LU79036A1 - Steroides-11beta-substitues et procede de leur preparatio - Google Patents

Steroides-11beta-substitues et procede de leur preparatio

Info

Publication number
LU79036A1
LU79036A1 LU79036A LU79036A LU79036A1 LU 79036 A1 LU79036 A1 LU 79036A1 LU 79036 A LU79036 A LU 79036A LU 79036 A LU79036 A LU 79036A LU 79036 A1 LU79036 A1 LU 79036A1
Authority
LU
Luxembourg
Prior art keywords
11beta
steroids
substitutes
preparation
Prior art date
Application number
LU79036A
Other languages
English (en)
Inventor
G Overbeek
Original Assignee
Akzo Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Akzo Nv filed Critical Akzo Nv
Publication of LU79036A1 publication Critical patent/LU79036A1/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0051—Estrane derivatives
    • C07J1/0081—Substituted in position 17 alfa and 17 beta
    • C07J1/0085—Substituted in position 17 alfa and 17 beta the substituent in position 17 alfa being a saturated hydrocarbon group
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0051—Estrane derivatives
    • C07J1/0059—Estrane derivatives substituted in position 17 by a keto group
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0051—Estrane derivatives
    • C07J1/0066—Estrane derivatives substituted in position 17 beta not substituted in position 17 alfa
    • C07J1/007—Estrane derivatives substituted in position 17 beta not substituted in position 17 alfa the substituent being an OH group free esterified or etherified
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0051—Estrane derivatives
    • C07J1/0081—Substituted in position 17 alfa and 17 beta
    • C07J1/0088—Substituted in position 17 alfa and 17 beta the substituent in position 17 alfa being an unsaturated hydrocarbon group
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J11/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J21/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C07J21/005—Ketals
    • C07J21/008—Ketals at position 17
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J33/00—Normal steroids having a sulfur-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C07J33/005—Normal steroids having a sulfur-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton spiro-condensed
    • C07J33/007—Cyclic thioketals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0005—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring the nitrogen atom being directly linked to the cyclopenta(a)hydro phenanthrene skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J43/00—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C07J43/003—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton not condensed

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
LU79036A 1977-02-10 1978-02-09 Steroides-11beta-substitues et procede de leur preparatio LU79036A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
NL7701384A NL7701384A (nl) 1977-02-10 1977-02-10 Werkwijze voor het bereiden van nieuwe steroiden van de oestraanreeks.

Publications (1)

Publication Number Publication Date
LU79036A1 true LU79036A1 (fr) 1978-06-26

Family

ID=19827952

Family Applications (1)

Application Number Title Priority Date Filing Date
LU79036A LU79036A1 (fr) 1977-02-10 1978-02-09 Steroides-11beta-substitues et procede de leur preparatio

Country Status (16)

Country Link
US (1) US4292251A (fr)
JP (1) JPS53101357A (fr)
AU (1) AU519916B2 (fr)
BE (1) BE863872A (fr)
CA (1) CA1109458A (fr)
DE (1) DE2805490A1 (fr)
DK (1) DK62278A (fr)
ES (2) ES466843A1 (fr)
FI (1) FI780424A7 (fr)
FR (1) FR2380300A1 (fr)
GB (1) GB1595661A (fr)
IE (1) IE46384B1 (fr)
LU (1) LU79036A1 (fr)
NL (1) NL7701384A (fr)
SE (1) SE7801539L (fr)
ZA (1) ZA78476B (fr)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3042136A1 (de) * 1980-11-03 1982-06-09 Schering Ag, 1000 Berlin Und 4619 Bergkamen Verfahren zur herstellung von 3 (beta), 7 (beta) -dihydroxy- (delta) (pfeil hoch)5(pfeil hoch) -steroiden
FR2528434B1 (fr) * 1982-06-11 1985-07-19 Roussel Uclaf Nouveaux 19-nor steroides substitues en 11b et eventuellement en 2, leur procede de preparation et leur application comme medicament
AU572589B2 (en) 1983-12-14 1988-05-12 Upjohn Company, The 11(alpha)-difluoromethyl and (e)-and (z)-11-fluoromethylene steroids
US4567000A (en) * 1984-08-31 1986-01-28 The Upjohn Company 11-Difluoromethylene steroids
DE3702383A1 (de) * 1987-01-23 1988-08-04 Schering Ag 11ss-alkinylestrene und -estradiene, deren herstellung und diese enthaltende pharmazeutische praeparate
FR2618783B1 (fr) * 1987-07-30 1991-02-01 Roussel Uclaf Nouveaux 17-aryle steroides, leurs procedes et des intermediaires de preparation comme medicaments et les compositions pharmaceutiques les renfermant
US5710144A (en) * 1993-02-08 1998-01-20 Akzo Nobel N.V. C-11 substituted steroids for treating menopausal complaints
US6037339A (en) 1993-02-08 2000-03-14 Akzo Nobel N.V. C-11 substituted steroids for treating menopausal complaints
ZA94715B (en) * 1993-02-08 1994-10-24 Akzo Nv Steroids for treating menopausal complaints
KR20010041698A (ko) * 1998-03-09 2001-05-25 악조 노벨 엔.브이. 신규 피임 키트
US20030083231A1 (en) * 1998-11-24 2003-05-01 Ahlem Clarence N. Blood cell deficiency treatment method
IL146284A0 (en) 1999-05-04 2002-07-25 Strakan Ltd Androgen glycosides and pharmaceutical compositions containing the same
DE102007027635A1 (de) 2007-06-12 2008-12-18 Bayer Schering Pharma Aktiengesellschaft 17ß-Cyano-19-androst-4-en-Derivat, dessen Verwendung und das Derivat enthaltende Arzneimittel
DE102007027637A1 (de) 2007-06-12 2008-12-18 Bayer Schering Pharma Aktiengesellschaft 17ß-Cyano-19-nor-androst-4-en-Derivat, dessen Verwendung und das Derivat enthaltende Arzneimittel
DE102007027636A1 (de) * 2007-06-12 2008-12-18 Bayer Schering Pharma Aktiengesellschaft 17ß-Cyano-18a-homo-19-nor-androst-4-en-Derivat, dessen Verwendung und das Derivat enthaltende Arzneimittel
DE102007063495A1 (de) 2007-12-29 2009-09-17 Bayer Schering Pharma Aktiengesellschaft 19-Nor-Steroidderivate mit einer 15α,16α-Methylengruppe und einem gesättigten 17,17-Spirolactonring, deren Verwendung sowie diese Derivate enthaltende Arzneimittel
DE102007063499A1 (de) 2007-12-29 2009-07-02 Bayer Schering Pharma Aktiengesellschaft Steroid-17,17-Lactol-Derivat, dessen Verwendung und das Derivat enthaltende Arzneimittel
DE102007063496A1 (de) 2007-12-29 2009-07-02 Bayer Schering Pharma Aktiengesellschaft 15,16-Methylen-17-(1'-propenyl)-17-3'-oxidoestra-4-en-3-on-Derivat, dessen Verwendung und das Derivat enthaltende Arzneimittel
DE102007063498A1 (de) 2007-12-29 2009-07-02 Bayer Schering Pharma Aktiengesellschaft 15,16-Methylen-steroid-17,17-Lactol-Derivat, dessen Verwendung und das Derivat enthaltende Arzneimittel
DE102007063500A1 (de) 2007-12-29 2009-07-02 Bayer Schering Pharma Aktiengesellschaft 17-(1'-Propenyl)-17-3'-oxidoestra-4-en-3-on-Derivat, dessen Verwendung und das Derivat enthaltende Arzneimittel
DE102007063501A1 (de) 2007-12-29 2009-07-02 Bayer Schering Pharma Aktiengesellschaft 15, 16-Methylen-17-hydroxy-19-nor-21-carbonsäure-Steroid y-Lacton-Derivat, dessen Verwendung und das Derivat enthaltende Arzneimittel
DE102007063503A1 (de) 2007-12-29 2009-07-02 Bayer Schering Pharma Aktiengesellschaft 17-Hydroxy-19-nor-21-carbonsäure-Steroid y-Lacton-Derivat, dessen Verwendung und das Derivat enthaltende Arzneimittel

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3299108A (en) * 1965-10-18 1967-01-17 Searle & Co 17alpha-alkynyl/alkenyl-13beta-alkyl-11-alkylgona-1, 3, 5 (10)-triene-3, 17beta-diols, ethers and esters thereof and intermediates thereto
US3346602A (en) * 1966-10-12 1967-10-10 Searle & Co 13beta-alkyl-11-alkylgona-1, 3, 5 (10)-trien-17-ones, ethers and esters thereof
US3465010A (en) * 1966-11-22 1969-09-02 Searle & Co 17 - (unsaturated hydrocarbon - substituted) 11,13beta - dialkylgon -4 - ene - 3,17beta-diols and esters thereof
US3377366A (en) * 1966-12-02 1968-04-09 Searle & Co 17alpha-alkynyl/alkenyl-11, 13beta-dialkylgon-5(10)-en-3-ones and esters thereof
GB1255345A (en) 1969-08-15 1971-12-01 Searle & Co 3-(3-OXO-11beta13beta-DIALKYL-17beta-HYDROXYGON-4-EN-17alpha-YL) PROPIONIC ACID gamma-LACTONE
US3755301A (en) * 1972-06-23 1973-08-28 Searle & Co Manufacture of 11-alkyl steroids
FI54128C (fi) * 1972-12-09 1978-10-10 Akzo Nv Foerfarande foer framstaellning av nya 11,11-alkylidensteroider ur oestran- och 19-norpregnanserien med foerbaettrad hormonell verkan
FR2235949B1 (fr) 1973-06-18 1978-03-17 Roussel Uclaf
NL7317358A (nl) * 1973-12-19 1975-06-23 Akzo Nv Nieuwe 11(beta)-alkylsteroiden van de oestraanreeks.
FR2377419A1 (fr) * 1977-01-13 1978-08-11 Roussel Uclaf Nouveaux derives steroides 11b-substitues 1,3,5 (10) trieniques, leur procede de preparation et leur application comme medicament

Also Published As

Publication number Publication date
DK62278A (da) 1978-08-11
IE46384B1 (en) 1983-05-18
FR2380300B1 (fr) 1981-05-08
FR2380300A1 (fr) 1978-09-08
ES475164A1 (es) 1979-06-16
IE780178L (en) 1978-08-10
JPS53101357A (en) 1978-09-04
SE7801539L (sv) 1978-08-11
ES466843A1 (es) 1979-06-01
DE2805490A1 (de) 1978-08-17
BE863872A (fr) 1978-08-10
GB1595661A (en) 1981-08-12
NL7701384A (nl) 1978-08-14
ZA78476B (en) 1978-12-27
CA1109458A (fr) 1981-09-22
AU3310378A (en) 1979-08-16
FI780424A7 (fi) 1978-07-11
AU519916B2 (en) 1982-01-07
US4292251A (en) 1981-09-29

Similar Documents

Publication Publication Date Title
FR2449699B1 (fr) Polyetherpolyamides et leur procede de preparation
FR2299362A1 (fr) Spheres creuses et procede de leur preparation
LU79036A1 (fr) Steroides-11beta-substitues et procede de leur preparatio
BE868571A (fr) Sucreries aerees et leur procede de preparation
BE849794A (fr) Derives de carbostyrile et leur procede de preparation
FR2331584A1 (fr) Poly (arylato-sulfones) et leur procede de preparation
BE869163A (fr) Thioethers basiques et leur procede de preparation
BE847090A (fr) 15-steroides, et leur procede de preparation
BE866660A (fr) Procede de preparation de n-alkyl-n-acyl-thienamycines et leur utilisation
BE838079A (fr) Derives de tetrahydroisoquinoleine et leur procede de preparation
BE865136A (fr) Composes de 2-phenoxy-5-trifluoromethylpyridine et leur procede de preparation
FR2301521A1 (fr) Nouvelles n-acyl-n-norsalutaridines et leur procede de preparation
BE832047A (fr) Procede de preparation de phosphorothioates et de phenylphosphonothioates
BE856220A (fr) Polyether-polyureides et procede de leur preparation
BE872294A (fr) Procede de preparation de 3-iodorifamycine s et de 3-bromorifamycine s
BE884652R (fr) Phenoxyalcoyl trialcoxysilanes et leur procede de preparation
FR2299865A1 (fr) Arylmethyl-1 imidazolidones-2 et leur procede de preparation
FR2347370A1 (fr) 7-amino-3-tetrazolyl substitue-thiomethyl-cephalosporines et leur procede de preparation
BE868027A (fr) Nouvelles pyridazinylhydrazones et leur procede de preparation
BE869407A (fr) 2-cyclopropyl-chromones substituees et procede pour leur preparation
FR2424281B1 (fr) Phenoxyalcoyl trialcoxysilanes et leur procede de preparation
BE846402A (fr) 4-hydroxymethyl-2-pyrrolidinones et leur procede de preparation
BE862066A (fr) Agents anti-rhinovirus et procede de leur preparation
FR2322870A1 (fr) Procede de preparation de phosphorothioates et de phenylphosphonothioates
FR2329267A2 (fr) Styrylamidines et leur procede de preparation