LU101183B1 - Novel mek-inhibitor for the treatment of viral and bacterial infections - Google Patents
Novel mek-inhibitor for the treatment of viral and bacterial infections Download PDFInfo
- Publication number
- LU101183B1 LU101183B1 LU101183A LU101183A LU101183B1 LU 101183 B1 LU101183 B1 LU 101183B1 LU 101183 A LU101183 A LU 101183A LU 101183 A LU101183 A LU 101183A LU 101183 B1 LU101183 B1 LU 101183B1
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- LU
- Luxembourg
- Prior art keywords
- virus
- infection
- pharmaceutically acceptable
- treatment
- acceptable salt
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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| CN202080044394.4A CN114007598A (zh) | 2019-04-16 | 2020-04-16 | 用于治疗病毒和细菌感染的新型mek抑制剂 |
| EA202192454A EA202192454A1 (ru) | 2019-04-16 | 2020-04-16 | Новый ингибитор mek для лечения вирусных и бактериальных инфекций |
| PCT/EP2020/060692 WO2020212478A1 (en) | 2019-04-16 | 2020-04-16 | Novel mek-inhibitor for the treatment of viral and bacterial infections |
| EP20724748.7A EP3955908B1 (en) | 2019-04-16 | 2020-04-16 | Novel mek-inhibitor for the treatment of viral and bacterial infections |
| ES20724748T ES3012533T3 (en) | 2019-04-16 | 2020-04-16 | Novel mek-inhibitor for the treatment of viral and bacterial infections |
| MX2021012604A MX2021012604A (es) | 2019-04-16 | 2020-04-16 | Nuevo inhibidor de mek para el tratamiento de infecciones virales y bacterianas. |
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| KR1020217036169A KR20210153642A (ko) | 2019-04-16 | 2020-04-16 | 바이러스 및 박테리아 감염 치료를 위한 신규 mek-억제제 |
| AU2020258002A AU2020258002B2 (en) | 2019-04-16 | 2020-04-16 | Novel MEK-inhibitor for the treatment of viral and bacterial infections |
| JP2025083321A JP2025124703A (ja) | 2019-04-16 | 2025-05-19 | ウイルス感染および細菌感染の治療のための新規ｍｅｋ阻害剤 |
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| WO2024042050A1 (en) * | 2022-08-22 | 2024-02-29 | Atriva Therapeutics Gmbh | Use of mek1/2 inhibitors to synergistically potentiate the antiviral effect of direct-acting anti-coronavirus drugs |
| CN119931962B (zh) * | 2025-04-07 | 2025-08-05 | 北京华诺泰生物医药科技有限公司 | 一种人偏肺病毒的培养方法 |
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| WO2001076570A2 (de) | 2000-04-07 | 2001-10-18 | MedInnova Gesellschaft für medizinische Innovationen aus akademischer Forschung mbH | Verwendung von substanzen, die als kaskaden-inhibitor der raf/mek/erk-signalkaskade wirken, zur herstellung eines arzneimittels gegen dna- und rna-viren. |
| WO2014056894A1 (en) | 2012-10-08 | 2014-04-17 | Westfaelische Wilhelms-Universitaet Muenster | Mek inhibitors in the treatment of virus diseases |
| WO2015173788A1 (en) | 2014-05-16 | 2015-11-19 | Westfaelische Wilhelms-Universitaet Muenster | Novel anti-infective strategy against influenza virus and s. aureus coinfections |
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| WO2000040237A1 (en) * | 1999-01-07 | 2000-07-13 | Warner-Lambert Company | Antiviral method using mek inhibitors |
| KR20020012315A (ko) * | 1999-07-16 | 2002-02-15 | 로즈 암스트롱, 크리스틴 에이. 트러트웨인 | Ｍｅｋ 저해제를 사용한 만성 통증의 치료 방법 |
| EP3973960B1 (en) * | 2017-10-17 | 2025-09-03 | Atriva Therapeutics GmbH | Novel mek-inhibitor for the treatment of viral and bacterial infections |
| KR20220074869A (ko) * | 2019-08-27 | 2022-06-03 | 아트리바 테라퓨틱스 게엠베하 | Mek 억제제와 캡-의존성 엔도뉴클레아제 억제제의 조합 |
| JP7802365B2 (ja) * | 2019-10-08 | 2026-01-20 | アトリバ セラピューティクス ゲーエムベーハー | ハンタウイルス感染症の処置のためのｍｅｋ阻害剤 |
| EP3912623B1 (en) * | 2020-05-20 | 2024-07-31 | Atriva Therapeutics GmbH | Pd-0184264 for the treatment of coronavirus infections and/or covid-19 cytokine storm |
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Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
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| WO2001076570A2 (de) | 2000-04-07 | 2001-10-18 | MedInnova Gesellschaft für medizinische Innovationen aus akademischer Forschung mbH | Verwendung von substanzen, die als kaskaden-inhibitor der raf/mek/erk-signalkaskade wirken, zur herstellung eines arzneimittels gegen dna- und rna-viren. |
| WO2014056894A1 (en) | 2012-10-08 | 2014-04-17 | Westfaelische Wilhelms-Universitaet Muenster | Mek inhibitors in the treatment of virus diseases |
| WO2015173788A1 (en) | 2014-05-16 | 2015-11-19 | Westfaelische Wilhelms-Universitaet Muenster | Novel anti-infective strategy against influenza virus and s. aureus coinfections |
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Also Published As
| Publication number | Publication date |
|---|---|
| JP2025124703A (ja) | 2025-08-26 |
| KR20210153642A (ko) | 2021-12-17 |
| EA202192454A1 (ru) | 2022-03-22 |
| JP2022529343A (ja) | 2022-06-21 |
| CA3136171A1 (en) | 2020-10-22 |
| CN114007598A (zh) | 2022-02-01 |
| US20220193017A1 (en) | 2022-06-23 |
| AU2020258002B2 (en) | 2025-12-18 |
| AU2020258002A1 (en) | 2021-11-18 |
| ES3012533T3 (en) | 2025-04-09 |
| BR112021020605A2 (pt) | 2021-12-07 |
| EP3955908A1 (en) | 2022-02-23 |
| MX2021012604A (es) | 2021-11-12 |
| US12350244B2 (en) | 2025-07-08 |
| WO2020212478A1 (en) | 2020-10-22 |
| EP3955908C0 (en) | 2025-01-22 |
| EP3955908B1 (en) | 2025-01-22 |
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