LU504643B1 - Embryo cryo-preservation transport device for reproductive laboratory - Google Patents
Embryo cryo-preservation transport device for reproductive laboratory Download PDFInfo
- Publication number
- LU504643B1 LU504643B1 LU504643A LU504643A LU504643B1 LU 504643 B1 LU504643 B1 LU 504643B1 LU 504643 A LU504643 A LU 504643A LU 504643 A LU504643 A LU 504643A LU 504643 B1 LU504643 B1 LU 504643B1
- Authority
- LU
- Luxembourg
- Prior art keywords
- fixedly connected
- box body
- insulation layer
- transport device
- embryo
- Prior art date
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- 230000001850 reproductive effect Effects 0.000 title claims abstract description 20
- 210000001161 mammalian embryo Anatomy 0.000 title claims description 30
- 238000005138 cryopreservation Methods 0.000 title claims description 19
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 claims abstract description 68
- 238000009413 insulation Methods 0.000 claims abstract description 49
- 239000007788 liquid Substances 0.000 claims abstract description 35
- 229910052757 nitrogen Inorganic materials 0.000 claims abstract description 34
- 230000017525 heat dissipation Effects 0.000 claims abstract description 10
- 238000007789 sealing Methods 0.000 claims description 16
- 230000007246 mechanism Effects 0.000 claims description 5
- 238000003890 embryo preservation Methods 0.000 abstract 1
- 210000002257 embryonic structure Anatomy 0.000 description 11
- 238000000034 method Methods 0.000 description 8
- 230000008569 process Effects 0.000 description 6
- 230000009471 action Effects 0.000 description 3
- 230000000694 effects Effects 0.000 description 3
- 238000005516 engineering process Methods 0.000 description 3
- 238000007710 freezing Methods 0.000 description 3
- 230000008014 freezing Effects 0.000 description 3
- 230000006378 damage Effects 0.000 description 2
- 238000002054 transplantation Methods 0.000 description 2
- 238000004017 vitrification Methods 0.000 description 2
- 206010033266 Ovarian Hyperstimulation Syndrome Diseases 0.000 description 1
- 208000031481 Pathologic Constriction Diseases 0.000 description 1
- 206010037660 Pyrexia Diseases 0.000 description 1
- 206010042573 Superovulation Diseases 0.000 description 1
- 208000027418 Wounds and injury Diseases 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000002357 endometrial effect Effects 0.000 description 1
- 230000008020 evaporation Effects 0.000 description 1
- 238000001704 evaporation Methods 0.000 description 1
- 239000007789 gas Substances 0.000 description 1
- 230000006872 improvement Effects 0.000 description 1
- 238000000338 in vitro Methods 0.000 description 1
- 208000014674 injury Diseases 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000027758 ovulation cycle Effects 0.000 description 1
- 238000004321 preservation Methods 0.000 description 1
- 230000036262 stenosis Effects 0.000 description 1
- 208000037804 stenosis Diseases 0.000 description 1
- 238000010257 thawing Methods 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N1/00—Preservation of bodies of humans or animals, or parts thereof
- A01N1/02—Preservation of living parts
- A01N1/0236—Mechanical aspects
- A01N1/0242—Apparatuses, i.e. devices used in the process of preservation of living parts, such as pumps, refrigeration devices or any other devices featuring moving parts and/or temperature controlling components
- A01N1/0252—Temperature controlling refrigerating apparatus, i.e. devices used to actively control the temperature of a designated internal volume, e.g. refrigerators, freeze-drying apparatus or liquid nitrogen baths
- A01N1/0257—Stationary or portable vessels generating cryogenic temperatures
Landscapes
- Physics & Mathematics (AREA)
- Thermal Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Mechanical Engineering (AREA)
- Health & Medical Sciences (AREA)
- Dentistry (AREA)
- General Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Environmental Sciences (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
The present invention discloses an embryo preservation transport device for reproductive laboratory, including a box body, an inner wall of the box body is fixedly connected to a first insulation layer, an interior side of the first insulation layer is provided with a condenser tube, an interior side of the box body is provided with a second insulation layer, at a bottom left side of the rear end of the box body is provided with a heat dissipation port, a right side at the top side of the hinge is fixedly connected to a box cover, an interior side of the second insulation layer is fixedly connected to a liquid nitrogen cabin, a top end of the support block is fixedly connected to a universal wheel. According to the present invention, the three insulation layers on the outside of the liquid nitrogen cabins prevent the transport device from leaking liquid nitrogen during transportation.
Description
Embryo cryo-preservation transport device for reproductive laboratory-/°°*°63
The present invention relates to the technical field of the low temperature transport, especially relates to the embryo cryo-preservation transport device for reproductive laboratory.
Background technology
Embryo cryo-preservation technology refers to a method in which embryos and frozen liquid are placed in a freezing tube, and human gametes and embryos at different stages can be allowed to stand still at extremely low temperatures through vitrification, and a method that can be stored in liquid nitrogen at -196 °C. In assisted reproductive technology, the number of embryos obtained in the conventional ovulation cycles, the number of embryos obtained greatly exceeds the number of transplants (1-2), and the excess embryos are frozen and stored that are used to freeze embryo transplantation, after the natural cycle or artificial cycle thawing, it is implanted into the uterine cavity, it will increase the chance of conception. It can be used in a super-ovulation cycle to obtain a large number of embryos with good quality, it can not be transferred all at once, and the excess embryos can be cryo-preservation. Patients with severe ovarian hyper stimulation syndrome, or those who are not suitable for embryo transfer in the treatment cycle due to endometrial thinning, polyps, fever, difficulty in cervical exposure, stenosis, etc., it can freeze the embryo, then the embryo resuscitation and transplantation will be carried out in the future natural cycle or artificial cycle. Our center can carry out gametes and the vitrification freezing of embryos at different stages.
In the daily work of the reproductive laboratory, the freezing transport process is often involved. Especially in the in vitro fertilization-embryo transfer operation, it is often necessary to send some embryos waiting for transfer from the operating room to the storage room. Because the embryo needs to be continuously in a frozen environment, the current main embryo transfer process is still the experimenter’s manual delivery of the liquid nitrogen box containing the embryo. In this process, due to the continuous evaporation of liquid nitrogen, the stable temperature environment of the embryo cannot be guaranteed, and if the liquid nitrogen is sprayed or overflowed during the delivery process, it will cause damage to the laboratory environment. The continuous cold air is dangerous to the transporter and the manual delivery efficiency is low.
Summary of the invention 17906663
An object of the present invention is to solve the shortcomings in the prior art, and proposes an embryo cryo-preservation transport device for reproductive laboratory.
In order to achieve the objects, the present invention adopts the following technical solutions: an embryo cryo-preservation transport device reproductive laboratory, including a box body, an inner wall of the box body is fixedly connected to a first insulation layer, an interior side of the first insulation layer is provided with a condenser tube, an interior side of the box body is provided with a second insulation layer, at a bottom left side of the rear end of the box body is provided with a heat dissipation port, a left side at the top end of the box body is fixedly connected to a hinge, a right side at the top side of the hinge is fixedly connected to a box cover, at a bottom end of the box cover is fixedly connected to a fixture block, around the bottom end of the box cover is fixedly connected to a sealing ring, an interior side of the second insulation layer is fixedly connected to a liquid nitrogen cabin, a top side of the liquid nitrogen cabin is provided with a plurality of grooves, a right end of the box cover is fixedly connected to a fastener, a top side at a right end of the box body is fixedly connected to a fixed block, a top end of the fixed block is rotated and connected to a wrench, a top end of the wrench is rotated and connected to a snap ring, four corners at a bottom end of the box body is fixedly connected to a support block, a top end of the support block is fixedly connected to a universal wheel.
As a further description of the above technical solutions: an outer wall of the second insulation layer is fixedly connected to a condenser tube, a rear end of the condenser tube is fixedly connected to a refrigerating machine.
As a further description of the above technical solutions: the refrigerating machine is located in the first insulation layer, the position of the refrigerating machine corresponds to the position of the heat dissipation port between the inner walls of the box body.
As a further description of the above technical solutions: a fixture block corresponds to the size of a top end port of the box body, a sealing ring corresponds to the size of the top end port of the box body.
As a further description of the above technical solutions: a left side at a top end of the liquid nitrogen cabin is fixedly connected to a rotation axis and an outer side of the rotation axis is rotated and connected to a insulation cover. 0506663
As a further description of the above technical solutions: a bottom end of the insulation cover is fixedly connected to a third insulation layer, and the size of the third insulation layer is matched with the size of the liquid nitrogen cabin hatch.
As a further description of the above technical solutions: an interior side of the fastener is connected to a snap ring in a sliding mode, the position of the fastener corresponds to the position of the fixed block.
As a further description of the above technical solutions: a manual self-locking mechanism is provided on the universal wheel.
The present invention has the following beneficial effects: 1. According to the present invention, the third insulation layer is rotated and connected to the liquid nitrogen cabin, and the first and second insulation layers in the box body are matched with the box cover through the liquid nitrogen cabin, the heat preservation and sealing of the whole transport device are strengthened to prevent the leakage of liquid nitrogen during transportation. 2. According to the present invention, through the condenser tube between the first protection layer and the second protection layer, under the work of the refrigerating machine, the whole transport device has been kept in a low temperature state, so as to avoid the direct contact of the staff with liquid nitrogen and injury, and at the same time under the action of the universal wheel to facilitate the movement of the whole device.
FIG.1 is a perspective view of an embryo cryo-preservation transport device for reproductive laboratory proposed by the present invention;
FIG.2 is an exploded view of an embryo cryo-preservation transport device for reproductive laboratory proposed by the present invention; and
FIG.3 is a sectional view of the box body of an embryo cryo-preservation transport device for reproductive laboratory proposed by the present invention.
Among them: 1. box body; 2. the first insulation layer; 3. condenser tube; 4. the second insulation layer; 5. refrigerating machine; 6. heat dissipation port; 7. hinge; 8. box cover; 81. fixture block; 9.sealing ring; 10. liquid nitrogen cabin; 11. groove; 12. fastener; 13. fixed block; 14.wrench; 15. snap ring, 078 16. support block; 17. universal wheel; 18. rotation axis; 19. insulation cover; 20. the third insulation layer.
The following will be combined with the attached drawings in the examples of the present invention, the technical solutions in the examples of the present invention will be clearly and completely described, it is clear that the described examples are only a part of the examples of the present invention, and not all of the examples. Based on the examples in the present invention, all other examples obtained by ordinary technicians in the field without making creative results, are belonged the scope of protection of the present invention.
In the description of the present invention, it should be noted that the orientation or position relationship indicated by the terms “center”, “top”, “bottom”, “left ”, “right”, “vertical”, “horizontal”, “inner”, “outer” and so on is based on the orientation or position relationship shown in the drawings, and are used only to facilitate and simplify the description of the present invention, rather than indicating or implying that the device or the element referred to must have a specific orientation, be constructed and operated in a specific orientation, therefore, it cannot be understood as a limitation of the present invention. The terms “first”, “second” and “third” are used only for describing purposes, and cannot be understood as indicating or implying the relative importance. In addition, unless expressly specified and limited, the terms “mounted”, “connected”, “be connected to” should be understood in a broad sense, for example, it can be a fixed connection, a detachable connection, an all-in-one connection, a mechanical connection, an electrical connection, a directly connection, an indirect connection through an intermediate medium, or a connection between the inside of two elements. For those ordinary skilled in the art, specific meanings of the above terms in the present invention can be understood on a case-by-case basis.
Referring to FIG.1-FIG.3, the present invention provides an example: an embryo cryo-preservation transport device for reproductive laboratory, including a box body 1, an inner wall of the box body 1 is fixedly connected to a first insulation layer 2, an interior side of the first insulation layer 2 is provided with a condenser tube 3, an interior side of the box body 1 is provided with a second insulation layer 4, the condenser tube 3 is located between the first insulation layer 2 and the second insulation layer 4, so as to ensure that the inner cavity of the 904643 whole transport device is continuously in a low temperature state, it not only maintains the low temperature environment in the process of embryo transport, but also reduces the volatilization of liquid nitrogen and saves costs, at a bottom left side of the rear end of the box body 1 is 5 provided with a heat dissipation port 6, the heat absorbed during the operation of the refrigerating machine 5 is dissipated from the heat dissipation port 6 outside the transport device, a left side at the top end of the box body 1 is fixedly connected to a hinge 7, a right side at the top side of the hinge 7 is fixedly connected to a box cover 8, at a bottom end of the box cover 8 is fixedly connected to a fixture block 81, around the bottom end of the box cover 8 is fixedly connected to a sealing ring 9, a left bottom end of the box cover 8 is rotated downward with hinge 7 as the center to make the bottom end of the box cover 8 is fixedly connected to the fixture block 81 into the box mouth at the top end of the box body 1, at this time, the sealing ring 9 is fixedly connected around the bottom end of the box cover 8 that is close to the top end of the box body 1 to achieve the sealing effect, it can ensure that the cold air and liquid nitrogen in the box body 1 do not leak, thus ensuring the personal safety of the operator, an interior side of the second insulation layer 4 is fixedly connected to a liquid nitrogen cabin 10, a top side of the liquid nitrogen cabin 10 is provided with a plurality of grooves 11, the frozen embryos are placed in groove 11 of liquid nitrogen cabin 10 by placing a sliding connection between the frozen embryo container and the inner side of groove 11, a right end of the box cover 8 is fixedly connected to a fastener 12, a top side at a right end of the box body 1 is fixedly connected to a fixed block 13, a top end of the fixed block 13 is rotated and connected to a wrench 14, a top end of the wrench 14 is rotated and connected to a snap ring 15, the wrench 14 is rotated upward at the right end of the fixed block 13 to make the snap ring 15 connected by the top end of the wrench 14 move upward, the snap ring 15 is stuck into the inside of the fastener 12 and then the wrench 14 is rotated downward to make the snap ring 15 and the fastener 12 tightly connected, this structure makes the box cover 8 and the box body] tightly connected to ensure that the box cover 8 will not open during the movement of the transport device at the same time, the sealing gasket is squeezed through the tight connection between the snap ring 15 and the fastener 12 to increase the sealing performance of the device, four corners at a bottom end of the box body 1 is fixedly connected to a support block 16, a top end of the support block 16 is fixedly connected to a universal wheel 17. 0506663
An outer wall of the second insulation layer 4 is fixedly connected to a condenser 3, a rear end of the condenser 3 is fixedly connected to a refrigerating machine 5, the refrigerating machine 5 is located in the first insulation layer 2, the position of the refrigerating machine 5 corresponds to the position of the heat dissipation port 6 between the inner walls of the box body 1, a fixture block 81 corresponds to the size of a top end port of the box body 1, a sealing ring 9 corresponds to the size of the top end port of the box body 1, a left side at a top end of the liquid nitrogen cabin 10 is fixedly connected to a rotation axis 18 and an outer side of the rotation axis 18 is rotated and connected to a insulation cover 19, a bottom end of the insulation cover 19 is fixedly connected to a third insulation layer 20, and the size of the third insulation layer 20 is matched with the size of the liquid nitrogen cabin 10 hatch, the third insulation layer 20 rotates on the rotating axis 18 that is fixedly connected to the right side of the top end of the liquid nitrogen cabin 10, and the third insulation layer 20 moves downward with the rotation axis 18 as the center of the circle until it is close to the top end of the liquid nitrogen cabin 10, an interior side of the fastener 12 is connected to a snap ring 15 in a sliding mode, the position of the fastener 12 corresponds to the position of the fixed block 13, a manual self-locking mechanism is provided on the universal wheel 17, due to there are many structures in the transport device, the weight of the transport device is larger, the universal wheel 17 at the bottom end of the support block 16 is fixedly connected at the bottom of the box body 1 that is used to realize the movement of the whole device, at the same time, under the action of the manual self-locking mechanism on the universal wheel 17, the stationary state of the transport device is locked to prevent the position of the device from drifting.
An operation principle: the frozen embryos are placed in groove 11 of liquid nitrogen cabin 10 by placing a sliding connection between the frozen embryo container and the inner side of groove 11, the third insulation layer 20 rotates on the rotating axis 18 that is fixedly connected to the right side of the top end of the liquid nitrogen cabin 10, and the third insulation layer 20 moves downward with the rotation axis 18 as the center of the circle until it is close to the top end of the liquid nitrogen cabin 10, at this time, the refrigerating machine 5 is turned on, when the refrigerating machine 5 works, the condenser tube 3 absorbs the hot gas in the transport device to achieve the effect of refrigerating, due to the condenser tube 3 is located between the first insulation layer 2 and the second insulation layer 4, so as to ensure that the inner cavity 5 904643 the whole transport device is continuously in a low temperature state, it not only maintains the low temperature environment in the process of embryo transport, but also reduces the volatilization of liquid nitrogen and saves costs, in addition, the heat absorbed during the operation of the refrigerating machine 5 is dissipated from the heat dissipation port 6 outside the transport device, a left bottom end of the box cover 8 is rotated downward with hinge 7 as the center to make the bottom end of the box cover 8 is fixedly connected to the card block 81 into the box mouth at the top end of the box body 1, at this time, the sealing ring 9 is fixedly connected around the bottom end of the box cover 8 that is close to the upper end of the box body 1 to achieve the sealing effect, it can ensure that the cold air and liquid nitrogen in the box body 1 do not leak, thus ensuring the personal safety of the operator, the wrench 14 is rotated upward at the right end of the fixed block 13 to make the snap ring 15 connected by the top end of the wrench 14 move upward, the snap ring 15 is stuck into the inside of the fastener 12 and then the wrench 14 is rotated downward to make the snap ring 15 and the fastener 12 tightly connected, this structure makes the box cover 8 and the box body 1 tightly connected to ensure that the box cover 8 will not open during the movement of the transport device at the same time, the sealing gasket is squeezed through the tight connection between the snap ring 15 and the fastener 12 to increase the sealing performance of the device, due to there are many structures in the transport device, the weight of the transport device is larger, the universal wheel 17 at the bottom end of the support block 16 is fixedly connected at the bottom of the box body 1 that is used to realize the movement of the whole device, at the same time, under the action of the manual self-locking mechanism on the universal wheel 17, the stationary state of the transport device is locked to prevent the position of the device from drifting.
Finally, it should be noted that the above mentioned is only a preferred example of the present invention, and is not used to limit the present invention. Despite the present invention is described in detail with reference to the above mentioned examples, for these skilled in the art, the technical solutions described in the above mentioned examples can be modified, or some of technical features can be replaced equivalently. Any modification, equivalent replacement, improvement, etc. made within the spirit and principles of the present invention should be included in the scope of protection of the present invention.
Claims (8)
1. An embryo cryo-preservation transport device reproductive laboratory, comprising a box body (1), characterized in that an inner wall of the box body (1) is fixedly connected to a first insulation layer (2), an interior side of the first insulation layer (2) is provided with a condenser tube (3), an interior side of the box body (1) is provided with a second insulation layer (4), at a bottom left side of the rear end of the box body (1) is provided with a heat dissipation port (6), a left side at the top end of the box body (1) is fixedly connected to a hinge (7), a right side at the top side of the hinge (7) is fixedly connected to a box cover (8), at a bottom end of the box cover (8) is fixedly connected to a fixture block (81), around the bottom end of the box cover (8) is fixedly connected to a sealing ring (9), an interior side of the second insulation layer (4) is fixedly connected to a liquid nitrogen cabin (10), a top side of the liquid nitrogen cabin (10) is provided with a plurality of grooves (11), a right end of the box cover (8) is fixedly connected to a fastener (12), a top side at a right end of the box body (1) is fixedly connected to a fixed block (13), a top end of the fixed block (13) is rotated and connected to a wrench (14), a top end of the wrench (14) is rotated and connected to a snap ring (15), four corners at a bottom end of the box body (1) is fixedly connected to a support block (16), a top end of the support block (16) is fixedly connected to a universal wheel (17).
2. The embryo cryo-preservation transport device for reproductive laboratory according to claim 1, characterized in that an outer wall of the second insulation layer (4) is fixedly connected to a condenser tube (3), a rear end of the condenser tube (3) is fixedly connected to a refrigerating machine (5).
3. The embryo cryo-preservation transport device for reproductive laboratory according to claim 2, characterized in that the refrigerating machine (5) is located in the first insulation layer (2), the position of the refrigerating machine (5) corresponds to the position of the heat dissipation port (6) between the inner walls of the box body (1).
4. The embryo cryo-preservation transport device for reproductive laboratory according to claim 1, characterized in that a fixture block (81) corresponds to the size of a top end port of the box body (1), a sealing ring (9) corresponds to the size of the top end port of the box body (1).
5. The embryo cryo-preservation transport device for reproductive laboratory according to claim 1, characterized in that a left side at a top end of the liquid nitrogen cabin (10) is fixedly 904645 connected to a rotation axis (18) and an outer side of the rotation axis (18) is rotated and connected to a insulation cover (19).
6. The embryo cryo-preservation transport device for reproductive laboratory according to claim 5, characterized in that a bottom end of the insulation cover (19) is fixedly connected to a third insulation layer (20), and the size of the third insulation layer (20) is matched with the size of the liquid nitrogen cabin (10) hatch.
7. The embryo cryo-preservation transport device for reproductive laboratory according to claim 1, characterized in that an interior side of the fastener (12) is connected to a snap ring (15) in a sliding mode, the position of the fastener (12) corresponds to the position of the fixed block (13).
8. The embryo cryo-preservation transport device for reproductive laboratory according to claim 1, characterized in that a manual self-locking mechanism is provided on the universal wheel (17).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| LU504643A LU504643B1 (en) | 2023-07-03 | 2023-07-03 | Embryo cryo-preservation transport device for reproductive laboratory |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| LU504643A LU504643B1 (en) | 2023-07-03 | 2023-07-03 | Embryo cryo-preservation transport device for reproductive laboratory |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| LU504643B1 true LU504643B1 (en) | 2024-01-11 |
Family
ID=89473756
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| LU504643A LU504643B1 (en) | 2023-07-03 | 2023-07-03 | Embryo cryo-preservation transport device for reproductive laboratory |
Country Status (1)
| Country | Link |
|---|---|
| LU (1) | LU504643B1 (en) |
-
2023
- 2023-07-03 LU LU504643A patent/LU504643B1/en active
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