MA59341A1 - Rifamycin analogs and antibody-drug conjugates thereof - Google Patents
Rifamycin analogs and antibody-drug conjugates thereofInfo
- Publication number
- MA59341A1 MA59341A1 MA59341A MA59341A MA59341A1 MA 59341 A1 MA59341 A1 MA 59341A1 MA 59341 A MA59341 A MA 59341A MA 59341 A MA59341 A MA 59341A MA 59341 A1 MA59341 A1 MA 59341A1
- Authority
- MA
- Morocco
- Prior art keywords
- antibody
- drug conjugates
- growth
- infections
- aureus
- Prior art date
Links
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- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
L'invention concerne des composés analogues de rifamycine, des intermédiaires et des précurseurs de ceux-ci, et des compositions pharmaceutiques capables d'inhiber la croissance bactérienne (par exemple, la croissance de s. Aureus) et de traiter des infections bactériennes (par exemple, des infections par s. Aureus). L'invention concerne en outre des conjugués anticorps-médicament de composés analogues de rifamycine et d'anticorps, par exemple, des anticorps spécifiques contre des cibles associées à une maladie infectieuse comme le récepteur de glycoprotéine membranaire (msr1), des acides téichoïques de paroi (wta) ou une protéine a, et des procédés d'utilisation de ceux-ci pour inhiber la croissance bactérienne et traiter des infections bactériennes.Disclosed herein are rifamycin analog compounds, intermediates and precursors thereof, and pharmaceutical compositions capable of inhibiting bacterial growth (eg, growth of S. Aureus) and treating bacterial infections (eg. example, S. Aureus infections). The invention further relates to antibody-drug conjugates of rifamycin analog compounds and antibodies, for example, antibodies specific against targets associated with infectious disease such as the membrane glycoprotein receptor (msr1), cell wall teichoic acids (wta) or a protein, and methods of using the same to inhibit bacterial growth and treat bacterial infections.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201862783506P | 2018-12-21 | 2018-12-21 |
Publications (1)
Publication Number | Publication Date |
---|---|
MA59341A1 true MA59341A1 (en) | 2023-05-31 |
Family
ID=83598749
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MA53783A MA53783A1 (en) | 2018-12-21 | 2019-12-20 | Rifamycin analogs and antibody-drug conjugates thereof |
MA59341A MA59341A1 (en) | 2018-12-21 | 2021-07-28 | Rifamycin analogs and antibody-drug conjugates thereof |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MA53783A MA53783A1 (en) | 2018-12-21 | 2019-12-20 | Rifamycin analogs and antibody-drug conjugates thereof |
Country Status (1)
Country | Link |
---|---|
MA (2) | MA53783A1 (en) |
-
2019
- 2019-12-20 MA MA53783A patent/MA53783A1/en unknown
-
2021
- 2021-07-28 MA MA59341A patent/MA59341A1/en unknown
Also Published As
Publication number | Publication date |
---|---|
MA53783A1 (en) | 2022-09-30 |
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