KR940014802A - Method for preparing vancomycin using wheat gluten and soybean meal in fermentation - Google Patents
Method for preparing vancomycin using wheat gluten and soybean meal in fermentation Download PDFInfo
- Publication number
- KR940014802A KR940014802A KR1019920027569A KR920027569A KR940014802A KR 940014802 A KR940014802 A KR 940014802A KR 1019920027569 A KR1019920027569 A KR 1019920027569A KR 920027569 A KR920027569 A KR 920027569A KR 940014802 A KR940014802 A KR 940014802A
- Authority
- KR
- South Korea
- Prior art keywords
- vancomycin
- soybean meal
- wheat gluten
- fermentation
- present
- Prior art date
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/44—Preparation of O-glycosides, e.g. glucosides
- C12P19/60—Preparation of O-glycosides, e.g. glucosides having an oxygen of the saccharide radical directly bound to a non-saccharide heterocyclic ring or a condensed ring system containing a non-saccharide heterocyclic ring, e.g. coumermycin, novobiocin
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- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Wood Science & Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Microbiology (AREA)
- General Chemical & Material Sciences (AREA)
- Biotechnology (AREA)
- Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
Abstract
본 발명은 한균작용이 우수한 글라이코펩타이드계의 항생물질인 반코마이신의 제조방법에 관한 것이다.The present invention relates to a method for producing vancomycin, which is an antibiotic of glycopeptides having excellent bacteriostatic action.
본 발명에서는 노르카디아 오리엔탈리스를 개량하여 반코마이신의 생산을 높일 수 있는 변이주를 이용하여 발효배지내에 비교적 저가의 질소원인 밀글루텐과 대두박을 적정 농도로 사용하여 배양액중 반코마이신 농도를 크게 증가시킴을 특징으로 한다.In the present invention, by using a mutant strain that can improve the production of vancomycin by improving the Nordicia orientalis, using wheat gluten and soybean meal, which are relatively inexpensive nitrogen sources, in the fermentation medium, the concentration of vancomycin in the culture solution is greatly increased. do.
Description
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음Since this is an open matter, no full text was included.
Claims (1)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
KR92027569A KR960009067B1 (en) | 1992-12-31 | 1992-12-31 | Preparation process of vancomyun by cultivation |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
KR92027569A KR960009067B1 (en) | 1992-12-31 | 1992-12-31 | Preparation process of vancomyun by cultivation |
Publications (2)
Publication Number | Publication Date |
---|---|
KR940014802A true KR940014802A (en) | 1994-07-19 |
KR960009067B1 KR960009067B1 (en) | 1996-07-10 |
Family
ID=19348777
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
KR92027569A KR960009067B1 (en) | 1992-12-31 | 1992-12-31 | Preparation process of vancomyun by cultivation |
Country Status (1)
Country | Link |
---|---|
KR (1) | KR960009067B1 (en) |
-
1992
- 1992-12-31 KR KR92027569A patent/KR960009067B1/en not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
KR960009067B1 (en) | 1996-07-10 |
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