MD143C2 - Derivaţi ai oxadiazolilalchilpurinei, care manifestă activitate antitusivă - Google Patents
Derivaţi ai oxadiazolilalchilpurinei, care manifestă activitate antitusivăInfo
- Publication number
- MD143C2 MD143C2 MD94-0166A MD940166A MD143C2 MD 143 C2 MD143 C2 MD 143C2 MD 940166 A MD940166 A MD 940166A MD 143 C2 MD143 C2 MD 143C2
- Authority
- MD
- Moldova
- Prior art keywords
- activity
- hcl
- oxadiazolylalkylpurine
- och3
- cough
- Prior art date
Links
- 230000000694 effects Effects 0.000 title abstract 3
- 206010011224 Cough Diseases 0.000 title abstract 2
- CSCPPACGZOOCGX-UHFFFAOYSA-N Acetone Chemical compound CC(C)=O CSCPPACGZOOCGX-UHFFFAOYSA-N 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- VGCXGMAHQTYDJK-UHFFFAOYSA-N Chloroacetyl chloride Chemical compound ClCC(Cl)=O VGCXGMAHQTYDJK-UHFFFAOYSA-N 0.000 abstract 1
- 239000011149 active material Substances 0.000 abstract 1
- 230000010933 acylation Effects 0.000 abstract 1
- 238000005917 acylation reaction Methods 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 230000000903 blocking effect Effects 0.000 abstract 1
- WBLIXGSTEMXDSM-UHFFFAOYSA-N chloromethane Chemical compound Cl[CH2] WBLIXGSTEMXDSM-UHFFFAOYSA-N 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 125000000623 heterocyclic group Chemical group 0.000 abstract 1
- 125000000956 methoxy group Chemical group [H]C([H])([H])O* 0.000 abstract 1
- 230000029058 respiratory gaseous exchange Effects 0.000 abstract 1
- 229910000029 sodium carbonate Inorganic materials 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
- 238000003786 synthesis reaction Methods 0.000 abstract 1
- 230000001988 toxicity Effects 0.000 abstract 1
- 231100000419 toxicity Toxicity 0.000 abstract 1
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| HU864230A HU197574B (en) | 1986-10-09 | 1986-10-09 | Process for production of derivatives of 3,7-dihydro-3-methil-7-//1,2,4-oxadiasole/-3-il/alkylenil/-1h-purin-2,6-dion and medical compositions containing these substances |
| SU884355201A SU1602862A1 (ru) | 1986-10-09 | 1988-02-19 | Производные оксадиазолилалкилпурина, про вл ющие противокашлевую активность |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| MD143B1 MD143B1 (ro) | 1995-01-30 |
| MD143C2 true MD143C2 (ro) | 1995-07-31 |
Family
ID=26317750
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MD94-0166A MD143C2 (ro) | 1986-10-09 | 1994-04-21 | Derivaţi ai oxadiazolilalchilpurinei, care manifestă activitate antitusivă |
Country Status (3)
| Country | Link |
|---|---|
| LT (1) | LT2580B (lt) |
| LV (1) | LV5262A3 (lt) |
| MD (1) | MD143C2 (lt) |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SU1344756A1 (ru) * | 1982-03-12 | 1987-10-15 | Хиноин Дьедьсер Еш Ведьесети Термекек Дьяра Рт (Инопредприятие) | Производные теофиллина или их соли,обладающие успокаивающим кашель действием |
-
1993
- 1993-06-08 LV LV930484A patent/LV5262A3/xx unknown
- 1993-06-12 LT LTRP652A patent/LT2580B/lt not_active IP Right Cessation
-
1994
- 1994-04-21 MD MD94-0166A patent/MD143C2/ro active IP Right Grant
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SU1344756A1 (ru) * | 1982-03-12 | 1987-10-15 | Хиноин Дьедьсер Еш Ведьесети Термекек Дьяра Рт (Инопредприятие) | Производные теофиллина или их соли,обладающие успокаивающим кашель действием |
Non-Patent Citations (2)
| Title |
|---|
| Atzneimittel-Forschung, 617-621, 1966- * |
| Rev. Chem. Res. (M), 1979, 801. * |
Also Published As
| Publication number | Publication date |
|---|---|
| MD143B1 (ro) | 1995-01-30 |
| LV5262A3 (lv) | 1993-10-10 |
| LT2580B (lt) | 1994-03-25 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG4A | Patent for invention issued | ||
| IF99 | Valid patent on 19990615 |
Free format text: EXPIRES: 20080218 |