MA51146B1 - Composés hétérocycliques bicycliques substitués utilisés en tant qu'inhibiteurs de prmt5 - Google Patents
Composés hétérocycliques bicycliques substitués utilisés en tant qu'inhibiteurs de prmt5Info
- Publication number
- MA51146B1 MA51146B1 MA51146A MA51146A MA51146B1 MA 51146 B1 MA51146 B1 MA 51146B1 MA 51146 A MA51146 A MA 51146A MA 51146 A MA51146 A MA 51146A MA 51146 B1 MA51146 B1 MA 51146B1
- Authority
- MA
- Morocco
- Prior art keywords
- heterocyclic compounds
- substituted heterocyclic
- compounds used
- prmt5 inhibitors
- bicyclic substituted
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4709—Non-condensed quinolines and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
L'invention concerne des composés hétérocycliques bicycliques substitués de formule (i), des sels pharmaceutiquement acceptables de ceux-ci et des compositions pharmaceutiques pour le traitement de maladies, de troubles ou d'états pathologiques associés à la surexpression de l'enzyme prmt5. L'invention concerne également des méthodes de traitement de maladies, de troubles ou d'états pathologiques associés à la surexpression de l'enzyme prmt5.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IN201721044886 | 2017-12-13 | ||
PCT/IB2018/060015 WO2019116302A1 (fr) | 2017-12-13 | 2018-12-13 | Composés hétérocycliques bicycliques substitués utilisés en tant qu'inhibiteurs de prmt5 |
Publications (2)
Publication Number | Publication Date |
---|---|
MA51146A MA51146A (fr) | 2021-03-24 |
MA51146B1 true MA51146B1 (fr) | 2022-10-31 |
Family
ID=83995765
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MA51146A MA51146B1 (fr) | 2017-12-13 | 2018-12-13 | Composés hétérocycliques bicycliques substitués utilisés en tant qu'inhibiteurs de prmt5 |
Country Status (1)
Country | Link |
---|---|
MA (1) | MA51146B1 (fr) |
-
2018
- 2018-12-13 MA MA51146A patent/MA51146B1/fr unknown
Also Published As
Publication number | Publication date |
---|---|
MA51146A (fr) | 2021-03-24 |
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