LTIP1632A - New antibody-superantigen conjugates, process for preparing thereof, process for target cell lysis and use of conjugates in pharmaceutical compositions - Google Patents

New antibody-superantigen conjugates, process for preparing thereof, process for target cell lysis and use of conjugates in pharmaceutical compositions

Info

Publication number
LTIP1632A
LTIP1632A LTIP1632A LTIP1632A LTIP1632A LT IP1632 A LTIP1632 A LT IP1632A LT IP1632 A LTIP1632 A LT IP1632A LT IP1632 A LTIP1632 A LT IP1632A LT IP1632 A LTIP1632 A LT IP1632A
Authority
LT
Lithuania
Prior art keywords
conjugates
preparing
pharmaceutical compositions
target cell
cell lysis
Prior art date
Application number
LTIP1632A
Inventor
Terje Kalland
Gunnar Hedlund
Mikael Dohlsten
Peter Lando
Eva Akerblom
Original Assignee
Kabi Pharmacia Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kabi Pharmacia Ab filed Critical Kabi Pharmacia Ab
Publication of LTIP1632A publication Critical patent/LTIP1632A/en
Publication of LT3909B publication Critical patent/LT3909B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
    • C07C217/02—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C217/04—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C217/06—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted
    • C07C217/08—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted the oxygen atom of the etherified hydroxy group being further bound to an acyclic carbon atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
    • C07C217/02—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C217/50—Ethers of hydroxy amines of undetermined structure, e.g. obtained by reactions of epoxides with hydroxy amines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C235/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
    • C07C235/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton
    • C07C235/04—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C235/08—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton being acyclic and saturated having the nitrogen atom of at least one of the carboxamide groups bound to an acyclic carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C07C255/01—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms
    • C07C255/11—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms containing cyano groups and singly-bound oxygen atoms bound to the same saturated acyclic carbon skeleton
    • C07C255/13—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms containing cyano groups and singly-bound oxygen atoms bound to the same saturated acyclic carbon skeleton containing cyano groups and etherified hydroxy groups bound to the carbon skeleton

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
LTIP1632A 1990-07-20 1993-12-20 New antibody-superantigen conjugates, process for preparing thereof, process for target cell lysis and use of conjugates in pharmaceutical compositions LT3909B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE9002484A SE9002484L (en) 1990-07-20 1990-07-20 NEW SUBSTITUTED POLYETERS

Publications (2)

Publication Number Publication Date
LTIP1632A true LTIP1632A (en) 1995-07-25
LT3909B LT3909B (en) 1996-04-25

Family

ID=20380036

Family Applications (1)

Application Number Title Priority Date Filing Date
LTIP1632A LT3909B (en) 1990-07-20 1993-12-20 New antibody-superantigen conjugates, process for preparing thereof, process for target cell lysis and use of conjugates in pharmaceutical compositions

Country Status (2)

Country Link
LT (1) LT3909B (en)
SE (1) SE9002484L (en)

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0180171B1 (en) 1984-10-31 1992-04-08 Massachusetts Institute Of Technology Process for making a targeted cell susceptible to lysis by cytotoxic t lymphocytes
EP0334300A1 (en) 1988-03-21 1989-09-27 Neorx Corporation The use of monoclonal antibodies and conjugates thereof as signals to direct sensitized effector cells to tumor sites
JPH02196799A (en) 1988-04-08 1990-08-03 Agency Of Ind Science & Technol Complex of anti-human cancer protein
DE3825615A1 (en) 1988-07-28 1990-02-01 Behringwerke Ag ANTIGENT CONSTRUCTS OF "MAJOR HISTOCOMPATIBILITY COMPLEX" CLASS I ANTIGENS WITH SPECIFIC CARRIER MOLECULES, THEIR PRODUCTION AND USE
US5185254A (en) 1988-12-29 1993-02-09 The Wistar Institute Gene family of tumor-associated antigens
GB8907310D0 (en) 1989-03-31 1989-05-17 Medical Res Council Heteroconjugates
SE8903100D0 (en) 1989-09-20 1989-09-20 Pharmacia Ab NEW PHARMACEUTICAL AGENT

Also Published As

Publication number Publication date
SE9002484D0 (en) 1990-07-20
LT3909B (en) 1996-04-25
SE9002484L (en) 1992-01-21

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Legal Events

Date Code Title Description
PC9A Transfer of patents

Owner name: ACTIVE BIOTECH AB, SE

Effective date: 20040316

PD9A Change of patent owner

Owner name: PHARMACIA AB, SE

Effective date: 20040316

MM9A Lapsed patents

Effective date: 20071220