KR970007197B1 - Lakes method for coloring material extracted from phellodendron amurense ruprecht - Google Patents

Abstract

The invention relates to a process for obtaining a yellow pigment used for cosmetic compositions which exhibit excellent color stability, spreadability, light stability, skin feel and stability against acids/base. The yellow pigment is produced by the following steps: dissoving berberine (a pigment extracted from phellodendron) in alcohol, water or their mixture; mixing and agitating the solution with water-soluble and animal collagen solution with pH7.0-9.0 to absorb berberine in the collagen; immobilizing the absorbed berberine by adding polyvalent metal ion to form a lake.

Description

Laking Method of Pigment Extracted from Yellow Tree

The present invention relates to a method of rakeling a BERBERINE pigment, which is a pigment extracted from a yellow-white tree, and more specifically, by absorbing and quenching the burned pigment in an aqueous soluble animal collagen treated with alkali, color effect, feeling, It is related with the method of obtaining the yellow pigment | dye which is a pigment for cosmetics which is excellent in pigment dispersibility, photostability, skin dye excipient, and stability to acid alkali.

Hwangbaek tree is a deciduous tree growing in mountain valleys with high soil moisture or high humidity in all areas of Korea, Japan, China, etc., and is widely used as a wince for herbal medicines. It is used as an extinguishing agent and used as a potion for abdominal pain in the private sector, and as a face wash such as eye redness and conjunctivitis.

The present inventors have conducted research to improve the dispersibility and skin instability of acid, alkali and light, which are disadvantages of natural pigments, and to improve dispersibility while maintaining excellent color of the burberry pigment itself. The present invention has been found to be accomplished by adsorbing and immobilizing a water-soluble collagen to achieve the above object as well as the effect of delaying skin aging due to water-soluble collagen.

It is therefore an object of the present invention to provide a method for raking the burberry pigment.

Another object of the present invention is to adsorb the aqueous solution to the water-soluble animal collagen by mixing and stirring a solution of the yellow-white extraction pigment Burberry in alcohol, water or a mixture thereof and a water-soluble animal collagen solution adjusted to pH 7.0-9.0 It is to provide a method for lakekwang yellow- extraction pigments, characterized in that the immobilized by the addition of a metal ion of a polyvalent metal salt.

Hereinafter, the present invention will be described in more detail.

According to the method of the present invention, the Burberry's raking is made by adsorbing collagen, which is an animal protein having a polypeptide structure, by alkali treatment to adsorb the yellowish white-extracting pigment (hereinafter referred to as Burberry), followed by raking and immobilization. It is about a method. According to the method of the present invention, the instability to acids, alkalis and light is improved while maintaining the excellent color of the burberry pigment itself, the skin dyeability is excluded, the dispersibility in the water and oil phases is excellent, and the usability is also excellent. On the other hand, yellowish lake-burning burberry pigment | dye which also shows the skin aging delay effect by water-soluble animal collagen can be obtained.

Collagen is a protein in the body that serves as an index of skin aging. Collagen in young people contains a lot of moisture, so it maintains elastic and smooth skin condition, but as it ages, the cross-linkage between collagen fibers increases and the water content decreases, which leads to rough and wrinkled skin. Therefore, the Burberry pigment | dye which was laked using the water-soluble animal collagen which has a polypeptide structure also exhibits the effect of delaying skin aging by collagen.

As the water-soluble animal collagen that can be used in the present invention, atherocollagen extracted from the skin of a young calf, atherocollagen SS in which hydrogen of the amino group of the atherocollagen is substituted with succinyl group, and hydrogen of the amino group of atherocollagen are previously It can be exemplified by atherocollagen MS (produced by Koken, Japan) obtained by substituting a stoyl group and then replacing another hydrogen with a succinyl group. These products have a skin-activating effect and have a good moisturizing effect as a colorless, odorless and clear solution.

The method of the present invention is described in detail as follows.

The yellowish white-extracted pigment is sliced into 4-5mm of yellow white, and 5L of 70% ethanol aqueous solution is added to 1kg of yellow white, extracted for 3 hours in a water bath. The extract is filtered and concentrated, and then dissolved in 70% ethanol aqueous solution for 1 week. It is prepared by aging.

The burberry is added to alcohols such as ethanol, propanol, isopropanol, water or a mixture thereof to stir well to form a saturated solution. On the other hand, a small amount of alkali, for example, sodium hydroxide, is added to the saturated solution, and the collagen aqueous solution whose pH is adjusted to the isoelectric point, that is, 7.0 to 9.0 is added to the saturated solution, followed by stirring to react with the burberry.

The mixture is then subjected to an adsorption process. The adsorption process involves the addition of water-soluble polyvalent metal salts, such as calcium chloride, aluminum sulfate, and barium chloride, which can undergo ion-bonding reactions in the same amount as the salts of burberry and collagen. After melting and dissociating, the mixture may be added to cause the dissociated metal ions to undergo an ionic bond reaction with unreacted ions in the collagen that is ionically bonded to the burberry, thereby fixing the collagen and the burberry. The resulting additives can then be filtered, washed and dried to give the laked pigment.

The solvent used to dissolve the burberry in the process of the present invention is preferably a mixture of water and alcohols, in which case the mixing ratio between them is in the range of 70:30 to 30:70.

Moreover, the equivalent ratio of burberry to water-soluble animal collagen is in the range of about 1: 1 to 5, and the equivalent ratio of water-soluble animal collagen and water-soluble polyvalent metal salt is in the range of about 1: 1.

The laked yellow pigment produced by the method of the present invention has the following advantages over the conventional yellowish white-extracted pigments: Firstly, when the burberry itself is dissolved in water or an organic solvent, it is dark and dull undesirable color. The pigmented lake has a vivid and beautiful color. Second, the Burberry pigment rake by the present invention is excellent in water dispersibility and oil dispersibility compared to the unlaked Burberry, and there is no phenomenon that the pigments are aggregated. Third, the rake pigmented pigment produced by the method of the present invention has no color change compared to the unburned burberry. Fourth, it does not dissolve in oil or water and does not dye on the skin. Fifth, unlike the extracted Burberry, which is very weak to light, the raked Burberry pigment of the present invention is very stable against sunlight. Sixth, collagen has a aging retardation effect and a unique feeling of use, it is soft and skin-friendly.

Hereinafter, the present invention will be described in more detail with reference to various examples, but the present invention is not limited only to these examples.

Example 1

1 g of Burberry was added to 300 g of a mixture of water and ethanol having a weight ratio of 70:30, and dissolved well. In addition, 20 g of a commercially available water-soluble animal collagen (2%; atherocollagen SS: manufactured by Koken, Japan) was dispersed in 200 g of water, and a small amount of caustic soda was added to have a pH of about 80. The two solutions were mixed and stirred well. ₄ g of aluminum sulfate (Al ₂ (SO ₄ ) ₃ , 16-8 H ₂ O) was added to excess warm water (50 cc) and stirred for about 30 minutes, followed by mixing with the pre-stirred pigmented collagen. The resulting precipitate was filtered, washed and dried by addition of a solution to prepare a lake of discarded pigment.

Experimental Example

The physical properties of the laked Burberry pigment of the present invention prepared as in the above Example and the conventional Burrard pigment, Siconin and Red No. 202 were measured by the following method for the items listed in Table 1 below.

(1) Light stability: After dispersing a small amount of sample in an aqueous solution containing a small amount of polyoxyethylene sorbitan lauryl ester having a pH of 7.0, and changing the color by continuously leaving the sample dispersed in sun and shade for several days. L ^*, a ^* and b ^*) to guard spectrometer II colorimeter (color Spectrograd ^TM II system; using a Pacific Scientific Co .; USA), it is measured, ΔE values are calculated according to the following results: ΔE ≤ 1.0, extremely good (◎), 1.0 ΔE ≤ 2.0 good (○), 2.0 ΔE ≤ 2.5 normal (△), 2.5 ΔE bad (×) After the evaluation, the results are shown in Table 1.

(2) Stability against acid alkali: After appropriately placing the sample in the above aqueous solution with pH 4.0-10.0 and shaking to disperse, the color change (L ^* , a ^* and b ^* ) of the sample dispersion was measured using a SparrowGuard ^TM II color system. (Spectrograd ^™ II color system; Pacific Scientific Co .; USA) and measured ΔE values at pH 4.0 and at pH 10.0 ΔE0.5 for very good (◎), 5.0≤ΔE≤1.0 for good (○), 1.0ΔE≤1.5 for normal (△), 1.5ΔE for poor (×) The results are shown in Table 1 below.

(3) Stability against Skin Dyeing: Color difference after washing for 2 hours after applying small amount to the skin by dispersing the sample in dissolvable or dispersible medium in equal amounts each (L ^* , a ^* and b ^* ; ΔE = (ΔL ^* ) ² + (Δa ^* ) ² + (Δb ^* ) ² ) was measured using chroma meta (color difference analyzer, Minolta, USA) and, depending on the ΔE value, extremely good for ΔE1.0 (◎) After evaluation as good ((circle)) when 1.0 <= (DELTA) E <= 2.0, normal ((triangle | delta)) when 2.0 (DELTA) E <= 4.0, and bad (x) when 40 (DELTA) E, the result is shown in Table 1.

(4) Phase separation: The sample was dispersed in water or oil under the same conditions, and the degree of dispersion was observed under a microscope. The result was evaluated according to the following evaluation criteria and the results are shown in Table 1.

[Evaluation standard]

◎: extremely good, ○: good, △: normal, ×: poor.

TABLE 1

From the results of Table 2, it can be seen that the laked-burberry pigment prepared by the method of the present invention is superior to the conventional pigments in light stability, stability against acids and alkalis, exclusion and dispersibility in skin dyeing.

Claims (4)

After mixing and stirring alcohol solution, water or mixture thereof, the solution of Burberry, which is a white-white extract pigment, and water-soluble animal collagen solution adjusted to pH 7.0-9.0, adsorbing the Burberry to water-soluble animal collagen, and then adding polyvalent metal salt A method for lakeking a white-white extract pigment, characterized by immobilization. The method according to claim 1, wherein the mixing ratio of water and alcohols is 70: 30-30: 70. The method according to claim 1, wherein the equivalence ratio of the yellowish white-extracted pigment to the water-soluble animal collagen is 1: 1-5. The method according to claim 1, wherein the equivalent ratio of water-soluble animal collagen and water-soluble polyvalent metal salt is 1: 1.