LT2854768T - Pemetreksedo farmacinės kompozicijos - Google Patents

Pemetreksedo farmacinės kompozicijos

Info

Publication number
LT2854768T
LT2854768T LTEP13730070.3T LT13730070T LT2854768T LT 2854768 T LT2854768 T LT 2854768T LT 13730070 T LT13730070 T LT 13730070T LT 2854768 T LT2854768 T LT 2854768T
Authority
LT
Lithuania
Prior art keywords
pemetrexed
pharmaceutical compositions
pharmaceutical
compositions
Prior art date
Application number
LTEP13730070.3T
Other languages
English (en)
Inventor
Dhiraj Khattar
Rajesh Khanna
Mukti YADAV
Krishanu BURMAN
Original Assignee
Fresenius Kabi Oncology Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=48656253&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=LT2854768(T) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Fresenius Kabi Oncology Limited filed Critical Fresenius Kabi Oncology Limited
Publication of LT2854768T publication Critical patent/LT2854768T/lt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02Inorganic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/08Solutions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Dermatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Inorganic Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
LTEP13730070.3T 2012-05-30 2013-05-30 Pemetreksedo farmacinės kompozicijos LT2854768T (lt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN1648DE2012 2012-05-30
PCT/IB2013/054456 WO2013179248A1 (en) 2012-05-30 2013-05-30 Pharmaceutical compositions of pemetrexed

Publications (1)

Publication Number Publication Date
LT2854768T true LT2854768T (lt) 2017-06-12

Family

ID=48656253

Family Applications (1)

Application Number Title Priority Date Filing Date
LTEP13730070.3T LT2854768T (lt) 2012-05-30 2013-05-30 Pemetreksedo farmacinės kompozicijos

Country Status (8)

Country Link
US (2) US9421207B2 (lt)
EP (2) EP2854768B1 (lt)
DK (1) DK2854768T3 (lt)
ES (1) ES2624442T3 (lt)
LT (1) LT2854768T (lt)
PT (1) PT2854768T (lt)
SI (1) SI2854768T1 (lt)
WO (1) WO2013179248A1 (lt)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20160051679A1 (en) * 2013-04-12 2016-02-25 Actavis Group Ptc Ehf. Pemetrexed Formulation
KR101485243B1 (ko) 2013-05-08 2015-01-21 씨제이헬스케어 주식회사 안정화된 페메트렉시드 제제
JP6182262B2 (ja) * 2013-06-14 2017-08-16 シントン・ベスローテン・フェンノートシャップ 抗がん剤を含む安定な水溶性医薬組成物
US9688682B2 (en) * 2013-07-16 2017-06-27 Dr. Reddy's Laboratories Limited Crystalline forms of pemetrexed tromethamine salts
CN105611932B (zh) 2013-10-03 2019-02-12 富士胶片株式会社 注射液制剂及其制造方法
JP6120766B2 (ja) * 2013-12-27 2017-04-26 富士フイルム株式会社 注射液製剤及びその製造方法
ES2686870T3 (es) * 2014-03-28 2018-10-22 Fujifilm Corporation Preparación de inyección y método para producirla
GB201418555D0 (en) * 2014-10-16 2014-12-03 Teva Gmbh Pemetrexed formulations
RS60183B1 (sr) * 2014-10-16 2020-06-30 Synthon Bv Tečna farmaceutska kompozicija koja sadrži pemetreksed
DK3256133T3 (da) * 2015-02-13 2022-10-24 Sun Pharmaceutical Ind Ltd Intravenøs infusionsdoseringsform
KR101919436B1 (ko) * 2015-05-28 2018-11-16 주식회사 삼양바이오팜 안정화된 약학 조성물 및 그의 제조방법
GB201511246D0 (en) * 2015-06-25 2015-08-12 Actavis Group Ptc Ehf Pharmaceutical formulation
KR101693675B1 (ko) * 2015-12-14 2017-01-06 주식회사 종근당 페메트렉시드 또는 그의 약제학적으로 허용가능한 염을 함유하는 안정화된 약학조성물
US20170239250A1 (en) * 2016-02-19 2017-08-24 Eagle Pharmaceuticals, Inc. Pemetrexed formulations
KR20240049356A (ko) * 2016-02-19 2024-04-16 이글 파마슈티컬즈 인코포레이티드 페메트렉시드 제제
EP3675819A1 (en) * 2017-08-29 2020-07-08 Fresenius Kabi Oncology Limited Stable liquid compositions of pemetrexed
ES2959975T3 (es) 2017-10-10 2024-02-29 Sun Pharmaceutical Ind Ltd Forma de dosificación para infusión intravenosa de pemetrexed
CN108158989B (zh) * 2018-03-01 2020-08-28 河北爱尔海泰制药有限公司 一种盐酸氨溴索注射液组合物
US10966982B2 (en) * 2018-11-20 2021-04-06 Cipla Limited Stable pharmaceutical formulations of pemetrexed
EP3962453A4 (en) * 2019-05-01 2023-01-25 Intas Pharmaceuticals Ltd. STABLE, READY-TO-USE AQUEOUS PHARMACEUTICAL COMPOSITION OF PEMETREXED
JPWO2021192472A1 (lt) * 2020-03-24 2021-09-30
JP7282065B2 (ja) * 2020-10-05 2023-05-26 イーグル ファーマシューティカルズ, インコーポレイテッド ペメトレキセド製剤

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4977181A (en) 1987-12-18 1990-12-11 Ciba-Geigy Corporation Tromethamine salt of 1-methyl-beta-oxo-alpha-(phenylcarbamoyl)-2-pyrrolepropionitrile
KR0162654B1 (ko) 1989-12-11 1998-11-16 알렌 제이. 시니스갤리 N-(피롤로[2,3-d]피리미딘-3-일아크릴)-글루타민산 유도체
IL96531A (en) 1989-12-11 1995-08-31 Univ Princeton History of Acid N- (Diomeric-H1-Pyrolo] D-2,3 [Pyrimidine-3-Ilacyl (-glutamic, preparation and pharmaceutical preparations containing them)
US6686365B2 (en) 2000-02-04 2004-02-03 Eli Lilly And Company Pharmaceutical composition
DE60127970T2 (de) 2000-06-30 2007-12-20 Eli Lilly And Co., Indianapolis Zusammensetzung, welche ein antifolate und ein methylmalonsäuresenkendes mittel enthält
CN100364993C (zh) 2003-05-30 2008-01-30 江苏恒瑞医药股份有限公司 培美曲噻盐及其制备方法
US7772273B2 (en) 2006-02-10 2010-08-10 Lifecycle Pharma A/S Stabilized atorvastatin
CN101081301A (zh) 2006-05-29 2007-12-05 海南天源康泽医药科技有限公司 含有培美曲塞的药物组合物
US8629152B2 (en) 2006-08-14 2014-01-14 Sicor, Inc. Processes for the preparation of lyophilized pharmaceutically acceptable salts of pemetrexed diacid
WO2010030598A2 (en) * 2008-09-11 2010-03-18 Dr. Reddy's Laboratories Limited Pharmaceutical formulations comprising pemetrexed
IT1401207B1 (it) 2010-06-30 2013-07-12 Magic Production Group S A Dispositivo e procedimento per la chiusura di contenitori
US9655898B2 (en) * 2010-07-28 2017-05-23 Eagle Pharmaceuticals, Inc. Pharmaceutical compositions containing pemetrexed having extended storage stability
US20160051679A1 (en) 2013-04-12 2016-02-25 Actavis Group Ptc Ehf. Pemetrexed Formulation

Also Published As

Publication number Publication date
US9968608B2 (en) 2018-05-15
PT2854768T (pt) 2017-05-19
EP2854768B1 (en) 2017-03-22
EP3210629A1 (en) 2017-08-30
ES2624442T3 (es) 2017-07-14
WO2013179248A1 (en) 2013-12-05
US9421207B2 (en) 2016-08-23
US20160310495A1 (en) 2016-10-27
EP2854768A1 (en) 2015-04-08
SI2854768T1 (sl) 2017-08-31
DK2854768T3 (en) 2017-06-12
US20150111905A1 (en) 2015-04-23

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