositions | |
| ATE62908T1 (de) | Neue derivate von 4,5-dihydro-oxazolen, verfahren zu ihrer herstellung und ihre verwendung. | |
| MD1574C2 (ro) | Săruri de alchilamoniu ale acidului N,N1-malonil-bis-p-aminobenzoic, procedeu de obţinere şi utilizarea lor în calitate de remediu hipotensiv şi antiaritmic | |
| AU7556000A (en) | Urea compounds, process for producing the same and use thereof | |
| PT82650A (en) | Process for preparing spiro-imidazolidines useful as aldose reductable inhibitors | |
| GR3020292T3 (en) | Use of 2-iminothiazolidin-4-one derivatives as new medicaments | |
| IL162058A0 (en) | Hexacyclic compounds | |
| ATE190628T1 (de) | Zusammensetzungen von wachstumsfaktoren, herstellung und verwendung | |
| LV11324A (lv) | Panemiens 3-hidroksi-5-/2-(dimetilamino) etil/-2,3-dihidro-2-(4-metoksifenil)-1,5-benzotiazepin-4(5H)-ona iegusanai un mineta savienojuma pielietojums | |
| EP1057829A4 (en) | Condensed pyrimidine derivatives and pharmaceutical compositions containing them | |
| ZA829526B (en) | (1,2)-fused 1,4-benzodiazepine compounds, process for their preparation and compounds containing them | |
| DE69011748D1 (de) | Biphenyl-Derivate, Verfahren zu deren Herstellung und deren Zwischenprodukte. | |
| HUT40658A (en) | Process for producing benzo/c/-1,5-naphtiridin derivatives and pharmaceutical compositions containing them as active agents |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MM4A | Patent for invention definitely lapsed due to non-payment of fees |