LV11544B - N-££1-£4-(4-fluorophenoxy) butyl|-4- piperidinyl|-n- methylamino|-2- benzothiazolols as class iii antiarrhythmic agents - Google Patents

N-££1-£4-(4-fluorophenoxy) butyl|-4- piperidinyl|-n- methylamino|-2- benzothiazolols as class iii antiarrhythmic agents Download PDF

Info

Publication number
LV11544B
LV11544B LVP-96-06A LV960006A LV11544B LV 11544 B LV11544 B LV 11544B LV 960006 A LV960006 A LV 960006A LV 11544 B LV11544 B LV 11544B
Authority
LV
Latvia
Prior art keywords
compound
piperidinyl
butyl
formula
methylamino
Prior art date
Application number
LVP-96-06A
Other languages
English (en)
Latvian (lv)
Other versions
LV11544A (lv
Inventor
Heykants Jozef Jan Pieter
Borgers Marcel Jan Maria
Wilhelm Doris
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Publication of LV11544A publication Critical patent/LV11544A/xx
Publication of LV11544B publication Critical patent/LV11544B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Silver Salt Photography Or Processing Solution Therefor (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Plural Heterocyclic Compounds (AREA)
LVP-96-06A 1993-06-11 1996-01-11 N-££1-£4-(4-fluorophenoxy) butyl|-4- piperidinyl|-n- methylamino|-2- benzothiazolols as class iii antiarrhythmic agents LV11544B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP93201685 1993-06-11
PCT/EP1994/001849 WO1994029305A1 (en) 1993-06-11 1994-06-06 N-[[1-[4-(4-fluorophenoxy)butyl]-4-piperidinyl]-n-methylamino]-2-benzothiazolols as class iii antiarrhythmic agents

Publications (2)

Publication Number Publication Date
LV11544A LV11544A (lv) 1996-10-20
LV11544B true LV11544B (en) 1997-08-20

Family

ID=8213890

Family Applications (1)

Application Number Title Priority Date Filing Date
LVP-96-06A LV11544B (en) 1993-06-11 1996-01-11 N-££1-£4-(4-fluorophenoxy) butyl|-4- piperidinyl|-n- methylamino|-2- benzothiazolols as class iii antiarrhythmic agents

Country Status (34)

Country Link
US (1) US5691354A (ru)
EP (1) EP0701556B1 (ru)
JP (1) JP3498145B2 (ru)
KR (1) KR100337984B1 (ru)
CN (1) CN1039120C (ru)
AT (1) ATE159254T1 (ru)
AU (1) AU678841B2 (ru)
BG (1) BG62968B1 (ru)
BR (1) BR9406765A (ru)
CA (1) CA2163018A1 (ru)
CZ (1) CZ285766B6 (ru)
DE (1) DE69406284T2 (ru)
DK (1) DK0701556T3 (ru)
ES (1) ES2108471T3 (ru)
FI (1) FI955916A0 (ru)
GR (1) GR3025805T3 (ru)
HU (1) HU221620B1 (ru)
IL (1) IL109975A (ru)
LV (1) LV11544B (ru)
MY (1) MY111222A (ru)
NO (1) NO305123B1 (ru)
NZ (1) NZ268575A (ru)
OA (1) OA10201A (ru)
PH (1) PH31126A (ru)
PL (1) PL176775B1 (ru)
RO (1) RO115523B1 (ru)
RU (1) RU2122546C1 (ru)
SG (1) SG48821A1 (ru)
SI (1) SI9420036A (ru)
SK (1) SK281175B6 (ru)
TW (1) TW282469B (ru)
UA (1) UA41936C2 (ru)
WO (1) WO1994029305A1 (ru)
ZA (1) ZA944106B (ru)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ520041A (en) 2000-01-20 2004-11-26 Eisai Co Ltd Novel piperidine compounds and drugs containing the same

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5010198A (en) * 1984-12-03 1991-04-23 Janssen Pharmaceutica N.V. Intermediates for the synthesis of benzoxazol- and benzothiazolamine derivatives, useful as anti-anoxic agents
US4861785A (en) * 1984-12-03 1989-08-29 Janssen Pharmaceutica N.V. Benzoxazol-and benzothiazolamine derivatives, useful as anti-anoxic agents
CA1260474A (en) * 1984-12-03 1989-09-26 Raymond A. Stokbroekx Benzoxazol- and benzothiazolamine derivatives
US4749702A (en) * 1985-04-15 1988-06-07 Janssen Pharmaceutica N. V. Antidepressive substituted N-[(4-piperidinyl)alkyl] bicyclic condensed oxazol- and thiazolamines
KR930005004B1 (ko) * 1985-04-15 1993-06-11 쟈안센 파아마슈우티카 엔. 부이. 치환된 n-[(4-피페리디닐)알킬]이환 축합 옥사졸아민 및 티아졸아민의 제조방법
ZW1992A1 (en) * 1991-02-25 1993-09-22 Janssen Pharmaceutica Nv 4-/(2-benzotiazolyl)methylamino/-b-/(3,4-difluorephenoxy)methyl/-1-piperidine ethanol

Also Published As

Publication number Publication date
NO954801D0 (no) 1995-11-27
BR9406765A (pt) 1996-02-21
DK0701556T3 (da) 1998-01-26
NO305123B1 (no) 1999-04-06
SG48821A1 (en) 1998-05-18
CZ285766B6 (cs) 1999-11-17
CN1039120C (zh) 1998-07-15
IL109975A0 (en) 1994-10-07
HU221620B1 (hu) 2002-12-28
DE69406284D1 (de) 1997-11-20
EP0701556A1 (en) 1996-03-20
RO115523B1 (ro) 2000-03-30
RU2122546C1 (ru) 1998-11-27
UA41936C2 (ru) 2001-10-15
KR100337984B1 (ko) 2002-10-25
ZA944106B (en) 1995-12-11
DE69406284T2 (de) 1998-02-19
AU678841B2 (en) 1997-06-12
MY111222A (en) 1999-09-30
CA2163018A1 (en) 1994-12-22
WO1994029305A1 (en) 1994-12-22
EP0701556B1 (en) 1997-10-15
SI9420036A (en) 1996-10-31
PL311965A1 (en) 1996-03-18
HU9501971D0 (en) 1995-09-28
US5691354A (en) 1997-11-25
SK154495A3 (en) 1996-06-05
FI955916A (fi) 1995-12-08
CN1125443A (zh) 1996-06-26
HUT73679A (en) 1996-09-30
PH31126A (en) 1998-02-23
BG62968B1 (bg) 2000-12-29
NZ268575A (en) 1996-08-27
PL176775B1 (pl) 1999-07-30
BG100210A (bg) 1996-07-31
SK281175B6 (sk) 2000-12-11
JPH08511014A (ja) 1996-11-19
TW282469B (ru) 1996-08-01
ES2108471T3 (es) 1997-12-16
CZ319295A3 (en) 1996-03-13
GR3025805T3 (en) 1998-03-31
IL109975A (en) 1999-04-11
JP3498145B2 (ja) 2004-02-16
NO954801L (no) 1995-11-27
ATE159254T1 (de) 1997-11-15
AU7183894A (en) 1995-01-03
OA10201A (en) 1996-12-18
FI955916A0 (fi) 1995-12-08
LV11544A (lv) 1996-10-20

Similar Documents

Publication Publication Date Title
EP1378247B1 (en) Visual function disorder improving agents
EP0483772B1 (en) Aminocoumaran derivatives, their production and use
EP0359389A1 (en) Antiarrhythmic agents
HU221317B1 (en) 2,4-imidazolidinedione derivatives and antiarrhythmic and antifibrillatory compositions containing them, and process for producing them
JPH09501405A (ja) 抗不整脈用ｎ−置換３−ベンズアゼピンまたはイソキノリン
EP0701556B1 (en) N-((1-(4-fluorophenoxy)butyl)-4-piperidinyl)-n-methylamino-2-benzothiazolols as class iii antiarrhythmic agents
AU650031B2 (en) 1-Piperidinyl alkanoylarylsulfonamide derivatives
US5240943A (en) Benzopyran class iii antiarrhythmic agents
JP3885900B2 (ja) ベンゾピラン誘導体及びそれを有効成分とする心臓疾患治療剤
US5132311A (en) Cyanoquanidine type III antiarrhythmic agents and use
US5541201A (en) Antiarrhythmic piperidin-1-yl-2,2-dialkylpropanone arylsulfonamide derivatives
ES2255245T3 (es) Agentes de reduccion del porcentaje de lp (a) e inhibidores de la produccion de apoproteina (a).
KR100522008B1 (ko) 심장병 치료 및 예방에 있어서의 탈리포르핀 또는 그유도체의 용도
AU2001248226A1 (en) Uses of thaliporphine or its derivatives in treatment of cardiac diseases and preparation of same
RU2087473C1 (ru) Производные аминокумарана или их соли, способы их получения, композиция для ингибирования образования липопероксида
US5104892A (en) Substituted benzimidazole derivatives possessing Class III antiarrhythmic activity