MA37981A1 - Fibronectin-based scaffold domain proteins that bind to myostatin - Google Patents
Fibronectin-based scaffold domain proteins that bind to myostatinInfo
- Publication number
- MA37981A1 MA37981A1 MA37981A MA37981A MA37981A1 MA 37981 A1 MA37981 A1 MA 37981A1 MA 37981 A MA37981 A MA 37981A MA 37981 A MA37981 A MA 37981A MA 37981 A1 MA37981 A1 MA 37981A1
- Authority
- MA
- Morocco
- Prior art keywords
- proteins
- myostatin
- fibronectin
- bind
- based scaffold
- Prior art date
Links
Abstract
La présente invention concerne des protéines à domaine d'échafaudage à base de fibronectine qui se lient à la myostatine. L'invention concerne également l'utilisation de ces protéines dans des applications thérapeutiques pour traiter la dystrophie musculaire, la cachexie, la sarcopénie, l'arthrose, l'ostéoporose, le diabète, l'obésité, copd, une néphropathie chronique, l'insuffisance cardiaque, un infarctus du myocarde et une fibrose. L'invention concerne en outre des cellules comportant de telles protéines, des polynucléotides codant pour de telles protéines ou leurs fragments, et des vecteurs comportant les polynucléotides codant pour les protéines.The present invention relates to fibronectin-based scaffold domain proteins that bind to myostatin. The invention also relates to the use of these proteins in therapeutic applications for treating muscular dystrophy, cachexia, sarcopenia, osteoarthritis, osteoporosis, diabetes, obesity, copd, chronic nephropathy, heart failure, myocardial infarction and fibrosis. The invention further provides cells comprising such proteins, polynucleotides encoding such proteins or fragments thereof, and vectors comprising the polynucleotides encoding the proteins.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201261700697P | 2012-09-13 | 2012-09-13 | |
PCT/US2013/059458 WO2014043344A1 (en) | 2012-09-13 | 2013-09-12 | Fibronectin based scaffold domain proteins that bind to myostatin |
Publications (2)
Publication Number | Publication Date |
---|---|
MA37981A1 true MA37981A1 (en) | 2017-07-31 |
MA37981B1 MA37981B1 (en) | 2018-09-28 |
Family
ID=56117377
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MA37981A MA37981B1 (en) | 2012-09-13 | 2013-09-12 | Fibronectin-based scaffold domain proteins that bind to myostatin |
Country Status (2)
Country | Link |
---|---|
AR (1) | AR094441A1 (en) |
MA (1) | MA37981B1 (en) |
-
2013
- 2013-09-12 MA MA37981A patent/MA37981B1/en unknown
- 2013-09-12 AR ARP130103275A patent/AR094441A1/en active IP Right Grant
Also Published As
Publication number | Publication date |
---|---|
MA37981B1 (en) | 2018-09-28 |
AR094441A1 (en) | 2015-08-05 |
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