MD1046Z - Метод прогнозирования риска возникновения кардиоваскулярной автономной нейропатии при сахарном диабете I-го типа - Google Patents
Метод прогнозирования риска возникновения кардиоваскулярной автономной нейропатии при сахарном диабете I-го типа Download PDFInfo
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- MD1046Z MD1046Z MDS20150126A MDS20150126A MD1046Z MD 1046 Z MD1046 Z MD 1046Z MD S20150126 A MDS20150126 A MD S20150126A MD S20150126 A MDS20150126 A MD S20150126A MD 1046 Z MD1046 Z MD 1046Z
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- MD
- Moldova
- Prior art keywords
- risk
- autonomic neuropathy
- type
- cardiovascular autonomic
- diabetes mellitus
- Prior art date
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- 230000002526 effect on cardiovascular system Effects 0.000 title claims abstract description 34
- 206010061666 Autonomic neuropathy Diseases 0.000 title claims abstract description 32
- 206010067584 Type 1 diabetes mellitus Diseases 0.000 title claims abstract description 18
- 238000000034 method Methods 0.000 title claims abstract description 18
- 206010012601 diabetes mellitus Diseases 0.000 claims abstract description 13
- 208000001380 Diabetic Ketoacidosis Diseases 0.000 claims abstract description 7
- 201000001119 neuropathy Diseases 0.000 claims abstract description 3
- 230000007823 neuropathy Effects 0.000 claims abstract description 3
- 208000033808 peripheral neuropathy Diseases 0.000 claims abstract description 3
- 208000007342 Diabetic Nephropathies Diseases 0.000 claims description 7
- 208000033679 diabetic kidney disease Diseases 0.000 claims description 7
- 239000003814 drug Substances 0.000 abstract description 2
- 208000017169 kidney disease Diseases 0.000 abstract 1
- 230000006870 function Effects 0.000 description 9
- 238000012360 testing method Methods 0.000 description 8
- 238000003745 diagnosis Methods 0.000 description 7
- 230000002349 favourable effect Effects 0.000 description 6
- 238000004393 prognosis Methods 0.000 description 6
- 206010023379 Ketoacidosis Diseases 0.000 description 3
- 208000007976 Ketosis Diseases 0.000 description 3
- 238000004458 analytical method Methods 0.000 description 3
- 238000001514 detection method Methods 0.000 description 3
- 206010066001 Cardiac autonomic neuropathy Diseases 0.000 description 2
- 230000000747 cardiac effect Effects 0.000 description 2
- 238000012937 correction Methods 0.000 description 2
- 238000011161 development Methods 0.000 description 2
- 230000002641 glycemic effect Effects 0.000 description 2
- LELAOEBVZLPXAZ-UHFFFAOYSA-N iberin Chemical compound CS(=O)CCCN=C=S LELAOEBVZLPXAZ-UHFFFAOYSA-N 0.000 description 2
- 230000006872 improvement Effects 0.000 description 2
- 238000011160 research Methods 0.000 description 2
- 238000012216 screening Methods 0.000 description 2
- 230000001225 therapeutic effect Effects 0.000 description 2
- 208000002249 Diabetes Complications Diseases 0.000 description 1
- 208000032131 Diabetic Neuropathies Diseases 0.000 description 1
- 230000037424 autonomic function Effects 0.000 description 1
- 230000008901 benefit Effects 0.000 description 1
- 230000036772 blood pressure Effects 0.000 description 1
- 238000007405 data analysis Methods 0.000 description 1
- 238000002405 diagnostic procedure Methods 0.000 description 1
- 230000002218 hypoglycaemic effect Effects 0.000 description 1
- 238000011835 investigation Methods 0.000 description 1
- 238000013178 mathematical model Methods 0.000 description 1
- 230000004060 metabolic process Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 230000007170 pathology Effects 0.000 description 1
- 230000001681 protective effect Effects 0.000 description 1
- 230000004044 response Effects 0.000 description 1
- 238000012552 review Methods 0.000 description 1
- 230000035945 sensitivity Effects 0.000 description 1
- 208000024891 symptom Diseases 0.000 description 1
- 238000011282 treatment Methods 0.000 description 1
- 238000011269 treatment regimen Methods 0.000 description 1
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- Investigating Or Analysing Biological Materials (AREA)
Abstract
Изобретение относится к медицине, в частности к эндокринологии и может быть использовано для прогнозирования риска возникновения кардиоваскулярной автономной нейропатии при сахарном диабете I-го типа.Метод, согласно изобретению, включает клиническое и параклиническое обследование, где устанавливаются следующие параметры: тяжесть диабетической нефропатии (ND), частота возникновения диабетического кетоацидоза (CAD), длительность сахарного диабета (DD), затем вычисляют дискриминантную функцию (F) согласно формуле:F=-4,972+1,767·ND+1,530·CAD+0,078·DD,в случае, когда F > 0, прогнозируется риск возникновения кардиоваскулярной автономной нейропатии при сахарном диабете I-го типа, а когда F < 0 - прогнозируется отсутствие риска возникновения нейропатии.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| MDS20150126A MD1046Z (ru) | 2015-09-11 | 2015-09-11 | Метод прогнозирования риска возникновения кардиоваскулярной автономной нейропатии при сахарном диабете I-го типа |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| MDS20150126A MD1046Z (ru) | 2015-09-11 | 2015-09-11 | Метод прогнозирования риска возникновения кардиоваскулярной автономной нейропатии при сахарном диабете I-го типа |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| MD1046Y MD1046Y (ru) | 2016-06-30 |
| MD1046Z true MD1046Z (ru) | 2017-01-31 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MDS20150126A MD1046Z (ru) | 2015-09-11 | 2015-09-11 | Метод прогнозирования риска возникновения кардиоваскулярной автономной нейропатии при сахарном диабете I-го типа |
Country Status (1)
| Country | Link |
|---|---|
| MD (1) | MD1046Z (ru) |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| UA7348U (en) * | 2004-12-03 | 2005-06-15 | Andrii Semenovych Yefimov | Method for assessing stage of diabetic cardiovascular autonomic neuropathy |
| MD833Y (ru) * | 2014-05-15 | 2014-11-30 | Константин ЖУКОВСКИЙ | Метод раннего прогнозирования течения острого инфаркта миокарда у больных с сахарным диабетом |
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2015
- 2015-09-11 MD MDS20150126A patent/MD1046Z/ru not_active IP Right Cessation
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| UA7348U (en) * | 2004-12-03 | 2005-06-15 | Andrii Semenovych Yefimov | Method for assessing stage of diabetic cardiovascular autonomic neuropathy |
| MD833Y (ru) * | 2014-05-15 | 2014-11-30 | Константин ЖУКОВСКИЙ | Метод раннего прогнозирования течения острого инфаркта миокарда у больных с сахарным диабетом |
Non-Patent Citations (1)
| Title |
|---|
| Spallone V., Ziegler D., Freeman R., et. al. on behalf of the Toronto Consensus Panel on Diabetic neuropaty, Cardiovascular autonomic neuropathy in diabetes: clinical impact, assessment, diagnosis, and management. Diabetes Metabolism Research and Reviews, 2011, 27, p. 639-653 * |
Also Published As
| Publication number | Publication date |
|---|---|
| MD1046Y (ru) | 2016-06-30 |
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| Date | Code | Title | Description |
|---|---|---|---|
| FG9Y | Short term patent issued | ||
| KA4Y | Short-term patent lapsed due to non-payment of fees (with right of restoration) |