MA49352A - Séquençage de bibliothèque de polynucléotides à haut rendement et analyse de transcriptome - Google Patents
Séquençage de bibliothèque de polynucléotides à haut rendement et analyse de transcriptomeInfo
- Publication number
- MA49352A MA49352A MA049352A MA49352A MA49352A MA 49352 A MA49352 A MA 49352A MA 049352 A MA049352 A MA 049352A MA 49352 A MA49352 A MA 49352A MA 49352 A MA49352 A MA 49352A
- Authority
- MA
- Morocco
- Prior art keywords
- high yield
- transcriptome analysis
- polynucleotide library
- library sequencing
- yield polynucleotide
- Prior art date
Links
- 102000040430 polynucleotide Human genes 0.000 title 1
- 108091033319 polynucleotide Proteins 0.000 title 1
- 239000002157 polynucleotide Substances 0.000 title 1
- 238000012163 sequencing technique Methods 0.000 title 1
- 238000011222 transcriptome analysis Methods 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
- C12Q1/6853—Nucleic acid amplification reactions using modified primers or templates
- C12Q1/6855—Ligating adaptors
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2525/00—Reactions involving modified oligonucleotides, nucleic acids, or nucleotides
- C12Q2525/10—Modifications characterised by
- C12Q2525/155—Modifications characterised by incorporating/generating a new priming site
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2525/00—Reactions involving modified oligonucleotides, nucleic acids, or nucleotides
- C12Q2525/10—Modifications characterised by
- C12Q2525/179—Modifications characterised by incorporating arbitrary or random nucleotide sequences
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2525/00—Reactions involving modified oligonucleotides, nucleic acids, or nucleotides
- C12Q2525/10—Modifications characterised by
- C12Q2525/191—Modifications characterised by incorporating an adaptor
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2563/00—Nucleic acid detection characterized by the use of physical, structural and functional properties
- C12Q2563/159—Microreactors, e.g. emulsion PCR or sequencing, droplet PCR, microcapsules, i.e. non-liquid containers with a range of different permeability's for different reaction components
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2563/00—Nucleic acid detection characterized by the use of physical, structural and functional properties
- C12Q2563/179—Nucleic acid detection characterized by the use of physical, structural and functional properties the label being a nucleic acid
-
- C—CHEMISTRY; METALLURGY
- C40—COMBINATORIAL TECHNOLOGY
- C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
- C40B40/00—Libraries per se, e.g. arrays, mixtures
- C40B40/04—Libraries containing only organic compounds
- C40B40/06—Libraries containing nucleotides or polynucleotides, or derivatives thereof
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Biotechnology (AREA)
- Analytical Chemistry (AREA)
- Physics & Mathematics (AREA)
- Microbiology (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762511949P | 2017-05-26 | 2017-05-26 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MA49352A true MA49352A (fr) | 2020-04-08 |
Family
ID=62621068
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MA049352A MA49352A (fr) | 2017-05-26 | 2018-05-25 | Séquençage de bibliothèque de polynucléotides à haut rendement et analyse de transcriptome |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US12049667B2 (fr) |
| EP (1) | EP3631012B1 (fr) |
| JP (1) | JP7308187B2 (fr) |
| KR (1) | KR102550778B1 (fr) |
| CN (1) | CN111148849A (fr) |
| AU (1) | AU2018273999A1 (fr) |
| CA (1) | CA3064205A1 (fr) |
| ES (1) | ES2926722T3 (fr) |
| MA (1) | MA49352A (fr) |
| WO (1) | WO2018218222A1 (fr) |
Families Citing this family (57)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8835358B2 (en) | 2009-12-15 | 2014-09-16 | Cellular Research, Inc. | Digital counting of individual molecules by stochastic attachment of diverse labels |
| US10941396B2 (en) | 2012-02-27 | 2021-03-09 | Becton, Dickinson And Company | Compositions and kits for molecular counting |
| ES2711168T3 (es) | 2013-08-28 | 2019-04-30 | Becton Dickinson Co | Análisis masivo en paralelo de células individuales |
| WO2016138496A1 (fr) | 2015-02-27 | 2016-09-01 | Cellular Research, Inc. | Codage à barres moléculaire à adressage spatial |
| WO2016160844A2 (fr) | 2015-03-30 | 2016-10-06 | Cellular Research, Inc. | Procédés et compositions pour codage à barres combinatoire |
| CN108026524A (zh) | 2015-09-11 | 2018-05-11 | 赛卢拉研究公司 | 用于核酸文库标准化的方法和组合物 |
| US10301677B2 (en) | 2016-05-25 | 2019-05-28 | Cellular Research, Inc. | Normalization of nucleic acid libraries |
| US10640763B2 (en) | 2016-05-31 | 2020-05-05 | Cellular Research, Inc. | Molecular indexing of internal sequences |
| US10202641B2 (en) | 2016-05-31 | 2019-02-12 | Cellular Research, Inc. | Error correction in amplification of samples |
| CA3034924C (fr) | 2016-09-26 | 2025-11-18 | Becton, Dickinson And Company | Mesure d'expression de proteines a l'aide de reactifs avec des sequences d'oligonucleotides a code-barres |
| CN110382708A (zh) | 2017-02-01 | 2019-10-25 | 赛卢拉研究公司 | 使用阻断性寡核苷酸进行选择性扩增 |
| ES2926722T3 (es) | 2017-05-26 | 2022-10-27 | Abvitro Llc | Secuenciación de alto rendimiento de biblioteca de polinucleótidos y análisis de transcriptoma |
| JP7536450B2 (ja) | 2017-06-05 | 2024-08-20 | ベクトン・ディキンソン・アンド・カンパニー | 単一細胞用のサンプルインデックス付加 |
| EP3788170B1 (fr) | 2018-05-03 | 2025-01-01 | Becton, Dickinson and Company | Codage à barres moléculaire sur des extrémités de transcrit en regard |
| CA3097976A1 (fr) | 2018-05-03 | 2019-11-07 | Becton, Dickinson And Company | Analyse multi-omique d'echantillons a haut debit |
| ES2992135T3 (es) | 2018-10-01 | 2024-12-09 | Becton Dickinson Co | Determinar secuencias de transcripción 5 |
| JP7618548B2 (ja) | 2018-11-08 | 2025-01-21 | ベクトン・ディキンソン・アンド・カンパニー | ランダムプライミングを使用した単一細胞の全トランスクリプトーム解析 |
| US11492660B2 (en) | 2018-12-13 | 2022-11-08 | Becton, Dickinson And Company | Selective extension in single cell whole transcriptome analysis |
| KR20210141449A (ko) * | 2018-12-28 | 2021-11-23 | 내셔널 유니버시티 오브 싱가포르 | 표적화된 상보적 dna 강화를 위한 방법 |
| EP4242322B1 (fr) | 2019-01-23 | 2024-08-21 | Becton, Dickinson and Company | Oligonucléotides associés à des anticorps |
| CN113454234B (zh) | 2019-02-14 | 2025-03-18 | 贝克顿迪金森公司 | 杂合体靶向和全转录物组扩增 |
| CN120099137A (zh) | 2019-07-22 | 2025-06-06 | 贝克顿迪金森公司 | 单细胞染色质免疫沉淀测序测定 |
| JP2022543278A (ja) * | 2019-08-05 | 2022-10-11 | ミッション バイオ インコーポレイテッド | 細胞軌道を測定するためのシングルセル分析のための方法及び装置 |
| JP7712919B2 (ja) * | 2019-10-09 | 2025-07-24 | エドワード フリッチュ， | マルチドメインタンパク質ワクチン |
| JP7522189B2 (ja) * | 2019-11-08 | 2024-07-24 | ベクトン・ディキンソン・アンド・カンパニー | 免疫レパートリーシーケンシングのための完全長ｖ（ｄ）ｊ情報を得るためのランダムプライミングの使用 |
| US12163189B2 (en) | 2019-11-27 | 2024-12-10 | University Of Washington | Method for preparation and high-throughput microbial single-cell RNA sequencing of bacteria |
| EP4090764A1 (fr) | 2020-01-13 | 2022-11-23 | Becton, Dickinson and Company | Capture de cellules à l'aide d'oligonucléotides contenant de la du |
| US11649497B2 (en) | 2020-01-13 | 2023-05-16 | Becton, Dickinson And Company | Methods and compositions for quantitation of proteins and RNA |
| WO2021155057A1 (fr) | 2020-01-29 | 2021-08-05 | Becton, Dickinson And Company | Puits à code-barres pour la cartographie spatiale de cellules individuelles par séquençage |
| WO2021168015A1 (fr) * | 2020-02-17 | 2021-08-26 | Universal Sequencing Technology Corporation | Procédés de codage à barres d'acide nucléique pour la détection et le séquençage |
| EP4111168A1 (fr) | 2020-02-25 | 2023-01-04 | Becton Dickinson and Company | Sondes bi-spécifiques permettant l'utilisation d'échantillons monocellulaires en tant que contrôle de compensation de couleur unique |
| EP4150118A1 (fr) | 2020-05-14 | 2023-03-22 | Becton Dickinson and Company | Amorces pour profilage de répertoire immunitaire |
| CA3178970A1 (fr) * | 2020-05-20 | 2021-11-25 | Sinan ARSLAN | Procedes de preparation de bibliotheque de sequencage en paire |
| CA3185619A1 (fr) * | 2020-05-29 | 2021-12-02 | Riken | Procede de traitement d'une population cellulaire et procede d'analyse de genes inclus dans une population cellulaire |
| US12157913B2 (en) | 2020-06-02 | 2024-12-03 | Becton, Dickinson And Company | Oligonucleotides and beads for 5 prime gene expression assay |
| KR102468839B1 (ko) * | 2020-06-03 | 2022-11-18 | 주식회사 제노헬릭스 | Rna 검출 방법 |
| CN111549025B (zh) * | 2020-06-08 | 2021-09-14 | 郑州大学第一附属医院 | 链置换引物和细胞转录组文库构建方法 |
| US11932901B2 (en) | 2020-07-13 | 2024-03-19 | Becton, Dickinson And Company | Target enrichment using nucleic acid probes for scRNAseq |
| WO2022026909A1 (fr) | 2020-07-31 | 2022-02-03 | Becton, Dickinson And Company | Dosage à cellule unique pour chromatine accessible par transposase |
| AU2021338364A1 (en) * | 2020-09-07 | 2023-03-30 | Berkeley Lights, Inc. | Methods of assaying a biological cell |
| US20230399693A1 (en) * | 2020-11-03 | 2023-12-14 | Act Genomics (Ip) Co., Limited | Targeted sequencing method and kit thereof for detecting gene alteration |
| US11739443B2 (en) | 2020-11-20 | 2023-08-29 | Becton, Dickinson And Company | Profiling of highly expressed and lowly expressed proteins |
| US12378596B2 (en) * | 2020-12-03 | 2025-08-05 | Roche Sequencing Solutions, Inc. | Whole transcriptome analysis in single cells |
| EP4263859A1 (fr) | 2020-12-15 | 2023-10-25 | Becton, Dickinson and Company | Analyse du sécrétome de cellule unique |
| US11111489B1 (en) | 2021-01-06 | 2021-09-07 | Think Therapeutics, Inc. | Multiplexed testing of lymphocytes for antigen specificity |
| CN113512767B (zh) * | 2021-04-30 | 2022-09-23 | 天津诺禾致源生物信息科技有限公司 | 用于构建small RNA文库的接头、试剂盒及small RNA文库的构建方法 |
| CN113322523B (zh) * | 2021-06-17 | 2024-03-19 | 翌圣生物科技(上海)股份有限公司 | Rna快速建库方法及其应用 |
| CN113462750B (zh) * | 2021-06-29 | 2024-08-27 | 浙江峻山生物科技有限公司 | 一种提高病毒核酸检测灵敏度的样本保存液及其制备方法 |
| US20240327905A1 (en) * | 2021-07-20 | 2024-10-03 | Donald Danforth Plant Science Center | All-in-one rna sequencing assay and uses thereof |
| WO2023086819A1 (fr) * | 2021-11-09 | 2023-05-19 | Nuprobe Usa, Inc. | Méthodes et compositions de séquençage et de détection de fusion à l'aide d'amorces inverses plus aléatoires |
| WO2023141604A2 (fr) * | 2022-01-21 | 2023-07-27 | Mission Bio, Inc. | Méthodes de marquage moléculaire pour analyse de cellule unique |
| CN116010022B (zh) * | 2022-11-29 | 2026-03-17 | 兴业银行股份有限公司 | Presto自动化伸缩的系统、方法及介质 |
| CN121909286A (zh) * | 2023-07-14 | 2026-04-21 | 布罗德研究所 | 从寡核苷酸池中组装基因文库的方法 |
| CN118280446B (zh) * | 2024-05-31 | 2024-08-13 | 浙江大学 | 植物单细胞非编码基因鉴定和功能预测方法、装置及应用 |
| CN118727162B (zh) * | 2024-06-05 | 2025-04-04 | 首都医科大学附属北京口腔医院 | 单细胞4c文库构建方法和检测方法 |
| WO2026058704A1 (fr) * | 2024-09-10 | 2026-03-19 | 国立大学法人 東京大学 | Procédé de synthèse d'adn simple brin contenant des séquences de code-barres d'adn |
| CN120400136A (zh) * | 2025-07-01 | 2025-08-01 | 杭州华大生命科学研究院 | 模板转换寡核苷酸、试剂盒及其应用 |
Family Cites Families (85)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4656134A (en) | 1982-01-11 | 1987-04-07 | Board Of Trustees Of Leland Stanford Jr. University | Gene amplification in eukaryotic cells |
| US5242794A (en) | 1984-12-13 | 1993-09-07 | Applied Biosystems, Inc. | Detection of specific sequences in nucleic acids |
| US4965188A (en) | 1986-08-22 | 1990-10-23 | Cetus Corporation | Process for amplifying, detecting, and/or cloning nucleic acid sequences using a thermostable enzyme |
| US4683195A (en) | 1986-01-30 | 1987-07-28 | Cetus Corporation | Process for amplifying, detecting, and/or-cloning nucleic acid sequences |
| US4683202A (en) | 1985-03-28 | 1987-07-28 | Cetus Corporation | Process for amplifying nucleic acid sequences |
| US4766067A (en) | 1985-05-31 | 1988-08-23 | President And Fellows Of Harvard College | Gene amplification |
| GB8601597D0 (en) | 1986-01-23 | 1986-02-26 | Wilson R H | Nucleotide sequences |
| US4800159A (en) | 1986-02-07 | 1989-01-24 | Cetus Corporation | Process for amplifying, detecting, and/or cloning nucleic acid sequences |
| US4889818A (en) | 1986-08-22 | 1989-12-26 | Cetus Corporation | Purified thermostable enzyme |
| US4921794A (en) | 1987-01-14 | 1990-05-01 | President And Fellows Of Harvard College | T7 DNA polymerase |
| US4795699A (en) | 1987-01-14 | 1989-01-03 | President And Fellows Of Harvard College | T7 DNA polymerase |
| US4988617A (en) | 1988-03-25 | 1991-01-29 | California Institute Of Technology | Method of detecting a nucleotide change in nucleic acids |
| US5168038A (en) | 1988-06-17 | 1992-12-01 | The Board Of Trustees Of The Leland Stanford Junior University | In situ transcription in cells and tissues |
| US5130238A (en) | 1988-06-24 | 1992-07-14 | Cangene Corporation | Enhanced nucleic acid amplification process |
| US5066584A (en) | 1988-09-23 | 1991-11-19 | Cetus Corporation | Methods for generating single stranded dna by the polymerase chain reaction |
| US5142033A (en) | 1988-09-23 | 1992-08-25 | Hoffmann-La Roche Inc. | Structure-independent DNA amplification by the polymerase chain reaction |
| US5091310A (en) | 1988-09-23 | 1992-02-25 | Cetus Corporation | Structure-independent dna amplification by the polymerase chain reaction |
| US4994370A (en) | 1989-01-03 | 1991-02-19 | The United States Of America As Represented By The Department Of Health And Human Services | DNA amplification technique |
| DE3920358A1 (de) | 1989-06-22 | 1991-01-17 | Behringwerke Ag | Bispezifische und oligospezifische, mono- und oligovalente antikoerperkonstrukte, ihre herstellung und verwendung |
| US5494810A (en) | 1990-05-03 | 1996-02-27 | Cornell Research Foundation, Inc. | Thermostable ligase-mediated DNA amplifications system for the detection of genetic disease |
| US5210015A (en) | 1990-08-06 | 1993-05-11 | Hoffman-La Roche Inc. | Homogeneous assay system using the nuclease activity of a nucleic acid polymerase |
| DE69232137T2 (de) | 1991-11-25 | 2002-05-29 | Enzon Inc | Multivalente antigen-bindende proteine |
| CA2124967C (fr) | 1991-12-17 | 2008-04-08 | Nils Lonberg | Animaux transgeniques non humains capables de produire des anticorps heterologues |
| US5925517A (en) | 1993-11-12 | 1999-07-20 | The Public Health Research Institute Of The City Of New York, Inc. | Detectably labeled dual conformation oligonucleotide probes, assays and kits |
| US5750341A (en) | 1995-04-17 | 1998-05-12 | Lynx Therapeutics, Inc. | DNA sequencing by parallel oligonucleotide extensions |
| US6852487B1 (en) | 1996-02-09 | 2005-02-08 | Cornell Research Foundation, Inc. | Detection of nucleic acid sequence differences using the ligase detection reaction with addressable arrays |
| EP1736554B1 (fr) | 1996-05-29 | 2013-10-09 | Cornell Research Foundation, Inc. | Detection de differences dans des sequences d'acides nucleiques utilisant une combinaison de la detection par ligase et de reactions d'amplification en chaine par polymerase |
| EP1033411B1 (fr) | 1996-06-04 | 2006-02-22 | University of Utah Research Foundation | Paire fluorescente donneur-accepteur |
| US6054276A (en) | 1998-02-23 | 2000-04-25 | Macevicz; Stephen C. | DNA restriction site mapping |
| AU3463699A (en) | 1998-04-03 | 1999-10-25 | Phylos, Inc. | Addressable protein arrays |
| US6780591B2 (en) | 1998-05-01 | 2004-08-24 | Arizona Board Of Regents | Method of determining the nucleotide sequence of oligonucleotides and DNA molecules |
| JP3813818B2 (ja) | 1998-05-01 | 2006-08-23 | アリゾナ ボード オブ リージェンツ | オリゴヌクレオチドおよびｄｎａ分子のヌクレオチド配列の決定方法 |
| US6787308B2 (en) | 1998-07-30 | 2004-09-07 | Solexa Ltd. | Arrayed biomolecules and their use in sequencing |
| GB9928787D0 (en) | 1999-12-03 | 2000-02-02 | Medical Res Council | Direct screening method |
| US6582938B1 (en) | 2001-05-11 | 2003-06-24 | Affymetrix, Inc. | Amplification of nucleic acids |
| US6686184B1 (en) | 2000-05-25 | 2004-02-03 | President And Fellows Of Harvard College | Patterning of surfaces utilizing microfluidic stamps including three-dimensionally arrayed channel networks |
| AU2002321581C1 (en) | 2001-08-31 | 2008-09-18 | Adaptimmune Limited | Soluble T cell receptor |
| GB0127564D0 (en) | 2001-11-16 | 2002-01-09 | Medical Res Council | Emulsion compositions |
| JP2006507921A (ja) | 2002-06-28 | 2006-03-09 | プレジデント・アンド・フェロウズ・オブ・ハーバード・カレッジ | 流体分散のための方法および装置 |
| AU2003271904B2 (en) | 2002-10-09 | 2009-03-05 | Adaptimmune Limited | Single chain recombinant T cell receptors |
| US20060078893A1 (en) | 2004-10-12 | 2006-04-13 | Medical Research Council | Compartmentalised combinatorial chemistry by microfluidic control |
| EP2127736A1 (fr) | 2003-04-10 | 2009-12-02 | The President and Fellows of Harvard College | Formation et régulation d'espèces fluidiques |
| CN104069784B (zh) | 2003-08-27 | 2017-01-11 | 哈佛大学 | 流体物种的电子控制 |
| US7169560B2 (en) | 2003-11-12 | 2007-01-30 | Helicos Biosciences Corporation | Short cycle methods for sequencing polynucleotides |
| US20050221339A1 (en) | 2004-03-31 | 2005-10-06 | Medical Research Council Harvard University | Compartmentalised screening by microfluidic control |
| US7643818B2 (en) | 2004-11-22 | 2010-01-05 | Seven Networks, Inc. | E-mail messaging to/from a mobile terminal |
| EP2248578B1 (fr) | 2005-03-04 | 2012-06-06 | President and Fellows of Harvard College | Procédé pour former des émulsions multiples |
| JP2009536313A (ja) | 2006-01-11 | 2009-10-08 | レインダンス テクノロジーズ， インコーポレイテッド | ナノリアクターの形成および制御において使用するマイクロ流体デバイスおよび方法 |
| WO2007089541A2 (fr) | 2006-01-27 | 2007-08-09 | President And Fellows Of Harvard College | Coalescence de gouttelettes fluidiques |
| ATE540750T1 (de) | 2006-05-11 | 2012-01-15 | Raindance Technologies Inc | Mikrofluidische vorrichtung und verfahren |
| US8911948B2 (en) | 2008-04-30 | 2014-12-16 | Integrated Dna Technologies, Inc. | RNase H-based assays utilizing modified RNA monomers |
| DK2279263T3 (da) | 2008-04-30 | 2013-11-11 | Integrated Dna Tech Inc | Rnase-h-baserede assays med anvendelse af modificerede rna-monomerer |
| CA2738578C (fr) | 2008-09-23 | 2021-05-04 | Quantalife, Inc. | Systeme de dosage base sur des gouttelettes |
| DK3002337T3 (en) | 2009-03-30 | 2019-02-18 | Illumina Inc | ANALYSIS OF EXPRESSION OF GENES IN SINGLE CELLS |
| CA2777053A1 (fr) | 2009-10-06 | 2011-04-14 | The Board Of Trustees Of The University Of Illinois | Recepteurs de lymphocytes t a chaine unique humains |
| EP2625320B1 (fr) | 2010-10-08 | 2019-03-27 | President and Fellows of Harvard College | Établissement à haut débit d'un code-barres de cellules simples |
| EP2625295B1 (fr) | 2010-10-08 | 2019-03-13 | President and Fellows of Harvard College | Séquençage immunitaire à haut débit |
| WO2013033271A2 (fr) | 2011-08-29 | 2013-03-07 | Derren Barken | Méthode permettant d'améliorer le système immunitaire en réaction à une maladie ou une lésion |
| US20140378349A1 (en) * | 2012-08-14 | 2014-12-25 | 10X Technologies, Inc. | Compositions and methods for sample processing |
| WO2014108850A2 (fr) * | 2013-01-09 | 2014-07-17 | Yeda Research And Development Co. Ltd. | Analyse de transcriptome à haut débit |
| US10119134B2 (en) | 2013-03-15 | 2018-11-06 | Abvitro Llc | Single cell bar-coding for antibody discovery |
| RU2578009C2 (ru) * | 2013-05-08 | 2016-03-20 | Закрытое акционерное общество "ЕВРОГЕН" | Способ идентификации нативных пар фрагментов днк или рнк, присутствующих в одних и тех же живых клетках |
| BR112015032512A8 (pt) * | 2013-06-27 | 2020-01-07 | 10X Genomics Inc | método de implementação de código de barras de materiais de amostra |
| GB201317301D0 (en) | 2013-09-30 | 2013-11-13 | Linnarsson Sten | Method for capturing and encoding nucleic acid from a plurality of single cells |
| US10208338B2 (en) * | 2014-03-03 | 2019-02-19 | Swift Biosciences, Inc. | Enhanced adaptor ligation |
| WO2015164212A1 (fr) | 2014-04-21 | 2015-10-29 | President And Fellows Of Harvard College | Systèmes et procédés permettant de marquer des acides nucléiques avec un code à barres |
| CN113249435B (zh) | 2014-06-26 | 2024-09-03 | 10X基因组学有限公司 | 分析来自单个细胞或细胞群体的核酸的方法 |
| CN107873054B (zh) | 2014-09-09 | 2022-07-12 | 博德研究所 | 用于复合单细胞核酸分析的基于微滴的方法和设备 |
| ES2895750T3 (es) * | 2014-09-15 | 2022-02-22 | Abvitro Llc | Secuenciación de alto rendimiento de colecciones de nucleótidos |
| US10993997B2 (en) | 2014-12-19 | 2021-05-04 | The Broad Institute, Inc. | Methods for profiling the t cell repertoire |
| CN115011670A (zh) * | 2015-02-04 | 2022-09-06 | 加利福尼亚大学董事会 | 通过在离散实体中条形码化对核酸进行测序 |
| WO2016168584A1 (fr) | 2015-04-17 | 2016-10-20 | President And Fellows Of Harvard College | Systèmes de codes barres et procédés de séquençage de gènes et autres applications |
| AU2016253964B2 (en) | 2015-04-27 | 2022-07-07 | Abvitro Llc | Methods of sequencing, determining, pairing, and validating therapeutic agents and disease specific antigens |
| AU2016326738B2 (en) | 2015-09-24 | 2023-08-31 | Abvitro Llc | HIV antibody compositions and methods of use |
| KR20180085717A (ko) * | 2015-09-24 | 2018-07-27 | 에이비비트로, 엘엘씨 | 친화성-올리고뉴클레오타이드 콘쥬게이트 및 그것의 사용 |
| WO2017053903A1 (fr) | 2015-09-24 | 2017-03-30 | Abvitro Llc | Acp par exclusion activée à produit d'amplification unique |
| JP7341661B2 (ja) | 2015-09-25 | 2023-09-11 | アブビトロ， エルエルシー | ネイティブに対合するｔ細胞受容体配列のｔ細胞受容体標的識別のための高スループットプロセス |
| BR112019005748A2 (pt) | 2016-09-24 | 2019-06-18 | Abvitro Llc | afinidade-conjugados de oligonucleotídeo e usos destes |
| WO2018083849A1 (fr) | 2016-11-02 | 2018-05-11 | 三菱電機株式会社 | Appareil de traitement d'eau et procédé de traitement d'eau |
| US20200078404A1 (en) | 2017-05-01 | 2020-03-12 | Juno Therapeutics, Inc. | Combination of a cell therapy and an immunomodulatory compound |
| ES2926722T3 (es) | 2017-05-26 | 2022-10-27 | Abvitro Llc | Secuenciación de alto rendimiento de biblioteca de polinucleótidos y análisis de transcriptoma |
| CN111263641B (zh) | 2017-08-09 | 2025-10-31 | 朱诺治疗学股份有限公司 | 用于制备基因工程化细胞的方法和组合物 |
| US20190064173A1 (en) | 2017-08-22 | 2019-02-28 | 10X Genomics, Inc. | Methods of producing droplets including a particle and an analyte |
| EP3679370A1 (fr) | 2017-09-07 | 2020-07-15 | Juno Therapeutics, Inc. | Procédés d'identification de caractéristiques cellulaires relatives à des réponses associées à une thérapie cellulaire |
| US11851679B2 (en) | 2017-11-01 | 2023-12-26 | Juno Therapeutics, Inc. | Method of assessing activity of recombinant antigen receptors |
-
2018
- 2018-05-25 ES ES18731697T patent/ES2926722T3/es active Active
- 2018-05-25 AU AU2018273999A patent/AU2018273999A1/en not_active Abandoned
- 2018-05-25 US US16/616,424 patent/US12049667B2/en active Active
- 2018-05-25 CA CA3064205A patent/CA3064205A1/fr active Pending
- 2018-05-25 KR KR1020197038441A patent/KR102550778B1/ko active Active
- 2018-05-25 MA MA049352A patent/MA49352A/fr unknown
- 2018-05-25 EP EP18731697.1A patent/EP3631012B1/fr active Active
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- 2018-05-25 JP JP2020515835A patent/JP7308187B2/ja active Active
- 2018-05-25 WO PCT/US2018/034768 patent/WO2018218222A1/fr not_active Ceased
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| Publication number | Publication date |
|---|---|
| EP3631012A1 (fr) | 2020-04-08 |
| RU2019143662A (ru) | 2021-06-28 |
| JP7308187B2 (ja) | 2023-07-13 |
| CA3064205A1 (fr) | 2018-11-29 |
| KR20200039623A (ko) | 2020-04-16 |
| AU2018273999A1 (en) | 2019-12-05 |
| CN111148849A (zh) | 2020-05-12 |
| ES2926722T3 (es) | 2022-10-27 |
| EP3631012B1 (fr) | 2022-06-08 |
| US20200354784A1 (en) | 2020-11-12 |
| KR102550778B1 (ko) | 2023-07-03 |
| US12049667B2 (en) | 2024-07-30 |
| JP2020523034A (ja) | 2020-08-06 |
| WO2018218222A1 (fr) | 2018-11-29 |
| RU2019143662A3 (fr) | 2022-02-25 |
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