KR940002226A - Oxidation Method of Pyridine Derivatives - Google Patents

Oxidation Method of Pyridine Derivatives Download PDF

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Publication number
KR940002226A
KR940002226A KR1019920013166A KR920013166A KR940002226A KR 940002226 A KR940002226 A KR 940002226A KR 1019920013166 A KR1019920013166 A KR 1019920013166A KR 920013166 A KR920013166 A KR 920013166A KR 940002226 A KR940002226 A KR 940002226A
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KR
South Korea
Prior art keywords
pyridine
buffer solution
barium sulfate
formula
hydrogen peroxide
Prior art date
Application number
KR1019920013166A
Other languages
Korean (ko)
Inventor
박무신
강석민
Original Assignee
하기주
주식회사 코오롱
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by 하기주, 주식회사 코오롱 filed Critical 하기주
Priority to KR1019920013166A priority Critical patent/KR940002226A/en
Publication of KR940002226A publication Critical patent/KR940002226A/en

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  • Pyridine Compounds (AREA)

Abstract

본 발명은 피리딘 유도체 산화 방법에 관한 것이다.The present invention relates to a method of oxidizing pyridine derivatives.

일반식(Ⅰ)의 피리딘 화합물을 초산 용매하에서 과산화 수소로 산화시켜 일반식(Ⅱ)의 피리딘-N-옥사이드 화합물을 제조할 때, 잔류하는 과산화수소의 파괴방법으로 황산-황산바륨 완충용액과 이소프로필 알콜을 첨가하므로서, 폭발위험성이 제거되고 고순도 및 고수유로 제조할 수 있는 방법으로서, 반응조작이 간편한 장점이 있다.When the pyridine compound of formula (I) is oxidized with hydrogen peroxide in a solvent of acetic acid to prepare a pyridine-N-oxide compound of formula (II), the method of destroying the residual hydrogen peroxide and the barium sulfate buffer solution and isopropyl By adding alcohol, the explosion hazard is eliminated and can be manufactured with high purity and high lactation.

상기식중 R,R1은 H 또는 CH3이다.Wherein R, R 1 is H or CH 3 .

Description

피리딘 유도체의 산화방법Oxidation Method of Pyridine Derivatives

본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음Since this is an open matter, no full text was included.

Claims (2)

일반식(Ⅰ)의 피리딘 화합물을 초산 용매하에서 과산화 수소로 산화시킬때, 황산-황산바륨 완충용액과 이소프로필 알콜을 첨가함을 특징으로 하는 일반식(Ⅱ)의 피리딘-N-옥사이드 화합물의 제조 방법.Preparation of the pyridine-N-oxide compound of general formula (II) characterized by adding a sulfuric acid-barium sulfate buffer solution and isopropyl alcohol when the pyridine compound of general formula (I) is oxidized with hydrogen peroxide in a solvent of acetic acid. Way. 상기식중 R,R1은 H 또는 CH3이다.Wherein R, R 1 is H or CH 3 . 제1항에 있어서, 황산-황산 바륨 완충용액이 3% 황산 바륨의 5N 황산 완충용액 임을 특징으로 하는 일반식(Ⅱ)의 피리딘-N-옥사이드 화합물의 제조방법.The method for preparing a pyridine-N-oxide compound of formula (II) according to claim 1, wherein the sulfuric acid-barium sulfate buffer solution is a 5N sulfuric acid buffer solution of 3% barium sulfate. ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.※ Note: The disclosure is based on the initial application.
KR1019920013166A 1992-07-23 1992-07-23 Oxidation Method of Pyridine Derivatives KR940002226A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
KR1019920013166A KR940002226A (en) 1992-07-23 1992-07-23 Oxidation Method of Pyridine Derivatives

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
KR1019920013166A KR940002226A (en) 1992-07-23 1992-07-23 Oxidation Method of Pyridine Derivatives

Publications (1)

Publication Number Publication Date
KR940002226A true KR940002226A (en) 1994-02-16

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KR1019920013166A KR940002226A (en) 1992-07-23 1992-07-23 Oxidation Method of Pyridine Derivatives

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100412412B1 (en) * 2001-09-18 2003-12-31 위니아만도 주식회사 Structure for supply drawer type storeroom of Kim-Chi storage with cool air

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100412412B1 (en) * 2001-09-18 2003-12-31 위니아만도 주식회사 Structure for supply drawer type storeroom of Kim-Chi storage with cool air

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