KR950000159A - Use of attenuated Pseudomonas aeruginosa CFCPA 30720 for the manufacture of a therapeutic and prophylactic vaccine for Pseudomonas aeruginosa infections - Google Patents
Use of attenuated Pseudomonas aeruginosa CFCPA 30720 for the manufacture of a therapeutic and prophylactic vaccine for Pseudomonas aeruginosa infections Download PDFInfo
- Publication number
- KR950000159A KR950000159A KR1019930010276A KR930010276A KR950000159A KR 950000159 A KR950000159 A KR 950000159A KR 1019930010276 A KR1019930010276 A KR 1019930010276A KR 930010276 A KR930010276 A KR 930010276A KR 950000159 A KR950000159 A KR 950000159A
- Authority
- KR
- South Korea
- Prior art keywords
- pseudomonas aeruginosa
- attenuated
- purified
- cfcpa
- agent
- Prior art date
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/104—Pseudomonadales, e.g. Pseudomonas
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/40—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum bacterial
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Immunology (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Dermatology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicinal Preparation (AREA)
- Peptides Or Proteins (AREA)
Abstract
본 발명은 피셔―데블린 면역형태에 따라 타입 3의 녹농균을 순수하게 분리하여 반복적으로 순화시킴으로써 약독화시켜 수득되는 신규의 안전한 약독화 녹농균주 CFCPA 30720(KCCM 10031)의 녹농균 감염증 치료제 및 예방용 백신의 제조를 위한 용도에 관한 것이다.The present invention provides a novel safe and attenuated Pseudomonas aeruginosa CFCPA 30720 (KCCM 10031) obtained by attenuating by purely separating and repeatedly purifying Pseudomonas aeruginosa of type 3 according to the Fischer-Deblin immunomorphology of a vaccine for the treatment and prevention of Pseudomonas aeruginosa infections. It relates to a use for the production.
본 발명에서 이용되는 약독화 녹농균주 CFCPA 30720(KCCM 10031)는 독성이 없이 안전하며, 그의 세포벽 단백질 성분도 안전하면서도 우수한 항체 생성능을 나타내고, 또한 이들로부터 구성되는 본 발명에 따르는 녹농균 감염 예방 백신 및 녹농균 감염증 치료제는 피셔 면역형 3뿐 아니라 6의 녹농균주에 대해서도 탁월한 교차방어 능력을 나타낸다.The attenuated Pseudomonas aeruginosa CFCPA 30720 (KCCM 10031) used in the present invention is safe without toxicity, its cell wall protein component is safe and shows excellent antibody production ability, and also comprises a Pseudomonas aeruginosa infection prevention vaccine and Pseudomonas aeruginosa infection according to the present invention. Therapeutic agents show excellent cross-protective ability against Pseudomonas aeruginosa strains as well as Fischer immunotype 3.
Description
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음Since this is an open matter, no full text was included.
Claims (9)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
KR1019930010276A KR970001705B1 (en) | 1993-06-07 | 1993-06-07 | Psedomonas infection preventing vaccines using attenuated pseudomonas cfcpa 30720 |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
KR1019930010276A KR970001705B1 (en) | 1993-06-07 | 1993-06-07 | Psedomonas infection preventing vaccines using attenuated pseudomonas cfcpa 30720 |
Publications (2)
Publication Number | Publication Date |
---|---|
KR950000159A true KR950000159A (en) | 1995-01-03 |
KR970001705B1 KR970001705B1 (en) | 1997-02-14 |
Family
ID=19356962
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
KR1019930010276A KR970001705B1 (en) | 1993-06-07 | 1993-06-07 | Psedomonas infection preventing vaccines using attenuated pseudomonas cfcpa 30720 |
Country Status (1)
Country | Link |
---|---|
KR (1) | KR970001705B1 (en) |
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1993
- 1993-06-07 KR KR1019930010276A patent/KR970001705B1/en not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
KR970001705B1 (en) | 1997-02-14 |
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Payment date: 20080626 Year of fee payment: 12 |
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