LU101728B1 - Composition, nutritional supplements, composition as a nutritional supplement for children and method of manufacture - Google Patents

Abstract

The invention relates to a composition containing a pepper component, a curcumin-cyclodextrin mixture and a mixture of fruits, vegetables and spices.

Description

LU101728 î

PM-International AG September 12, 2018 |

15, Waistrooss |

5445 Schengen | LUXEMBOURG. Composition, Food Supplements, Composition as A Food Supplement for Children and Method of Manufacturing Description ;

The invention relates to a composition, a nutritional supplement, a | Composition as a dietary supplement for children and a method for

Manufacture of a composition, a food supplement or a Composition as a dietary supplement for children. 2nd

The use of food supplements, for example in sports or to promote health, is already known.

Dietary supplements are also suitable for supplementing an unbalanced diet.

In contrast to | conventional foods and beverages are nutritional supplements | usually a concentrate of nutritional supplements or other substances with a nutritional, physiological effect.

They are dosed in Form, in particular in the form of capsules, lozenges, tablets, effervescent tablets,

Powder bags, liquid ampoules and bottles with drip inserts, for inclusion in | measured small quantities.

Often contains a dietary supplement more than a certain substance, for example several vitamins and / or | Minerals in a predetermined ratio.

Some supplements also contain certain antioxidants.

Since in the manufacture of most

Dietary supplements containing synthetic compounds are used; the preparations often result in a manageable number of ingredients.

Little | speaks against the use of synthetic ingredients, however not used all the power of nature.

In particular, the large number | of various plant secondary metabolites and polyphenols not in the

Extent used as nature provides.

Herbal |

Secondary metabolites such as polyphenols have been shown to have numerous LU101728 | health promoting properties with synergistic effects. | Ultimately, the substances that the '

Consumer needs in a corresponding situation, for example the athlete É when exercising.

Ultimately, however, it is not only crucial which substances are provided, but also how they are provided)

. and to what extent the nutritional supplements succeed to the body and ultimately | the single cell of the human body.

This )

Bioavailability becomes more concentrated especially when administered | Dietary supplements viewed as in need of improvement. |

It is therefore an object of the present invention to provide a composition, a | Dietary supplements and a composition as

To provide food supplements for children, in which one or more: components together with a mixture of various herbal | Secondary Metabolites Synergistically Their Health Promoting | Can have an effect and at the same time the bioavailability of components 0 is improved.

Furthermore, a method is to be provided that such;

Compositions and food supplements, especially in homogeneous Ë mixing, enables.

According to the invention, this object is achieved by a composition according to claim 1 and a food supplement according to claim 10.

Looking at the

Composition as a dietary supplement for children will do this job solved by claim 11.

With a view to the process of producing a Composition, a dietary supplement or a composition | as a dietary supplement for children, this task is through claim 15 | solved. | The invention is preferably based on the idea of a composition | preferably containing a pepper component, a curcumin-cyclodextrin mixture | and a mixture of fruits, vegetables and spices. |

The mixture of fruits, vegetables and spices according to the invention contains Lu101728 | preferably concentrates and extracts of various plants and provides a | Variety of health-promoting secondary plant metabolites, vitamins and: polyphenols ready. A composition according to the invention can increase the bioavailability of the compounds contained in the composition.

This results in a composition that has a particularly health-promoting effect and supports a balanced diet particularly well. i Another advantage is that the composition is different; Food supplements can be added with little effort, whereby different nutritional supplements differ from the properties of Benefit composition. / Preferred embodiments of the invention are specified in the subclaims). ; The composition preferably also contains an algae component. | In preferred embodiments, the algae component comes from brown algae. / In certain embodiments, algae and / or algae parts, in particular | dried algae and / or algae parts, which represent the algae component.: In certain embodiments, the algae component is an algae powder or | a powder of algae, especially dried algae.

A powder from algae is in particular by grinding algae, in particular by grinding | dried seaweed. | In certain embodiments, the algae component is an algae extract.

A | Algae extract is obtained in particular by means of organic and / or aqueous | Solvent, optionally obtained under the influence of heat.

The extract is optional dried after extraction, In certain embodiments, the algae component comes from brown algae, | in particular, the algae component is a powder from brown algae. | Algae contain valuable and natural organic substances and minerals. |

The composition preferably also contains an extract from the ginger LU101728 (Zingiber officinale). It is preferably an extract from the ginger rhizome (Zingiber officinale).

A ginger extract contains valuable and natural organic substances. In addition, a ginger extract is a bioenhancer that increases the bioavailability of; Components of the composition increases. / The pepper component is preferably an extract from the pepper (Piper nigrum), ı in particular piperine. ; A pepper extract or piperine increases the bioavailability of the components; the composition increased. ; The curcumin-cyclodextrin mixture is preferably a curcumin-cyclodextrin; Complex. Curcumin-cyclodextrin | is very particularly preferably Mixture around a curcumin-gamma-cyclodextrin complex. ! With such a design, curcumin can be absorbed particularly effectively; will and work. ; In preferred embodiments, the mixture of fruits, vegetables and | Spices | an extract from green tea (Camellia sinensis), in particular from leaves of the | green teas, and; a concentrate from broccoli (Brassica oleracea italica), in particular from Broccolis seeds, sprouts and / or sprouts, and a concentrate from broccoli (Brassica oleracea italica), in particular from Florets and / or stems of Broccolis, and | an onion extract (Allium cepa, especially Allium cepa alliaceae), especially from the onion of the onion, and | an extract from the apple (Malus domestica), in particular from the apple fruit, | In particular from peels of apple fruit, and / an extract from acerola (Malpighia glabra, in particular Malpighia glabra | linne), in particular from the fruit of acerola, and | a concentrate from the tomato (Lycopersicon esculentum), in particular from the | Fruit of the tomato, and | a concentrate from the turmeric (Curcuma longa), especially from the roots of the Lu + 101728 | Turmeric, and: a concentrate from garlic (Allium sativum), especially from the clove of garlic, and} a concentrate from basil (Ocimum basilicum), especially from leaves of basil, and / a concentrate from oregano (Origanum vulgare) , especially from leaves of Oregano, and / a concentrate from the cinnamon tree (Cinnamonum cassia), especially from the bark (without cork) of the cinnamon tree, and. a concentrate from the carrot (Dacus carota, especially Dacus carota sativa)! in particular from the root of the carrot, and a concentrate from the elder (Sambucus nigra), in particular from the fruit of the elder, and an extract from the currant (Ribes), in particular the black one; Currant (Ribes nigrum), especially from the fruit of the black one. Currant, and a concentrate from the blueberry (vaccinium), in particular from the fruit of the blueberry, and; a concentrate from the raspberry (Rubus idaeus), especially from the fruit of the | Raspberry, and | a concentrate from the blackberry (Rubus spp.), especially from the fruit of | Blackberry, and | a concentrate from the apple (Aronia, especially Aronia melanocarpa), | especially from the fruit of the apple, and a concentrate from spinach (Spinacia oleracea), particularly from leaves of spinach, and a concentrate from cherry (Prunus avium), especially from cherry fruit, and a concentrate from Brussels sprouts (Brassica oleracea gemmifera), especially from florets of Brussels sprouts. ! It cannot be completely ruled out that instead of individual concentrates or extracts in this list, concentrates or extracts from other, in particular ene-related, plants and other parts of plants can also be used to LU101728 | to achieve a similar technical effect. :

In certain embodiments, the mixture of fruits, vegetables and |

Spices ê an extract from green tea (Camellia sinensis), especially from leaves of the | green teas, and / or;

a concentrate from broccoli (Brassica oleracea italica), in particular from l seeds, germs and / or sprouts of broccoli, and / or:

a concentrate from broccoli (Brassica oleracea italica), in particular from Broccoli florets and / or stems, and / or | an onion extract (Allium cepa, especially Allium cepa alliaceae), especially from the bulb of the bulb, and / or | an extract from the apple (Malus domestica), especially from the apple fruit;

in particular from peels of apple fruit, and / or | an extract from acerola (Malpighia glabra, in particular Malpighia glabra | linne), in particular from the fruit of acerola, and / or | a concentrate from tomato (Lycopersicon esculentum), in particular from Fruit of tomato, and / or;

a concentrate from the turmeric (Curcuma longa), especially from the root of the | Turmeric, and / or a concentrate from garlic (Allium sativum), especially from Clove of garlic, and / or | a concentrate from basil (Ocimum basilicum), in particular from leaves of basil, and / or | a concentrate from the oregano (Origanum vulgare), in particular from leaves of the Oregano, and / or | a concentrate from the cinnamon tree (Cinnamonum cassia), in particular from the Bark (without cork) of the cinnamon tree, and / or | a concentrate from the carrot (Dacus carota, especially Dacus carota sativa), | in particular from the root of the carrot, and / or | a concentrate from the elderberry (Sambucus nigra), in particular from the fruit | of the elderberry, and / or | an extract from the currant (Ribes), in particular the black LU101728 Ë currant (Ribes nigrum), especially from the fruit of the black | Currant, and / or | a concentrate from the blueberry (vaccinium), in particular from the fruit of a blueberry, and / or | a concentrate from the raspberry (Rubus idaeus), in particular from the fruit of the É raspberry, and / or ‘a concentrate from the blackberry (Rubus spp.), in particular from the fruit of the | Blackberry, and / or L a concentrate from the apple (Aronia, especially Aronia melanocarpa), | in particular from the fruit of the apple, and / or | a concentrate from spinach (Spinacia oleracea), particularly from leaves of spinach, and / or | a concentrate from the cherry (Prunus avium), in particular from the cherry fruit; and / or | a concentrate from Brussels sprouts (Brassica oleracea gemmifera), in particular from Rose cabbage florets. | The term "extract" (preferred with the exception of algae extract) denotes in | Within the scope of this patent application a dried extract from the corresponding | Parts of plants, the extract preferably using ethanol and water and | is obtained with a drug extract ratio between 90: 1 and 15: 1.

A . In the context of this patent application, “concentrate” means a drained | Product from corresponding plant parts.

Fruit extracts and concentrates, Leaves, onions, bark (without cork), roots, rhizomes, tubers, seeds, germs, | Depending on the type of plant, sprouts, florets and stems offer a high content of valuable vegetable secondary metabolites such as polyphenols.

Basically, | one thought in making several extracts and concentrates from different | Provide plant species and parts in order to ensure the highest possible content and before | all the greatest possible diversity of plant secondary metabolites and polyphenols | to provide.

Therefore, a large number of extracts and concentrates are from different plant parts of different plant species preferred.

Polyphenols | are aromatic compounds that have two or more directly attached to an aromatic one; Contain ring bound hydroxyl groups and to the vegetable |

8 |

Secondary metabolites can be expected.

Polyphenols have various health-promoting effects, in particular some polyphenols. antioxidant. |

In preferred embodiments, 100 g of the composition contain 10 mg to 5000 mg, preferably 50 mg to 4000 mg, of the pepper component, 20 mg to 1000,

mg, preferably 80 mg to 400 mg, of the curcumin-cyclodextrin mixture, and 50 mg

up to 1000 mg, preferably 100 mg to 500 mg, of the mixture of fruits, vegetables and spices.

In addition, 100 g of the composition can optionally contain 1 mg | to 1000 mg, preferably 5 mg to 60 mg, of the extract from the ginger (Zingiber | officinale) and / or 5 mg to 500 mg, preferably 10 mg to 100 mg, of the Contain algae component. a

In preferred embodiments, the composition further contains one or more components selected from: | - Vitamin C, preferably 500 mg to 2000 mg per 100 g of composition; ;

Niacin, preferably 100 mg to 800 mg per 100 g of composition; |

Caffeine, preferably 50 mg to 500 mg per 100 g of composition; ;

- Alpha-tocopheryl acetate, preferably 20 mg to 300 mg per 100 g |

Composition; | Pantothenic acid, preferably 20 mg to 100 mg per 100 g Composition; |

Pyridoxine, preferably 5 mg to 60 mg per 100 g of composition; |

Thiamine, preferably 5 mg to 60 mg per 100 g of composition; |

Riboflavin, preferably 4 mg to 40 mg per 100 g of composition; | Cyanocobolamine, preferably 4 µg to 20 µg per 100 g of composition; |

Folic acid, preferably 0.5 mg to 5 mg per 100 g of composition; |

- Biotin, preferably 0.5 mg to 5 mg per 100 g of composition; |

Beta-carotene, preferably 4 mg to 30 mg per 100 g of composition; |

- Selenium-enriched yeast, preferably 10 mg to 500 mg per 100 g | Composition |

Gum arabic, preferably 10 g to 30 g per 100 g of composition; |

- Vegetable fibers, preferably from oats, peas, rice and apple, preferred)

10 g to 25 g per 100 g of composition; |

- Pectin and / or guar gum, preferably a total of 1 g to 6 g; LU101728 | Guarana extract, preferably 1 g to 3 g per 100 g of composition; ) - Lactic acid cultures (Lactobacillus acidophilus, Lactobacillus reuteri); preferably 0.1 g to 1 g per 100 g of composition; | Inulin, preferably 0.1 g to 1 g per 100 g of composition; ; Grape seed extract, preferably 1 mg to 20 mg per 100 g Composition. | In preferred embodiments, the composition further contains one or | several components selected from:] - Citric acid, preferably 1 g to 5 g per 100 g of composition; .

Fructose, preferably 20 g to 70 g per 100 g of composition; | - Beetroot puiver (concentrate of the beetroot juice, maltodextrin and ‘citric acid), preferably 0.1 g to 2 g per 100 g of composition; ; - Multi enzyme complex of amylase, lactase, protease, cellulase, lipase, | preferably 0.1 g to 1 g per 100 g of composition; | - Steviol glycosides, preferably 0.01 g to 0.5 g per 100 g of composition. | In preferred embodiments, the composition is in the form of a powder. In | In preferred embodiments, the composition is in powder form in capsules Bags or cans, especially in bags. The composition is very particularly preferably in the form of powder in individual doses in bags. In certain embodiments, the composition is suitable for production an aqueous solution in water. In certain embodiments, | the composition for making a suspension in water. | The invention is also based on the idea of a nutritional supplement specify that contains a composition according to the invention. | | Advantages and embodiments of the food supplement are discussed in the Advantages and embodiments of the composition referenced. | In preferred embodiments, the food supplement is in the form of powder in front. In preferred embodiments, the nutritional supplement is as |

Powder in capsules, sachets or cans, especially in sachets.

Quite | (191728 | the nutritional supplement is particularly preferably in powder form in individual doses; in bags.] In certain embodiments, the nutritional supplement is suitable for the preparation of an aqueous solution in water.

In certain embodiments | the food supplement is suitable for the production of a suspension in | Water. | The invention is also based on the idea of a composition as; To provide food supplements for children. The invention is preferably based on the idea of specifying a composition as: Dietary supplement for children, the composition | preferably a pepper component, a curcumin-cyclodextrin mixture and a | Mixture of fruits, vegetables and spices. | In other words, a composition is to be provided which is similar | Has effects and advantages as the composition described above, however in their composition specifically to the needs and Sensitivities of children.

Explanations and descriptions to date on the composition according to the invention and its advantages | therefore also apply to the composition as a dietary supplement for 7 children, unless the contrary follows from the following. | The pepper component is preferably an extract from the pepper (Piper nigrum), especially piperine. | With a pepper extract or

Piperine increases the bioavailability of the components of a food supplement. | The curcumin-cyclodextrin mixture is preferably a curcumin-cyclodextrin | Complex.

The curcumin-cyclodextrin / mixture is very particularly preferably a curcumin-gamma-cyclodextrin complex.

Such curcumin | Gamma-cyclodextrin complexes are commercially available.

With such a training, curcumin can be absorbed particularly effectively will and work. |

In preferred embodiments, the mixture of fruits, vegetables and LU101728 contains |

Spices an extract from green tea (Camellia sinensis), in particular from leaves of green tea, and a concentrate from broccoli (Brassica oleracea italica), in particular from

Broccolis seeds, sprouts and / or sprouts, and '

a concentrate from broccoli (Brassica oleracea italica), in particular from;

Broccoli florets and / or stems, and | an onion extract (Allium cepa, especially Allium cepa alliaceae),:

in particular from the onion of the onion, and an extract from the apple (Malus domestica), in particular from the apple fruit;

in particular from peels of apple fruit, and an extract from acerola (Malpighia glabra, in particular Malpighia glabralinne), in particular from the fruit of acerola, and;

a concentrate from the tomato (Lycopersicon esculentum), especially from:

Fruit of tomato, and;

a concentrate from the turmeric (Curcuma longa), especially from the root of the ı

Turmeric, and:

a concentrate from the garlic (Allium sativum), especially from the;

Clove of garlic, and /

a concentrate from basil (Ocimum basilicum), in particular from leaves of basil, and | a concentrate from oregano (Origanum vulgare), in particular from leaves of

Oregano, and | a concentrate from the cinnamon tree (Cinnamonum cassia), especially from the

Bark (without cork) of the cinnamon tree, and | a concentrate from the carrot (Dacus carota, especially Dacus carota sativa), | especially from the root of the carrot, and | a concentrate from elderberry (Sambucus nigra), especially from the fruit | of elder, and | an extract from currant (Ribes), especially black |

Currant (Ribes nigrum), especially from the fruit of the black | Currant, and

YY gagged aaaa concentrate from the blueberry (vaccinium), especially from the fruit of LU101728 | Blueberry, and | a concentrate from the raspberry (Rubus idaeus), especially from the fruit of: raspberry, and; a concentrate from the blackberry (Rubus spp.), in particular from the fruit of: blackberry, and; a concentrate from the apple berry (Aronia, especially Aronia melanocarpa); especially from the fruit of the apple, and a concentrate from spinach (Spinacia oleracea), particularly from leaves spinach, and; a concentrate from the cherry (Prunus avium), in particular from the cherry fruit, | a concentrate from the Brussels sprouts (Brassica oleracea gemmifera), in particular from; Rose sprouts. | It cannot be completely ruled out that instead of individual concentrates or extracts A in this list it is also possible to use concentrates or extracts from other, in particular related, plants and other parts of plants in order to | to achieve a similar technical effect. ) In certain embodiments, the mixture of fruits, vegetables and A spices | an extract from green tea (Camellia sinensis), in particular from leaves of the | green teas, and / or | a concentrate from broccoli (Brassica oleracea italica), in particular from Broccoli seeds, sprouts and / or sprouts, and / or | a concentrate from broccoli (Brassica oleracea italica), in particular from Broccoli frills and / or stems, and / or | an onion extract (Allium cepa, especially Allium cepa alliaceae), in particular from the onion of the onion, and / or) an extract from the apple (Malus domestica), in particular from the apple fruit, | in particular from peels of apple fruit, and / or; an extract from acerola (Malpighia glabra, in particular Malpighia glabra | linne), in particular from the fruit of acerola, and / or | a concentrate from tomato (Lycopersicon esculentum), in particular from LU101728 fruit of tomato, and / or | a concentrate from the turmeric (Curcuma longa), in particular from the root of the a turmeric, and / or 0 a concentrate from the garlic (Allium sativum), in particular from the î garlic clove, and / or | a concentrate from the basil (Ocimum basilicum), in particular from leaves 3 of the basil, and / or | a concentrate from the oregano (Origanum vulgare), in particular from leaves of the Oregano, and / or | a concentrate from the cinnamon tree (Cinnamonum cassia), especially from the | Bark (without cork) of the cinnamon tree, and / or.

a concentrate from the carrot (Dacus carota, in particular Dacus carota sativa), in particular from the root of the carrot, and / or É a concentrate from the elder (Sambucus nigra), in particular from the fruit of elder, and / or | an extract from the currant (Ribes), especially the black one | Currant (Ribes nigrum), in particular from the fruit of the black f currant, and / or É a concentrate from the blueberry (Vaccinium), in particular from the fruit of the | Blueberry, and / or; a concentrate from the raspberry (Rubus idaeus), especially from the fruit of the | Raspberry, and / or 0 a concentrate from the blackberry (Rubus spp.), Especially from the fruit of the; Blackberry, and / or | a concentrate from the apple (Aronia, especially Aronia melanocarpa), | in particular from the fruit of the apple, and / or | a concentrate from spinach (Spinacia oleracea), particularly from leaves of spinach, and / or | a concentrate from the cherry (Prunus avium), in particular from the cherry fruit, | and / or | a concentrate from Brussels sprouts (Brassica oleracea gemmifera), in particular from Rose cabbage florets,

In preferred embodiments, 100 g of the composition contain as LU101728 | Nutritional supplements for children; - 10 mg to 5000 mg, preferably 50 mg to 4000 mg, the | Pepper component, 0-4 mg to 300 mg, preferably 8 mg to 60 mg, of curcumin-cyclodextrin; - 50 mg to 1000 mg, preferably 100 mg to 500 mg, of the mixture of | Fruits, vegetables and spices. .

In preferred embodiments, the composition also contains one or more components as food supplements for children selected from: | - Vitamin C, preferably 500 mg to 2000 mg per 100 g; | - Niacin, preferably 50 mg to 600 mg per 100 g; 0 - alpha-tocopheryl acetate, preferably 80 mg to 300 mg per 100 g; É - pantothenic acid, preferably 50 mg to 100 mg per 100 g; | Pyridoxine, preferably 5 mg to 40 mg per 100 g; | Thiamine, preferably 5 mg to 50 mg per 100 g; | - Riboflavin, preferably 4 mg to 40 mg per 100 g; ; Cyanocobolamine, preferably 10 µg to 50 µg per 100 g; | Folic acid, preferably 0.5 mg to 3 mg per 100 g; .

- Biotin, preferably 0.2 mg to 1 mg per 100 g; | Beta-carotene, preferably 10 mg to 50 mg per 100 g; | - Chromium picolinate and / or chromium trichloride, each preferably from 0.5 mg to 5 mg per 100 g; ; Yeast enriched with selenium, preferably 50 to 400 mg per 100 g; ; Zinc gluconate, preferably 100 mg to 500 mg per 100 g; | Copper (II) gluconate, preferably 20 mg to 80 mg per 100 g; | Cholecalciferol, preferably 50 pg to 250 µg per 100 g; | Trimagnesium citrate, preferably 3 g to 11 g per 100 g; | Calcium hydrogen phosphate, preferably 0.5 g to 3 g per 100 g; | Cacium lactate, preferably 0.2 g to 1.0 g per 100 g; | Milk mineral concentrate, preferably 3 g to 15 g per 100 g; | - Inulin, preferably 40 g to 80 g per 100 g. | In preferred embodiments, the composition contains as | Dietary supplements for children also one or more components selected from: |

Citric acid, preferably 3 g to 11 g per 100 g; LU101728 | - Steviol glycosides, preferably 0.01 g to 1.0 g per 100 g. | In preferred embodiments, the composition contains as; Food supplements for children no algae component and no extract; from the ginger. | Another object of the invention is to provide a method for producing a A composition, a food supplement or a composition; to be indicated as a dietary supplement for children. The method comprises: 0 - Providing in a vessel and stirring Ë o the pepper component,} o the curcumin-cyclodextrin mixture, | o optionally the extract from the ginger (Zingiber officinale),.

o optionally the algae component and A o the mixture of fruits, vegetables and spices; ’- adding additional components and stirring to create an intermediate product to get | wherein the addition of at least one component preferably a) É in portions in subsets of a total amount of the component and | interrupted by stirring or b) continuously carried out with stirring; | - Filling the intermediate product in cans, bags or capsules. Ë The provision and addition is preferably such that the pepper component | in 10 mg to 5000 mg, preferably 50 mg to 4000 mg, per 100 g of intermediate product is present. | The provision and addition is preferably carried out in such a way that the mixture of | Fruits, vegetables and spices in 50 mg to 1000 mg, preferably 100 mg to 500 | mg, is present per 100 g of intermediate. | The provision and addition is optionally carried out such that the intermediate product | per 100 g 1 mg to 1000 mg, preferably 5 mg to 60 mg, of the extract from the Contains ginger (Zingiber officinale),

16 |

LU101728

The provision and addition is optionally carried out in such a way that the intermediate product contains per mg of 5 mg to 500 mg, preferably 10 mg to 100 mg, of the algae component. |

In the production of a composition or a food supplement: the provision and addition is preferably carried out in such a way that the curcumin: cyclodextrin mixture is present in 20 mg to 1000 mg, particularly preferably 80 mg to 400 mg, per 100 g of intermediate product.

When making a |

Composition as a dietary supplement for children is provided and preferably added such that the curcumin-cyclodextrin mixture in 4 mg /

up to 300 mg, particularly preferably 8 mg to 60 mg, per 100 g of intermediate product '. |

The algae component and the extract from the ginger are for the | Composition preferred optional.

For the composition as / food supplements for children, the algae component and the extract are from /

not intended for the ginger. |

The addition of at least one component is preferably carried out in portions in / portions of a total amount of the component and interrupted by stirring / or continuously with stirring. In other words, at least one | Component not added all at once, but in such a way that it can gradually mix with the other components.

This is especially for |

Components with a large proportion by weight, e.g.

Fructose or inulin, relevant. | This ensures efficient mixing and a homogeneous product become. |

The invention is explained in more detail below using an exemplary embodiment. |

| In an example of the composition according to the invention, 100 g of the | Composition 1000 mg piperine, 130 mg curcumin-gamma-cyclodextrin | Complex, 20 mg of an extract from the ginger (Zingiber officinale), 33 mg of an à

Powder from brown algae and 250 mg of a mixture of fruits, vegetables and LU101728 | Spices. | The mixture of fruits, vegetables and spices contains an extract of | Green tea leaves (Camellia sinensis), a concentrate of broccoli sprouts (Brassica oleracea italica), an extract from the onion of the onion (Allium cepa), an extract from the peel of the apple fruit (Malus domestica), an extract from the | Acerola fruit (Malpighia glabra), a concentrate of tomato fruit (Lycopersicon esculentum), a concentrate from florets and / or stems of / Broccolis (Brassica oleracea italica), a concentrate from the roots of the turmeric; (Curcuma longa), a concentrate from the clove of garlic (Allium sativum), a | Concentrate from basil leaves (Ocimum basilicum), a concentrate from | Oregano leaves (Origanum vulgare), a concentrate from the bark (without cork) of Cinnamon tree (Cinnamonum cassia), a concentrate from the root of the carrot (Dacus carota), a concentrate from the elderberry (Sambucus nigra), | an extract from the fruit of the currant (Ribes), a concentrate from the Blueberry fruit (Vaccinium), a concentrate of raspberry fruit (Rubus idaeus), a concentrate from the blackberry fruit (Rubus spp.), A | Apple fruit concentrate (aronia), a concentrate of spinach leaves (Spinacia oleracea), a concentrate from the cherry fruit (Prunus avium), a | Extract from the fruit of the blueberry (Vaccinium) and a concentrate from florets of the Brussels sprouts (Brassica oleracea gemmifera). To a large extent, the mixture of fruits, vegetables and spices contains an extract from green tea leaves (approx. 30% by weight), a concentrate from broccoli sprouts (approx. 10% by weight), an extract from the onion the onion (approx. 9% by weight), an extract from peel of the apple fruit (approx. 9% by weight), an extract) from the fruit of the acerola (approx. 4% by weight), a concentrate from the Tomato fruit (approx. 4% by weight) and a concentrate (approx. 4% by weight) from florets and / or stems of broccoli.

The remaining constituents are present in 0.1% to 3.5% by weight.

Various other compositions and nutritional supplements can also be produced with the composition according to the invention, TTT TTT Tse RR, all of which benefit significantly from the health-promoting and absorption-increasing LU101728 properties of the composition according to the invention. Thus, 100 g of the composition of this example also contain: Vitamin C, 1000 mg; | - niacin, 340 mg; - caffeine, 200 mg; - alpha tocopheryl acetate, 20 mg; - pantothenic acid, 60 mg; - pyridoxine, 20 mg; Thiamine, 14 mg; - riboflavin, 16 mg; Cyanocobolamine, preferably 10 pg; - folic acid, 2.0 mg; : - Biotin, 1.5 mg; - beta carotene, 13 mg; - Selenium-enriched yeast, 91 mg; Citric acid, 2.6 g; - gum arabic, 20 g; - Vegetable fibers from oats, peas, rice and apple, 17 g; - pectin, 1 g; - guar gum, 3 g; - guarana extract, 3 g; - Beetroot powder (concentrate of the beetroot juice, maltodextrin and citric acid), 0.7 g; - Lactic acid cultures (Lactobacillus acidophilus, Lactobacillus reuteri), 0.3 g; - multi-enzyme complex of amylase, lactase, protease, cellulase, lipase, 0.3 g; Inulin, 0.3 g; - steviol glycosides, 0.1 g; - grape seed extract 6 mg; - fructose, ad 100 g.

TT EE

This example also describes a nutritional supplement that contains this LU101728] composition.

In this exemplary embodiment, the composition is in the form of a powder in sachets in front.

In an example of the composition according to the invention as | Dietary supplements for children contain 100 g of the composition as; Dietary supplement for children 1000 mg piperine, 14 mg curcumin-gamma | Cyclodextrin complex, and 270 mg of a mixture of fruits, vegetables and | Spices. : The mixture of fruits, vegetables and spices contains an extract from; Green tea leaves (Camellia sinensis), a concentrate of broccoli sprouts. (Brassica oleracea italica), an extract of the onion of the onion (Allium cepa), an extract from apple fruit peel (Malus domestica), an extract from the Fruit of the acerola (Malpighia glabra), a concentrate from the fruit of the tomato! (Lycopersicon esculentum), a concentrate made from ruffles and / or stems of | Broccolis (Brassica oleracea italica), a concentrate from the root of the turmeric: (Curcuma longa), a concentrate from the toe of garlic (Allium sativum), a | Concentrate from basil leaves (Ocimum basilicum), a concentrate from oregano leaves (Origanum vulgare), a concentrate from the bark (without cork) of | Cinnamon tree (Cinnamonum cassia), a concentrate from the root of the carrot (Dacus carota), a concentrate from the elderberry (Sambucus nigra), | an extract from the fruit of the currant (Ribes), a concentrate from the Blueberry fruit (Vaccinium), a concentrate of raspberry fruit (Rubus idaeus), a concentrate from the blackberry fruit (Rubus spp.), A | Apple fruit concentrate (aronia), a concentrate of spinach leaves (Spinacia oleracea), a concentrate from the cherry fruit (Prunus avium), an i extract from the fruit of the blueberry (Vaccinium) and a concentrate from rose / Brussels sprouts (Brassica oleracea gemmifera). | For the most part, the mixture of fruits, vegetables and spices contains a | Green tea leaf extract (approx. 30% by weight), a concentrate of sprouts of broccoli (approx. 10% by weight), an extract from the onion of the onion (approx. 9% by weight |

%), an extract from peels of apple fruit (approx. 9% by weight), an extract from LU101728 | Fruit of the acerola (approx. 4% by weight), a concentrate from the fruit of the tomato (approx. 4:% by weight) and a concentrate (approx. 4% by weight) made from ruffles and / or stems of the 1st Broccolis.

The remaining constituents are present in 0.8% by weight to 3.0% by weight.

Only Ëa concentrate from florets of rose cabbage and an extract from the fruit of Li blueberries are added to the mixture of fruits, vegetables and spices in smaller quantities (0.1% by weight to 0.3% by weight). : Furthermore, 100 g of this exemplary composition contain as:

Food supplements for children: - Vitamin C, 860 mg; /

- niacin, 214 mg; 3rd

- alpha tocopheryl acetate, 143 mg; )

- pantothenic acid, 72 mg; |

- pyridoxine, 23 mg; | - thiamine, 20 mg; |

- riboflavin, 19 mg; |

- cyanocobolamine, 29 µg; |

- folic acid, 2 mg; )

- biotin, 0.4 mg; | - beta carotene, 29 mg; ;

- chromium picolinate, 4 mg; |

- Selenium-enriched yeast, 120 mg; à

- zinc gluconate, 265 mg; |

Copper (ID) gluconate, 46 mg; | - Cholecalciferol, 107 µg |

- citric acid, 7 g; |

Trimagnesium citrate, 7 g; |

Calcium hydrogen phosphate, 1.3 g; |

- cacium lactate, 0.6 g; | - steviol glycosides, 0.4; |

- milk mineral concentrate, 7 g; |

- Inulin, ad 100 g. |

21 | This example describes a composition according to the invention as LU101728 | Dietary supplement for children, In this embodiment, the | Composition as a dietary supplement in the form of a powder in a Can before. | Finally, a method according to the invention for producing a composition according to the invention will be described by way of example. The process includes:; - Providing in a vessel and stirring | o 1000 mg extract from the pepper, | o 130 mg of the curcumin-cyclodextrin mixture, | o 20 mg of the extract from the ginger (Zingiber officinale),.

o 33 mg powder from brown algae and = o 250 mg of the mixture of fruits, vegetables and spices; | - Add 1 g of vitamin C and 5 g of fructose as additional | Components and stirring. After homogenization by stirring 1, a further 15 g of fructose are added and stirring is continued. After | further homogenization by stirring, a further 15 g of 7 fructose are added and stirring is continued. Then the difference becomes 100 g | added in the form of fructose and further homogenized by stirring. È The powder obtained is filled into bags. É The process ensures efficient mixing and a homogeneous product]. |

Claims (15)

Claims LU101728 | 1. Composition containing | o a pepper component, | o a curcumin-cyclodextrin mixture and | o a mixture of fruits, vegetables and spices. | 2. Composition according to claim 1, further comprising a / algae component, preferably an algae component from brown algae,: preferably a powder from brown algae. / 3. Composition according to one of the preceding claims, wherein the | Composition contains an extract of the ginger (Zingiber officinale). | 4 Composition according to one of the preceding claims, wherein the | Pepper component is an extract from the pepper (Piper nigrum), in particular / piperine. 5. Composition according to one of the preceding claims, wherein the | Curcumin-cyclodextrin mixture is a curcumin-cyclodextrin complex, preferably a curcumin-gamma-cyclodextrin complex. / 6. The composition according to any one of the preceding claims, wherein the mixture | from fruit, vegetables and spices an extract from green tea (Camellia | sinensis), a concentrate from broccoli (Brassica oleracea italica), a | Onion extract (Allium cepa), an apple extract (Malus | domestica), an acerola extract (Malpighia glabra), a tomato concentrate (Lycopersicon esculentum), a turmeric concentrate (Curcuma longa), a concentrate from the garlic (Allium sativum), a concentrate from the basil (Ocimum basilicum), a concentrate from the oregano (Origanum vulgare), a concentrate from the cinnamon tree (Cinnamonum cassia), a concentrate from the carrot (Dacus carota), a concentrate from elderberry (Sambucus nigra), an extract from currant (Ribes), a concentrate from blueberry (Vaccinium), a concentrate from raspberry (Rubus idaeus), a concentrate from blackberry (Rubus spp.) Contains concentrate from the apple berry (Aronia), a concentrate from the spinach (Spinacia oleracea), a concentrate from the cherry (Prunus avium), an extract from the blueberry (Vaccinium) and a concentrate from the Brussels sprouts (Brassica oleracea gemmifera). Te EE LU101728 | 7. Composition according to one of the preceding claims, 100 g of the Composition | - 10 mg to 5000 mg, preferably 50 mg to 4000 mg, the | Pepper component, | - 20 mg to 1000 mg, preferably 80 mg to 400 mg, of curcumin Cyclodextrin blend, | - optionally 1 mg to 1000 mg, preferably 5 mg to 60 mg, of the extract from | the ginger (Zingiber officinale), | - optionally 5 mg to 500 mg, preferably 10 mg to 100 mg, of; Algae component and | - 50 mg to 1000 mg, preferably 100 mg to 500 mg, of the mixture of | Fruits, vegetables and spices / included. 1 8. Composition according to one of the preceding claims, further comprising one or more components selected from: - Vitamin C, preferably 500 mg to 2000 mg per 100 g of composition; / - Niacin, preferably 100 mg to 800 mg per 100 g of composition; Caffeine, preferably 50 mg to 500 mg per 100 g of composition; / - Alpha-tocopheryl acetate, preferably 20 mg to 300 mg per 100 g / composition; | - Pantothensdure, preferably 20 mg to 100 mg per 100 g | Composition; | Pyridoxine, preferably 5 mg to 60 mg per 100 g of composition; | Thiamine, preferably 5 mg to 60 mg per 100 g of composition; Riboflavin, preferably 4 mg to 40 mg per 100 g of composition; - Cyanocobolamine, preferably 4 pg to 20 µg per 100 g of composition; Folic acid, preferably 0.5 mg to 5 mg per 100 g of composition; - Biotin, preferably 0.5 mg to 5 mg per 100 g of composition; Beta-carotene, preferably 4 mg to 30 mg per 100 g of composition; yeast enriched with selenium, preferably 10 mg to 500 mg per 100 g of composition; Gum arabic, preferably 10 g to 30 g per 100 g of composition; - Vegetable fibers, preferably from oats, peas, rice and apple, preferably 10 g to 25 g per 100 g of composition; Pectin and / or guar gum, preferably a total of 1 to 6 g per 100 g of composition; -_— aaa prs) Guarana extract, preferably 1 g to 3 g per 100 g of composition; LU101728 | - Lactic acid cultures (Lactobacillus acidophilus, Lactobacillus reuteri). preferably 0.1 g to 1 g per 100 g of composition; | Inulin, preferably 0.1 g to 1 g per 100 g of composition; | - Grape seed extract, preferably 1 mg to 20 mg per 100 g: composition. | 9. Composition according to one of the preceding claims, further comprising / one or more components selected from: | Citric acid, preferably 1 g to 5 g per 100 g of composition; Ê - fructose, preferably 20 g to 70 g per 100 g of composition; | - Beetroot powder (concentrate of the beetroot juice, maltodextrin and, citric acid), preferably 0.1 g to 2 g per 100 g of composition; | - Multi enzyme complex of amylase, lactase, protease, cellulase, lipase, | preferably 0.1 g to 1 g per 100 g of composition; ; - Steviol glycosides, preferably 0.01 g to 0.5 g per 100 g of composition. | 10. Food supplement containing a composition according to a of the previous claims. | ; 11. Composition as a dietary supplement for children, containing 10 a pepper component, o a curcumin-cyclodextrin mixture and | o a mixture of fruits, vegetables and spices. | 12. Composition as a dietary supplement for children according to claim 11, where 100 g | - 10 mg to 5000 mg, preferably 50 mg to 4000 mg, the | Pepper component, | - 4 mg to 300 mg, preferably 8 mg to 60 mg, of curcumin-cyclodextrin | Mixture and | - 50 mg to 1000 mg, preferably 100 mg to 500 mg, of the mixture of | Fruits, Vegetables and Spices contain. | 13. Composition as a dietary supplement for children according to one of the Claims 11 to 12, further comprising one or more components | selected from:! 25 | - Vitamin C, preferably 500 mg to 2000 mg per 100 g; LU101728 | - Niacin, preferably 50 mg to 600 mg per 100 g; | - Alpha-tocopheryl acetate, preferably 80 mg to 300 mg per 100 g; | Pantothenic acid, preferably 50 mg to 100 mg per 100 g; Pyridoxine, preferably 5 mg to 40 mg per 100 g; | Thiamine, preferably 5 mg to 50 mg per 100 g; | - Riboflavin, preferably 4 mg to 40 mg per 100 g; | Cyanocobolamine, preferably 10 µg to 50 µg per 100 g; | Folic acid, preferably 0.5 mg to 3 mg per 100 g; | - Biotin, preferably 0.2 mg to 1 mg per 100 g; | Beta-carotene, preferably 10 mg to 50 mg per 100 g; | - Chromium picolinate and / or chromium trichloride, in each case preferably from 0.5 mg to 5% mg per 100 g; | Yeast enriched with selenium, preferably 50 to 400 mg per 100 g; Zinc gluconate, preferably 100 mg to 500 mg per 100 g; | Copper (ID) gluconate, preferably 20 mg to 80 mg per 100 g; | Cholecalciferol, preferably 50 Hg to 250 pg per 100 g; | Trimagnesium citrate, preferably 3 to 11 g per 100 g; | Calcium hydrogen phosphate, preferably 0.5 to 3 g per 100 g; | Cacium lactate, preferably 0.2 g to 1.0 g per 100 g; ] - milk mineral concentrate, preferably 3 g to 15 g per 100 g; | - Inulin, preferably 40 g to 80 g per 100 g. | 14. Composition as a dietary supplement for children according to one of the Claims 11 to 13, further comprising one or more components selected from: - citric acid, preferably 3 to 11 g per 100 g; - Steviol glycosides, preferably 0.01 g to 1.0 g per 100 g. 15. A method for producing a composition according to one of claims 1 to 9, a food supplement according to claim 10 or a Composition as a nutritional supplement for children according to one of claims 11 to 14, comprising: - Providing in a vessel and stirring o the pepper component, o the curcumin-cyclodextrin mixture, o optionally the extract from the ginger (Zingiber officinale), - Tega ao optional the algae component and LU101728 | o the mixture of fruits, vegetables and spices; ’ Adding further components and stirring to obtain an intermediate, the addition of at least one component preferably being carried out a) a in portions in portions of a total amount of the component and interrupted by stirring or b) continuously with stirring; ! - Filling the intermediate product in cans, bags or capsules. f |