KR970042502A - New amine ring compounds - Google Patents

New amine ring compounds Download PDF

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Publication number
KR970042502A
KR970042502A KR1019950056837A KR19950056837A KR970042502A KR 970042502 A KR970042502 A KR 970042502A KR 1019950056837 A KR1019950056837 A KR 1019950056837A KR 19950056837 A KR19950056837 A KR 19950056837A KR 970042502 A KR970042502 A KR 970042502A
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KR
South Korea
Prior art keywords
amine ring
present
general formula
new
ring compound
Prior art date
Application number
KR1019950056837A
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Korean (ko)
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KR100209299B1 (en
Inventor
조성민
박상후
Original Assignee
이웅열
주식회사 코오롱
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Priority to KR1019950056837A priority Critical patent/KR100209299B1/en
Publication of KR970042502A publication Critical patent/KR970042502A/en
Application granted granted Critical
Publication of KR100209299B1 publication Critical patent/KR100209299B1/en

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/10Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/14Nitrogen atoms not forming part of a nitro radical
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/56Nitrogen atoms

Abstract

본 발명은 다음 일반식 (Ⅰ)로 표시되며 3번 위치의 비대칭탄소로 생성되는 광학 이성질체를 포함하는 아민고리 화합물 및 그 산부가염을 제공한다.The present invention provides an amine ring compound and an acid addition salt thereof, which are represented by the following general formula (I) and contain an optical isomer produced by asymmetric carbon at position 3.

상기식중에서 X는 할로겐 원자, -OR1, 또는 -SR2이고(여기서 R1, R2는 서로 같거나 다르며 각각 수소원자 또는 탄소수 1-3개의 저급알킬리를 나타낸다.), n은 1 또는 2의 정수이다.Wherein X is a halogen atom, -OR 1 , or -SR 2 (wherein R 1 , R 2 are the same as or different from each other and each represents a hydrogen atom or lower alkylli having 1-3 carbon atoms), and n is 1 or Is an integer of 2.

본 발명에 따른 상기 일반식 (Ⅰ)의 새로운 아민고리 화합물은 항균활성을 갖는 각종 퀴놀론 유도체 화합물 제조시 도입기로 이용되는 원료화합물인 중간체로서 매우 유용하며 이러한 본 발명의 새로운 화합물을 모핵에 도입한 퀴놀론 항균제는 뛰어난 항균활성을 나타낸다.The new amine ring compound of the general formula (I) according to the present invention is very useful as an intermediate which is a raw material used as an introduction material in the preparation of various quinolone derivative compounds having antibacterial activity, and the quinolone having introduced the new compound of the present invention into the mother nucleus. Antimicrobial agents show excellent antimicrobial activity.

Description

새로운 아민고리 화합물New amine ring compounds

본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음Since this is an open matter, no full text was included.

Claims (1)

다음 일반식(Ⅰ)로 표시되며 3번 위치의 비대칭탄소로 생성되는 광학 이성질체를 포함하는 아민고리 화합물 및 그 산부가염.An amine ring compound and an acid addition salt thereof, which are represented by the following general formula (I) and contain an optical isomer produced by asymmetric carbon at position 3. 상기 식중에서 X는 할로겐 원자, -OR1, 또는 -SR2이고(여기서 R1, R2는 서로 같거나 다르며 각각 수소원자 또는 탄소수 1-3개의 저급알킬기를 나타낸다.), n은 1 또는 2의 정수이다.Wherein X is a halogen atom, -OR 1 , or -SR 2 (wherein R 1 , R 2 are the same as or different from each other and each represents a hydrogen atom or a lower alkyl group of 1 to 3 carbon atoms), and n is 1 or 2 Is an integer.
KR1019950056837A 1995-12-26 1995-12-26 Novel aminocyclic compounds KR100209299B1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
KR1019950056837A KR100209299B1 (en) 1995-12-26 1995-12-26 Novel aminocyclic compounds

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
KR1019950056837A KR100209299B1 (en) 1995-12-26 1995-12-26 Novel aminocyclic compounds

Publications (2)

Publication Number Publication Date
KR970042502A true KR970042502A (en) 1997-07-24
KR100209299B1 KR100209299B1 (en) 1999-07-15

Family

ID=19444534

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019950056837A KR100209299B1 (en) 1995-12-26 1995-12-26 Novel aminocyclic compounds

Country Status (1)

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KR (1) KR100209299B1 (en)

Also Published As

Publication number Publication date
KR100209299B1 (en) 1999-07-15

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