MA56185A - Nouveaux intermédiaires spirobicycliques - Google Patents
Nouveaux intermédiaires spirobicycliquesInfo
- Publication number
- MA56185A MA56185A MA056185A MA56185A MA56185A MA 56185 A MA56185 A MA 56185A MA 056185 A MA056185 A MA 056185A MA 56185 A MA56185 A MA 56185A MA 56185 A MA56185 A MA 56185A
- Authority
- MA
- Morocco
- Prior art keywords
- spirobicyclic
- intermediates
- new
- spirobicyclic intermediates
- new spirobicyclic
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H23/00—Compounds containing boron, silicon, or a metal, e.g. chelates, vitamin B12
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/02—Acyclic radicals, not substituted by cyclic structures
- C07H15/04—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/18—Acyclic radicals, substituted by carbocyclic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/16—Purine radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H7/00—Compounds containing non-saccharide radicals linked to saccharide radicals by a carbon-to-carbon bond
- C07H7/04—Carbocyclic radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H9/00—Compounds containing a hetero ring sharing at least two hetero atoms with a saccharide radical
- C07H9/02—Compounds containing a hetero ring sharing at least two hetero atoms with a saccharide radical the hetero ring containing only oxygen as ring hetero atoms
- C07H9/04—Cyclic acetals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Crystallography & Structural Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Saccharide Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IN201911023295 | 2019-06-12 | ||
| EP19193707 | 2019-08-27 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MA56185A true MA56185A (fr) | 2022-04-20 |
Family
ID=71120144
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MA056185A MA56185A (fr) | 2019-06-12 | 2020-06-11 | Nouveaux intermédiaires spirobicycliques |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US20220275018A1 (es) |
| EP (1) | EP3983393A1 (es) |
| JP (1) | JP2022536712A (es) |
| KR (1) | KR20220019766A (es) |
| CN (1) | CN113966328A (es) |
| AU (1) | AU2020290672A1 (es) |
| BR (1) | BR112021024457A2 (es) |
| CA (1) | CA3138349A1 (es) |
| CR (1) | CR20220012A (es) |
| EC (1) | ECSP21089373A (es) |
| IL (1) | IL288741A (es) |
| JO (1) | JOP20210327A1 (es) |
| MA (1) | MA56185A (es) |
| MX (1) | MX2021015363A (es) |
| PE (1) | PE20220433A1 (es) |
| WO (1) | WO2020249663A1 (es) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2024170488A1 (en) | 2023-02-13 | 2024-08-22 | Astrazeneca Ab | Prmt5 inhibitor for use in cancer therapy |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6143749A (en) | 1995-06-07 | 2000-11-07 | Abbott Laboratories | Heterocyclic substituted cyclopentane compounds |
| CN101392012A (zh) | 2002-02-19 | 2009-03-25 | Cv医药有限公司 | A1腺苷受体的部分和全促效药 |
| US20040043959A1 (en) | 2002-03-04 | 2004-03-04 | Bloom Laura A. | Combination therapies for treating methylthioadenosine phosphorylase deficient cells |
| CA2819620A1 (en) | 2010-12-03 | 2012-06-21 | Epizyme, Inc. | Modulators of histone methyltransferase, and methods of use thereof |
| WO2012075500A2 (en) | 2010-12-03 | 2012-06-07 | Epizyme, Inc. | 7-deazapurine modulators of histone methyltransferase, and methods of use thereof |
| WO2014035140A2 (en) | 2012-08-30 | 2014-03-06 | Kainos Medicine, Inc. | Compounds and compositions for modulating histone methyltransferase activity |
| US8940726B2 (en) | 2012-12-21 | 2015-01-27 | Epizyme, Inc. | PRMT5 inhibitors and uses thereof |
| JP6678455B2 (ja) | 2012-12-21 | 2020-04-08 | エピザイム，インコーポレイティド | Ｐｒｍｔ５阻害剤およびその使用 |
| US9908887B2 (en) | 2012-12-21 | 2018-03-06 | Epizyme, Inc. | PRMT5 inhibitors and uses thereof |
| US20170198006A1 (en) | 2014-06-25 | 2017-07-13 | Epizyme, Inc. | Prmt5 inhibitors and uses thereof |
| WO2016135582A1 (en) | 2015-02-24 | 2016-09-01 | Pfizer Inc. | Substituted nucleoside derivatives useful as anticancer agents |
| TWI791251B (zh) | 2015-08-26 | 2023-02-01 | 比利時商健生藥品公司 | 使用作為ｐｒｍｔ５抑制劑之新穎經６-６雙環芳香環取代之核苷類似物 |
| CN108884108B (zh) * | 2016-03-10 | 2021-08-31 | 詹森药业有限公司 | 用于用作prmt5抑制剂的取代核苷类似物 |
| WO2018065365A1 (en) | 2016-10-03 | 2018-04-12 | Janssen Pharmaceutica Nv | Novel monocyclic and bicyclic ring system substituted carbanucleoside analogues for use as prmt5 inhibitors |
| IL275129B2 (en) * | 2017-12-08 | 2023-10-01 | Janssen Pharmaceutica Nv | New spirobicyclic analogs |
-
2020
- 2020-06-11 CA CA3138349A patent/CA3138349A1/en active Pending
- 2020-06-11 JP JP2021573512A patent/JP2022536712A/ja active Pending
- 2020-06-11 AU AU2020290672A patent/AU2020290672A1/en active Pending
- 2020-06-11 PE PE2021002041A patent/PE20220433A1/es unknown
- 2020-06-11 CR CR20220012A patent/CR20220012A/es unknown
- 2020-06-11 MA MA056185A patent/MA56185A/fr unknown
- 2020-06-11 KR KR1020227000490A patent/KR20220019766A/ko active Search and Examination
- 2020-06-11 MX MX2021015363A patent/MX2021015363A/es unknown
- 2020-06-11 WO PCT/EP2020/066182 patent/WO2020249663A1/en active Application Filing
- 2020-06-11 JO JOP/2021/0327A patent/JOP20210327A1/ar unknown
- 2020-06-11 EP EP20734118.1A patent/EP3983393A1/en active Pending
- 2020-06-11 US US17/616,248 patent/US20220275018A1/en active Pending
- 2020-06-11 BR BR112021024457A patent/BR112021024457A2/pt unknown
- 2020-06-11 CN CN202080042994.7A patent/CN113966328A/zh active Pending
-
2021
- 2021-12-07 IL IL288741A patent/IL288741A/en unknown
- 2021-12-10 EC ECSENADI202189373A patent/ECSP21089373A/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| IL288741A (en) | 2022-02-01 |
| MX2021015363A (es) | 2022-04-06 |
| BR112021024457A2 (pt) | 2022-01-18 |
| KR20220019766A (ko) | 2022-02-17 |
| AU2020290672A1 (en) | 2022-02-10 |
| EP3983393A1 (en) | 2022-04-20 |
| PE20220433A1 (es) | 2022-03-29 |
| JOP20210327A1 (ar) | 2023-01-30 |
| ECSP21089373A (es) | 2022-01-31 |
| CA3138349A1 (en) | 2020-12-17 |
| US20220275018A1 (en) | 2022-09-01 |
| CN113966328A (zh) | 2022-01-21 |
| CR20220012A (es) | 2022-03-11 |
| JP2022536712A (ja) | 2022-08-18 |
| WO2020249663A1 (en) | 2020-12-17 |
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