MD1574C2 - Săruri de alchilamoniu ale acidului N,N1-malonil-bis-p-aminobenzoic, procedeu de obţinere şi utilizarea lor în calitate de remediu hipotensiv şi antiaritmic - Google Patents
Săruri de alchilamoniu ale acidului N,N1-malonil-bis-p-aminobenzoic, procedeu de obţinere şi utilizarea lor în calitate de remediu hipotensiv şi antiaritmic Download PDFInfo
- Publication number
- MD1574C2 MD1574C2 MD99-0187A MD990187A MD1574C2 MD 1574 C2 MD1574 C2 MD 1574C2 MD 990187 A MD990187 A MD 990187A MD 1574 C2 MD1574 C2 MD 1574C2
- Authority
- MD
- Moldova
- Prior art keywords
- alkylaminic
- malonyl
- bis
- salts
- aminobenzoic acid
- Prior art date
Links
- 229960004050 aminobenzoic acid Drugs 0.000 title abstract 3
- 150000003839 salts Chemical class 0.000 title abstract 3
- 208000001953 Hypotension Diseases 0.000 abstract 1
- 230000004071 biological effect Effects 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 208000021822 hypotensive Diseases 0.000 abstract 1
- 230000001077 hypotensive effect Effects 0.000 abstract 1
Landscapes
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
Invenţia se referă la domeniul chimiei, în special la derivaţii acidului N,N1-malonil-bis-p-aminobenzoic, care posedă activitate biologică şi poate fi utilizată în medicină.Sunt revendicate sărurile de alchilamoniu ale acidului N,N1-malonil-bis-p-aminobenzoic cu formula generală:CH2[CONHC6H4COO]-2 . 2N+H(R1R2R3),în care R1 este H, CH3;R2 - H, CH3, C2H5, C2H4OH;R3 - C2H5, C2H4OH, C3H6OH, CH(CH3)-(CH2)3-N(C2H5)2,şi de asemenea procedeul de obţinere şi utilizarea acestor compuşi în calitate de remediu hipotensiv şi antiaritmic.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| MD99-0187A MD1574C2 (ro) | 1999-06-04 | 1999-06-04 | Săruri de alchilamoniu ale acidului N,N1-malonil-bis-p-aminobenzoic, procedeu de obţinere şi utilizarea lor în calitate de remediu hipotensiv şi antiaritmic |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| MD99-0187A MD1574C2 (ro) | 1999-06-04 | 1999-06-04 | Săruri de alchilamoniu ale acidului N,N1-malonil-bis-p-aminobenzoic, procedeu de obţinere şi utilizarea lor în calitate de remediu hipotensiv şi antiaritmic |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| MD1574B1 MD1574B1 (ro) | 2000-12-31 |
| MD1574C2 true MD1574C2 (ro) | 2001-06-30 |
Family
ID=19739436
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MD99-0187A MD1574C2 (ro) | 1999-06-04 | 1999-06-04 | Săruri de alchilamoniu ale acidului N,N1-malonil-bis-p-aminobenzoic, procedeu de obţinere şi utilizarea lor în calitate de remediu hipotensiv şi antiaritmic |
Country Status (1)
| Country | Link |
|---|---|
| MD (1) | MD1574C2 (ro) |
-
1999
- 1999-06-04 MD MD99-0187A patent/MD1574C2/ro not_active IP Right Cessation
Non-Patent Citations (4)
| Title |
|---|
| Řĺďĺëü Ф. Г., Дашкевич Л. Б., Казанов А. Д. и др., Синтез и механизм действия физиологически активных веществ, Тезисы докладов Всесоюзной конференции, Одесса, 1976, с. 115-117. * |
| Дашкевич Л. Б., Мельникова Т. А., Соколов К. В. и др., Синтез и фармакологические свойства N,N1-оксалилсукцинил-бис-новокаина и его аналогов, Медицина, Москва, Химико-фармацевтический журнал, 1971, с. 22-24. * |
| Машковский М. Д., Лекарственные средства, Кишинев, Штиинца, 1990, Ч. 2, с. 352,360,371. * |
| Рубцов М. А., Байчиков А. Г., Синтетические химико-фармацевтические препараты, Москва, Медицина, 1971, с.77-81. * |
Also Published As
| Publication number | Publication date |
|---|---|
| MD1574B1 (ro) | 2000-12-31 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MM4A | Patent for invention definitely lapsed due to non-payment of fees |