KR940011444B1 - Process for the preparation of ampoule - Google Patents

Abstract

The ampoule for storing and keeping an injection is manufactured by; heating and drawing longitudinally a glass tube (1); forming head and neck portions of the ampoule; dividing the glass tube into two to heat the interface between elongated and unelongated parts, the ampoule being formed with the lower part of the divided glass; drawing a cutting line on the circumference of end part of the amploule; heating the cutting line to be weak; cutting along cutting line to apply a shock or a vibration; coating the neck portion of the ampoule with a pigment to be easy to cut afterwards; printing volume and name of the injection and producer on surface of the ampoule; and heating the amploule to infiltrate the coated pigment into the glass and to strengthen the elongated part.

Description

Manufacturing method of ampoule

Figure 1 shows the heating step of the manufacturing process of the ampoule,

Figure 2 shows the tensioning process of the ampule manufacturing process,

FIG. 3 shows jupiter shaping during the production of ampoules,

4 shows a separation process in the manufacturing process of the ampoule,

Figure 5 shows the transfer process during the manufacturing process of the ampoule,

6 shows a cutting process during the manufacturing process of the ampoule,

Figure 7 shows the heating step of the manufacturing process of the ampoule,

8 shows a cutting process during the manufacturing process of the ampoule,

9 shows an edge heating process in the manufacturing process of the ampoule,

10 shows the pigment coating process in the ampule manufacturing process,

11 shows a printing process during the manufacturing process of the ampoule,

Figure 12 shows the heat treatment process of the ampule manufacturing process,

FIG. 13 illustrates a process of heating an upper glass tube and an upper ampoule upper heating process during an ampule manufacturing process.

Figure 14 shows the bottom surface processing process of the glass tube and the upper opening process of the ampoule during the manufacturing process of the ampoule,

Figure 15 shows the inlet molding process of the ampule manufacturing process.

The present invention relates to a method of manufacturing an ampoule (Ampoule), which is a glass container for storing and storing a liquid injection drug.

Ampoules are containers of injections that treat disease and require complete sterility and complete dust free. Therefore, careful consideration and considerable attention are required in the manufacturing process.

However, in the manufacturing process of the conventional ampoule, since the foreign material is likely to enter the ampoule in the manufacturing process, it is not possible to mass-produce 100% completely intact ampoules.

The present invention has been devised to obtain a completely intact ampoule by removing the foreign matter introduced into the ampoule during the manufacturing process of the ampoule. The method of manufacturing the ampoule and the manufacturing process thereof will be described below.

The material of the ampoule uses a long glass tube. When the part is heated while the glass tube is rotated and the heated portion is pulled in the longitudinal direction, the length increases and the diameter shrinks and narrows.

The ampoule is manufactured by cutting the glass tube thus deformed at a predetermined interval. In the preparation of the ampoule as described above, there is a manufacturing method by a vertical moving method of vertically moving the glass tube and supplying it vertically from the top and horizontally moving the glass tube horizontally.

The present invention can be applied to either the manufacturing method by the horizontal movement method of the glass tube and the manufacturing method by the vertical movement method, in the following description will be described by the method by the vertical movement method. For reference, the difference between the ampule manufactured by the horizontal moving method and the method manufactured by the vertical moving method may be described as follows.

The ampoule manufactured by the vertical movement method is contracted by applying heat to cut the deformed and undeformed parts so that the deflated part is the inlet of the ampoule, and the unretracted part is another ample lower (bottom). The molding process was carried out again to obtain an ampoule from a long glass tube.

In addition, the parts of the ampoules produced by the horizontal movement method are cut by cutting the center of the shrinkage-deformed portion and the center of the undeformed glass tube by applying heat to the lower portion of the ampoule. The bottom part) is molded again to obtain an ampoule.

As mentioned above, in the manufacture of the ampoule, a long glass tube is heated and a high hardness cutting edge such as a diamond disc or a diamond rotating at high speed is used as a means of cutting the glass tube deformed by pulling the heated portion. Fine glass powder generated during cutting is introduced into the ampoule.

Therefore, if fine glass powder flowing into the ampoule is not removed during the ampoule's washing process and foreign body inspection process, it will be undoubtedly introduced into the human body with the injection drug and adversely affect the human body.

The present invention has been made to solve the manufacturing defect that the fine glass powder may be introduced into the ampoule during the cutting process in the conventional ampoule, the present invention is to use a disc cutter or a diamond blade to rotate the high-speed cutting of the glass tube Instead, the glass tube is melted and cut by a flame to remove the source of glass powder.

Thus, the ampoules produced by the present invention can obtain 100% fully dust-free ampoules.

Before describing the present invention in detail, the manufacturing process of the conventional ampoule by the vertical transfer method will be described in detail for each process.

[First Conventional Process]: (See FIG. 1)

The present step is sufficiently heated by the burner 2 while rotating the glass tube 1 vertically supplied by the heating step.

[Conventional Second Step]: (See Fig. 2)

This step pulls the glass tube 1 sufficiently heated by the stretching process in the longitudinal direction to increase the heated portion.

[Conventional Third Step]: (See Fig. 3)

In this process, the head and neck of the ampoule are formed, and the neck (3 ') and the head (3 ") of the ampoule 3 are processed using the burner (2') and the assisting tool (4). The neck (3 ') is the cut part of the ampoule.

[Fourth Step]: (See Fig. 4)

In this step, the separation process is performed in the second step, which is a shrinkage step, and the boundary between the deformed part and the undeformed glass tube is heated with a burner and separated up and down. At this time, the lower part of the ampoule 3 is sealed at the inlet melted.

[Conventional Fifth Step]: (See Fig. 5)

In this step, the fixing of the ampoule 3 separated by the transfer process is released and transferred.

[The conventional sixth process]: (refer FIG. 6)

In this step, the cutting groove 7 is drawn by the disc carter 6 or the cutting edge which rotates the ampoule 3 to the roller 5 at a high speed while cutting the outer periphery of the end of the ampoule.

[Conventional Seventh Step]: (See Fig. 7)

In this step, the cutting groove 7 formed in the upper end of the ampoule is heated by the burner 2 ″ in the heating step to be vulnerable.

[Conventional 8th process]: (refer FIG. 8)

In this process, the cutting groove 7 is cut by giving an impact by vibrating the ampoule in the cutting process or hitting the upper end of the ampoule.

[Conventional 9th process]: (refer FIG. 9)

This process melts the inlet edge of the ampoule 3 cut by the end heating process with a burner 2 "to remove the sharp part.

[Conventional Tenth Step]: (See Fig. 10)

This process is a pigment coating process (also known as color braking) to coat the strip (8) with a pigment on the neck (3 ') of the ampoule as a means for easily cutting the neck (3) portion of the ampoule in the future.

[The conventional eleventh process]

This process is a printing process which screen-prints a dose, an injection name, a manufacturer, etc. on the surface of the ampoule 3.

[12th conventional process]

This process heats the ampoule 3 in the heating furnace 9 for a predetermined time by a heat treatment process.

In this step, the pigment applied to the neck of the ampoule is melted into the glass in the tenth step, and the printing ink printed in the eleventh step is heated and dried to be completely deposited on the glass, and at the same time, it is suddenly stretched and stretched in the second step. The heat is applied to the parts again to impart durability and robustness.

[Step 13]

This process is to inspect and remove the defective ampoule. Through the above process, the preparation of the ampoule is completed. Ampoules are containers for injecting medicine to treat diseases.

However, as shown in the sixth, seventh, and eighth steps of the conventional ampoule, a cutting groove 7 is formed at the end of the ampoule by a disk cart 6 which rotates at high speed by means of opening the inlet of the ampoule. Heat is applied to make it vulnerable and then vibrate or hit the top to cut the top of the ampoule.

This method of cutting the top of the ampoule is one of the methods to minimize the generation of glass powder during cutting. However, even in this case, generation of fine glass powder is inevitable, and the glass sufficiently has a possibility of being introduced into the ampoule.

If the fine glass powder generated during the inlet cutting of the ampoule enters the inside of the ampoule, the fine glass powder is not easily removed because it is in close contact with the inner wall of the ampoule due to the low heat received in the heat treatment process of the twelfth step.

Therefore, when the fine glass powder introduced in the sterilization and washing process performed immediately before the injection of the injection solution cannot be removed, it may be mixed with the injection solution and introduced into the human body.

In the present invention, glass powder is generated when the upper part of the ampoule is cut, thus eliminating the substance that can be introduced into the ampoule, thereby producing a fully dust-free ampoule as well as reducing the glass tube that is the material of the ampoule, thereby increasing production. As a result, the process of reinforcing the inlet of the ampoule allows for a more robust ampoule.

Looking at the ampoule manufacturing process according to the present invention as follows.

Since the ampoule manufactured by the present invention is the same as the fourth step in the first step of the conventional ampoule manufacturing step described above, the fourth step in the first step of the manufacturing step is omitted.

[Step 5]: (See Fig. 13)

This process is an end working process, in which the burner 11, 12 is heated in the glass tube 1 and the ampoule 3 separated up and down in the fourth process, and the upper glass tube 1 is melted and sealed, The ampoule 3 heats the sealing portion to melt the thickness thinly.

[Sixth Step]

This process also inserts the air nozzle 14 in the center of the upper glass tube 1 which was rounded (convexly) by the end processing process, and pushes the molten bottom by wind and pushes it in concave to cool the bottom part.

At the same time, the upper end of the lower ampoule 3 is heated and the thinner is melted by a burner 13 that emits a horizontal flame to open the inlet.

[7th process]

In this process, the air nozzle 15 is inserted into the upper end of the inlet of the ampoule 3 by the end forming process of the ampoule. The end of the ampoule 3 and the reinforced edge 3 '' are cold-formed and inserted into the ampoule 3 at the same time. Blow off any dirt or dust.

[Step 8]

In this step, the ampoules are transferred to the next step by releasing the fasteners 16 that hold the ampules 3 in the transfer step.

Hereinafter, the ampoule manufacturing process of the present invention performs a color brake liquid coating process, a printing process, a heat treatment process, and an inspection process of ampoule necks, which are less than or equal to the tenth process of the conventional ampoule manufacturing, to complete all manufacturing processes.

Looking at the operation and effects of the present invention as follows.

In the preparation of the ampoule from the glass tube which is upright and supplied from the top to the bottom, immediately after separating the upper glass tube and the lower ampoule with the flame of the burner, the lower ampoule is sealed in the inlet.

When the upper end of the sealed ampoule is continuously heated, the sealed portion melts and the thickness thereof becomes thin. At the same time, the melted portion is formed as a band to form an edge of the inlet of the ampoule.

The upper part of the thinned ampoule is then blown out with a burner (13) which blows out the flame horizontally, opening the ampoule's inlet and simultaneously placing the air nozzle (15) in the center of the ampoule's inlet and blowing air into the ampoule (3). At the time of receiving the heat, the inlet of the ampoule 3 in the molten state is cold formed and simultaneously removes dust and the like in the ampoule 3.

The air injected from the air nozzle 15 opens the inlet of the ampoule in the molten state to the outside and at the same time makes the inlet of the ampoule round.

As described above, the inlet of the wind-cooled ampoule has a strip because the upper glass is melted and flowed down as described above, so that the strip reinforces the inlet, which is the weakest part of the ampoule, to provide a strong ampoule.

In addition, since the ampoule manufactured by the present invention does not have a portion to be cut as in the conventional method, the amount of production is increased according to the reduction of the material, and the manufacturing process is simplified, which has the advantage of reducing the production line.

In the conventional ampoule, not only the foreign material such as glass powder is introduced into the ampoule in the manufacturing process, but also the inlet of the ampoule is the most vulnerable part, and a large amount is damaged in the transportation or other manufacturing process.

That is, the ampoule is cleaned just before the injection of the injection into the ampoule, and when the washing nozzle touches the inlet of the ampoule, the ampoule is broken.

In addition, in the conventional ampoule, the inlet of the ampoule was sometimes broken because the tongs were turned while holding the inlet of the ampoule and sealing the inlet of the ampoule.

However, in the present invention, the inlet of the ampoule is reinforced to completely remove the damage of the ampoule during the cleaning or sealing process.

In this way, the present invention can increase the production volume by reducing the material, the process is simple, mass production is possible, by adopting a method of cutting by the flame completely eliminates the inflow of glass powder generated during cutting and at the same time It is a very useful invention that can be reinforced to obtain a strong ampoule.

Claims (1)

In continuously manufacturing the ampule 3 from the glass tube 1, when separating the ampoule 3 from the upper glass tube 1, the upper end is rounded and sealed, and then it is heated and melted again by the burner 12 to round Forming the upper end very thin and then blowing it with a burner (13) to open the inlet, the method of manufacturing an ampule, characterized in that the molten is composed of a reinforcing edge (3 '") of the inlet periphery.