LT3140287T - Nauja ivabradino druska ir jos gamybos būdas - Google Patents

Nauja ivabradino druska ir jos gamybos būdas

Info

Publication number
LT3140287T
LT3140287T LTEP15725827.8T LT15725827T LT3140287T LT 3140287 T LT3140287 T LT 3140287T LT 15725827 T LT15725827 T LT 15725827T LT 3140287 T LT3140287 T LT 3140287T
Authority
LT
Lithuania
Prior art keywords
new
preparation process
ivabradine
salt
ivabradine salt
Prior art date
Application number
LTEP15725827.8T
Other languages
English (en)
Lithuanian (lt)
Inventor
Michael Lynch
Patrick COINTEPAS
David LAFARGUE
Gilles Briault
Original Assignee
Les Laboratoires Servier
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Les Laboratoires Servier filed Critical Les Laboratoires Servier
Publication of LT3140287T publication Critical patent/LT3140287T/lt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D223/16—Benzazepines; Hydrogenated benzazepines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C65/00—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C65/01—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing hydroxy or O-metal groups
    • C07C65/105—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing hydroxy or O-metal groups polycyclic
    • C07C65/11—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing hydroxy or O-metal groups polycyclic with carboxyl groups on a condensed ring system containing two rings

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Saccharide Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
LTEP15725827.8T 2014-05-06 2015-05-06 Nauja ivabradino druska ir jos gamybos būdas LT3140287T (lt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR1454081A FR3020810B1 (fr) 2014-05-06 2014-05-06 Nouveau sel de l'ivabradine et son procede de preparation.
PCT/FR2015/051201 WO2015170053A1 (fr) 2014-05-06 2015-05-06 Nouveau sel de l'ivabradine et son procédé de préparation

Publications (1)

Publication Number Publication Date
LT3140287T true LT3140287T (lt) 2018-04-10

Family

ID=51518916

Family Applications (1)

Application Number Title Priority Date Filing Date
LTEP15725827.8T LT3140287T (lt) 2014-05-06 2015-05-06 Nauja ivabradino druska ir jos gamybos būdas

Country Status (21)

Country Link
US (1) US9856221B2 (zh)
EP (1) EP3140287B1 (zh)
JP (1) JP2017514848A (zh)
CN (1) CN106458915B (zh)
AU (1) AU2015257518B2 (zh)
CA (1) CA2947475C (zh)
CY (1) CY1120402T1 (zh)
DK (1) DK3140287T3 (zh)
ES (1) ES2672927T3 (zh)
FR (1) FR3020810B1 (zh)
HR (1) HRP20180716T1 (zh)
HU (1) HUE037755T2 (zh)
LT (1) LT3140287T (zh)
MA (1) MA39756B1 (zh)
ME (1) ME03062B (zh)
NO (1) NO3140287T3 (zh)
PL (1) PL3140287T3 (zh)
PT (1) PT3140287T (zh)
RS (1) RS57147B1 (zh)
SI (1) SI3140287T1 (zh)
WO (1) WO2015170053A1 (zh)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR110768A1 (es) * 2017-01-31 2019-05-02 Gilead Sciences Inc Formas cristalinas de tenofovir alafenamida

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI832053L (fi) * 1982-06-10 1983-12-11 Syntex Inc Nonapeptid- och dekapeptidanaloger av lhrh anvaendbara som lhrh-antagonister samt deras framstaellningsfoerfarande
FR2681862B1 (fr) 1991-09-27 1993-11-12 Adir Cie Nouvelles (benzocycloalkyl)alkylamines, leur procede de preparation, et les compositions pharmaceutiques qui les contiennent.
KR101488403B1 (ko) * 2005-05-18 2015-02-04 엠펙스 파마슈티컬즈, 인코포레이티드 에어로졸화된 플루오로퀴놀론 및 이의 용도
WO2007064845A1 (en) * 2005-11-29 2007-06-07 Pr Pharmaceuticals, Inc. Sustained release butorphanol drug delivery compositions for analgesia
US8653106B2 (en) * 2010-07-30 2014-02-18 Pisgah Laboratories, Inc. Abuse deterrent and anti-dose dumping pharmaceutical salts useful for the treatment of attention deficit/hyperactivity disorder
US20080293695A1 (en) * 2007-05-22 2008-11-27 David William Bristol Salts of physiologically active and psychoactive alkaloids and amines simultaneously exhibiting bioavailability and abuse resistance
FR2920773B1 (fr) * 2007-09-11 2009-10-23 Servier Lab Derives de 1,2,4,5-tetrahydro-3h-benzazepines, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
EP2453870A2 (en) * 2009-06-24 2012-05-23 MSD Oss B.V. Injectable formulations containing asenapine and method of treatment using same
WO2011104723A2 (en) * 2010-02-23 2011-09-01 Ind-Swift Laboratories Limited Acid addition salts of ivabradine and preparation thereof
EP2946772A1 (en) * 2010-06-14 2015-11-25 ratiopharm GmbH Solid ivabradine-containing composition
FR2961105B1 (fr) * 2010-06-15 2013-02-08 Servier Lab Utilisation de l'association d'un inhibiteur du courant if sinusal et d'un inhibiteur de l'enzyme de conversion de l'angiotensine pour le traitement de l'insuffisance cardiaque
EP2702060B1 (en) * 2011-04-26 2015-12-30 Torrent Pharmaceuticals Limited Acid addition salts of risperidone and pharmaceutical compositions thereof
CN102908327B (zh) * 2011-08-05 2015-03-11 江苏恒瑞医药股份有限公司 伊伐布雷定或其可药用盐的缓释制剂
US9079974B2 (en) * 2011-12-21 2015-07-14 The University Of Miami GH-RH analogs with potent agonistic effects

Also Published As

Publication number Publication date
FR3020810B1 (fr) 2016-05-06
DK3140287T3 (en) 2018-06-14
PL3140287T3 (pl) 2018-07-31
EP3140287B1 (fr) 2018-03-07
AU2015257518B2 (en) 2018-12-13
CY1120402T1 (el) 2019-07-10
HUE037755T2 (hu) 2018-09-28
CN106458915A (zh) 2017-02-22
NO3140287T3 (zh) 2018-08-04
HRP20180716T1 (hr) 2018-06-15
US9856221B2 (en) 2018-01-02
CA2947475C (fr) 2018-07-10
MA39756B1 (fr) 2018-05-31
JP2017514848A (ja) 2017-06-08
WO2015170053A1 (fr) 2015-11-12
RS57147B1 (sr) 2018-07-31
EP3140287A1 (fr) 2017-03-15
US20170050932A1 (en) 2017-02-23
SI3140287T1 (en) 2018-05-31
ES2672927T3 (es) 2018-06-18
CA2947475A1 (fr) 2015-11-12
AU2015257518A1 (en) 2016-11-03
FR3020810A1 (fr) 2015-11-13
PT3140287T (pt) 2018-03-22
MA39756A (fr) 2018-03-07
ME03062B (me) 2019-01-20
CN106458915B (zh) 2019-05-07

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