KR940013526A - Method for preparing fractions with vasodilatation from sphincter muscle - Google Patents

Method for preparing fractions with vasodilatation from sphincter muscle Download PDF

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Publication number
KR940013526A
KR940013526A KR1019920025288A KR920025288A KR940013526A KR 940013526 A KR940013526 A KR 940013526A KR 1019920025288 A KR1019920025288 A KR 1019920025288A KR 920025288 A KR920025288 A KR 920025288A KR 940013526 A KR940013526 A KR 940013526A
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KR
South Korea
Prior art keywords
sphincter muscle
vasodilatation
nonpolar solvent
sphincter
nonpolar
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KR1019920025288A
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Korean (ko)
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KR100238110B1 (en
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곽의종
한창균
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이승동
주식회사 선경인더스트리
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Priority to KR1019920025288A priority Critical patent/KR100238110B1/en
Publication of KR940013526A publication Critical patent/KR940013526A/en
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Publication of KR100238110B1 publication Critical patent/KR100238110B1/en

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/42—Cucurbitaceae (Cucumber family)
    • A61K36/428—Trichosanthes

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  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Biotechnology (AREA)
  • Botany (AREA)
  • Medical Informatics (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Steroid Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Compounds Of Unknown Constitution (AREA)

Abstract

본발명은 괄루근으로부터 혈관이완능이 있는 분획을 제조하는 방법에 관한 것으로서, 더욱 상세하게는 한 약재로 사용되는 괄루근(천화분)으로부터 유화성분을 알콜수용액 및 비극성용매로 추출하여 혈관이완능이 있는 괄루근 분획을 간단한 방법으로 제조하는 방법에 관한 것이다.The present invention relates to a method for producing a fraction with vasodilatation ability from the sphincter muscle, more specifically, an extract from the sphincter muscle (hypothelium) used as a medicinal herb with an alcoholic solution and a nonpolar solvent It relates to a method for preparing the lugeun fraction by a simple method.

Description

괄루근으로부터 혈관이완능이 있는 분획의 제조방법Method for preparing fractions with vasodilatation from sphincter muscle

본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음As this is a public information case, the full text was not included.

제1도는 본발명의 실시예 1에서 얻어진 혈관이완화합물 분획의 박층크로마토그래피(TLC)의 데이타이다.1 is data of thin layer chromatography (TLC) of the vasorelaxant fraction obtained in Example 1 of the present invention.

Claims (3)

잘게 마쇄된 괄루근을 비극성용매로 추출, 여과하여 지질 등의 비극성물질을 제거한후 메탄올의 수용액으로 추출한후 세포잔사를 제거하고, 그 상등액을 농축하여 수용액상으로 만든후 비극성용매로 불순물을 제거한 다음, 여액을 수포화부탄올로 층분리하고 증류수로 세척하여 제조하는 것을 특징으로 하는 괄루근으로부터 혈관이완능이 있는 분획을 제조하는 방법.Finely crushed sphincter muscles were extracted and filtered with a nonpolar solvent to remove nonpolar substances such as lipids, extracted with an aqueous solution of methanol, cell residues were removed, the supernatant was concentrated to an aqueous solution, and impurities were removed with a nonpolar solvent. , The method for producing a fraction with vascular relaxation ability from the sphincter muscle, characterized in that the filtrate is separated by layer with saturated butanol and washed with distilled water. 제1항에 있어서, 상기 괄루근 추출시 사용되는 비극성용매는 헥산, 클로로포름, 디클로로메탄임을 특징으로 하는 괄루근으로부터 혈관이완능이 있는 분획을 제조하는 방법.The method of claim 1, wherein the non-polar solvent used for extracting the sphincter muscle is hexane, chloroform, dichloromethane. 제1항에 있어서, 상기 불순물 제거시 사용되는 비극성용매는 클로로포름, 디클로로메탄, 사염화탄소 또는 벤젠임을 특징으로 하는 괄루근으로부터 혈관이완능이 있는 분획을 제조하는 방법.The method of claim 1, wherein the nonpolar solvent used to remove the impurity is chloroform, dichloromethane, carbon tetrachloride, or benzene. ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.※ Note: The disclosure is based on the initial application.
KR1019920025288A 1992-12-23 1992-12-23 Preparation method of fraction from trichosanthes radix showing bloodmuscle relaxation KR100238110B1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
KR1019920025288A KR100238110B1 (en) 1992-12-23 1992-12-23 Preparation method of fraction from trichosanthes radix showing bloodmuscle relaxation

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
KR1019920025288A KR100238110B1 (en) 1992-12-23 1992-12-23 Preparation method of fraction from trichosanthes radix showing bloodmuscle relaxation

Publications (2)

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KR940013526A true KR940013526A (en) 1994-07-15
KR100238110B1 KR100238110B1 (en) 2000-02-01

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KR1019920025288A KR100238110B1 (en) 1992-12-23 1992-12-23 Preparation method of fraction from trichosanthes radix showing bloodmuscle relaxation

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100416400B1 (en) * 2001-02-14 2004-01-31 우원홍 Composition containing extracts from dried roots of Trichosantes kirilowii maxim for external application and skin-whitening and process for preparation thereof

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