LTIP111A - The use of certain therapeutically imidazoles for manufacture of pharmaceutical preparations to be administered transdermally - Google Patents

The use of certain therapeutically imidazoles for manufacture of pharmaceutical preparations to be administered transdermally

Info

Publication number
LTIP111A
LTIP111A LTIP111A LTIP111A LTIP111A LT IP111 A LTIP111 A LT IP111A LT IP111 A LTIP111 A LT IP111A LT IP111 A LTIP111 A LT IP111A LT IP111 A LTIP111 A LT IP111A
Authority
LT
Lithuania
Prior art keywords
pct
imidazoles
manufacture
pharmaceutical preparations
administered transdermally
Prior art date
Application number
LTIP111A
Other languages
Lithuanian (lt)
Inventor
Harry Jalonen
Arvo Sakari Risto Lammintausta
Original Assignee
Orion-Yhtymae Oy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Orion-Yhtymae Oy filed Critical Orion-Yhtymae Oy
Publication of LTIP111A publication Critical patent/LTIP111A/en
Publication of LT3005B publication Critical patent/LT3005B/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7069—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained otherwise than by reactions only involving carbon to carbon unsaturated bonds, e.g. polysiloxane, polyesters, polyurethane, polyethylene oxide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Dermatology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)

Abstract

PCT No. PCT/FI92/00166 Sec. 371 Date Nov. 12, 1993 Sec. 102(e) Date Nov. 12, 1993 PCT Filed May 27, 1992 PCT Pub. No. WO92/21334 PCT Pub. Date Dec. 10, 1992.This invention relates to a transdermal preparation comprising a therapeutically active compound of the formula: <IMAGE> (I) or <IMAGE> (II) where R1, R2, and R3, which can be the same or different are H, CH3, C2H5 or Cl; X is CH=CH or (CH2)n where n is 1 to 3 or X is -C(OR5)H- where R5 is methyl or ethyl; and R4 is hydrogen or a straight alkyl of 1 to 4 carbon atoms. The transdermal administration of the compounds can be accomplished by preparations in the form of ointments, emulsions, lotions, solutions, creams or transdermal patches.
LTIP111A 1991-05-31 1992-05-29 The use of certain therapeutically imidazoles for manufacture of pharmaceutical preparations to be administered transdermally. LT3005B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB9111773A GB2256135B (en) 1991-05-31 1991-05-31 Transdermal administration of 4-substituted imidazoles

Publications (2)

Publication Number Publication Date
LTIP111A true LTIP111A (en) 1994-03-25
LT3005B LT3005B (en) 1994-08-25

Family

ID=10695905

Family Applications (1)

Application Number Title Priority Date Filing Date
LTIP111A LT3005B (en) 1991-05-31 1992-05-29 The use of certain therapeutically imidazoles for manufacture of pharmaceutical preparations to be administered transdermally.

Country Status (18)

Country Link
US (1) US5464628A (en)
EP (1) EP0586467B1 (en)
JP (1) JP3269822B2 (en)
AT (1) ATE199317T1 (en)
AU (1) AU1780892A (en)
CA (1) CA2110162C (en)
DE (1) DE69231709T2 (en)
DK (1) DK0586467T3 (en)
EE (1) EE02994B1 (en)
ES (1) ES2154636T3 (en)
FI (1) FI935350A (en)
GB (1) GB2256135B (en)
GR (1) GR3035499T3 (en)
IE (1) IE66188B1 (en)
LT (1) LT3005B (en)
LV (1) LV10042B (en)
NO (1) NO307365B1 (en)
WO (1) WO1992021334A1 (en)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997006788A1 (en) * 1995-08-14 1997-02-27 Janssen Pharmaceutica N.V. Transdermal administration of vorozole
US5891461A (en) * 1995-09-14 1999-04-06 Cygnus, Inc. Transdermal administration of olanzapine
US5807570A (en) * 1995-09-29 1998-09-15 Cygnus, Inc. Transdermal administration of ropinirole and analogs thereof
GB9614098D0 (en) 1996-07-05 1996-09-04 Orion Yhtymae Oy Transdermal delivery of levosimendan
DE19820151A1 (en) * 1998-05-06 1999-11-11 Hexal Ag Transdermal therapeutic system for the application of candesartan
TW200930291A (en) 2002-04-29 2009-07-16 Bayer Cropscience Ag Pesticidal heterocycles
FI20041425A0 (en) * 2004-11-05 2004-11-05 Orion Corp Transmucosal veterinary composition
ES2536478T3 (en) * 2004-12-15 2015-05-25 Teikoku Seiyaku Co., Ltd. External patches containing ethofenamate
ES2338716T3 (en) 2006-01-27 2010-05-11 F.Hoffmann-La Roche Ag USE OF 4-IMIDAZOL DERIVATIVES FOR CNS DISORDERS.
CA2659379A1 (en) * 2006-08-08 2008-02-14 Intervet International B.V. Composition for enhanced antiparasitic activity
US7795263B2 (en) * 2008-07-08 2010-09-14 Wildlife Laboratories, Inc. Pharmaceutical combination for and method of anesthetizing and immobilizing non-domesticated mammals
US20210323929A1 (en) * 2018-07-18 2021-10-21 Clexio Biosciences Ltd. Purified Detomidine, Process of Preparing and Methods of Use
WO2020222188A1 (en) 2019-05-01 2020-11-05 Clexio Biosciences Ltd. Methods of treating pruritus
CN112220767B (en) * 2020-09-25 2022-10-25 安徽省公众检验研究院有限公司 Preparation method of altimezole hydrochloride sustained-release tablet

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU518569B2 (en) * 1979-08-07 1981-10-08 Farmos-Yhtyma Oy 4-benzyl- and 4-benzoyl imidazole derivatives
GB2069481B (en) * 1980-02-13 1983-07-27 Farmos Oy Substituted imidazole derivatives
GB2101114B (en) * 1981-07-10 1985-05-22 Farmos Group Ltd Substituted imidazole derivatives and their preparation and use
GB2167408B (en) 1984-11-23 1988-05-25 Farmos Oy Substituted imidazole derivatives and their preparation and use
US4672344A (en) 1985-04-19 1987-06-09 Siemens Aktiengesellschaft Polarized electromagnetic relay
FI864570A0 (en) 1986-11-11 1986-11-11 Farmos Oy THERAPEUTIC ANVAENDBAR FOERENING.
US5124157A (en) * 1989-08-18 1992-06-23 Cygnus Therapeutic Systems Method and device for administering dexmedetomidine transdermally
FI894911A0 (en) * 1989-10-17 1989-10-17 Farmos Oy EN TERAPEUTISKT VAERDEFULL FOERENING.
US5304569A (en) * 1989-11-13 1994-04-19 Orion-Yhtyma Oy Compositions and their use in lowering intraocular pressure

Also Published As

Publication number Publication date
GB9111773D0 (en) 1991-07-24
NO307365B1 (en) 2000-03-27
JPH06507618A (en) 1994-09-01
FI935350A0 (en) 1993-11-30
DE69231709T2 (en) 2001-10-04
ATE199317T1 (en) 2001-03-15
US5464628A (en) 1995-11-07
NO934261D0 (en) 1993-11-25
IE66188B1 (en) 1995-12-13
EP0586467B1 (en) 2001-02-28
ES2154636T3 (en) 2001-04-16
FI935350A (en) 1993-11-30
CA2110162A1 (en) 1992-12-10
EP0586467A1 (en) 1994-03-16
CA2110162C (en) 2002-11-12
IE921938A1 (en) 1992-12-02
NO934261L (en) 1993-11-25
WO1992021334A1 (en) 1992-12-10
GB2256135B (en) 1995-01-18
LT3005B (en) 1994-08-25
LV10042B (en) 1995-02-20
JP3269822B2 (en) 2002-04-02
LV10042A (en) 1994-05-10
AU1780892A (en) 1993-01-08
GB2256135A (en) 1992-12-02
DK0586467T3 (en) 2001-03-26
DE69231709D1 (en) 2001-04-05
GR3035499T3 (en) 2001-06-29
EE02994B1 (en) 1997-06-16

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Legal Events

Date Code Title Description
MM9A Lapsed patents

Effective date: 20060529