LU91218I2 - Omalizumab et ses formes pharmaceutiquement acceptables - Google Patents
Omalizumab et ses formes pharmaceutiquement acceptablesInfo
- Publication number
- LU91218I2 LU91218I2 LU91218C LU91218C LU91218I2 LU 91218 I2 LU91218 I2 LU 91218I2 LU 91218 C LU91218 C LU 91218C LU 91218 C LU91218 C LU 91218C LU 91218 I2 LU91218 I2 LU 91218I2
- Authority
- LU
- Luxembourg
- Prior art keywords
- ige
- omalizumab
- pharmaceutically acceptable
- epsilon
- acceptable forms
- Prior art date
Links
- 229960000470 omalizumab Drugs 0.000 title 1
- 210000003719 b-lymphocyte Anatomy 0.000 abstract 2
- 230000000890 antigenic effect Effects 0.000 abstract 1
- 210000003651 basophil Anatomy 0.000 abstract 1
- 239000012528 membrane Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
- A61K47/64—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
- A61K47/643—Albumins, e.g. HSA, BSA, ovalbumin or a Keyhole Limpet Hemocyanin [KHL]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/68—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
- A61K47/6835—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site
- A61K47/6873—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site the antibody targeting an immunoglobulin; the antibody being an anti-idiotypic antibody
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/42—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins
- C07K16/4208—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins against an idiotypic determinant on Ig
- C07K16/4241—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins against an idiotypic determinant on Ig against anti-human or anti-animal Ig
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/42—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins
- C07K16/4283—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins against an allotypic or isotypic determinant on Ig
- C07K16/4291—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins against an allotypic or isotypic determinant on Ig against IgE
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/33—Fusion polypeptide fusions for targeting to specific cell types, e.g. tissue specific targeting, targeting of a bacterial subspecies
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Immunology (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Molecular Biology (AREA)
- Epidemiology (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Pulmonology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Saccharide Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US14003687A | 1987-12-31 | 1987-12-31 | |
US07/226,421 US5422258A (en) | 1987-12-31 | 1988-07-29 | Methods for producing high affinity anti-human IgE-monoclonal antibodies which binds to IgE on IgEabearing B cells but not basophils |
US22917888A | 1988-08-05 | 1988-08-05 | |
US07/272,243 US5091313A (en) | 1988-08-05 | 1988-11-16 | Antigenic epitopes of IgE present on B cell but not basophil surface |
US29106888A | 1988-12-28 | 1988-12-28 |
Publications (1)
Publication Number | Publication Date |
---|---|
LU91218I2 true LU91218I2 (fr) | 2006-04-03 |
Family
ID=27538114
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
LU91218C LU91218I2 (fr) | 1987-12-31 | 2006-02-02 | Omalizumab et ses formes pharmaceutiquement acceptables |
Country Status (10)
Country | Link |
---|---|
EP (2) | EP0617127A1 (fr) |
JP (1) | JP2724625B2 (fr) |
AT (1) | ATE121299T1 (fr) |
AU (1) | AU618317B2 (fr) |
CA (1) | CA1340233C (fr) |
DE (3) | DE122006000007I1 (fr) |
HK (1) | HK31096A (fr) |
LU (1) | LU91218I2 (fr) |
NL (1) | NL300222I2 (fr) |
WO (1) | WO1989006138A1 (fr) |
Families Citing this family (47)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5362643A (en) * | 1989-06-21 | 1994-11-08 | Tanox Biosystems | Antibodies to epitopes present on membrane-bound but not secreted IGA |
US5449760A (en) * | 1987-12-31 | 1995-09-12 | Tanox Biosystems, Inc. | Monoclonal antibodies that bind to soluble IGE but do not bind IGE on IGE expressing B lymphocytes or basophils |
US5089603A (en) * | 1989-06-21 | 1992-02-18 | Tanox Biosystems, Inc. | Antigenic epitopes present on membrane-bound but not secreted iga |
US5254671A (en) * | 1990-04-27 | 1993-10-19 | Tanox Biosystems, Inc. | Extracellular segments of human e immunoglobulin anchoring peptides and antibodies specific therefor |
EP0397764A1 (fr) * | 1988-02-02 | 1990-11-22 | Schering Biotech Corporation | Procede de reduction des reactions dues a l'immunoglobuline e |
AU639719B2 (en) * | 1989-09-15 | 1993-08-05 | Tanox Biosystems, Inc. | Treatment of autoimmune disease |
DE69126607T2 (de) * | 1990-01-23 | 1998-01-15 | Tanox Biosystems, Inc., Houston, Tex. | Extrazelluläre teilstücke humaner ige-immunoglobulin-ankerpeptide und dafür spezifische antikörper |
WO1992017207A1 (fr) * | 1991-03-26 | 1992-10-15 | Tanox Biosystems, Inc. | ANTICORPS MONOCLONAUX QUI SE LIENT A L'IgE SECRETEE ET LIEE AUX MEMBRANES MAIS QUI NE SE LIENT PAS A L'IgE SE TROUVANT SUR LES LEUCOCYTES BASOPHILES |
US5965709A (en) * | 1991-08-14 | 1999-10-12 | Genentech, Inc. | IgE antagonists |
DE122006000006I2 (de) * | 1991-08-14 | 2011-06-16 | Genentech Inc | Veränderte Immunglobuline für spezifische FC-Epsilon Rezeptoren |
US6699472B2 (en) | 1991-08-14 | 2004-03-02 | Genentech, Inc. | Method of treating allergic disorders |
US5994514A (en) * | 1991-08-14 | 1999-11-30 | Genentech, Inc. | Immunoglobulin variants |
US6329509B1 (en) | 1991-08-14 | 2001-12-11 | Genentech, Inc. | Anti-IgE antibodies |
SE9102808L (sv) * | 1991-09-26 | 1993-03-27 | Lars T Hellman Inst F Immunolo | Vaccin, foer humant bruk, vars avsedda effekt aer att lindra symptomen eller foerhindra uppkomsten av ige-medierade allergiska reaktioner |
JP3156237B2 (ja) * | 1991-12-24 | 2001-04-16 | 雪印乳業株式会社 | 抗ヒトIgE モノクローナル抗体 |
GB9220228D0 (en) * | 1992-09-24 | 1992-11-04 | Ciba Geigy Ag | Reshaped monoclonal antibodies against an immunologlobulin isotype |
ATE264388T1 (de) * | 1992-09-24 | 2004-04-15 | Tanox Biosystems Inc | Umgestaltete monoklonale antikörper gegen ein immunglobulinisotyp |
US5958708A (en) * | 1992-09-25 | 1999-09-28 | Novartis Corporation | Reshaped monoclonal antibodies against an immunoglobulin isotype |
US6066718A (en) * | 1992-09-25 | 2000-05-23 | Novartis Corporation | Reshaped monoclonal antibodies against an immunoglobulin isotype |
ATE228536T1 (de) * | 1993-03-11 | 2002-12-15 | Tanox Biosystems Inc | Antigene epitope von ige repräsentierenden peptiden auf der b-zell-oberfläche aber nicht auf oberflächen von basophilen |
EP0619323A1 (fr) * | 1993-04-09 | 1994-10-12 | Schering-Plough | Anticorps monoclonaux humains et procédé et matériel pour les faire |
DE69501817T2 (de) * | 1994-01-18 | 1998-09-10 | Genentech Inc | Verfahren zur behandlung von parasitären infektionen unter verwendung von ige-antagonisten |
US6037453A (en) * | 1995-03-15 | 2000-03-14 | Genentech, Inc. | Immunoglobulin variants |
ZA966075B (en) * | 1995-07-27 | 1998-01-19 | Genentech Inc | Protein formulation. |
US6267958B1 (en) | 1995-07-27 | 2001-07-31 | Genentech, Inc. | Protein formulation |
JP2788979B2 (ja) * | 1995-08-28 | 1998-08-20 | タノックス バイオシステムズ インコーポレイテッド | 新規抗体及びその用途 |
CA2315944A1 (fr) | 1997-12-24 | 1999-07-08 | Diatech Pty. Ltd. | Molecules bifonctionnelles |
US6734287B1 (en) | 1998-04-09 | 2004-05-11 | Idexx Laboratories, Inc. | Specific binding proteins for treating canine allergy |
US6504013B1 (en) | 2000-02-01 | 2003-01-07 | Idexx Laboratories, Inc. | Canine allergy therapeutic recombinant chimeric anti-IgE monoclonal antibody |
US7393529B2 (en) | 1998-04-09 | 2008-07-01 | Idexx Laboratories, Inc. | Methods and compositions for inhibiting binding of IgE to a high affinity receptor |
US6913749B2 (en) | 1998-11-02 | 2005-07-05 | Resistentia Pharmaceuticals Ab | Immunogenic polypeptides for inducing anti-self IgE responses |
US6602719B1 (en) | 1999-03-26 | 2003-08-05 | Idexx Laboratories, Inc. | Method and device for detecting analytes in fluids |
US6511814B1 (en) | 1999-03-26 | 2003-01-28 | Idexx Laboratories, Inc. | Method and device for detecting analytes in fluids |
GB9908533D0 (en) * | 1999-04-14 | 1999-06-09 | Novartis Ag | Organic compounds |
JP3597140B2 (ja) | 2000-05-18 | 2004-12-02 | 日本たばこ産業株式会社 | 副刺激伝達分子ailimに対するヒトモノクローナル抗体及びその医薬用途 |
US9320792B2 (en) | 2002-11-08 | 2016-04-26 | Ablynx N.V. | Pulmonary administration of immunoglobulin single variable domains and constructs thereof |
US20060034845A1 (en) | 2002-11-08 | 2006-02-16 | Karen Silence | Single domain antibodies directed against tumor necrosis factor alpha and uses therefor |
CA2505326A1 (fr) | 2002-11-08 | 2004-05-21 | Ablynx N.V. | Procede d'administration de polypeptides therapeutiques et polypeptides associes |
PT2000481E (pt) | 2003-02-01 | 2016-06-17 | Tanox Inc | Anticorpos anti-ige humana de alta afinidade |
JP5389442B2 (ja) | 2005-09-29 | 2014-01-15 | メディミューン,エルエルシー | 膜Ig特異的抗体を同定する方法および免疫グロブリンを生成する前駆体細胞を標的化するための使用 |
AR065368A1 (es) | 2007-02-15 | 2009-06-03 | Astrazeneca Ab | Anticuerpos para moleculas de ige |
JP5723594B2 (ja) | 2007-03-22 | 2015-05-27 | ジェネンテック, インコーポレイテッド | アポトーシス性抗IgE抗体 |
EP1972640A1 (fr) * | 2007-03-23 | 2008-09-24 | Biomay AG | Anticorps induisant l'apoptose |
EP2401300B1 (fr) | 2009-02-25 | 2018-01-10 | Academia Sinica | ANTICORPS ANTI-C[epsilon]MX CAPABLES DE SE LIER AUX mIgE HUMAINS SUR DES LYMPHOCYTES B |
US9587034B2 (en) | 2012-04-20 | 2017-03-07 | Academia Sinica | Anti-mIgE antibodies that bind to the junction between CH4 and CεmX domains |
US10196458B2 (en) * | 2013-07-26 | 2019-02-05 | The Regents Of The University Of California | Anti-immunoglobulin E antibodies and methods of using thereof |
AU2018360999A1 (en) | 2017-10-31 | 2020-05-14 | Oneness Biotech Co. Ltd. | Treating IgE-mediated allergic diseases |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4946788A (en) * | 1985-06-11 | 1990-08-07 | Ciba-Geigy Corporation | Purified immunoglobulin-related factor, novel monoclonal antibodies, hybridoma cell lines, processes and applications |
US4714759A (en) * | 1985-12-02 | 1987-12-22 | Whitaker Jr Robert B | Immunotoxin therapy of allergy |
FI95203C (fi) * | 1986-11-04 | 1996-01-10 | Baylor College Medicine | Analogiamenetelmä sytotoksisen koostumuksen valmistamiseksi |
AU625613B2 (en) * | 1988-01-05 | 1992-07-16 | Novartis Ag | Novel chimeric antibodies |
GB8800078D0 (en) * | 1988-01-05 | 1988-02-10 | Ciba Geigy Ag | Novel antibodies |
-
1988
- 1988-12-29 AU AU30310/89A patent/AU618317B2/en not_active Expired
- 1988-12-29 EP EP94103256A patent/EP0617127A1/fr not_active Withdrawn
- 1988-12-29 JP JP1501629A patent/JP2724625B2/ja not_active Expired - Lifetime
- 1988-12-29 DE DE19883853636 patent/DE122006000007I1/de active Pending
- 1988-12-29 DE DE122006000007C patent/DE122006000007I2/de active Active
- 1988-12-29 WO PCT/US1988/004706 patent/WO1989006138A1/fr active IP Right Grant
- 1988-12-29 AT AT89901649T patent/ATE121299T1/de active
- 1988-12-29 DE DE3853636T patent/DE3853636T3/de not_active Expired - Lifetime
- 1988-12-29 EP EP89901649A patent/EP0407392B2/fr not_active Expired - Lifetime
-
1989
- 1989-01-03 CA CA000587431A patent/CA1340233C/fr not_active Expired - Lifetime
-
1996
- 1996-02-22 HK HK31096A patent/HK31096A/xx not_active IP Right Cessation
-
2006
- 2006-02-02 LU LU91218C patent/LU91218I2/fr unknown
- 2006-02-03 NL NL300222C patent/NL300222I2/nl unknown
Also Published As
Publication number | Publication date |
---|---|
DE122006000007I1 (de) | 2006-04-27 |
DE122006000007I2 (de) | 2008-03-27 |
EP0617127A1 (fr) | 1994-09-28 |
WO1989006138A1 (fr) | 1989-07-13 |
JP2724625B2 (ja) | 1998-03-09 |
ATE121299T1 (de) | 1995-05-15 |
DE3853636T3 (de) | 1999-04-08 |
EP0407392B1 (fr) | 1995-04-19 |
EP0407392B2 (fr) | 1998-10-28 |
JPH03501927A (ja) | 1991-05-09 |
DE3853636T2 (de) | 1995-08-24 |
AU3031089A (en) | 1989-08-01 |
NL300222I1 (nl) | 2006-04-03 |
EP0407392A1 (fr) | 1991-01-16 |
HK31096A (en) | 1996-03-01 |
AU618317B2 (en) | 1991-12-19 |
CA1340233C (fr) | 1998-12-15 |
NL300222I2 (nl) | 2006-10-02 |
DE3853636D1 (de) | 1995-05-24 |
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