KR930703328A - Insecticide compound - Google Patents

Insecticide compound

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Publication number
KR930703328A
KR930703328A KR1019930701820A KR930701820A KR930703328A KR 930703328 A KR930703328 A KR 930703328A KR 1019930701820 A KR1019930701820 A KR 1019930701820A KR 930701820 A KR930701820 A KR 930701820A KR 930703328 A KR930703328 A KR 930703328A
Authority
KR
South Korea
Prior art keywords
compound
methyl
hydrogen
formula
group
Prior art date
Application number
KR1019930701820A
Other languages
Korean (ko)
Inventor
존 패트릭 라킨
알렉산더 데이비드 프렌켈
Original Assignee
쟝 끌로드 비에이으포스
로우셀-우크라프
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 쟝 끌로드 비에이으포스, 로우셀-우크라프 filed Critical 쟝 끌로드 비에이으포스
Publication of KR930703328A publication Critical patent/KR930703328A/en

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D495/00Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/08Bridged systems
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/02Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms
    • A01N43/24Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms with two or more hetero atoms
    • A01N43/32Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms with two or more hetero atoms six-membered rings
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/90Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having two or more relevant hetero rings, condensed among themselves or with a common carbocyclic ring system
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D339/00Heterocyclic compounds containing rings having two sulfur atoms as the only ring hetero atoms
    • C07D339/08Six-membered rings

Abstract

본 발명은 하기 일반식(I)의 화합물에 관한 것이다.The present invention relates to compounds of the following general formula (I).

상기 식중, n및 n'는 각각 동일 또는 상이한 것으로서 각각 0,1 또는 2이고, R은 수소 또는 메틸이고, R1은 메틸, 에틸 또는 시클로프로필이며, R2및 R3은 동일 또는 상이한 것으로서 각각 수소 또는 메틸이고, Ra는 수소 또는 메틸이고, Rb는 시아노이거나, 또는 Ra및 Rb는 결합하여 m이 0,1 또는 2인 CH2S(O)m기를 형성한다. 또한 일반식(I)의 화합물의 제조 방법, 본 화합물을 함유하는 살충제 제제, 해충 억제제로서 용도로 기술되어 있다.Wherein n and n 'are the same or different, respectively, 0, 1 or 2, R is hydrogen or methyl, R 1 is methyl, ethyl or cyclopropyl, and R 2 and R 3 are the same or different, respectively Hydrogen or methyl, R a is hydrogen or methyl, R b is cyano, or R a and R b combine to form a CH 2 S (O) m group where m is 0,1 or 2. It is also described for use as a process for the preparation of the compound of formula (I), as a pesticide preparation containing the compound, and as a pest inhibitor.

Description

살충 화합물Insecticide compound

본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음Since this is an open matter, no full text was included.

Claims (18)

일반식(I)의 화합물:Compound of general formula (I): 상기 식중, n및 n'는 각각 0,1 또는 2이고, R은 수소 또는 메틸이고, R1은 메틸, 에틸 또는 시클로프로필이고, R2및 R3은 동일 또는 상이한 것으로서 각각 수소 또는 메틸이고, Ra는 수소 또는 메틸이고, Rb는 시아노이거나, 또는 Ra및 Rb는 결합하여 m이 0,1 또는 2인 CH2S(O)m기를 형성한다.Wherein n and n 'are each 0, 1 or 2, R is hydrogen or methyl, R 1 is methyl, ethyl or cyclopropyl, R 2 and R 3 are the same or different and are each hydrogen or methyl, R a is hydrogen or methyl and R b is cyano, or R a and R b combine to form a CH 2 S (O) m group where m is 0,1 or 2. 제1항에 있어서, R이 수소인 화합물.The compound of claim 1, wherein R is hydrogen. 제1항 또는 제2항에 있어서, Ra및 Rb가 결합하여 CH2S(O)m기를 형성하며, R1은 에틸인 화합물.3. The compound of claim 1, wherein R a and R b combine to form a CH 2 S (O) m group, wherein R 1 is ethyl. 제3항에 있어서, R2및 R3가 수소인 화합물.The compound of claim 3, wherein R 2 and R 3 are hydrogen. 제3항에 또는 제4항에 있어서, m,n 및 n'가 0인 화합물.5. The compound of claim 3 or 4, wherein m, n and n ′ are 0. 6. 제1항 또는 제2항에 있어서, Ra가 수소 또는 메틸이고, Rb가 시아노인 화합물.The compound of claim 1 or 2, wherein R a is hydrogen or methyl and R b is cyano. 제6항에 있어서, R1,R2및 R3가 모두 메틸인 화합물.The compound of claim 6, wherein R 1 , R 2 and R 3 are all methyl. 제1항에 있어서, 1-(3,3-디메틸부틸)-4-n-프로필-2,6,7-트리티아비시클로[2.2.2]옥탄 , 1-(3,3-디메틸부틸)-4-n-프로필-2,6,7-트리티아비시클로[2.2.2]옥탄-2-옥사이드, 5-t-부틴-2-시아노-2-(3,3-디메틸부틸)-1,3-디티안, 1-(3,3-디메틸부틸)-4-에틸-2,6,7-트리티아비시클로[2.2.2]옥탄으로부터 선택된 화합물.The compound of claim 1, wherein 1- (3,3-dimethylbutyl) -4-n-propyl-2,6,7-trithiabicyclo [2.2.2] octane, 1- (3,3-dimethylbutyl) -4-n-propyl-2,6,7-trithiabicyclo [2.2.2] octane-2-oxide, 5-t-butyn-2-cyano-2- (3,3-dimethylbutyl)- 1,3-dithiane, 1- (3,3-dimethylbutyl) -4-ethyl-2,6,7-trithiabicyclo [2.2.2] octane. (i)하기 일반식(IV)화합물의 음이온을 알킬화제가 반응시키거나, 또는 (ii) Ra및 Rb가 결합하여 CH2S(O)m기를 형성하는 경우, 하기 일반식(V)의 화합물을 a)루이스 산의 존재하에 tBuCH2CH2X화합물 또는 b)적절한 산 존재하에 tBuCH2CH2CN화합물과 반응시키는 것을 특징으로 하는 하기 일반식(I)의 화합물의 제조방법.(i) when an alkylating agent reacts the anion of the compound of formula (IV), or (ii) R a and R b combine to form a CH 2 S (O) m group, A process for preparing a compound of formula (I) wherein the compound is reacted with a) a tBuCH 2 CH 2 X compound in the presence of a Lewis acid or b) a tBuCH 2 CH 2 CN compound in the presence of a suitable acid. 상기 식 중, n 및 n'는 각각 0,1 또는 2이고, R은 수소 또는 메틸이고, R1은 메틸, 에틸 또는 시클로프로필이고 R2및 R3은 동일 또는 상이한 것으로서 각각 수소 또는 메틸이고, Ra는 수소 또는 메틸이고, Rb는 시아노이거나 또는 Ra및 Rb는 결합하여 m이 0,1 또는 2인 CH2S(O)m기를 형성하며, X는 활성화 카르복실산기이다.Wherein n and n 'are each 0, 1 or 2, R is hydrogen or methyl, R 1 is methyl, ethyl or cyclopropyl and R 2 and R 3 are the same or different and are each hydrogen or methyl, R a is hydrogen or methyl, R b is cyano or R a and R b are joined to form a CH 2 S (O) m group where m is 0,1 or 2, and X is an activated carboxylic acid group. 제1항 내지 제8항중 어느 한 항에 정의된 일반식(I)의 화합물을 1종상의 담체 또는 희석제와 함께 함유하는 살충제 제제.An insecticide formulation containing a compound of formula (I) as defined in any one of claims 1 to 8 together with one or more carriers or diluents. 제10항에 있어서, 부가적으로 공효약 또는 효과 강화제를 함유하는 살충제 제제.The pesticide formulation according to claim 10, which additionally contains a co-drug or an effect enhancer. 제10항 또는 제11항에 있어서, 부가적으로 1종 이상의 살충 활성 성분, 유인제, 방충제, 살균제, 실진균제 및(또는) 구충제를 함유하는 살충제 제제.The pesticide preparation according to claim 10 or 11, which additionally contains at least one pesticidal active ingredient, attractant, insect repellent, fungicide, fungicide and / or insect repellent. 유효량의 제1항 내지 제8항중 어느 한 항에 따른 화합물을 절지동물, 기생충 또는 연체동물, 또는 그들의 환경에 투여하는 것을 특징으로 하는 절지동물, 기생충 또는 연체동물 해충의 억제방법.A method of inhibiting arthropods, parasites or molluscs pests, comprising administering an effective amount of a compound according to any one of claims 1 to 8 to arthropods, parasites or mollusks or their environment. 유효량의 제1항 내지 제8항중 어느 한항에 정의된 일반식(I)의 화합물을 식물에 투여하는 것을 특징으로 하는 식물의 해충 만연 억제 방법.An effective amount of a compound of formula (I) as defined in any one of claims 1 to 8, which is administered to a plant. 유효량의 제1항 내지 제8항 중에 어느 한 항에 정의된 일반식(I)의 화합물을 저장 제품에 투여하는 것을 특징으로 하는 저장 제품의 해충 만연 억제 방법.An effective amount of a compound of formula (I) as defined in any one of claims 1 to 8 is administered to a storage product. 유효량의 제1항 내지 제8항중 어느 한 항에 정의된 일반식(I)의 화합물을 동물에 투여하는 것을 특징으로 하는 저장 제품의 해충 만연 억제 방법.A method of inhibiting pest spread of a storage product, characterized by administering to the animal an effective amount of a compound of formula (I) as defined in any one of claims 1 to 8. 동물의 해충 만연 억제에 사용되는 제1항 내지 제8항중 어느 한항에 정의된 일반식(I)의 화합물.A compound of formula (I) as defined in any one of claims 1 to 8 for use in the inhibition of pest spread in animals. 제17항에 있어서, 상기 동물이 사람인 용도.18. The use of claim 17, wherein said animal is a human. ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.※ Note: The disclosure is based on the initial application.
KR1019930701820A 1990-12-17 1991-12-16 Insecticide compound KR930703328A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB90272469 1990-12-17
GB909027246A GB9027246D0 (en) 1990-12-17 1990-12-17 Pesticidal compounds
PCT/GB1991/002239 WO1992011253A1 (en) 1990-12-17 1991-12-16 Pesticidal compounds

Publications (1)

Publication Number Publication Date
KR930703328A true KR930703328A (en) 1993-11-29

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ID=10687078

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019930701820A KR930703328A (en) 1990-12-17 1991-12-16 Insecticide compound

Country Status (12)

Country Link
EP (1) EP0563104A1 (en)
JP (1) JPH06504046A (en)
KR (1) KR930703328A (en)
AU (1) AU663691B2 (en)
BR (1) BR9107168A (en)
CA (1) CA2098390A1 (en)
CZ (1) CZ114293A3 (en)
FI (1) FI932766A (en)
GB (1) GB9027246D0 (en)
HU (1) HUT68462A (en)
NO (1) NO932219L (en)
WO (1) WO1992011253A1 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9427483B2 (en) 2014-04-04 2016-08-30 The Curators Of The University Of Missouri Radioisotope trithiol complexes
TW202330510A (en) * 2021-10-06 2023-08-01 日商參天製藥股份有限公司 Sulfur-containing compound useful for treating or preventing presbyopia or like

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3133884A1 (en) * 1981-08-27 1983-03-10 Bayer Ag, 5090 Leverkusen 2,5-DISUBSTITUTED-1,3-DITHIANE, METHOD FOR THE PRODUCTION AND USE THEREOF
EG19064A (en) * 1987-06-05 1994-07-30 Wellcome Found Novel heterocyclic pesticidal compounds
DK167188B1 (en) * 1987-07-22 1993-09-13 Wellcome Found SUBSTITUTED HETEROBICYCLOOCTANES, PESTICIDE PREPARATIONS CONTAINING SUCH COMPOUNDS, NON-THERAPEUTIC PROCEDURES TO COMBAT ARTHROPODS OR WARM OR ATTEMPTABLE HARMFUL OR ALARMABLE ALARM.
GB8827885D0 (en) * 1988-11-30 1989-01-05 Wellcome Found Novel heterocyclic pesticidal compounds
US5026874A (en) * 1989-01-24 1991-06-25 Wellcome Foundation Limited Pesticidal compounds

Also Published As

Publication number Publication date
WO1992011253A1 (en) 1992-07-09
BR9107168A (en) 1993-11-16
FI932766A0 (en) 1993-06-16
HU9301757D0 (en) 1993-09-28
EP0563104A1 (en) 1993-10-06
FI932766A (en) 1993-06-16
NO932219D0 (en) 1993-06-16
CA2098390A1 (en) 1992-06-18
HUT68462A (en) 1995-06-28
GB9027246D0 (en) 1991-02-06
AU9054591A (en) 1992-07-22
CZ114293A3 (en) 1994-02-16
NO932219L (en) 1993-06-16
JPH06504046A (en) 1994-05-12
AU663691B2 (en) 1995-10-19

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