MA56507A - Nouveaux inhibiteurs d'egfr - Google Patents

Nouveaux inhibiteurs d'egfr

Info

Publication number
MA56507A
MA56507A MA056507A MA56507A MA56507A MA 56507 A MA56507 A MA 56507A MA 056507 A MA056507 A MA 056507A MA 56507 A MA56507 A MA 56507A MA 56507 A MA56507 A MA 56507A
Authority
MA
Morocco
Prior art keywords
egfr inhibitors
new egfr
new
inhibitors
egfr
Prior art date
Application number
MA056507A
Other languages
English (en)
Inventor
Cosimo Dolente
Annick Goergler
David Stephen Hewings
Georg Jaeschke
Bernd Kuhn
Yvonne Alice Nagel
Roger David Norcross
Christa Ulrike Obst-Sander
Antonio Ricci
Daniel Rueher
Sandra Steiner
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of MA56507A publication Critical patent/MA56507A/fr

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425Thiazoles
    • A61K31/427Thiazoles not condensed and containing further heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445Non condensed piperidines, e.g. piperocaine
    • A61K31/4523Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/454Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Steroid Compounds (AREA)
MA056507A 2019-06-21 2020-06-19 Nouveaux inhibiteurs d'egfr MA56507A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP19181772 2019-06-21

Publications (1)

Publication Number Publication Date
MA56507A true MA56507A (fr) 2022-04-27

Family

ID=67001684

Family Applications (1)

Application Number Title Priority Date Filing Date
MA056507A MA56507A (fr) 2019-06-21 2020-06-19 Nouveaux inhibiteurs d'egfr

Country Status (19)

Country Link
US (2) US20220315591A1 (fr)
EP (2) EP3986566B1 (fr)
JP (2) JP2022537772A (fr)
KR (1) KR20220024096A (fr)
CN (2) CN113993590A (fr)
AR (2) AR119207A1 (fr)
AU (1) AU2020296933A1 (fr)
BR (1) BR112021024810A2 (fr)
CA (1) CA3139171A1 (fr)
CL (1) CL2021003373A1 (fr)
CO (1) CO2021016967A2 (fr)
CR (1) CR20210614A (fr)
IL (1) IL287806A (fr)
MA (1) MA56507A (fr)
MX (1) MX2021015889A (fr)
PE (1) PE20220807A1 (fr)
TW (2) TW202115070A (fr)
WO (2) WO2020254546A1 (fr)
ZA (1) ZA202108775B (fr)

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2728210A1 (fr) 2008-06-25 2009-12-30 Schering Corporation Synthese et utilisation d'agents antibacteriens heterocycliques
US8420661B2 (en) 2010-04-13 2013-04-16 Hoffmann-La Roche Inc. Arylethynyl derivatives
SG11201708820TA (en) 2015-05-14 2017-11-29 Wistar Inst Ebna1 inhibitors and methods using same
AU2016288204B2 (en) * 2015-06-30 2020-11-05 Dana-Farber Cancer Institute, Inc. Inhibitors of EGFR and methods of use thereof
WO2018220149A1 (fr) * 2017-06-02 2018-12-06 F. Hoffmann-La Roche Ag Composés
EP3814351A1 (fr) * 2018-06-29 2021-05-05 F. Hoffmann-La Roche AG Composés

Also Published As

Publication number Publication date
MX2021015889A (es) 2022-02-03
TW202115073A (zh) 2021-04-16
WO2020254547A1 (fr) 2020-12-24
KR20220024096A (ko) 2022-03-03
AR119207A1 (es) 2021-12-01
BR112021024810A2 (pt) 2022-01-25
TW202115070A (zh) 2021-04-16
EP3986567C0 (fr) 2023-08-30
CN113993591A (zh) 2022-01-28
AU2020296933A1 (en) 2021-12-02
EP3986566B1 (fr) 2023-08-30
EP3986567A1 (fr) 2022-04-27
JP2022537771A (ja) 2022-08-29
US20220112199A1 (en) 2022-04-14
US20220315591A1 (en) 2022-10-06
CR20210614A (es) 2022-02-11
CL2021003373A1 (es) 2022-10-07
EP3986566A1 (fr) 2022-04-27
PE20220807A1 (es) 2022-05-20
JP2022537772A (ja) 2022-08-29
CN113993590A (zh) 2022-01-28
AR121167A1 (es) 2022-04-27
EP3986567B1 (fr) 2023-08-30
CA3139171A1 (fr) 2020-12-24
ZA202108775B (en) 2022-09-28
EP3986566C0 (fr) 2023-08-30
WO2020254546A1 (fr) 2020-12-24
IL287806A (en) 2022-01-01
CO2021016967A2 (es) 2022-01-17

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