LU79356A1 - Preparation d'interphenylene 8-aza-9-dioxathia-11,12-secoprostaglandines utiles comme medicaments - Google Patents

Preparation d'interphenylene 8-aza-9-dioxathia-11,12-secoprostaglandines utiles comme medicaments

Info

Publication number
LU79356A1
LU79356A1 LU79356A LU79356A LU79356A1 LU 79356 A1 LU79356 A1 LU 79356A1 LU 79356 A LU79356 A LU 79356A LU 79356 A LU79356 A LU 79356A LU 79356 A1 LU79356 A1 LU 79356A1
Authority
LU
Luxembourg
Prior art keywords
dioxathia
secoprostaglandins
interphenylene
aza
useful
Prior art date
Application number
LU79356A
Other languages
English (en)
French (fr)
Inventor
J Bicking
E Cragoe
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of LU79356A1 publication Critical patent/LU79356A1/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D309/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/02Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D309/08Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D309/10Oxygen atoms
    • C07D309/12Oxygen atoms only hydrogen atoms and one oxygen atom directly attached to ring carbon atoms, e.g. tetrahydropyranyl ethers
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C29/00Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
    • C07C29/132Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group
    • C07C29/136Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group of >C=O containing groups, e.g. —COOH
    • C07C29/143Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group of >C=O containing groups, e.g. —COOH of ketones
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/004Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reaction with organometalhalides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/76Ketones containing a keto group bound to a six-membered aromatic ring
    • C07C49/80Ketones containing a keto group bound to a six-membered aromatic ring containing halogen

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
LU79356A 1977-04-04 1978-04-03 Preparation d'interphenylene 8-aza-9-dioxathia-11,12-secoprostaglandines utiles comme medicaments LU79356A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/783,998 US4112236A (en) 1977-04-04 1977-04-04 Interphenylene 8-aza-9-dioxothia-11,12-secoprostaglandins

Publications (1)

Publication Number Publication Date
LU79356A1 true LU79356A1 (fr) 1978-11-27

Family

ID=25131052

Family Applications (1)

Application Number Title Priority Date Filing Date
LU79356A LU79356A1 (fr) 1977-04-04 1978-04-03 Preparation d'interphenylene 8-aza-9-dioxathia-11,12-secoprostaglandines utiles comme medicaments

Country Status (16)

Country Link
US (1) US4112236A (de)
AR (1) AR225727A1 (de)
AU (1) AU516540B2 (de)
BE (1) BE865624A (de)
DE (1) DE2814321A1 (de)
DK (1) DK146578A (de)
ES (1) ES468510A1 (de)
FR (1) FR2386521A1 (de)
GB (1) GB1576688A (de)
IE (1) IE46699B1 (de)
IT (1) IT1103475B (de)
LU (1) LU79356A1 (de)
NL (1) NL7802824A (de)
PT (1) PT67847B (de)
SE (1) SE7803606L (de)
ZA (1) ZA781885B (de)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2809377A1 (de) * 1978-03-04 1979-09-13 Boehringer Mannheim Gmbh Phenoxyalkylcarbonsaeure-derivate, verfahren zu deren herstellung sowie diese verbindungen enthaltende arzneimittel
DE3000377A1 (de) * 1980-01-07 1981-07-09 Boehringer Mannheim Gmbh, 6800 Mannheim Neue sulfonamide, verfahren zu deren herstellung sowie diese verbindungen enthaltende arzneimittel
DE3641099A1 (de) * 1986-12-02 1988-06-09 Hoechst Ag Verfahren zur herstellung von 4-(2'-chlorethyl)benzoesaeure
ATE390917T1 (de) * 1996-12-20 2008-04-15 Pfizer Prävention und behandlung von skeletterkrankungen mit ep2 subtyp selektiven prostaglandin e2 agonisten
UA59384C2 (uk) * 1996-12-20 2003-09-15 Пфайзер, Інк. Похідні сульфонамідів та амідів як агоністи простагландину, фармацевтична композиція та способи лікування на їх основі
US6124314A (en) 1997-10-10 2000-09-26 Pfizer Inc. Osteoporosis compounds
UA67754C2 (uk) * 1997-10-10 2004-07-15 Пфайзер, Інк. Агоністи простагландину, фармацевтична композиція на їх основі (варіанти), спосіб нарощення та збереження кісткової маси у хребетних та спосіб лікування (варіанти)
DE60120007T2 (de) 2000-01-31 2006-11-16 Pfizer Products Inc., Groton Verwendung von Aktivatoren des Prostaglandinrezeptores 4 zur Behandlung von akuter oder chronischer Niereninsuffizienz
US6858615B2 (en) 2002-02-19 2005-02-22 Parion Sciences, Inc. Phenyl guanidine sodium channel blockers
US6903105B2 (en) 2003-02-19 2005-06-07 Parion Sciences, Inc. Sodium channel blockers
US7745442B2 (en) 2003-08-20 2010-06-29 Parion Sciences, Inc. Methods of reducing risk of infection from pathogens
AR086745A1 (es) 2011-06-27 2014-01-22 Parion Sciences Inc 3,5-diamino-6-cloro-n-(n-(4-(4-(2-(hexil(2,3,4,5,6-pentahidroxihexil)amino)etoxi)fenil)butil)carbamimidoil)pirazina-2-carboxamida
DK2931713T3 (en) 2012-12-17 2017-01-30 Parion Sciences Inc CHLORPYRAZINE CARBOXAMIDE DERIVATIVES USED FOR THE TREATMENT OF DISEASES BENEFITED BY INDEPENDENT MOSPHEREWIN
KR20150095870A (ko) 2012-12-17 2015-08-21 패리온 사이언스 인코퍼레이티드 3,5-디아미노-6-클로로-n-(n-(4-페닐부틸)카르밤이미도일)피라진-2-카르복스아미드 화합물
US9102633B2 (en) 2013-12-13 2015-08-11 Parion Sciences, Inc. Arylalkyl- and aryloxyalkyl-substituted epithelial sodium channel blocking compounds

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3991106A (en) * 1974-09-13 1976-11-09 Merck & Co., Inc. 16-Ethers of 8-aza-9-dioxothia-11,12-seco-prostaglandins

Also Published As

Publication number Publication date
ZA781885B (en) 1979-06-27
PT67847B (en) 1980-04-04
SE7803606L (sv) 1978-10-05
US4112236A (en) 1978-09-05
IE780632L (en) 1978-10-04
FR2386521A1 (fr) 1978-11-03
GB1576688A (en) 1980-10-15
ES468510A1 (es) 1979-09-16
AR225727A1 (es) 1982-04-30
NL7802824A (nl) 1978-10-06
DK146578A (da) 1978-10-05
PT67847A (en) 1978-04-01
DE2814321A1 (de) 1978-10-05
AU516540B2 (en) 1981-06-11
FR2386521B1 (de) 1982-11-19
IT7848626A0 (it) 1978-03-28
IT1103475B (it) 1985-10-14
AU3436678A (en) 1979-09-27
IE46699B1 (en) 1983-08-24
BE865624A (fr) 1978-10-03

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