LT3589638T - Junginiai, naudingi ror-gama-t slopinimui - Google Patents

Junginiai, naudingi ror-gama-t slopinimui

Info

Publication number
LT3589638T
LT3589638T LTEP18710653.9T LT18710653T LT3589638T LT 3589638 T LT3589638 T LT 3589638T LT 18710653 T LT18710653 T LT 18710653T LT 3589638 T LT3589638 T LT 3589638T
Authority
LT
Lithuania
Prior art keywords
gamma
compounds useful
inhibiting ror
ror
inhibiting
Prior art date
Application number
LTEP18710653.9T
Other languages
English (en)
Inventor
Christian Alexander Clarke
Charles Willis Lugar Iii
John Richard Morphy
Timothy Ivo Richardson
Helene Rudyk
Selma Sapmaz
Ryan Edward Stites
Grant Mathews Vaught
Original Assignee
Eli Lilly And Company
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eli Lilly And Company filed Critical Eli Lilly And Company
Publication of LT3589638T publication Critical patent/LT3589638T/lt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D495/00Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/12Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
    • C07D495/20Spiro-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
LTEP18710653.9T 2017-03-02 2018-02-27 Junginiai, naudingi ror-gama-t slopinimui LT3589638T (lt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201762466117P 2017-03-02 2017-03-02
PCT/US2018/019920 WO2018160550A1 (en) 2017-03-02 2018-02-27 Compounds useful for inhibiting ror-gamma-t

Publications (1)

Publication Number Publication Date
LT3589638T true LT3589638T (lt) 2021-06-10

Family

ID=61622740

Family Applications (1)

Application Number Title Priority Date Filing Date
LTEP18710653.9T LT3589638T (lt) 2017-03-02 2018-02-27 Junginiai, naudingi ror-gama-t slopinimui

Country Status (15)

Country Link
US (1) US11008336B2 (lt)
EP (1) EP3589638B1 (lt)
JP (1) JP6766273B2 (lt)
CN (1) CN110337440B (lt)
CY (1) CY1124177T1 (lt)
DK (1) DK3589638T3 (lt)
ES (1) ES2871911T3 (lt)
HR (1) HRP20210898T1 (lt)
HU (1) HUE054483T2 (lt)
LT (1) LT3589638T (lt)
PL (1) PL3589638T3 (lt)
PT (1) PT3589638T (lt)
RS (1) RS61788B1 (lt)
SI (1) SI3589638T1 (lt)
WO (1) WO2018160550A1 (lt)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2022122740A1 (en) 2020-12-07 2022-06-16 Diaccurate Ror-gamma inhibitors for the treatment of ror-gamma-dependent cancer

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2492379A1 (en) * 2002-07-17 2004-01-22 Warner-Lambert Company Llc Combination of an allosteric inhibitor of matrix metalloproteinase-13 with celecoxib or valdecoxib
UA107943C2 (en) 2009-11-16 2015-03-10 Lilly Co Eli Compounds of spiropiperidines as antagonists of the orl-1 receptors
ES2436241T3 (es) 2009-11-16 2013-12-27 Eli Lilly And Company Compuestos de espiropiperidina como antagonistas de receptor oral-1
TWI582096B (zh) 2011-12-06 2017-05-11 美國禮來大藥廠 用於酒精依賴及濫用處理之4',5'-二氫螺[哌啶-4,7'-噻吩并[2,3-c]哌喃]化合物
US9868748B2 (en) 2013-05-01 2018-01-16 Vitae Pharmaceuticals, Inc. Thiazolopyrrolidine inhibitors of ROR- γ
WO2015017335A1 (en) 2013-07-30 2015-02-05 Boehringer Ingelheim International Gmbh Azaindole compounds as modulators of rorc
WO2015101928A1 (en) * 2013-12-31 2015-07-09 Aurigene Discovery Technologies Limited Fused thiophene and thiazole derivatives as ror gamma modulators
WO2015112754A1 (en) * 2014-01-24 2015-07-30 Abbvie Inc. Furo-3-carboxamide derivatives and methods of use
JO3638B1 (ar) 2015-09-09 2020-08-27 Lilly Co Eli مركبات مفيدة في تثبيط ror - جاما- t
DK3589637T3 (da) * 2017-03-02 2021-06-14 Lilly Co Eli Forbindelser, der er anvendelige til inhibering af ROR-GAMMA-T

Also Published As

Publication number Publication date
EP3589638A1 (en) 2020-01-08
CN110337440B (zh) 2021-08-03
SI3589638T1 (sl) 2021-08-31
HUE054483T2 (hu) 2021-09-28
WO2018160550A1 (en) 2018-09-07
PT3589638T (pt) 2021-05-27
US11008336B2 (en) 2021-05-18
DK3589638T3 (da) 2021-06-07
CN110337440A (zh) 2019-10-15
JP6766273B2 (ja) 2020-10-07
RS61788B1 (sr) 2021-06-30
ES2871911T3 (es) 2021-11-02
HRP20210898T1 (hr) 2021-08-20
US20200048279A1 (en) 2020-02-13
EP3589638B1 (en) 2021-04-07
CY1124177T1 (el) 2022-05-27
JP2020509049A (ja) 2020-03-26
PL3589638T3 (pl) 2021-09-27

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