KR950702182A - 면역억제 활성를 갖는 신규항생물질 데라미노마이신류와 이들의 제조방법 - Google Patents

면역억제 활성를 갖는 신규항생물질 데라미노마이신류와 이들의 제조방법

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Publication number
KR950702182A
KR950702182A KR1019940704690A KR19940704690A KR950702182A KR 950702182 A KR950702182 A KR 950702182A KR 1019940704690 A KR1019940704690 A KR 1019940704690A KR 19940704690 A KR19940704690 A KR 19940704690A KR 950702182 A KR950702182 A KR 950702182A
Authority
KR
South Korea
Prior art keywords
deraminomycin
manufacturing
same
immunosuppressive activity
new antibiotic
Prior art date
Application number
KR1019940704690A
Other languages
English (en)
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP10492193A external-priority patent/JP3386842B2/ja
Application filed filed Critical
Publication of KR950702182A publication Critical patent/KR950702182A/ko

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/34Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/36Oxygen or sulfur atoms
    • C07D207/382-Pyrrolones
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/34Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/36Oxygen or sulfur atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56Ring systems containing three or more rings
    • C07D209/96Spiro-condensed ring systems
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/10Nitrogen as only ring hetero atom

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
KR1019940704690A 1992-06-23 1994-12-22 면역억제 활성를 갖는 신규항생물질 데라미노마이신류와 이들의 제조방법 KR950702182A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP18740392 1992-06-23
JP10492193A JP3386842B2 (ja) 1993-04-08 1993-04-08 Mj202−72f3物質の新規エステル
PCT/JP1993/000845 WO1994000430A1 (en) 1992-06-23 1993-06-22 Novel antibiotics with immunosuppressive activity, delaminomycins, and production thereof

Publications (1)

Publication Number Publication Date
KR950702182A true KR950702182A (ko) 1995-06-19

Family

ID=26445286

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019940704690A KR950702182A (ko) 1992-06-23 1994-12-22 면역억제 활성를 갖는 신규항생물질 데라미노마이신류와 이들의 제조방법

Country Status (6)

Country Link
US (1) US5527820A (ko)
EP (1) EP0647625A1 (ko)
KR (1) KR950702182A (ko)
AU (1) AU675651B2 (ko)
CA (1) CA2138542A1 (ko)
WO (1) WO1994000430A1 (ko)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0677513B1 (en) * 1994-04-15 1999-08-18 Takeda Chemical Industries, Ltd. Octahydro-2-naphthalenecarboxylic acid derivative, its production and use
US20030220234A1 (en) * 1998-11-02 2003-11-27 Selvaraj Naicker Deuterated cyclosporine analogs and their use as immunodulating agents
DE50008094D1 (de) * 2000-01-10 2004-11-11 Jung Guenther Tetramsäure-Derivate zur Verwendung in Medizin und Lebensmitteltechnologie
DE60234057D1 (de) 2001-07-25 2009-11-26 Raptor Pharmaceutical Inc Zusammensetzungen und verfahren zur modulation des transports durch die blut-hirn-schranke
KR100982466B1 (ko) * 2001-10-19 2010-09-16 이소테크니카 인코포레이티드 시클로스포린 유사체의 합성
EP1889198B1 (en) 2005-04-28 2014-11-26 Proteus Digital Health, Inc. Pharma-informatics system
WO2008036682A2 (en) 2006-09-18 2008-03-27 Raptor Pharmaceutical Inc. Treatment of liver disorders by administration of receptor-associated protein (rap)-conjugates
EP2427178B1 (en) 2009-05-06 2023-01-04 Laboratory Skin Care, Inc. Dermal delivery compositions comprising active agent-calcium phosphate particle complexes and methods of using the same
US20120077778A1 (en) 2010-09-29 2012-03-29 Andrea Bourdelais Ladder-Frame Polyether Conjugates

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8430455D0 (en) * 1984-12-03 1985-01-09 Fujisawa Pharmaceutical Co Fr-900506 substance
EP0358508A3 (en) * 1988-09-08 1991-03-20 Merck & Co. Inc. Novel immunosuppressant compound
CH678855A5 (ko) * 1988-11-29 1991-11-15 Sandoz Ag
JPH04187403A (ja) 1990-11-21 1992-07-06 Hitachi Koki Haramachi:Kk 木工用かんな盤におけるかんな刃取付方法

Also Published As

Publication number Publication date
US5527820A (en) 1996-06-18
EP0647625A1 (en) 1995-04-12
AU4357193A (en) 1994-01-24
CA2138542A1 (en) 1994-01-06
EP0647625A4 (ko) 1995-04-26
AU675651B2 (en) 1997-02-13
WO1994000430A1 (en) 1994-01-06

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SUBM Surrender of laid-open application requested