MA24359A1 - PROCEDE POUR LA FORMULATION NOUVELLE DE MONOCHLORHYDRATE DE [R-(Z)-alpha-(METHOXYIMINO-ALPHA-(1-AZABICYCLO[2-2-2] OCT-3-YL)-ACETONITRIYLE? - Google Patents

PROCEDE POUR LA FORMULATION NOUVELLE DE MONOCHLORHYDRATE DE [R-(Z)-alpha-(METHOXYIMINO-ALPHA-(1-AZABICYCLO[2-2-2] OCT-3-YL)-ACETONITRIYLE?

Info

Publication number
MA24359A1
MA24359A1 MA24792A MA24792A MA24359A1 MA 24359 A1 MA24359 A1 MA 24359A1 MA 24792 A MA24792 A MA 24792A MA 24792 A MA24792 A MA 24792A MA 24359 A1 MA24359 A1 MA 24359A1
Authority
MA
Morocco
Prior art keywords
alpha
acetonitriyle
monochlorhydrate
methoxyimino
azabicyclo
Prior art date
Application number
MA24792A
Other languages
English (en)
French (fr)
Original Assignee
Smithkline Beecham Corp
Smithkline Beecham Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beecham Corp, Smithkline Beecham Plc filed Critical Smithkline Beecham Corp
Publication of MA24359A1 publication Critical patent/MA24359A1/fr

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/439Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom the ring forming part of a bridged ring system, e.g. quinuclidine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605Excipients; Inactive ingredients
    • A61K9/1617Organic compounds, e.g. phospholipids, fats
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/205Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/205Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2059Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2072Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2086Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A61K9/5078Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Hospice & Palliative Care (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Psychiatry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
MA24792A 1996-09-12 1997-09-10 PROCEDE POUR LA FORMULATION NOUVELLE DE MONOCHLORHYDRATE DE [R-(Z)-alpha-(METHOXYIMINO-ALPHA-(1-AZABICYCLO[2-2-2] OCT-3-YL)-ACETONITRIYLE? MA24359A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB9619074.9A GB9619074D0 (en) 1996-09-12 1996-09-12 Composition

Publications (1)

Publication Number Publication Date
MA24359A1 true MA24359A1 (fr) 1998-07-01

Family

ID=10799833

Family Applications (1)

Application Number Title Priority Date Filing Date
MA24792A MA24359A1 (fr) 1996-09-12 1997-09-10 PROCEDE POUR LA FORMULATION NOUVELLE DE MONOCHLORHYDRATE DE [R-(Z)-alpha-(METHOXYIMINO-ALPHA-(1-AZABICYCLO[2-2-2] OCT-3-YL)-ACETONITRIYLE?

Country Status (22)

Country Link
EP (1) EP0929301A2 (no)
JP (1) JP2001500150A (no)
KR (1) KR20000036039A (no)
CN (2) CN1235544A (no)
AR (1) AR008176A1 (no)
AU (1) AU724086B2 (no)
BR (1) BR9711734A (no)
CA (1) CA2265661A1 (no)
CO (1) CO5031291A1 (no)
CZ (1) CZ83299A3 (no)
GB (1) GB9619074D0 (no)
HU (1) HUP9904401A3 (no)
ID (1) ID19589A (no)
IL (1) IL128781A0 (no)
MA (1) MA24359A1 (no)
NO (1) NO991194D0 (no)
NZ (1) NZ334268A (no)
PE (1) PE2499A1 (no)
PL (1) PL332074A1 (no)
TR (1) TR199900505T2 (no)
WO (1) WO1998010762A2 (no)
ZA (1) ZA978133B (no)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2775597B1 (fr) * 1998-03-04 2001-04-20 Gattefosse Ets Sa Pellet administrable par voie orale apte a ameliorer la biodisponibilite de la substance active, procede de fabrication
CN1292696A (zh) 1998-03-11 2001-04-25 史密丝克莱恩比彻姆有限公司 组合物
DE19918325A1 (de) * 1999-04-22 2000-10-26 Euro Celtique Sa Verfahren zur Herstellung von Arzneiformen mit regulierter Wirkstofffreisetzung mittels Extrusion
FR2796840B1 (fr) * 1999-07-26 2003-06-20 Ethypharm Lab Prod Ethiques Comprimes faiblement doses et procede de preparation
US6733781B2 (en) * 2000-12-06 2004-05-11 Wyeth Fast dissolving tablet
US8679533B2 (en) 2002-07-25 2014-03-25 Pharmacia Corporation Pramipexole once-daily dosage form
US20060252820A1 (en) * 2003-04-25 2006-11-09 Tetsuya Suzuki Composition for oral administration containing alkylene dioxybenzene derivative
DE602004002405T3 (de) * 2003-05-14 2013-06-20 Aptalis Pharma Limited Kontrollierte medikamentfreigabe zusammensetzung mit in vivo mechanikstresswiderstand
US20050142191A1 (en) * 2003-06-23 2005-06-30 Neurochem (International) Limited Pharmaceutical formulations of amyloid inhibiting compounds
JP2005272347A (ja) * 2004-03-24 2005-10-06 Ohara Yakuhin Kogyo Kk 固形製剤の製造方法
WO2006015943A2 (en) 2004-08-13 2006-02-16 Boehringer Ingelheim International Gmbh Extended release pellet formulation containing pramipexole or a pharmaceutically acceptable salt thereof, method for manufacturing the same and use thereof
EP2345407A1 (en) 2004-08-13 2011-07-20 Boehringer Ingelheim International GmbH Extended release tablet formulation containing pramipexole or a pharmaceutically acceptable salt thereof, method for manufacturing the same and use thereof
EP1970056A1 (en) * 2007-03-15 2008-09-17 Polichem S.A. Time-specific delayed/pulsatile release dosage forms
US9132096B1 (en) 2014-09-12 2015-09-15 Alkermes Pharma Ireland Limited Abuse resistant pharmaceutical compositions

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK0392803T3 (da) * 1989-04-13 2004-10-18 Beecham Group Plc Hidtil ukendte forbindelser
GB9409718D0 (en) * 1994-05-14 1994-07-06 Smithkline Beecham Plc Novel compounds
GB9421472D0 (en) * 1994-10-25 1994-12-07 Smithkline Beecham Plc Novel methods
AR004178A1 (es) * 1995-07-29 1998-11-04 Smithkline Beecham Plc Procedimiento para la formulacion de un farmaco, una composicion farmaceutica obtenible mediante este procedimiento y el uso de la misma.

Also Published As

Publication number Publication date
CA2265661A1 (en) 1998-03-19
NO991194L (no) 1999-03-11
CO5031291A1 (es) 2001-04-27
NO991194D0 (no) 1999-03-11
HUP9904401A3 (en) 2001-03-28
CN1235544A (zh) 1999-11-17
ID19589A (id) 1998-07-23
KR20000036039A (ko) 2000-06-26
WO1998010762A3 (en) 1998-06-04
PE2499A1 (es) 1999-03-24
WO1998010762A2 (en) 1998-03-19
CZ83299A3 (cs) 1999-08-11
ZA978133B (en) 1999-04-12
JP2001500150A (ja) 2001-01-09
BR9711734A (pt) 1999-08-24
TR199900505T2 (no) 1999-06-21
CN1446535A (zh) 2003-10-08
GB9619074D0 (en) 1996-10-23
HUP9904401A2 (hu) 2000-06-28
IL128781A0 (en) 2000-01-31
PL332074A1 (en) 1999-08-30
AU724086B2 (en) 2000-09-14
NZ334268A (en) 2000-10-27
EP0929301A2 (en) 1999-07-21
AR008176A1 (es) 1999-12-09
AU4128897A (en) 1998-04-02

Similar Documents

Publication Publication Date Title
FR2791580B1 (fr) Procede pour l'enrobage de particules
MA24359A1 (fr) PROCEDE POUR LA FORMULATION NOUVELLE DE MONOCHLORHYDRATE DE [R-(Z)-alpha-(METHOXYIMINO-ALPHA-(1-AZABICYCLO[2-2-2] OCT-3-YL)-ACETONITRIYLE?
MA23998A1 (fr) Procede pour la preparation du d-tartrate de (-) cis-6 (s) -phenyl -5 (r) -[4-(2-pyrrolidine-1-ylethoxy)- phenyl] -5,6,7,8-tetrahydronaphtalene -2-01
AU3124297A (en) Conoscopic system for real-time corneal topography
MA23395A1 (fr) Procede de preparation de nouvelles formulations
GR3033390T3 (en) Process for the preparation of O-demethyltramadol enantiomers
MA24437A1 (fr) Procede de la preparation et de la formulation de dihydrate d'eprosartan
AU6222096A (en) Phenoxy piperazine derivatives for treating disorders of the dopamine system
AU6221896A (en) Process for the hydrogenation of imines
MA24182A1 (fr) Procede pour la preparation de 2,4-diaminopyrimidines substituees
MA22848A1 (fr) Procede enzymatique pour la preparation des aryl-piperidines
AU1563899A (en) Method for finishing ball cages meant for homocinetic joints
EE03393B1 (et) Protsess enantiomeerselt puhta asetidiin-2-karboksüülhappe saamiseks
FR2733227B1 (fr) Procede pour la preparation de 1,1-difluoroethane
AU5320998A (en) Microparticles containing active substances, agents containing the same, their use in ultrasound-controlled releasing of active substances as well as the method for their production
GB9611041D0 (en) Process for the preparation of optically active methadones in high enantiomeric purity
EP0945518A4 (en) PROCESS FOR PRODUCING OPTICALLY ACTIVE DERIVATIVES OF 3-QUINUCLIDINOL
IL118788A0 (en) Process for the hydrogenation of imines
HUP0000807A3 (en) Process for the preparation of optically active n-benzyl-3-pyrrolidinol
FR2753451B1 (fr) Procede de fabrication de d-erythrose
AU2838397A (en) Process for the preparation of optically active amines
AU6657296A (en) Process for the hydrogenation of imines
MA24015A1 (fr) Procede pour la preparation de dioxo-azabicyclohexanes
MA24078A1 (fr) Procede pour l'utilisation de derives de tetrahydroisoquinoleine
FR2750998B1 (fr) Procede de preparation de k-carraghenase