MA46430B1 - Thérapie combinée d'agonistes de cnp à libération contrôlée - Google Patents
Thérapie combinée d'agonistes de cnp à libération contrôléeInfo
- Publication number
- MA46430B1 MA46430B1 MA46430A MA46430A MA46430B1 MA 46430 B1 MA46430 B1 MA 46430B1 MA 46430 A MA46430 A MA 46430A MA 46430 A MA46430 A MA 46430A MA 46430 B1 MA46430 B1 MA 46430B1
- Authority
- MA
- Morocco
- Prior art keywords
- controlled
- combination therapy
- treatment
- release cnp
- growth
- Prior art date
Links
- 239000000556 agonist Substances 0.000 title abstract 4
- 238000013270 controlled release Methods 0.000 title abstract 2
- 238000002648 combination therapy Methods 0.000 title 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 3
- 208000035475 disorder Diseases 0.000 abstract 3
- 239000003814 drug Substances 0.000 abstract 3
- 239000008194 pharmaceutical composition Substances 0.000 abstract 3
- 229940079593 drug Drugs 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 230000002265 prevention Effects 0.000 abstract 2
- 239000012634 fragment Substances 0.000 abstract 1
- 230000017363 positive regulation of growth Effects 0.000 abstract 1
- 230000000638 stimulation Effects 0.000 abstract 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/2242—Atrial natriuretic factor complex: Atriopeptins, atrial natriuretic protein [ANP]; Cardionatrin, Cardiodilatin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/27—Growth hormone [GH], i.e. somatotropin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
- A61K47/59—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes
- A61K47/60—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes the organic macromolecular compound being a polyoxyalkylene oligomer, polymer or dendrimer, e.g. PEG, PPG, PEO or polyglycerol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Endocrinology (AREA)
- Immunology (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Physical Education & Sports Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Rheumatology (AREA)
- Molecular Biology (AREA)
- Cardiology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicinal Preparation (AREA)
Abstract
La présente invention porte sur une combinaison d'un agoniste du cnp et d'au moins un autre fragment, ou médicament biologiquement actif, destiné à être utilisé dans un procédé de traitement, ou dans la prévention d'un troubles qui bénéficient de la stimulation de la croissance. Les compositions pharmaceutiques comprennent, au moins, un agoniste du cnp, de préférence un agoniste du cnp à libération contrôlée. La composition pharmaceutique comprend, au moins, une autre fraction, ou un médicament biologiquement actif, pour utiliser ces compositions pharmaceutiques en tant que médicament, pour être utilisé dans le traitement de troubles qui bénéficient de la stimulation de la croissance, et dans des procédés de prévention, ou de traitement d'un patient ayant un trouble qui bénéficie de la stimulation de la croissance.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP16191456 | 2016-09-29 | ||
PCT/EP2017/074596 WO2018060314A1 (fr) | 2016-09-29 | 2017-09-28 | Thérapie combinée d'agonistes de cnp à libération contrôlée |
Publications (2)
Publication Number | Publication Date |
---|---|
MA46430A MA46430A (fr) | 2019-08-07 |
MA46430B1 true MA46430B1 (fr) | 2023-07-31 |
Family
ID=57047055
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MA46430A MA46430B1 (fr) | 2016-09-29 | 2017-09-28 | Thérapie combinée d'agonistes de cnp à libération contrôlée |
Country Status (26)
Country | Link |
---|---|
US (2) | US11564974B2 (fr) |
EP (2) | EP4223309A1 (fr) |
JP (1) | JP7189133B2 (fr) |
KR (2) | KR102531327B1 (fr) |
CN (1) | CN109843295B (fr) |
AU (2) | AU2017336253B2 (fr) |
BR (1) | BR112019005351A2 (fr) |
CA (1) | CA3037448A1 (fr) |
DK (1) | DK3518930T3 (fr) |
ES (1) | ES2943013T3 (fr) |
FI (1) | FI3518930T3 (fr) |
HR (1) | HRP20230385T1 (fr) |
HU (1) | HUE062117T2 (fr) |
IL (3) | IL305975A (fr) |
LT (1) | LT3518930T (fr) |
MA (1) | MA46430B1 (fr) |
MX (1) | MX2019003173A (fr) |
NZ (1) | NZ751746A (fr) |
PL (1) | PL3518930T3 (fr) |
PT (1) | PT3518930T (fr) |
RS (1) | RS64203B1 (fr) |
RU (1) | RU2768747C2 (fr) |
SG (2) | SG10202111952PA (fr) |
SI (1) | SI3518930T1 (fr) |
WO (1) | WO2018060314A1 (fr) |
ZA (1) | ZA201901810B (fr) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2017118707A1 (fr) | 2016-01-08 | 2017-07-13 | Ascendis Pharma Growth Disorders A/S | Agonistes de cnp à libération contrôlée présentant des effets secondaires réduits |
HRP20221339T1 (hr) | 2016-01-08 | 2023-01-06 | Ascendis Pharma Growth Disorders A/S | Cnp predlijekovi s učvršćenjem nosača na cikličkom dijelu peptida |
EP3400021A1 (fr) | 2016-01-08 | 2018-11-14 | Ascendis Pharma Growth Disorders A/S | Agonistes de cnp à libération contrôlée présentant une faible liaison à npr-c |
MX2018008061A (es) * | 2016-01-08 | 2018-08-23 | Ascendis Pharma Growth Disorders As | Profarmacos de peptido natriuretico tipo c (cnp) con porciones portadoras grandes. |
AU2017205693B2 (en) | 2016-01-08 | 2022-03-31 | Ascendis Pharma Growth Disorders A/S | Controlled-release CNP agonists with low initial NPR-B activity |
US20200276276A1 (en) * | 2016-03-01 | 2020-09-03 | Ascendis Pharma Bone Diseases A/S | PTH Prodrugs |
FI3518960T3 (fi) | 2016-09-29 | 2023-10-04 | Ascendis Pharma Bone Diseases As | Annostusohjelma kontrolloidusti vapautuvalle PTH-yhdisteelle |
CA3037448A1 (fr) | 2016-09-29 | 2018-04-05 | Ascendis Pharma Growth Disorders A/S | Therapie combinee d'agonistes de cnp a liberation controlee |
MX2019003182A (es) | 2016-09-29 | 2019-08-05 | Ascendis Pharma Bone Diseases As | Compuestos de hormona paratiroidea con bajas relaciones pico - valle. |
WO2024104922A1 (fr) | 2022-11-14 | 2024-05-23 | Ascendis Pharma Growth Disorders A/S | Procédé d'amélioration de la fonction musculaire squelettique |
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EP3400021A1 (fr) | 2016-01-08 | 2018-11-14 | Ascendis Pharma Growth Disorders A/S | Agonistes de cnp à libération contrôlée présentant une faible liaison à npr-c |
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WO2017118707A1 (fr) | 2016-01-08 | 2017-07-13 | Ascendis Pharma Growth Disorders A/S | Agonistes de cnp à libération contrôlée présentant des effets secondaires réduits |
US20200276276A1 (en) | 2016-03-01 | 2020-09-03 | Ascendis Pharma Bone Diseases A/S | PTH Prodrugs |
CA3037448A1 (fr) | 2016-09-29 | 2018-04-05 | Ascendis Pharma Growth Disorders A/S | Therapie combinee d'agonistes de cnp a liberation controlee |
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2017
- 2017-09-28 CA CA3037448A patent/CA3037448A1/fr active Pending
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- 2017-09-28 KR KR1020197012470A patent/KR102531327B1/ko active IP Right Grant
- 2017-09-28 EP EP17781429.0A patent/EP3518930B1/fr active Active
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- 2017-09-28 RU RU2019112897A patent/RU2768747C2/ru active
- 2017-09-28 KR KR1020237015410A patent/KR20230066147A/ko not_active Application Discontinuation
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2019
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2022
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2023
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