MA44972A - Procédés d'identification de modulateurs du cftr - Google Patents
Procédés d'identification de modulateurs du cftrInfo
- Publication number
- MA44972A MA44972A MA044972A MA44972A MA44972A MA 44972 A MA44972 A MA 44972A MA 044972 A MA044972 A MA 044972A MA 44972 A MA44972 A MA 44972A MA 44972 A MA44972 A MA 44972A
- Authority
- MA
- Morocco
- Prior art keywords
- identification processes
- cftr modulator
- modulator identification
- cftr
- processes
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/502—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/52—Use of compounds or compositions for colorimetric, spectrophotometric or fluorometric investigation, e.g. use of reagent paper and including single- and multilayer analytical elements
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2500/00—Screening for compounds of potential therapeutic value
- G01N2500/02—Screening involving studying the effect of compounds C on the interaction between interacting molecules A and B (e.g. A = enzyme and B = substrate for A, or A = receptor and B = ligand for the receptor)
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2500/00—Screening for compounds of potential therapeutic value
- G01N2500/10—Screening for compounds of potential therapeutic value involving cells
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/38—Pediatrics
- G01N2800/382—Cystic fibrosis
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Chemical & Material Sciences (AREA)
- Urology & Nephrology (AREA)
- Molecular Biology (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Pathology (AREA)
- General Physics & Mathematics (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- General Health & Medical Sciences (AREA)
- Cell Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Toxicology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662333537P | 2016-05-09 | 2016-05-09 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MA44972A true MA44972A (fr) | 2019-03-20 |
Family
ID=58739383
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MA044972A MA44972A (fr) | 2016-05-09 | 2017-05-09 | Procédés d'identification de modulateurs du cftr |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20190154661A1 (fr) |
| EP (1) | EP3455624A1 (fr) |
| AU (1) | AU2017264612A1 (fr) |
| CA (1) | CA3023512A1 (fr) |
| MA (1) | MA44972A (fr) |
| WO (1) | WO2017196843A1 (fr) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2988046A1 (fr) * | 2015-06-02 | 2016-12-08 | Abbvie S.A.R.L. | Pyridines substituees et methode d'utilisation |
| US10548878B2 (en) | 2015-07-24 | 2020-02-04 | Proteostasis Therapeutics, Inc. | Compounds, compositions, and methods of increasing CFTR activity |
| NZ741093A (en) | 2015-10-06 | 2022-12-23 | Proteostasis Therapeutics Inc | Compounds, compositions, and methods for modulating cftr |
| BR112018070747B1 (pt) | 2016-04-07 | 2024-01-09 | Proteostasis Therapeutics, Inc | Átomos de silicone contendo análogos de ivacaftor, composições farmacêuticas e usos terapêuticos |
| AU2017280206A1 (en) | 2016-06-21 | 2019-01-17 | Proteostasis Therapeutics, Inc. | Compounds, compositions, and methods for increasing CFTR activity |
| EP3814336A1 (fr) | 2018-06-27 | 2021-05-05 | Proteostasis Therapeutics, Inc. | Composés améliorant l'activité du protéasome |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2010088630A2 (fr) * | 2009-02-02 | 2010-08-05 | Chromocell Corporation | Lignées cellulaires exprimant cftr et procédés d'utilisation associés |
| HUE026271T2 (en) * | 2010-09-14 | 2016-05-30 | Inst Biochemii I Biofizyki Pan | Mutant CFTR protein modulator compounds and their use for the treatment of diseases that interfere with CFTR protein function disorders |
| MX2015017532A (es) | 2013-06-26 | 2016-10-26 | Proteostasis Therapeutics Inc | Métodos para modular la actividad del regulador de transmembrana de fibrosis quística. |
| US9745292B2 (en) | 2014-03-13 | 2017-08-29 | Proteostasis Therapeutics, Inc. | Compounds, compositions, and methods for increasing CFTR activity |
| EP3116501A1 (fr) | 2014-03-13 | 2017-01-18 | Proteostasis Therapeutics, Inc. | Composés, compositions et procédés pour augmenter l'activité du cftr |
| CA2952862A1 (fr) | 2014-06-19 | 2015-12-23 | Proteostasis Therapeutics, Inc. | Composes, compositions et procedes pour augmenter l'activite du cftr |
| NZ741093A (en) | 2015-10-06 | 2022-12-23 | Proteostasis Therapeutics Inc | Compounds, compositions, and methods for modulating cftr |
-
2017
- 2017-05-09 AU AU2017264612A patent/AU2017264612A1/en not_active Abandoned
- 2017-05-09 EP EP17724705.3A patent/EP3455624A1/fr not_active Withdrawn
- 2017-05-09 MA MA044972A patent/MA44972A/fr unknown
- 2017-05-09 WO PCT/US2017/031754 patent/WO2017196843A1/fr unknown
- 2017-05-09 US US16/300,219 patent/US20190154661A1/en not_active Abandoned
- 2017-05-09 CA CA3023512A patent/CA3023512A1/fr not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| US20190154661A1 (en) | 2019-05-23 |
| WO2017196843A1 (fr) | 2017-11-16 |
| AU2017264612A1 (en) | 2018-11-22 |
| CA3023512A1 (fr) | 2017-11-16 |
| EP3455624A1 (fr) | 2019-03-20 |
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