KR970008154B1 - Oral cavity composition - Google Patents

Abstract

The deodorizing agent is manufactured by extracting a leaf of a persimmon tree as an effective component with methanol or ethanol and water at 20-95 deg.C for 4-24 hr . For an example, 100g of the leaf of the persimmon tree, 500g of methanol(99.9%) and 500g of purified water are distilled at 20-95 deg.C for 4-24 hr, cooled at 30 deg.C, extracted, and filtered with a sieve of 400 mesh. 950g of Filtrate is condensed under vacuum at 40 deg.C to give a 21g of concentrated solution of the leaf of the persimmon tree. The extract solution of the leaf of the persimmon tree is used as a liquid type, a spray type, a powder type, a tablet type, and a granule type, the effective concentration of the deodorizing agent is 0.25-5 wt.% as a liquid.

Description

Deodorant Using Persimmon Leaf Extract

The present invention relates to a deodorant using a persimmon leaf extract, and more particularly, to extract the extract solvent to persimmon leaves to extract juice, filtration, concentrated to obtain an extract having a strong deodorizing effect therefrom, and to use it as a deodorant to remove odors will be.

Persimmon tree (Dyospyros Kaki, Thunb) is wild throughout Korea, persimmon leaves contain flavonoid glycosides, tannins, phenols, resins, carcumin compounds, reducing sugars, polysaccharides, essential oils, organic acids, chlorophyll, flavonoid glycosides include astragarine, myristic It contains lean, especially rich in vitamin C. Some persimmon leaves in April and June contain about 100mg in 100g.

Persimmon leaves are said to be good for bronchial protection according to our traditional folk remedies, and because they contain a lot of vitamin C, they help to absorb minerals such as iron, which can easily be lost after drinking too much.

In recent years, odorous substances are rapidly increasing due to the large amount of pollutants released due to industrial advancement, and in particular, interest in bad breath, which is a local obstacle of social life, is gradually increasing due to the improvement of national income. Moreover, Koreans tend to prefer foods with strong odors such as green onions, garlic, salted fish and kimchi, so there is an urgent need to develop deodorants that effectively eliminate bad breath after eating.

Conventionally, deodorizing effects of removing bad breath are generally known as flavonoids, which are light yellow pigments, and chlorophyll, which are green pigments, which are contained in the leaves of plants. These extracts are extracted by solvent extraction methods. It is used in addition to favorite foods (gum and candy), and among them, deodorant using paulownia and chajeoncho is disclosed in Japanese Patent Publication No. 90-22669 and Japanese Patent Publication No. 90-22672, respectively. Known.

In general, bad breath refers to the smell of exhalation (呼氣) coming out of the mouth around people unpleasant. As described above, bad breath consists of volatile sulfur compounds produced by decomposing epithelial connective tissue, plant residues, and oral bacteria in saliva as protein sources. The main component of these sulfur compounds is methyl mercaptan. : CH ₃ SH), hydrogen sulfide (H ₂ S), dimethyl sulfide (CH ₃ ) ₂ S), and methyl mercaptan, in particular, is known as the main component of the disgusting smell during bad breath.

In addition, in the case of production, as the freshness drops, trimethylamine (Trimethylamine, (CH ₃ ) ₃ N], piperidine (Pipperidine) or δ-aminovaleric acid), which is a fish fish odor, is formed. These volatile amine compounds, especially trimethylamine, form a major part of the malodorous component.

Thus, the present inventors have found that extracting extracts from persimmon leaves and using them as a deodorant resulted in an effort to develop a deodorant which can effectively remove bad breath.

Accordingly, the present invention provides a new use to add an extract solvent to the persimmon leaves to obtain an extract from it to use as a deodorant exhibiting a strong deodorant effect on methyl mercaptan, a major component of bad breath and trimethylamine, a kind of malodor component. The purpose is.

Hereinafter, the present invention will be described in detail.

The present invention is added to 8 parts by weight of an extraction solvent mixed with methanol and water or ethanol and water in a ratio of 1 to 1 part of dried persimmon leaves finely refluxed at a temperature of 20-95 ℃ reflux for 4-24 hours And a deodorant containing distilled extract and concentrated persimmon leaf extract as an active ingredient.

Referring to the present invention in more detail as follows.

In the present invention, the persimmon leaf is finely chopped, but 8 to 12 parts by weight of an extraction solvent mixed with methanol and water or ethanol and water in a ratio of 1 to 1 part by gamping is added for 4 to 24 hours at a temperature of 20-95 ° C. Extracted by reflux and distillation, then juiced, filtered and concentrated.

In this case, the ratio of the extraction solvent to 1: 1 is to extract both the water-soluble and oil-soluble components among the deodorant active ingredients. Also, if the extraction temperature is less than 20 ° C, the extraction yield is low. If the temperature is over 95 ℃, there is a fear of thermal degeneration of the deodorant active ingredient, and if the extraction time is less than 4 hours, there is a problem that less active deodorant is extracted. there is a problem. In this case, if the extraction solvent is used in excess, the extraction efficiency is reduced because of difficulty in concentration.

According to the present invention, reflux and distillation are performed after the extraction solvent is added to obtain an extract by refluxing at reflux for 4 to 24 hours at a temperature of 20 to 95 ° C. using a Reflex Distillator, and the extract is juiced in a juicer to remove residues. After extracting the filtrate and concentrating by vacuum evaporation, persimmon leaf extract is obtained.

The persimmon leaf extract thus obtained can be used as a deodorant by mixing with additives such as cyclo dextrin.

In the present invention, in order to confirm the deodorizing effect on the methyl mercaptan and trimethylamine of the persimmon leaf extract was compared in vitro experiment using gas chromatography and sensory evaluation method using sensory evaluator, as a result deodorant effect Was found to be excellent.

And the residual amount of methyl mercaptan and trimethylamine by persimmon leaf extract by reaction time was generally inferior to green tea extract, which is known to have strong deodorant effect.

As the extraction solvent used in the present invention, water and hydrophilic organic solvents, in particular, alcohols such as methanol, ethanol, glycerin, propylene glycol, ketones such as acetone, and the like are used alone or in combination.

When the persimmon leaf extract obtained in the present invention is used as a deodorant, powder, tablets using a carrier such as liquid, spray type, or dextrin, etc. It can be shape | molded with granules etc. and can be used according to a use. When used as a liquid deodorant, the effective concentration of the deodorant is good in the range of 0.25 ~ 5%, the higher the concentration, the better the deodorizing effect, the sustainability, but the smell of the deodorant itself is not preferred as a deodorant.

In order to prevent volatilization of the deodorant solution and to give an antiseptic effect, alcohol such as glycerin or propylene glycol is usually used as an additive. In addition, when the deodorant is used in a solid form, the deodorant may be mixed with gelatin to make a solid.

Thus persimmon leaf extract obtained in accordance with the present invention is used in addition to gum, candy, soft drinks, deodorant spray to remove bad breath in the mouth, in particular, can be effectively used as a deodorant to remove the odor of the air caused by environmental pollution.

Illustrating the case of using the persimmon leaf extract obtained in the present invention as a deodorant for odor removal is as follows.

1) Dilute persimmon leaf extract with alcohol and make deodorant (消臭 液劑) and sprinkle it on the place where odor occurs.

2) Mix foods directly and mix well before use.

3) Used directly in cosmetics and toothpaste.

4) Used as a deodorant component of deodorizer and deodorizer.

5) In case of removing odor of medicine, etc., it is generally used as a powder and granulated into granules or tablets and put into packaging or storage container.

6) When used as a deodorant powder, it is molded into a suitable form and used for refrigerator with activated carbon.

The use example of the deodorant of this invention is listed next, This use example is not limited only to this (% represents weight%).

Use example 1 (deodorant spray)

Ethanol 49.8%

Glycerin 48%

Fragrance 0.2%

Persimmon Leaf Extract 2.0%

100% of total

Use example 2 (candy)

50% sugar

Starch syrup 34%

Citric acid 1%

Fragrance 0.2%

Persimmon Leaf Extract 0.5%

14.3% of water

100% of total

Example 3 (drinks)

12% sugar

Honey 1%

Drinking stock 0.3%

0.1% fragrance

Persimmon Leaf Extract 1.0%

85.6% of water

100% of total

Hereinafter, the present invention will be described in detail with reference to Examples, but the present invention is not limited by Examples.

Example 1

To 100 g of dried persimmon leaves, 500 g of methanol (99.9%) and 500 g of pure water were added to a 5 L flask container, refluxed, distilled and extracted at a temperature of 20-95 ° C. for 4-24 hours, and then cooled to 30 ° C. Juice with a juicer and filter with 400mesh sieve. 950 g of the filtrate was filtered and concentrated in vacuo at 40 ° C. to obtain 21 g of persimmon leaf concentrate with a solid content of 50%. The extract was used for deodorant experiments (persimmon leaf extract 1).

Example 2

500 g of ethanol (99.9%) and 500 g of water were used instead of 500 g of methanol (99.9%) and 500 g of Example 1, and 21 g of persimmon leaf concentrate was obtained in the same manner as in Example 1 (persimmon leaf extract 2). . (The content ratios of methanol, water, ethanol and water in Examples 1 and 2 are related to the ratio of extract components extracting oil-soluble and water-soluble components among the deodorant active ingredients of persimmon leaves, and are based on the most basic content ratio of 1: 1). It was only used, and the deodorizing effect was similar when the content ratio was changed.)

Comparative example

100 g of dried green tea (2% water content) was pulverized to 50 mesh or less using a grinder, and then 100 g of a solvent containing methanol and water 1: 1 was placed in powdered green tea, and the green tea concentrate (solid content) was prepared in the same manner as in Example 1. 50%) was obtained and used in the deodorization comparison experiment (green tea extract).

Reference Example 1: Sensory Evaluation Experiment

Three extracts, such as persimmon leaf extract 1 obtained in Example 1, persimmon leaf extract 2 obtained in Example 2 and green tea extract obtained in Comparative Example, were used as sensory evaluation samples.

First, 40 ml of distilled water is added to a 100 ml Erlenmeyer flask and methyl mercaptan (99.9%) in gaseous state is injected to make a 2% aqueous solution. In the same manner, 40 ml of distilled water is placed in a 100 ml Erlenmeyer flask and gaseous trimethylamine (99.9%). Was injected into a 15% aqueous solution and used as the standard odor solution (Blank).

Six sensory evaluation agents were added to the above solution by adding 8 g of each of the three extracts for 30 minutes in a 36 ℃ water bath and 30 minutes in a 36 ℃ water bath without extracts. The results of sensory evaluation according to the criteria of the following six-stage odor intensity labeling method are shown in the following Tables 1 and 2.

Six levels of odor intensity notation

Table 1. Sensory evaluation result table for methyl mercaptan

Table 2. Sensory evaluation result table for trimethylamine

Reference Example 2: Deodorizing effect of the extract by in vitro experiment

Take persimmon leaf extract 1, persimmon leaf extract 2, green tea extract 8g each to add water to make 40ml and dissolve well, put each in a 100ml volumetric flask (Volumetricflask) and stirred for 10 minutes in a 36 ℃ water bath. Then, 3 ml of methyl mercaptan or trimethylamine gas, which is an odorous substance, was taken into the above volumetric flask, 0.3 ml of the odor was injected into GC (Gas Chromatography), and the odorous substance and the odorous substance in water were continuously reacted while stirring. After 10 minutes, 15 minutes, 30 minutes, 45 minutes, and 60 minutes, 0.3 ml of each sample was taken from the upper space of the volumetric flask and injected into the GC.

In this case, gas chromatography (Gas Chromatography, shimadzu-9A) with FPD (Flame Photometric Detector) was used to measure the time-dependent decrease of methyl mercaptan after deodorant addition, and the column was TCEP [25%, 1 , 2,3-Tris (2-Cyano ethoxy) propane, L = 3m, Φ = 1 / 8inch] was used, and FID (Flame Ionized Detector) was attached to measure the decrease over time after adding deodorant of trimethylamine. Gas chromatography was used, and the column was diglycerol + TEP + KOH (15 + 15 + 2)% (L = 3m, Φ = 4mm). The GC analysis conditions were as follows. The effect of the deodorant on odorous substances is shown in Table 3 below.

Table 3. Deodorization Effect of Deodorant to Odor

Reference Example 3: Deodorizing Effect of Persimmon Leaf Extract and Green Tea Extract

In general, the green tea extract used as a deodorant was obtained in the same manner as in the comparative example, and the results of in vitro experiments as shown in Reference Example 2 using 4 g (1: 1) of persimmon leaf extract 1 in combination with 4 g of this green tea extract are shown in Table 4. Same as

Table 4. Deodorizing Effect of Persimmon Leaf Extract and Green Tea Extract

Through the above-described examples, comparative examples and reference examples to methyl mercaptan and trimethylamine, two odorous substances extracted from methanol and water (1: 1), ethanol and water (1: 1) from persimmon leaves The results of comparing the deodorant effect by the sensory evaluation method and the in vitro test method are summarized. As shown in the sensory evaluation test results of Tables 1 and 2, the deodorizing effect of the persimmon leaf extract 1 and the persimmon leaf extract 2 is similar to that of the green tea extract. In addition, the deodorizing effect of the two persimmon leaf extracts on methyl mercaptan and trimethylamine was similar to that of the green tea extract, as shown in the in vitro experiments on the reduction of malodorous substances in Table 3.

When using persimmon leaf extract 1 and green tea extract as shown in Table 4 also showed a very strong deodorizing effect by showing the effect of using the extract 1 and green tea extract alone.

Therefore, the persimmon leaf extract extracted from persimmon leaves can be effectively used as a deodorant to remove the odor or in combination with other deodorants can effectively obtain a deodorant effect.

Claims (1)

Deodorant containing persimmon leaf extract extracted from persimmon leaf with methanol and water or ethanol and water as an active ingredient.