KR100797974B1 - Composition to decrease body malodor - Google Patents

Abstract

The present invention relates to a deodorant composition for reducing body odor, and more specifically, non-leaflet extract, root extract, gold silver extract, kill extract, iris extract, ginkgo biloba extract, sesame extract, licorice extract, sewage extract, and macho vinegar extract, It relates to a deodorant composition for reducing body odor comprising at least one plant extract selected from the group consisting of.

The present invention can provide a deodorant composition that can significantly reduce the body odor of the human body, such as liquid odor and foot odor by including a specific plant extract as a deodorant.

Deodorant composition for reducing body odor, plant extract, deodorant

Description

Deodorant composition for body odor reduction {COMPOSITION TO DECREASE BODY MALODOR}

[Industrial use]

The present invention relates to a deodorant composition for reducing body odor, and more particularly, to a body deodorant deodorant composition comprising a plant extract having the effect of significantly reducing the odor of the main volatiles causing unpleasant body odor occurring in the human body It is about.

[Prior art]

Body odor is involved in eccrine sweat (apoccrine sweat), apocrine sweat (sebum), sebum, contaminants, etc., but the cause and smell of the body has different specificities. In the case of the most worrisome odor of the body odor, the odorless afucrine sweat is caused by the decomposition of axillary flora and odor causes. There are many reports on odor-related microorganisms, but it is probable that odor is caused by lipophilic diphtheroid or large colony diphtheroid. The generation of volatile odorous substances after decomposition of the microorganism or microorganism includes lower fatty acids (caproic acid, caprylic acid, isovaleric acid, buttric acid, butyric acid) , Amines, indole, mercaptan, hydrogen sulfide, phosphine, steroids, etc. In particular, isogilfoic acid, steroids among the lower fatty acids, 5 alpha-andro 5α-androst-16-en-3α-ol and 5alpha-androst-16-en-3alpha-one (5α-androst-16-en-3α-one ) Is known to be a major cause.

In the case of foot odor, isogil acetic acid produced by the action of microorganisms on secreted eccrine sweat is known to be a major factor.

Generally, the deodorant for human body refers to a product that removes or prevents body odor generated from the human body such as armpit odor (liquid smell), foot odor (foot smell), sweat odor, and odor smell, and aerosol type, pump type, and roll-on type. It can be used in various forms such as stick, powder, granule, liquid and gel.

The principles of removing the odor from the deodorants are classified into the following four categories.

First, physical deodorization is a method of removing odors by ventilation and diffusion, or adsorbing odors using porous materials such as activated carbon, zeolite, and silica gel. The physical deodorization method is one of the widely used deodorant method has been widely applied to residential deodorant in addition to the human body, when used in the human body is ineffective in terms of feeling.

Second, there is a sensory deodorization method that blocks odors by aromatic substances (fragrances). The sensory deodorization method is a method of blocking odor due to its own fragrance, or it is difficult to maintain the balance of odor and odor in harmony. I can't.

Third, there is a chemical deodorization method that is a method of chemically reacting the deodorant with the odor component to be deodorized by neutralization reaction, addition reaction, condensation reaction, oxidation reaction and the like. The chemical deodorization method can be effectively used for a variety of odor components, there is an inconvenience that requires attention in handling depending on the drug used.

Fourth, there is a biological deodorization method that is a method of fundamentally preventing the cause of odor generation, such as sterilizing bacteria or bacteria causing odor occurrence or preventing corruption. The biological deodorization method has a problem in that a very expected effect cannot be obtained after odor is generated.

As such, all four deodorant methods do not provide perfect deodorization and have been selected and applied according to the purpose of use.

In order to overcome this limited usability, various studies on the main components of the deodorant have been conducted. Among them, the representative research results are to apply the plant extract as the deodorant. Related patent applications include Japanese Patent Publication No. 2000-078158, Japanese Patent Publication No. 1998-327776, Korean Patent Publication No. 1999-058713, Korean Patent Publication No. 2000-002239, Oak Tree and Green Tea Extract Korean Patent Publication No. 1998-000477 using pine needle extract, Korean Patent Publication No. 193-021221 using persimmon leaf extract, Japanese Patent Publication No. 1997-103473 using chamomile extract, Korean Patent Publication No. 2001 -007714, Republic of Korea Patent Publication No. 1992-011521 using flavonoids.                         

However, the above methods have the disadvantage that the effect is limited and not clear in preventing the actual body odor.

The present invention is to provide a deodorant composition for reducing body odor having an excellent deodorizing effect on the human body odor, and additionally less skin irritation in order to solve the problems of the prior art as described above.

In order to achieve the above object, the present invention is one or more from the group consisting of non-leaflet extract, root extract, gold silver coin extract, kill extract, iris extract, ginkgo leaf extract, sheath extract, licorice extract, sewage extract, sesame extract, and machise extract It provides a deodorant composition for reducing body odor comprising 0.0001 to 10% by weight of the selected plant extract.

Hereinafter, the present invention will be described in detail.

The present invention is to provide a deodorant composition comprising a certain amount of various plant extracts excellent in body odor reduction efficacy.

Plant extract used as a deodorant in the present invention is well known to have excellent deodorizing effect without irritation to the skin, due to the characteristics used in the human body. That is, the extracts used in the present invention can be used stably in the human body since all of the side effects such as skin irritation do not occur as compared with the well-known plant extracts used in the conventional deodorant composition.                     

The plant extract used as the deodorant is selected from the group consisting of non-leaf extracts, root extracts, gold and silver extracts, killer extracts, iris extracts, ginkgo biloba extracts, bark extracts, licorice extracts, sewage extracts, sesame extracts, and gusset extracts. It is preferable to use what is used. More preferably, it is preferable to use licorice extract or guchi extract as a deodorant.

The deodorizing effect of the plant extracts is a complex action of neutralization, addition, condensation, adsorption and inclusion of flavonols, flavonols, catechins, polyphenols, amino acids, tannins and organic polymers as main components. The result is.

In the deodorant composition of the present invention, the content of the plant extract may vary slightly depending on the formulation, it is preferably used in 0.0001 to 10% by weight. If the content of the plant extract is less than 0.0001% by weight it is difficult to exert the effect, if it exceeds 10% by weight it is difficult to stabilize the formulation and the smell of the raw material itself may be a problem.

Extraction method of the plant extracts of the present invention according to a conventional method, briefly described as follows. First, the roots, stems and leaves of plants selected from loquat, brown root, gold and silver, kill irises, ginkgo biloba, bark skin, licorice, sewage, eoseongcho, and machi prefecture, and then powder and soaked for 5 days in about 10 times of extraction solvent. After extracting the extracted stock solution, each extract can be obtained through a method such as filtration, concentration and freeze drying.

The extraction solvent used here is purified water, methanol, ethanol, propanol, butanol, glycerol, propylene glycol, 1,3-butylene glycol, methyl acetate, ethyl acetate, benzene, hexane, dimethyl ether, dichloromethane 1 More than one species can be selected and used.

Formulation of the deodorant composition for reducing the body odor of the present invention is aerosol (Stick), Stick (Stick), Roll-On (Pump), Sheet (Sheet), Patch (Patch), Cream (Cream) ), Lotion, gel, powder, soap, and liquid cleaner. The dual aerosol or pump type is the most widely used formulation because of its ease of use and excellent use, but may be applied to the body deodorant composition for reducing the body odor of the present invention.

Hereinafter, the present invention will be described with reference to the following Examples and Comparative Examples. However, these examples are only for illustrating the present invention, and the present invention is not limited thereto.

EXAMPLE

Examples 1-11 and Comparative Examples 1-4

(Production of plant extracts (deodorant))

All natural products used in the test (loquat leaf, brown root, gold and silver, kill, iris, ginkgo biloba, bark skin, licorice, sewage, eosungcho, and machi) are removed from impurities and finely ground using a herbal grinding machine to prepare into uniform powder particles. , 100 g of each beaker was added, and 1000 ml of extraction solvent was added to extract the natural product sufficiently. Water and 70% ethanol were used as the extraction solvent. 70% ethanol extract was prepared by filtration under reduced pressure (Whatman 41, English) to increase the yield and purity of the crude extract extracted by cold soaking at room temperature for 72 hours, and a rotary vacuum evaporator (BUCHI, Switzerland). Each plant extract was prepared by concentrating under reduced pressure until the amount of each extract was 100 ml.

Green tea extracts, persimmon leaf extracts and chamomile extracts of Comparative Examples 1 to 3 were also extracted and obtained in the same manner as in Example. At this time, blank was made into the comparative example 4.

Experimental Example 1

(Marker substance)

Among the substances that have been identified so far, isovaleric acid (Aldrich, USA), a representative substance of foot odor, and 5-androst-16-en-3-one (5-androst-16), a representative substance of liquid odor source -de-3-one, Aldrich, USA) were compared to the degree of deodorization by the gas detection method and sensory evaluation method as follows.

(Gas Detection Pipe Act)

Put 1 ml of deodorant and 1 ml of ethanol 1% (ethanol 1% diluent) into the flask, insert a gas detector tube (No.81L, GASTEC, Japan), seal it completely, and after 30 minutes, gas collector (GV-100S) , GASTEC, Japan) was inhaled for 1 minute, and the change in the color development reagent in the detection tube was measured in ppm.

(Sensory test method)

After 30 minutes elapsed after adding 1 ml of deodorant and 1 ml of 5 alpha-androst-16-en-3-one (ethanol 1% dilution) to the flask, three sensory evaluation specialists The score was averaged after smelling according to the criteria.

score Evaluation standard 0 No smell at all One Smells very weak 2 Low smell 3 The smell is usually 4 Strong smell 5 Very strong odor: In terms of deodorant

Deodorization degree results according to the gas detection tube method and sensory test method are shown in Table 2 below.

division Deodorant Substance Gas detection tube method Sensory test Isogil acetic acid detection amount (ppm) Deodorization rate (%) 5 alpha-androst-16-en-3-one Example 1 Non-leafy Extract 2.9 81 3.0 Example 2 Root Extract 2.4 84 2.7 Example 3 Gold and Silver Extract 3.5 77 3.3 Example 4 Kill Extract 3.2 79 3.3 Example 5 Iris extract 4.2 72 3.0 Example 6 Ginkgo Leaf Extract 2.0 87 2.7 Example 7 Bark Extract 2.7 82 2.0 Example 8 Licorice Extract 0.9 94 2.0 Example 9 Sewage Extract 3.2 79 3.3 Example 10 Eoseongcho Extract 2.6 83 2.7 Example 11 March extract 1.2 90 1.7 Comparative Example 1 Green Tea Extract 6.9 54 4.0 Comparative Example 2 Persimmon Leaf Extract 7.5 50 4.3 Comparative Example 3 Chamomile Extract 8.5 43 4.3 Comparative Example 4 Blank 15 - 5.0 (standard)

As can be seen in Table 2, Examples 1 to 11 according to the present invention shows a high deodorizing effect of 72 to 94%. On the other hand, Comparative Examples 1 to 3 without the deodorant showed a low deodorant effect of 43 to 50%. In addition, the sensory test on 5 alpha-androst-16-en-3-one also showed a low deodorizing effect of at least 4 points in Comparative Examples 1 and 3, while in Examples 1 to 11, 1.7 to 3.7. Showed excellent deodorizing effect. In particular, in the case of Example 8 and Example 11, including licorice extract and portulaca extract, showed a very good deodorizing effect for both body odor causes.                     

(Skin Stimulation Test)

0.1 ml of the extract used in Examples 1 to 11 and Comparative Examples 1 to 3 was closed on the back of 20 subjects using a fin chamber and a scanpore tape for 24 hours. 90 minutes after the next removal, stimulation was determined according to the International Contact Dermatitis Research Group (ICDRG) scale, and the results are shown in Table 3 below.

(Criteria)

(-): No stimulus at all ---------------------- 0 points

(±): very weak redness ---------------------- 1 point

(+): Weak redness --------------------------- 2 points

(++): strong flare -------------------------- 3 points

(+++): very strong redness or edema ----- 4 points

division Deodorant Substance ICDRG scale Example 1 Non-leafy Extract 0.12 Example 2 Root Extract 0.10 Example 3 Gold and Silver Extract 0.08 Example 4 Kill Extract 0.08 Example 5 Iris extract 0.10 Example 6 Ginkgo Leaf Extract 0.14 Example 7 Bark Extract 0.10 Example 8 Licorice Extract 0.04 Example 9 Sewage Extract 0.08 Example 10 Eoseongcho Extract 0.12 Example 11 March extract 0.06 Comparative Example 1 Green Tea Extract 0.12 Comparative Example 2 Persimmon Leaf Extract 0.10 Comparative Example 3 Chamomile Extract 0.06

As shown in Table 3, it can be seen that the plant extracts used in Examples 1 to 11 exhibited low values showing no significant difference in skin irritation compared to the extracts of Comparative Examples 1 to 3, which can be safely used. have.

Experimental Example 2

In order to compare the deodorizing effect of Example 11 and Comparative Example 1, except the LPG, the ingredients and compositions of the contents shown in Table 4 well mixed in a general mixer and put in a can, deodorant by the general method of filling LPG Was prepared.

(unit: %) division Example 11 Comparative Example 1 March extract (ethanol 99% solution) 1.0 - Green tea extract (ethanol 99% solution) - 1.0 ethanol 39 39 LPG Remaining amount Remaining amount

(Smell strength measurement: Sniff test)

In order to evaluate the deodorizing effect of Example 11 and Comparative Example 1, the odor intensity was measured by the following method. Twenty males, 20-40 years old, who are usually considered to have their own liquor and foot odors, are injected twice a day (10 o'clock) in Example 12 and Comparative Example 5 on both sides and feet once a day for two weeks. (16: 00 = 6 hours later, 10:24 hours the next day) A visit was made to evaluate the odor intensity. The evaluation was performed by three well-trained sensory evaluation specialists who performed a sinff test on the subject's armpit and foot scent intensity. The score was scored according to the following criteria. The average was calculated.

Before the test, the degree of liquid immersion of the subjects was measured, and the use sites of Example 12 and Comparative Example 5 were symmetrical with 10 persons each so that there was no left and right deviation. In addition, in order to eliminate the left and right deviation with time, the test was conducted in the second week by changing the order of use of the subject in the second week. The evaluator banned the use of fragrances, limiting odorants, scented soaps or cleaning products that could affect the test during the test period, and separately provided no-added soaps except fragrance and other substances that could affect the test. Only this was used. In addition, for the period during which the evaluation was not possible due to personal circumstances, only the data until the departure was processed statistically, and after the return, the data from the 2nd day of return was used for the statistics. Bounce rates excluded from the statistics were not as high as less than 10%.

In the following evaluation criteria of the evaluator and the evaluator, the expert evaluator who was highly trained (additional training through the sniff test of isogil acetic acid and actual odor smell before evaluation) divided the intensity into six stages. In this case, it was evaluated by dividing into five stages and making the standard easier.

(Based on scoring professional reviewers)

score Evaluation standard 0 No smell at all One Smells very weak 2 Low smell 3 The smell is usually 4 Strong smell 5 Very strong smell

(Evaluation self-evaluation criteria)

The results are shown in Table 5 below, and the lower the value, the better.

division Body parts 6 hours effect (16:00 measurement) 24-hour effect (10 o'clock measurement) base line Example 12 Comparative Example 5 base line Example 12 Comparative Example 5 Professional evaluator Armpit (smell) 3.35 1.57 2.85 2.75 2.23 2.73 Feet 3.57 2.05 3.20 2.45 2.38 2.53 Self-assessment Armpit (smell) - 2.25 3.35 - 2.67 3.40 Feet - 2.41 3.47 - 3.18 3.50

As can be seen in Table 5, in the case of the evaluation by a professional evaluator, Example 12 prepared according to the present invention was confirmed that the effect of significant reduction in odor and foot odor in all cases than Comparative Example 5. However, in the case of the 24-hour effect on foot odor, the measurement result did not show a significant difference between before use and between Example 12 and Comparative Example 5, which is unlikely to have a small difference because most of the subjects wash their feet in the morning unlike the armpits. . Also in the evaluation by the subject's self-evaluation, all the items answered that Example 12 was superior to Comparative Example 5.

In addition, as a result of recognizing the reduction of odor and foot odor of only the severe odor intensity 4 or more, the decrease was more pronounced and the difference between Example 12 and Comparative Example 5 was large.

As described above, the present invention can provide a deodorant composition that can significantly reduce the body odor of the human body, such as liquid odor and foot odor including a specific plant extract as a deodorant.

Claims (5)

In the deodorant composition for body odor reduction, Deodorant composition for reducing body odor comprising a plant extract selected from the group consisting of non-lobe extracts, root extracts, gold coins extracts, kill extracts, iris extracts, ginkgo biloba extracts, velvet extracts and portulaca extracts. The method of claim 1, Deodorant composition for reducing body odor, characterized in that the content of the plant extract is 0.0001 to 10% by weight. The method of claim 1, Formulation of the deodorant composition may be aerosol, stick, roll-on, pump, sheet, patch, cream, lotion, Deodorant composition for reducing body odor, characterized in that selected from the group consisting of gel (Gel), powder (Powder), soap, and liquid detergent. According to claim 1, wherein the plant extract Purified non-leaflets, roots, gold and silver, kill, pulverize and pulverize the roots, stems and leaves of plants selected from the group consisting of irises, ginkgo biloba, bark skins and gusset, purified water, methanol, ethanol, propanol, butanol, glycerol, propylene glycol Extract by cooling in an extraction solvent selected from one or more selected from the group consisting of 1,3-butylene glycol, methyl acetate, ethyl acetate, benzene, hexane, dimethyl ether, and dichloromethane, and then extract, concentrate and freeze the extract. Deodorant composition for body odor reduction characterized in that it is prepared by drying. The method of claim 1, Licorice extract, sewage extract and deodorant composition for reducing the harvest further comprising at least one plant extract selected from the group consisting of fish extract.