MA32931B1 - Compositions antimicrobiennes - Google Patents

Compositions antimicrobiennes

Info

Publication number
MA32931B1
MA32931B1 MA33932A MA33932A MA32931B1 MA 32931 B1 MA32931 B1 MA 32931B1 MA 33932 A MA33932 A MA 33932A MA 33932 A MA33932 A MA 33932A MA 32931 B1 MA32931 B1 MA 32931B1
Authority
MA
Morocco
Prior art keywords
compositions
antimicrobial compositions
antimicrobial
tolerability
infection
Prior art date
Application number
MA33932A
Other languages
Arabic (ar)
English (en)
Inventor
Danping Li
Eric S Burak
David S Dresback
Danielle Beurer Lord
Original Assignee
Rib X Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=42170697&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MA32931(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Rib X Pharmaceuticals Inc filed Critical Rib X Pharmaceuticals Inc
Publication of MA32931B1 publication Critical patent/MA32931B1/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4709—Non-condensed quinolines and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/40—Cyclodextrins; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
    • A61K47/6949—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes
    • A61K47/6951—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes using cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nanotechnology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Molecular Biology (AREA)
  • Inorganic Chemistry (AREA)
  • Dermatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biotechnology (AREA)
  • Medical Informatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Communicable Diseases (AREA)
  • Organic Chemistry (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Quinoline Compounds (AREA)

Abstract

La présente invention concerne des compositions antimicrobiennes, et plus particulièrement des compositions de dérivés d'acides quinolone-carboxyliques. Ces compositions présentent une solubilité, une stabilité et une tolérabilité améliorées, et sont utiles en administration intraveineuse pour le traitement, la prévention ou la réduction du risque d'infection.
MA33932A 2008-11-15 2009-11-12 Compositions antimicrobiennes MA32931B1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US19925308P 2008-11-15 2008-11-15
PCT/US2009/064220 WO2010056872A2 (fr) 2008-11-15 2009-11-12 Compositions antimicrobiennes

Publications (1)

Publication Number Publication Date
MA32931B1 true MA32931B1 (fr) 2012-01-02

Family

ID=42170697

Family Applications (1)

Application Number Title Priority Date Filing Date
MA33932A MA32931B1 (fr) 2008-11-15 2009-11-12 Compositions antimicrobiennes

Country Status (24)

Country Link
US (5) US20120065186A1 (fr)
EP (1) EP2373166A4 (fr)
JP (3) JP6063123B2 (fr)
KR (1) KR101767689B1 (fr)
CN (3) CN103705942B (fr)
AU (1) AU2009314072C1 (fr)
BR (2) BR122020021551B1 (fr)
CA (1) CA2743419C (fr)
CO (1) CO6382082A2 (fr)
CR (1) CR20110320A (fr)
EA (1) EA025637B1 (fr)
EC (1) ECSP11011119A (fr)
HK (1) HK1213821A1 (fr)
IL (1) IL212781A (fr)
MA (1) MA32931B1 (fr)
MX (1) MX2011005117A (fr)
MY (3) MY194407A (fr)
NI (1) NI201100097A (fr)
NZ (1) NZ593345A (fr)
PE (2) PE20120029A1 (fr)
SV (1) SV2011003907A (fr)
UA (1) UA102709C2 (fr)
WO (1) WO2010056872A2 (fr)
ZA (1) ZA201104108B (fr)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MY194407A (en) * 2008-11-15 2022-11-30 Melinta Subsidiary Corp Antimicrobial Compositions
KR101922752B1 (ko) * 2011-11-29 2018-11-27 주록스 피티와이 리미티드 사이클로덱스트린 및 소수성 약물을 포함하는 주사용 약제학적 조성물을 보존하는 방법
JP6395200B2 (ja) * 2012-10-22 2018-09-26 ジェクス株式会社 ケイ素含有化合物水溶液及び該水溶液を含む抗菌・抗ウィルス剤
CN105189513A (zh) * 2013-03-08 2015-12-23 麦林塔医疗有限公司 葡萄糖醇，1-脱氧-1-(甲胺基)-,1-(6-氨基-3,5-二氟吡啶-2-基)-8-氯-6-氟-1,4-二氢-7-(3-羟基氮杂环丁烷-l-基)-4-氧-3-喹啉羧酸盐的结晶形态
EP2969004A4 (fr) * 2013-03-15 2016-09-21 Melinta Therapeutics Inc Procédés de traitement d'infections chez des patients atteints de surpoids et d'obésité utilisant d'antibiotiques
HUE053654T2 (hu) 2014-03-26 2021-07-28 Astex Therapeutics Ltd FGFR- és CMET-inhibitorok kombinációi a rák kezelésére
TW201605447A (zh) * 2014-06-20 2016-02-16 美林塔治療學有限公司 處理感染的方法
TWI705814B (zh) * 2014-06-20 2020-10-01 美商梅琳塔有限責任公司 醫藥組成物及其用途
CN105693695A (zh) * 2014-11-24 2016-06-22 重庆医药工业研究院有限责任公司 一种德拉沙星葡甲胺盐的晶型及其制备方法
JOP20200201A1 (ar) 2015-02-10 2017-06-16 Astex Therapeutics Ltd تركيبات صيدلانية تشتمل على n-(3.5- ثنائي ميثوكسي فينيل)-n'-(1-ميثيل إيثيل)-n-[3-(ميثيل-1h-بيرازول-4-يل) كينوكسالين-6-يل]إيثان-1.2-ثنائي الأمين
US11324829B2 (en) 2016-03-14 2022-05-10 Santen Pharmaceutical Co., Ltd. Antiseptic agent comprising meglumine or salt thereof
CN107789323B (zh) * 2016-08-31 2021-05-07 鲁南制药集团股份有限公司 一种注射用德拉沙星葡甲胺冻干制剂及其制备方法
CN107789324B (zh) * 2016-08-31 2021-05-25 鲁南制药集团股份有限公司 一种注射用德拉沙星葡甲胺及其制备方法
CN110312511B (zh) * 2017-02-15 2023-10-27 大鹏药品工业株式会社 医药组合物

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US3459731A (en) 1966-12-16 1969-08-05 Corn Products Co Cyclodextrin polyethers and their production
US3426011A (en) 1967-02-13 1969-02-04 Corn Products Co Cyclodextrins with anionic properties
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US5084276A (en) 1990-01-05 1992-01-28 Abbott Laboratories Quinolone carboxylic acid compositions with polymeric additive to reduce vein irritation
KR0166088B1 (ko) * 1990-01-23 1999-01-15 . 수용해도가 증가된 시클로덱스트린 유도체 및 이의 용도
US5376645A (en) 1990-01-23 1994-12-27 University Of Kansas Derivatives of cyclodextrins exhibiting enhanced aqueous solubility and the use thereof
EP0992501B1 (fr) 1995-09-22 2002-08-28 Wakunaga Pharmaceutical Co., Ltd. Dérivés d'acide pyridonecarboxylique en tant qu'agent antibactérien
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US20070049552A1 (en) * 2003-04-14 2007-03-01 Babu Manoj M Fluoroquinolone formulations and methods of making and using the same
EP1789392A2 (fr) 2004-07-30 2007-05-30 Abbott Laboratories Preparation d'antibacteriens a l'acide pyridonecarboxylique
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US20070249577A1 (en) * 2005-05-10 2007-10-25 Hopkins Scott J Method for reducing the risk of or preventing infection due to surgical or invasive medical procedures
CA2611917A1 (fr) * 2005-06-13 2006-12-21 Takeda Pharmaceutical Company Limited Produit d'injection
US20070197469A1 (en) * 2006-02-17 2007-08-23 Murthy Yerramilli V Fluoroquinolone carboxylic acid salt compositions
CN100411688C (zh) * 2006-09-12 2008-08-20 南京师范大学 含有环糊精/多烯紫杉醇包合物的药物组合物及其制备方法
MY194407A (en) * 2008-11-15 2022-11-30 Melinta Subsidiary Corp Antimicrobial Compositions

Also Published As

Publication number Publication date
WO2010056872A3 (fr) 2010-07-29
UA102709C2 (uk) 2013-08-12
JP6063123B2 (ja) 2017-01-18
CO6382082A2 (es) 2012-02-15
ZA201104108B (en) 2012-09-26
BRPI0921705A2 (pt) 2015-08-25
JP2017031164A (ja) 2017-02-09
CR20110320A (es) 2011-10-18
CN103705942A (zh) 2014-04-09
BRPI0921705B1 (pt) 2021-01-19
CN103705942B (zh) 2016-08-24
SV2011003907A (es) 2011-12-06
NZ593345A (en) 2013-04-26
KR20120008020A (ko) 2012-01-25
JP2015091856A (ja) 2015-05-14
CN104958296B (zh) 2017-12-01
MY194407A (en) 2022-11-30
CN104958296A (zh) 2015-10-07
CN102215690B (zh) 2015-07-01
ECSP11011119A (es) 2011-11-30
IL212781A (en) 2016-12-29
AU2009314072C1 (en) 2016-11-10
MX2011005117A (es) 2011-10-21
US20220265636A1 (en) 2022-08-25
EA201170689A1 (ru) 2013-10-30
WO2010056872A2 (fr) 2010-05-20
PE20120029A1 (es) 2012-02-13
US20240307368A1 (en) 2024-09-19
BR122020021551B1 (pt) 2021-09-21
EP2373166A4 (fr) 2014-11-05
CN102215690A (zh) 2011-10-12
JP6407221B2 (ja) 2018-10-17
KR101767689B1 (ko) 2017-08-11
CA2743419C (fr) 2017-02-14
MY188453A (en) 2021-12-09
JP2012508757A (ja) 2012-04-12
US20120065186A1 (en) 2012-03-15
AU2009314072A1 (en) 2011-06-30
AU2009314072B2 (en) 2016-05-19
HK1213821A1 (zh) 2016-07-15
EP2373166A2 (fr) 2011-10-12
CA2743419A1 (fr) 2010-05-20
PE20160116A1 (es) 2016-03-09
IL212781A0 (en) 2011-07-31
EA025637B1 (ru) 2017-01-30
NI201100097A (es) 2011-09-08
US20160235736A1 (en) 2016-08-18
BRPI0921705B8 (pt) 2021-05-25
US20200022971A1 (en) 2020-01-23
MY161597A (en) 2017-04-28

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