KR950013505A - Percutaneous Absorption Adhesive for Acne Treatment - Google Patents

Abstract

The present invention provides a percutaneous absorption type suspending agent that can effectively treat or prevent acne by absorbing or adsorbing sebum through a transdermal absorption adhesive system, thereby allowing acne treatment to be administered. It is characterized by consisting of an active ingredient layer consisting of an adsorbent and an acne treatment drug, an exposed part protective layer and a release film or release paper. Alternatively, the pressure-sensitive adhesive of the present invention may have a multi-layered structure in which the active ingredient layer consists of a pressure-sensitive adhesive layer, an absorbent layer for absorbing sebum components, and an acne treatment drug layer. As described above, the percutaneous absorption type adhesive agent of the present invention can effectively treat acne by treating the acne while adhering to the skin continuously or absorbing sebum, and also has low skin irritation.

Description

Percutaneous Absorption Adhesive for Acne Treatment

Since this is an open matter, no full text was included.

Figure 1 shows an example of the adhesive sheet for acne treatment having a monolayer structure according to the present invention,

2 shows an example of an acne treatment adhesive sheet having a multilayer structure according to the present invention.

Claims (10)

Percutaneous absorption type pressure-sensitive adhesive for the treatment or prevention of acne, characterized in that the pressure-sensitive adhesive, an absorbent for absorbing sebum components and an active ingredient layer consisting of an acne treatment drug, an exposed portion protective layer, and a release film or release paper. The percutaneous absorption type adhesive according to claim 1, wherein the active ingredient layer has a multilayer structure consisting of an adhesive layer, an adsorbent layer for absorbing sebum components, and an acne treatment drug layer. The method of claim 1. The pressure sensitive adhesive is composed of an acrylic polymer adhesive, a silicone pressure sensitive adhesive, a synthetic or natural rubber pressure sensitive adhesive, and a hydrophilic pressure sensitive adhesive that can adhere to the skin. The acrylic pressure sensitive adhesive is an aliphatic ester of acrylic acid and methacrylic acid, an aliphatic vinyl ether, and an ester. It is a single or copolymer consisting of monomers selected from acrylamide, urethane, etc., wherein the silicone resin pressure sensitive adhesive is a pressure sensitive adhesive made of polydimethylsiloxane resin and silicate rubber, and the rubber pressure sensitive adhesive is made of natural rubber, polyisoprene, polyisobutylene, and polyvinyl ether. , Polyurethane, polybutadiene, styrene-butadiene copolymer, styrene-isoprene copolymer, styrene-isoprene-butylene block copolymer, and the hydrophilic adhesive agent is water-soluble such as polyacrylic acid, gelatin sodium carboxymethyl cellulose Percutaneous absorption type pressure-sensitive adhesive, characterized in that consisting of a resin, polyhydric alcohol and water. The method of claim 1, wherein the adsorbent is capable of absorbing or adsorbing sebum components, clay minerals such as talc, cowlin, mica, sericite, bentonite, silicic acid, calcium silicate, magnesium silicate, titanium oxide, iron oxide, Magnesium oxide, zinc oxide, titanium dioxide, calcium carbonate, magnesium carbonate, silica powder, white pigments such as alumina and silica gel, metal soaps such as aluminum stearate, inorganic adsorbents such as carbon black and graphite, and natural and artificial or synthetic fibers It is an organic adsorbent such as hollow fiber, starch, and the like, or a mixture of two or more kinds, and its content is 0.1 to 70% by weight, percutaneous absorption type pressure-sensitive adhesive. The non-woven fabric of claim 1, wherein the exposed portion protective layer is made of polyester, rayon, orlon, cellulose, polypropylene, polyether, polyolefin or cotton or a mixture thereof or a polypropylene, polyurethane, poly Percutaneous absorption type pressure-sensitive adhesive, characterized in that the porous film made of vinyl alcohol, polyolefin, polyethylene. The method of claim 1, wherein the acne treatment drug is benzoylperoxabenzoylperoxide, retinoic acid, azelaic acid, hydroquinone, metronidazole, keratin peeling drugs such as resorcinol, sulfur, salicylic acid, chixosolone, arisomycin, clindamycin, Antibiotics such as tetracycline, fusidic acid, derivatives or salts thereof, benzethonium chromide, benzalkonium chloride, chlorhexidine gluconate and dihydrochloride, isopropylmethylphenol, trichlorocarbanilide, triclosan, nuxamidine and the like Percutaneous absorption type pressure-sensitive adhesive, characterized in that the content of the single or two or more selected from antibacterial agents and the like as a mixture of 0.01 to 30% by weight. 4. The percutaneous absorption type adhesive according to claim 3, wherein the pressure-sensitive adhesive is a non-crosslinkable acrylate-based and rubber-based adhesive. The method of claim 4, wherein the adsorbent is hydrophobic colloidal silica and magnesium oxide when the content is 1 to 30% by weight. The transdermal absorption adhesive according to claim 5, wherein the exposed portion protective layer is a nonwoven fabric or a porous film. The drug for treating acne is salicylic acid, resorcinol, or a combination of renochinol monoacetate and sulfur, or a combination of sulfur and resorcinol monoacetate and an antibacterial agent, the content of which is 0.1 to 20% by weight. Percutaneous absorption type adhesive. ※ Note: The disclosure is based on the initial application.