KR970042501A - New amine ring compounds - Google Patents

New amine ring compounds Download PDF

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Publication number
KR970042501A
KR970042501A KR1019950056836A KR19950056836A KR970042501A KR 970042501 A KR970042501 A KR 970042501A KR 1019950056836 A KR1019950056836 A KR 1019950056836A KR 19950056836 A KR19950056836 A KR 19950056836A KR 970042501 A KR970042501 A KR 970042501A
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KR
South Korea
Prior art keywords
amine ring
general formula
ring compound
new amine
antibacterial activity
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Application number
KR1019950056836A
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Korean (ko)
Other versions
KR100209298B1 (en
Inventor
조성민
박상후
Original Assignee
이웅열
주식회사 코오롱
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Publication date
Application filed by 이웅열, 주식회사 코오롱 filed Critical 이웅열
Priority to KR1019950056836A priority Critical patent/KR100209298B1/en
Publication of KR970042501A publication Critical patent/KR970042501A/en
Application granted granted Critical
Publication of KR100209298B1 publication Critical patent/KR100209298B1/en

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/10Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/12Oxygen or sulfur atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/40Oxygen atoms
    • C07D211/42Oxygen atoms attached in position 3 or 5

Abstract

본 발명은 다음 일반식 (Ⅰ)로 표시되며 3번위치의 비대칭탄소로 생성되는 광학 이성질체를 포함하는 새로운 아민고리 화합물 및 그 산 부가염에 관한 것이다.The present invention relates to a novel amine ring compound and an acid addition salt thereof, which are represented by the following general formula (I) and contain an optical isomer produced by the asymmetric carbon at position 3.

상기식에서, R1, R2는 서로 같거나 다르며 각각 수소원자 또는 탄소수 1-3개의 저급알킬기를 나타내고 n은 1 또는 2의 정수이다.Wherein R 1 and R 2 are the same as or different from each other, and each represents a hydrogen atom or a lower alkyl group having 1 to 3 carbon atoms, and n is an integer of 1 or 2.

본 발명에 따른 상기 일반식 (Ⅰ)의 아민고리 화합물은 항균 활성을 갖는 각종 퀴놀론 유도체 화합물 제조시 도입기로 이용되는 원료 중간체로서 매우 유용하며 이 새로운 중간체를 도입한 퀴놀론 항균 화합물은 매우 뛰어난 항균 활성을 갖는다.The amine ring compound of the general formula (I) according to the present invention is very useful as a raw material intermediate used as an introduction material in the preparation of various quinolone derivative compounds having antibacterial activity, and the quinolone antibacterial compound introduced with this new intermediate has excellent antibacterial activity. Have

Description

새로운 아민고리 화합물New amine ring compounds

본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음Since this is an open matter, no full text was included.

Claims (1)

다음 일반식 (Ⅰ)로 표시되며 3번위치의 비대칭탄소로 생성되는 광학 이성질체를 포함하는 새로운 아민고리 화합물 및 그 산부가염.The new amine ring compound and its acid addition salt which are represented by following General formula (I) and contain the optical isomer produced by the asymmetric carbon of 3rd position. 상기식에서 R1, R2는 서로 같거나 다르며 각각 수소원자 또는 탄소수 1-3개의 저급알킬기를 나타내고 n은 1 또는 2 의 정수이다.Wherein R 1 and R 2 are the same as or different from each other, and each represents a hydrogen atom or a lower alkyl group having 1 to 3 carbon atoms, and n is an integer of 1 or 2.
KR1019950056836A 1995-12-26 1995-12-26 Novel amino-cyclic compound KR100209298B1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
KR1019950056836A KR100209298B1 (en) 1995-12-26 1995-12-26 Novel amino-cyclic compound

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
KR1019950056836A KR100209298B1 (en) 1995-12-26 1995-12-26 Novel amino-cyclic compound

Publications (2)

Publication Number Publication Date
KR970042501A true KR970042501A (en) 1997-07-24
KR100209298B1 KR100209298B1 (en) 1999-07-15

Family

ID=19444533

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019950056836A KR100209298B1 (en) 1995-12-26 1995-12-26 Novel amino-cyclic compound

Country Status (1)

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KR (1) KR100209298B1 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR19980015377A (en) * 1996-08-21 1998-05-25 이웅열 New quinolone carboxylic acid compounds and methods for their preparation

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Publication number Publication date
KR100209298B1 (en) 1999-07-15

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