MA49352A - Séquençage de bibliothèque de polynucléotides à haut rendement et analyse de transcriptome - Google Patents
Séquençage de bibliothèque de polynucléotides à haut rendement et analyse de transcriptomeInfo
- Publication number
- MA49352A MA49352A MA049352A MA49352A MA49352A MA 49352 A MA49352 A MA 49352A MA 049352 A MA049352 A MA 049352A MA 49352 A MA49352 A MA 49352A MA 49352 A MA49352 A MA 49352A
- Authority
- MA
- Morocco
- Prior art keywords
- high yield
- transcriptome analysis
- polynucleotide library
- library sequencing
- yield polynucleotide
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
- C12Q1/6853—Nucleic acid amplification reactions using modified primers or templates
- C12Q1/6855—Ligating adaptors
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2525/00—Reactions involving modified oligonucleotides, nucleic acids, or nucleotides
- C12Q2525/10—Modifications characterised by
- C12Q2525/155—Modifications characterised by incorporating/generating a new priming site
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2525/00—Reactions involving modified oligonucleotides, nucleic acids, or nucleotides
- C12Q2525/10—Modifications characterised by
- C12Q2525/179—Modifications characterised by incorporating arbitrary or random nucleotide sequences
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2525/00—Reactions involving modified oligonucleotides, nucleic acids, or nucleotides
- C12Q2525/10—Modifications characterised by
- C12Q2525/191—Modifications characterised by incorporating an adaptor
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2563/00—Nucleic acid detection characterized by the use of physical, structural and functional properties
- C12Q2563/159—Microreactors, e.g. emulsion PCR or sequencing, droplet PCR, microcapsules, i.e. non-liquid containers with a range of different permeability's for different reaction components
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2563/00—Nucleic acid detection characterized by the use of physical, structural and functional properties
- C12Q2563/179—Nucleic acid detection characterized by the use of physical, structural and functional properties the label being a nucleic acid
-
- C—CHEMISTRY; METALLURGY
- C40—COMBINATORIAL TECHNOLOGY
- C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
- C40B40/00—Libraries per se, e.g. arrays, mixtures
- C40B40/04—Libraries containing only organic compounds
- C40B40/06—Libraries containing nucleotides or polynucleotides, or derivatives thereof
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Biotechnology (AREA)
- Analytical Chemistry (AREA)
- Physics & Mathematics (AREA)
- Microbiology (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762511949P | 2017-05-26 | 2017-05-26 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MA49352A true MA49352A (fr) | 2020-04-08 |
Family
ID=62621068
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MA049352A MA49352A (fr) | 2017-05-26 | 2018-05-25 | Séquençage de bibliothèque de polynucléotides à haut rendement et analyse de transcriptome |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US20200354784A1 (fr) |
| EP (1) | EP3631012B1 (fr) |
| JP (1) | JP7308187B2 (fr) |
| KR (1) | KR102550778B1 (fr) |
| CN (1) | CN111148849A (fr) |
| AU (1) | AU2018273999A1 (fr) |
| CA (1) | CA3064205A1 (fr) |
| ES (1) | ES2926722T3 (fr) |
| MA (1) | MA49352A (fr) |
| WO (1) | WO2018218222A1 (fr) |
Families Citing this family (38)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8835358B2 (en) | 2009-12-15 | 2014-09-16 | Cellular Research, Inc. | Digital counting of individual molecules by stochastic attachment of diverse labels |
| ES2904816T3 (es) | 2012-02-27 | 2022-04-06 | Becton Dickinson Co | Composiciones para recuento molecular |
| GB2546833B (en) | 2013-08-28 | 2018-04-18 | Cellular Res Inc | Microwell for single cell analysis comprising single cell and single bead oligonucleotide capture labels |
| WO2016138496A1 (fr) | 2015-02-27 | 2016-09-01 | Cellular Research, Inc. | Codage à barres moléculaire à adressage spatial |
| ES2934982T3 (es) | 2015-03-30 | 2023-02-28 | Becton Dickinson Co | Métodos para la codificación con códigos de barras combinatorios |
| WO2017044574A1 (fr) | 2015-09-11 | 2017-03-16 | Cellular Research, Inc. | Procédés et compositions pour la normalisation de banques d'acides nucléiques |
| US10301677B2 (en) | 2016-05-25 | 2019-05-28 | Cellular Research, Inc. | Normalization of nucleic acid libraries |
| US10640763B2 (en) | 2016-05-31 | 2020-05-05 | Cellular Research, Inc. | Molecular indexing of internal sequences |
| US10202641B2 (en) | 2016-05-31 | 2019-02-12 | Cellular Research, Inc. | Error correction in amplification of samples |
| AU2017331459B2 (en) | 2016-09-26 | 2023-04-13 | Becton, Dickinson And Company | Measurement of protein expression using reagents with barcoded oligonucleotide sequences |
| US11319583B2 (en) | 2017-02-01 | 2022-05-03 | Becton, Dickinson And Company | Selective amplification using blocking oligonucleotides |
| US11773441B2 (en) | 2018-05-03 | 2023-10-03 | Becton, Dickinson And Company | High throughput multiomics sample analysis |
| US11365409B2 (en) | 2018-05-03 | 2022-06-21 | Becton, Dickinson And Company | Molecular barcoding on opposite transcript ends |
| JP2022511398A (ja) | 2018-10-01 | 2022-01-31 | ベクトン・ディキンソン・アンド・カンパニー | ５’転写物配列の決定 |
| EP3877520A1 (fr) | 2018-11-08 | 2021-09-15 | Becton Dickinson and Company | Analyse transcriptomique complète de cellules uniques à l'aide d'un amorçage aléatoire |
| CN113195717A (zh) | 2018-12-13 | 2021-07-30 | 贝克顿迪金森公司 | 单细胞全转录组分析中的选择性延伸 |
| US20220112539A1 (en) * | 2018-12-28 | 2022-04-14 | National University Of Singapore | Methods For Targeted Complementary DNA Enrichment |
| WO2020154247A1 (fr) | 2019-01-23 | 2020-07-30 | Cellular Research, Inc. | Oligonucléotides associés à des anticorps |
| US11939622B2 (en) | 2019-07-22 | 2024-03-26 | Becton, Dickinson And Company | Single cell chromatin immunoprecipitation sequencing assay |
| CA3156704A1 (fr) * | 2019-10-09 | 2021-04-15 | Edward Fritsch | Vaccin a proteines multi-domaines |
| CN114729350A (zh) * | 2019-11-08 | 2022-07-08 | 贝克顿迪金森公司 | 使用随机引发获得用于免疫组库测序的全长v(d)j信息 |
| CN115244184A (zh) | 2020-01-13 | 2022-10-25 | 贝克顿迪金森公司 | 用于定量蛋白和rna的方法和组合物 |
| EP4106769A4 (fr) * | 2020-02-17 | 2024-03-27 | Universal Sequencing Tech Corporation | Procédés de codage à barres d'acide nucléique pour la détection et le séquençage |
| US11661625B2 (en) | 2020-05-14 | 2023-05-30 | Becton, Dickinson And Company | Primers for immune repertoire profiling |
| CA3185619A1 (fr) * | 2020-05-29 | 2021-12-02 | Riken | Procede de traitement d'une population cellulaire et procede d'analyse de genes inclus dans une population cellulaire |
| US20210371909A1 (en) * | 2020-06-02 | 2021-12-02 | Becton, Dickinson And Company | Oligonucleotides and beads for 5 prime gene expression assay |
| KR102468839B1 (ko) * | 2020-06-03 | 2022-11-18 | 주식회사 제노헬릭스 | Rna 검출 방법 |
| CN111549025B (zh) * | 2020-06-08 | 2021-09-14 | 郑州大学第一附属医院 | 链置换引物和细胞转录组文库构建方法 |
| US11932901B2 (en) | 2020-07-13 | 2024-03-19 | Becton, Dickinson And Company | Target enrichment using nucleic acid probes for scRNAseq |
| EP4240842A1 (fr) * | 2020-11-03 | 2023-09-13 | ACT Genomics (IP) Limited | Procédé de séquençage ciblé et kit associé pour détecter une altération génétique |
| US11739443B2 (en) | 2020-11-20 | 2023-08-29 | Becton, Dickinson And Company | Profiling of highly expressed and lowly expressed proteins |
| US20220177950A1 (en) * | 2020-12-03 | 2022-06-09 | Roche Sequencing Solutions, Inc. | Whole transcriptome analysis in single cells |
| CN113512767B (zh) * | 2021-04-30 | 2022-09-23 | 天津诺禾致源生物信息科技有限公司 | 用于构建small RNA文库的接头、试剂盒及small RNA文库的构建方法 |
| CN113322523B (zh) * | 2021-06-17 | 2024-03-19 | 翌圣生物科技(上海)股份有限公司 | Rna快速建库方法及其应用 |
| CN113462750A (zh) * | 2021-06-29 | 2021-10-01 | 浙江峻山生物科技有限公司 | 一种提高病毒核酸检测灵敏度的样本保存液及其制备方法 |
| CA3225604A1 (fr) * | 2021-07-20 | 2023-01-26 | R. Keith SLOTKIN | Dosage de sequencage d'arn tout-en-un et ses utilisations |
| WO2023086819A1 (fr) * | 2021-11-09 | 2023-05-19 | Nuprobe Usa, Inc. | Méthodes et compositions de séquençage et de détection de fusion à l'aide d'amorces inverses plus aléatoires |
| WO2023141604A2 (fr) * | 2022-01-21 | 2023-07-27 | Mission Bio, Inc. | Méthodes de marquage moléculaire pour analyse de cellule unique |
Family Cites Families (70)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4656134A (en) | 1982-01-11 | 1987-04-07 | Board Of Trustees Of Leland Stanford Jr. University | Gene amplification in eukaryotic cells |
| US5242794A (en) | 1984-12-13 | 1993-09-07 | Applied Biosystems, Inc. | Detection of specific sequences in nucleic acids |
| US4683195A (en) | 1986-01-30 | 1987-07-28 | Cetus Corporation | Process for amplifying, detecting, and/or-cloning nucleic acid sequences |
| US4683202A (en) | 1985-03-28 | 1987-07-28 | Cetus Corporation | Process for amplifying nucleic acid sequences |
| US4965188A (en) | 1986-08-22 | 1990-10-23 | Cetus Corporation | Process for amplifying, detecting, and/or cloning nucleic acid sequences using a thermostable enzyme |
| US4766067A (en) | 1985-05-31 | 1988-08-23 | President And Fellows Of Harvard College | Gene amplification |
| GB8601597D0 (en) | 1986-01-23 | 1986-02-26 | Wilson R H | Nucleotide sequences |
| US4800159A (en) | 1986-02-07 | 1989-01-24 | Cetus Corporation | Process for amplifying, detecting, and/or cloning nucleic acid sequences |
| US4889818A (en) | 1986-08-22 | 1989-12-26 | Cetus Corporation | Purified thermostable enzyme |
| US4795699A (en) | 1987-01-14 | 1989-01-03 | President And Fellows Of Harvard College | T7 DNA polymerase |
| US4921794A (en) | 1987-01-14 | 1990-05-01 | President And Fellows Of Harvard College | T7 DNA polymerase |
| US4988617A (en) | 1988-03-25 | 1991-01-29 | California Institute Of Technology | Method of detecting a nucleotide change in nucleic acids |
| US5168038A (en) | 1988-06-17 | 1992-12-01 | The Board Of Trustees Of The Leland Stanford Junior University | In situ transcription in cells and tissues |
| US5130238A (en) | 1988-06-24 | 1992-07-14 | Cangene Corporation | Enhanced nucleic acid amplification process |
| US5066584A (en) | 1988-09-23 | 1991-11-19 | Cetus Corporation | Methods for generating single stranded dna by the polymerase chain reaction |
| US5142033A (en) | 1988-09-23 | 1992-08-25 | Hoffmann-La Roche Inc. | Structure-independent DNA amplification by the polymerase chain reaction |
| US5091310A (en) | 1988-09-23 | 1992-02-25 | Cetus Corporation | Structure-independent dna amplification by the polymerase chain reaction |
| US4994370A (en) | 1989-01-03 | 1991-02-19 | The United States Of America As Represented By The Department Of Health And Human Services | DNA amplification technique |
| DE3920358A1 (de) | 1989-06-22 | 1991-01-17 | Behringwerke Ag | Bispezifische und oligospezifische, mono- und oligovalente antikoerperkonstrukte, ihre herstellung und verwendung |
| US5494810A (en) | 1990-05-03 | 1996-02-27 | Cornell Research Foundation, Inc. | Thermostable ligase-mediated DNA amplifications system for the detection of genetic disease |
| US5210015A (en) | 1990-08-06 | 1993-05-11 | Hoffman-La Roche Inc. | Homogeneous assay system using the nuclease activity of a nucleic acid polymerase |
| EP0617706B1 (fr) | 1991-11-25 | 2001-10-17 | Enzon, Inc. | Proteines multivalentes de fixation aux antigenes |
| EP0746609A4 (fr) | 1991-12-17 | 1997-12-17 | Genpharm Int | Animaux transgeniques non humains capables de produire des anticorps heterologues |
| US5925517A (en) | 1993-11-12 | 1999-07-20 | The Public Health Research Institute Of The City Of New York, Inc. | Detectably labeled dual conformation oligonucleotide probes, assays and kits |
| US5750341A (en) | 1995-04-17 | 1998-05-12 | Lynx Therapeutics, Inc. | DNA sequencing by parallel oligonucleotide extensions |
| US6852487B1 (en) | 1996-02-09 | 2005-02-08 | Cornell Research Foundation, Inc. | Detection of nucleic acid sequence differences using the ligase detection reaction with addressable arrays |
| CA2255774C (fr) | 1996-05-29 | 2008-03-18 | Cornell Research Foundation, Inc. | Detection de differences dans des sequences d'acides nucleiques utilisant une combinaison de la detection par ligase et de reactions d'amplification en chaine par polymerase |
| CA2257109C (fr) | 1996-06-04 | 2009-10-06 | University Of Utah Research Foundation | Controle de l'hybridation pendant la pcr |
| US6054276A (en) | 1998-02-23 | 2000-04-25 | Macevicz; Stephen C. | DNA restriction site mapping |
| ATE340870T1 (de) | 1998-04-03 | 2006-10-15 | Compound Therapeutics Inc | Adressierbare protein arrays |
| US6780591B2 (en) | 1998-05-01 | 2004-08-24 | Arizona Board Of Regents | Method of determining the nucleotide sequence of oligonucleotides and DNA molecules |
| WO1999057321A1 (fr) | 1998-05-01 | 1999-11-11 | Arizona Board Of Regents | Procede de determination de la sequence nucleotidique d'oligonucleotides et de molecules d'adn |
| US6787308B2 (en) | 1998-07-30 | 2004-09-07 | Solexa Ltd. | Arrayed biomolecules and their use in sequencing |
| GB9928787D0 (en) | 1999-12-03 | 2000-02-02 | Medical Res Council | Direct screening method |
| US6582938B1 (en) | 2001-05-11 | 2003-06-24 | Affymetrix, Inc. | Amplification of nucleic acids |
| US6686184B1 (en) | 2000-05-25 | 2004-02-03 | President And Fellows Of Harvard College | Patterning of surfaces utilizing microfluidic stamps including three-dimensionally arrayed channel networks |
| ES2239246T3 (es) | 2001-08-31 | 2005-09-16 | Avidex Limited | Receptor soluble de celulas t. |
| GB0127564D0 (en) | 2001-11-16 | 2002-01-09 | Medical Res Council | Emulsion compositions |
| JP2006507921A (ja) | 2002-06-28 | 2006-03-09 | プレジデント・アンド・フェロウズ・オブ・ハーバード・カレッジ | 流体分散のための方法および装置 |
| NZ539225A (en) | 2002-10-09 | 2006-09-29 | Avidex Ltd | Single chain recombinant T cell receptors |
| US20060078893A1 (en) | 2004-10-12 | 2006-04-13 | Medical Research Council | Compartmentalised combinatorial chemistry by microfluidic control |
| CA2521862C (fr) | 2003-04-10 | 2012-10-16 | President And Fellows Of Harvard College | Formation et regulation d'especes fluidiques |
| EP2662136A3 (fr) | 2003-08-27 | 2013-12-25 | President and Fellows of Harvard College | Méthode de manipulation et de mélange de gouttelettes |
| US7169560B2 (en) | 2003-11-12 | 2007-01-30 | Helicos Biosciences Corporation | Short cycle methods for sequencing polynucleotides |
| US20050221339A1 (en) | 2004-03-31 | 2005-10-06 | Medical Research Council Harvard University | Compartmentalised screening by microfluidic control |
| US7643818B2 (en) | 2004-11-22 | 2010-01-05 | Seven Networks, Inc. | E-mail messaging to/from a mobile terminal |
| US9039273B2 (en) | 2005-03-04 | 2015-05-26 | President And Fellows Of Harvard College | Method and apparatus for forming multiple emulsions |
| EP1984738A2 (fr) | 2006-01-11 | 2008-10-29 | Raindance Technologies, Inc. | Dispositifs microfluidiques et leurs procédés d'utilisation dans la formation et le contrôle de nanoréacteurs |
| ATE484335T1 (de) | 2006-01-27 | 2010-10-15 | Harvard College | Koaleszenz fluider tröpfchen |
| EP2530167A1 (fr) | 2006-05-11 | 2012-12-05 | Raindance Technologies, Inc. | Dispositifs microfluidiques |
| US8911948B2 (en) | 2008-04-30 | 2014-12-16 | Integrated Dna Technologies, Inc. | RNase H-based assays utilizing modified RNA monomers |
| EP3150727B1 (fr) | 2008-04-30 | 2019-07-10 | Integrated DNA Technologies Inc. | Dosages à base de rnase-h utilisant des monomères d'arn modifiés |
| EP2347245B1 (fr) | 2008-09-23 | 2021-11-03 | Bio-Rad Laboratories, Inc. | Procédure d'essai à base des gouttes |
| CA2777053A1 (fr) | 2009-10-06 | 2011-04-14 | The Board Of Trustees Of The University Of Illinois | Recepteurs de lymphocytes t a chaine unique humains |
| ES2731460T3 (es) | 2010-10-08 | 2019-11-15 | Harvard College | Alto rendimiento de células individuales con código de barra |
| WO2014108850A2 (fr) * | 2013-01-09 | 2014-07-17 | Yeda Research And Development Co. Ltd. | Analyse de transcriptome à haut débit |
| US9816088B2 (en) | 2013-03-15 | 2017-11-14 | Abvitro Llc | Single cell bar-coding for antibody discovery |
| RU2578009C2 (ru) * | 2013-05-08 | 2016-03-20 | Закрытое акционерное общество "ЕВРОГЕН" | Способ идентификации нативных пар фрагментов днк или рнк, присутствующих в одних и тех же живых клетках |
| EP3013957B2 (fr) * | 2013-06-27 | 2022-05-11 | 10X Genomics, Inc. | Compositions et procédés de traitement d'échantillon |
| GB201317301D0 (en) * | 2013-09-30 | 2013-11-13 | Linnarsson Sten | Method for capturing and encoding nucleic acid from a plurality of single cells |
| CN107075543B (zh) | 2014-04-21 | 2021-11-16 | 哈佛学院院长及董事 | 用于条形码化核酸的系统和方法 |
| EP4053292A1 (fr) | 2014-06-26 | 2022-09-07 | 10X Genomics, Inc. | Procédés d'analyse d'acides nucléiques provenant de cellules individuelles ou de populations de cellules |
| JP2017532024A (ja) | 2014-09-09 | 2017-11-02 | ザ・ブロード・インスティテュート・インコーポレイテッド | コンポジット単一細胞核酸分析のための液滴ベースの方法および機器 |
| CA2961210A1 (fr) | 2014-09-15 | 2016-03-24 | Abvitro, Inc. | Sequencage a haut debit de banque de nucleotides |
| US10993997B2 (en) | 2014-12-19 | 2021-05-04 | The Broad Institute, Inc. | Methods for profiling the t cell repertoire |
| US11111519B2 (en) | 2015-02-04 | 2021-09-07 | The Regents Of The University Of California | Sequencing of nucleic acids via barcoding in discrete entities |
| WO2016168584A1 (fr) | 2015-04-17 | 2016-10-20 | President And Fellows Of Harvard College | Systèmes de codes barres et procédés de séquençage de gènes et autres applications |
| US10982258B2 (en) | 2015-04-27 | 2021-04-20 | Abvitro Llc | Methods of sequencing, determining, pairing, and validating therapeutic agents and disease specific antigens |
| EP3933047A1 (fr) | 2015-09-24 | 2022-01-05 | AbVitro LLC | Conjugés affinité-oligonucléotide et leurs utilisations |
| CN113774495A (zh) | 2015-09-25 | 2021-12-10 | 阿布维特罗有限责任公司 | 用于对天然配对t细胞受体序列进行t细胞受体靶向鉴别的高通量方法 |
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2018
- 2018-05-25 AU AU2018273999A patent/AU2018273999A1/en active Pending
- 2018-05-25 WO PCT/US2018/034768 patent/WO2018218222A1/fr active Application Filing
- 2018-05-25 MA MA049352A patent/MA49352A/fr unknown
- 2018-05-25 EP EP18731697.1A patent/EP3631012B1/fr active Active
- 2018-05-25 KR KR1020197038441A patent/KR102550778B1/ko active IP Right Grant
- 2018-05-25 ES ES18731697T patent/ES2926722T3/es active Active
- 2018-05-25 CN CN201880049800.9A patent/CN111148849A/zh active Pending
- 2018-05-25 JP JP2020515835A patent/JP7308187B2/ja active Active
- 2018-05-25 US US16/616,424 patent/US20200354784A1/en active Pending
- 2018-05-25 CA CA3064205A patent/CA3064205A1/fr active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| ES2926722T3 (es) | 2022-10-27 |
| RU2019143662A (ru) | 2021-06-28 |
| CN111148849A (zh) | 2020-05-12 |
| EP3631012A1 (fr) | 2020-04-08 |
| AU2018273999A1 (en) | 2019-12-05 |
| US20200354784A1 (en) | 2020-11-12 |
| JP7308187B2 (ja) | 2023-07-13 |
| RU2019143662A3 (fr) | 2022-02-25 |
| CA3064205A1 (fr) | 2018-11-29 |
| KR102550778B1 (ko) | 2023-07-03 |
| JP2020523034A (ja) | 2020-08-06 |
| KR20200039623A (ko) | 2020-04-16 |
| WO2018218222A1 (fr) | 2018-11-29 |
| EP3631012B1 (fr) | 2022-06-08 |
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