MA29094B1 - PROCEDE DE FABRICATION D'OXAZOLES PAR CONDENSATION D'ALDEHYDES AROMATIQUES AVEC DES alpha-CETOXIMES AFIN DE PRODUIRE DES N-OXYDES ET REACTION CONSECUTIVE AVEC DES DERIVES D'ACIDE ACTIVES - Google Patents

PROCEDE DE FABRICATION D'OXAZOLES PAR CONDENSATION D'ALDEHYDES AROMATIQUES AVEC DES alpha-CETOXIMES AFIN DE PRODUIRE DES N-OXYDES ET REACTION CONSECUTIVE AVEC DES DERIVES D'ACIDE ACTIVES

Info

Publication number
MA29094B1
MA29094B1 MA29988A MA29988A MA29094B1 MA 29094 B1 MA29094 B1 MA 29094B1 MA 29988 A MA29988 A MA 29988A MA 29988 A MA29988 A MA 29988A MA 29094 B1 MA29094 B1 MA 29094B1
Authority
MA
Morocco
Prior art keywords
ketoximes
oxazoles
condensation
oxides
produce
Prior art date
Application number
MA29988A
Other languages
English (en)
Inventor
Wolfgang Holla
Rolf-Ludwig Hoerlein
Berndt Kulitzscher
Wolfgang Laux
Thomas Stuedemann
Christoph Tappertzhofen
Robert J H Scheffer
Original Assignee
Sanofi Aventis Deutschland
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Aventis Deutschland filed Critical Sanofi Aventis Deutschland
Publication of MA29094B1 publication Critical patent/MA29094B1/fr

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D263/00Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/30Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D263/32Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D263/00Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/30Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D263/34Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D263/36One oxygen atom
    • C07D263/40One oxygen atom attached in position 4
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D263/00Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/30Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D263/34Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D263/36One oxygen atom
    • C07D263/42One oxygen atom attached in position 5

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Epidemiology (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
MA29988A 2004-12-15 2007-06-12 PROCEDE DE FABRICATION D'OXAZOLES PAR CONDENSATION D'ALDEHYDES AROMATIQUES AVEC DES alpha-CETOXIMES AFIN DE PRODUIRE DES N-OXYDES ET REACTION CONSECUTIVE AVEC DES DERIVES D'ACIDE ACTIVES MA29094B1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE102004060227A DE102004060227B3 (de) 2004-12-15 2004-12-15 Verfahren zur Herstellung von Oxazolen durch Kondensation von aromatischen Aldehyden mit α-Ketoximen zu N-Oxiden und nachfolgende Reaktion mit aktivierten Säurederivaten

Publications (1)

Publication Number Publication Date
MA29094B1 true MA29094B1 (fr) 2007-12-03

Family

ID=36064837

Family Applications (1)

Application Number Title Priority Date Filing Date
MA29988A MA29094B1 (fr) 2004-12-15 2007-06-12 PROCEDE DE FABRICATION D'OXAZOLES PAR CONDENSATION D'ALDEHYDES AROMATIQUES AVEC DES alpha-CETOXIMES AFIN DE PRODUIRE DES N-OXYDES ET REACTION CONSECUTIVE AVEC DES DERIVES D'ACIDE ACTIVES

Country Status (19)

Country Link
US (3) US7544809B2 (fr)
EP (1) EP1828149B1 (fr)
JP (1) JP2008523124A (fr)
KR (1) KR20070089165A (fr)
CN (1) CN101080398A (fr)
AR (1) AR052267A1 (fr)
AU (1) AU2005318635A1 (fr)
BR (1) BRPI0519918A2 (fr)
CA (1) CA2590494A1 (fr)
DE (1) DE102004060227B3 (fr)
MA (1) MA29094B1 (fr)
MX (1) MX2007006676A (fr)
NO (1) NO20073144L (fr)
NZ (1) NZ555670A (fr)
RU (1) RU2402537C2 (fr)
TW (1) TW200635907A (fr)
UY (1) UY29257A1 (fr)
WO (1) WO2006066694A1 (fr)
ZA (1) ZA200704027B (fr)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7816385B2 (en) * 2002-12-20 2010-10-19 High Point Pharmaceuticals, Llc Dimeric dicarboxylic acid derivatives, their preparation and use
DE102004060227B3 (de) * 2004-12-15 2006-07-20 Sanofi-Aventis Deutschland Gmbh Verfahren zur Herstellung von Oxazolen durch Kondensation von aromatischen Aldehyden mit α-Ketoximen zu N-Oxiden und nachfolgende Reaktion mit aktivierten Säurederivaten
US8722731B2 (en) 2010-06-07 2014-05-13 Novomedix, Llc Furanyl compounds and the use thereof

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5036079A (en) * 1989-12-07 1991-07-30 Pfizer Inc. Hypoglycemic thiazolidinedione derivatives
JP2004506722A (ja) * 2000-08-23 2004-03-04 イーライ・リリー・アンド・カンパニー ペルオキシソーム増殖因子活性化受容体の調節方法
JP2005502600A (ja) * 2001-06-07 2005-01-27 イーライ・リリー・アンド・カンパニー ペルオキシソーム増殖因子活性化受容体(ppar)のモジュレーター
DE10308353A1 (de) * 2003-02-27 2004-12-02 Aventis Pharma Deutschland Gmbh Diarylcycloalkylderivate, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
DE10308355A1 (de) * 2003-02-27 2004-12-23 Aventis Pharma Deutschland Gmbh Aryl-cycloalkyl substituierte Alkansäurederivate, Verfahren zu ihrer Herstellung und ihre Anwendung als Arzneimittel
DE102004060227B3 (de) * 2004-12-15 2006-07-20 Sanofi-Aventis Deutschland Gmbh Verfahren zur Herstellung von Oxazolen durch Kondensation von aromatischen Aldehyden mit α-Ketoximen zu N-Oxiden und nachfolgende Reaktion mit aktivierten Säurederivaten

Also Published As

Publication number Publication date
US7825144B2 (en) 2010-11-02
RU2007126844A (ru) 2009-01-27
DE102004060227B3 (de) 2006-07-20
WO2006066694A1 (fr) 2006-06-29
MX2007006676A (es) 2007-08-14
BRPI0519918A2 (pt) 2009-04-07
UY29257A1 (es) 2006-07-31
CN101080398A (zh) 2007-11-28
US20090286988A1 (en) 2009-11-19
AR052267A1 (es) 2007-03-07
CA2590494A1 (fr) 2006-06-29
ZA200704027B (en) 2008-07-30
KR20070089165A (ko) 2007-08-30
NZ555670A (en) 2010-09-30
US20080114035A1 (en) 2008-05-15
NO20073144L (no) 2007-09-11
AU2005318635A1 (en) 2006-06-29
EP1828149A1 (fr) 2007-09-05
JP2008523124A (ja) 2008-07-03
US7544809B2 (en) 2009-06-09
TW200635907A (en) 2006-10-16
US20080058529A1 (en) 2008-03-06
EP1828149B1 (fr) 2015-01-21
RU2402537C2 (ru) 2010-10-27

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