MA30708B1 - Composes de 2-amido-4-isoxazolyl thiazole presentant une activite inhibitrice d'une enzyme utilisant l'atp et compositions et utilisation desdits composes. - Google Patents

Composes de 2-amido-4-isoxazolyl thiazole presentant une activite inhibitrice d'une enzyme utilisant l'atp et compositions et utilisation desdits composes.

Info

Publication number
MA30708B1
MA30708B1 MA31702A MA31702A MA30708B1 MA 30708 B1 MA30708 B1 MA 30708B1 MA 31702 A MA31702 A MA 31702A MA 31702 A MA31702 A MA 31702A MA 30708 B1 MA30708 B1 MA 30708B1
Authority
MA
Morocco
Prior art keywords
atp
enzyme
amido
compositions
isoxazolyl
Prior art date
Application number
MA31702A
Other languages
English (en)
Inventor
John K Dickson Jr
Carl Nicholas Hodge
Ke Chen
Original Assignee
Genentech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genentech Inc filed Critical Genentech Inc
Publication of MA30708B1 publication Critical patent/MA30708B1/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/427—Thiazoles not condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

L'INVENTION CONCERNE DES COMPOSÉS DE 2-AMIDO-4-ISOXAZOLYL THIAZOLE PRÉSENTANT UNE ACTIVITÉ INHIBITRICE D'UNE ENZYME UTILISANT L'ATP, DES PROCÉDÉS D'UTILISATION DE COMPOSÉS PRÉSENTANT UNE ACTIVITÉ INHIBITRICE D'UNE ENZYME UTILISANT L'ATP, ET DES COMPOSITIONS COMPRENANT DES COMPOSÉS PRÉSENTANT UNE ACTIVITÉ INHIBITRICE D'UNE ENZYME UTILISANT L'ATP.
MA31702A 2006-08-16 2009-03-09 Composes de 2-amido-4-isoxazolyl thiazole presentant une activite inhibitrice d'une enzyme utilisant l'atp et compositions et utilisation desdits composes. MA30708B1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US83824306P 2006-08-16 2006-08-16

Publications (1)

Publication Number Publication Date
MA30708B1 true MA30708B1 (fr) 2009-09-01

Family

ID=38982868

Family Applications (1)

Application Number Title Priority Date Filing Date
MA31702A MA30708B1 (fr) 2006-08-16 2009-03-09 Composes de 2-amido-4-isoxazolyl thiazole presentant une activite inhibitrice d'une enzyme utilisant l'atp et compositions et utilisation desdits composes.

Country Status (16)

Country Link
US (1) US20080242709A1 (fr)
EP (1) EP2057157A2 (fr)
JP (1) JP2010500998A (fr)
KR (1) KR20090038905A (fr)
CN (1) CN101522675A (fr)
AU (1) AU2007286111A1 (fr)
BR (1) BRPI0714535A2 (fr)
CA (1) CA2659276A1 (fr)
CR (1) CR10616A (fr)
IL (1) IL196717A0 (fr)
MA (1) MA30708B1 (fr)
MX (1) MX2009001625A (fr)
NO (1) NO20091107L (fr)
RU (1) RU2009109205A (fr)
WO (1) WO2008022002A2 (fr)
ZA (1) ZA200900605B (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2575466A1 (fr) * 2004-08-13 2006-02-23 Genentech, Inc. Composes a base de 2-amido-thiazole presentant une activite inhibitrice enzymatique utilisant de l'adenosine triphosphate (atp), et compositions, et leurs utilisations

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2575466A1 (fr) * 2004-08-13 2006-02-23 Genentech, Inc. Composes a base de 2-amido-thiazole presentant une activite inhibitrice enzymatique utilisant de l'adenosine triphosphate (atp), et compositions, et leurs utilisations

Also Published As

Publication number Publication date
JP2010500998A (ja) 2010-01-14
KR20090038905A (ko) 2009-04-21
CA2659276A1 (fr) 2008-02-21
CR10616A (es) 2009-05-25
CN101522675A (zh) 2009-09-02
NO20091107L (no) 2009-05-15
WO2008022002A3 (fr) 2008-10-09
WO2008022002A2 (fr) 2008-02-21
ZA200900605B (en) 2010-04-28
EP2057157A2 (fr) 2009-05-13
AU2007286111A1 (en) 2008-02-21
US20080242709A1 (en) 2008-10-02
MX2009001625A (es) 2009-02-23
BRPI0714535A2 (pt) 2013-07-02
IL196717A0 (en) 2009-11-18
RU2009109205A (ru) 2010-09-27

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