KR930702508A - T 전구세포계의 배양방법 - Google Patents
T 전구세포계의 배양방법Info
- Publication number
- KR930702508A KR930702508A KR1019930700661A KR930700661A KR930702508A KR 930702508 A KR930702508 A KR 930702508A KR 1019930700661 A KR1019930700661 A KR 1019930700661A KR 930700661 A KR930700661 A KR 930700661A KR 930702508 A KR930702508 A KR 930702508A
- Authority
- KR
- South Korea
- Prior art keywords
- culture method
- cell culture
- progenitor cell
- nutrient medium
- oxygen dissolved
- Prior art date
Links
- 238000004113 cell culture Methods 0.000 title 1
- 210000000130 stem cell Anatomy 0.000 title 1
- 210000004027 cell Anatomy 0.000 abstract 3
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 2
- 238000012258 culturing Methods 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 235000015097 nutrients Nutrition 0.000 abstract 2
- 229910052760 oxygen Inorganic materials 0.000 abstract 2
- 239000001301 oxygen Substances 0.000 abstract 2
- 239000002243 precursor Substances 0.000 abstract 2
- 210000001744 T-lymphocyte Anatomy 0.000 abstract 1
- 239000000427 antigen Substances 0.000 abstract 1
- 102000036639 antigens Human genes 0.000 abstract 1
- 108091007433 antigens Proteins 0.000 abstract 1
- 238000012136 culture method Methods 0.000 abstract 1
- 230000004069 differentiation Effects 0.000 abstract 1
- 238000007429 general method Methods 0.000 abstract 1
- 238000004062 sedimentation Methods 0.000 abstract 1
- 239000000725 suspension Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0634—Cells from the blood or the immune system
- C12N5/0636—T lymphocytes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/515—Animal cells
- A61K2039/5158—Antigen-pulsed cells, e.g. T-cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/02—Atmosphere, e.g. low oxygen conditions
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/20—Cytokines; Chemokines
- C12N2501/23—Interleukins [IL]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/50—Cell markers; Cell surface determinants
- C12N2501/59—Lectins
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2502/00—Coculture with; Conditioned medium produced by
- C12N2502/11—Coculture with; Conditioned medium produced by blood or immune system cells
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Biotechnology (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
- Genetics & Genomics (AREA)
- Chemical & Material Sciences (AREA)
- Zoology (AREA)
- Hematology (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Cell Biology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP25828391 | 1991-07-04 | ||
| JP91-258283 | 1991-07-04 | ||
| PCT/JP1992/000829 WO1993001277A1 (fr) | 1991-07-04 | 1992-07-01 | Procede de culture d'une lignee de cellules precurseurs t |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| KR930702508A true KR930702508A (ko) | 1993-09-09 |
| KR0152100B1 KR0152100B1 (ko) | 1998-10-01 |
Family
ID=17318102
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1019930700661A KR0152100B1 (ko) | 1991-07-04 | 1992-07-01 | 분화항원 표현형상 또는 기능상 분화, 성숙한 t세포를 제조하는 방법 |
Country Status (7)
| Country | Link |
|---|---|
| US (2) | US5476780A (ko) |
| EP (1) | EP0552372B1 (ko) |
| KR (1) | KR0152100B1 (ko) |
| AT (1) | ATE180830T1 (ko) |
| CA (1) | CA2090677C (ko) |
| DE (1) | DE69229333D1 (ko) |
| WO (1) | WO1993001277A1 (ko) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2206449A1 (en) * | 1994-12-01 | 1996-06-06 | Beth Israel Deaconess Medical Center, Inc. | In vitro t-lymphopoiesis system |
| JP3818324B2 (ja) * | 1996-03-26 | 2006-09-06 | 三菱瓦斯化学株式会社 | ガス濃度調節剤及び低酸素濃度環境の調節方法 |
| US7718644B2 (en) | 2004-01-22 | 2010-05-18 | The Trustees Of Columbia University In The City Of New York | Anti-arrhythmic and heart failure drugs that target the leak in the ryanodine receptor (RyR2) and uses thereof |
| US8022058B2 (en) | 2000-05-10 | 2011-09-20 | The Trustees Of Columbia University In The City Of New York | Agents for preventing and treating disorders involving modulation of the RyR receptors |
| US7393652B2 (en) | 2000-05-10 | 2008-07-01 | The Trustees Of Columbia University In The City Of New York | Methods for identifying a chemical compound that directly enhances binding of FKBP12.6 to PKA-phosphorylated type 2 ryanodine receptor (RyR2) |
| US7879840B2 (en) | 2005-08-25 | 2011-02-01 | The Trustees Of Columbia University In The City Of New York | Agents for preventing and treating disorders involving modulation of the RyR receptors |
| US7544678B2 (en) | 2002-11-05 | 2009-06-09 | The Trustees Of Columbia University In The City Of New York | Anti-arrythmic and heart failure drugs that target the leak in the ryanodine receptor (RyR2) |
| WO2004080283A2 (en) | 2003-03-07 | 2004-09-23 | The Trustees Of Columbia University, In The City Of New York | Type 1 ryanodine receptor-based methods |
| US8710045B2 (en) | 2004-01-22 | 2014-04-29 | The Trustees Of Columbia University In The City Of New York | Agents for preventing and treating disorders involving modulation of the ryanodine receptors |
| US7704990B2 (en) | 2005-08-25 | 2010-04-27 | The Trustees Of Columbia University In The City Of New York | Agents for preventing and treating disorders involving modulation of the RyR receptors |
| WO2019174842A1 (en) | 2018-03-13 | 2019-09-19 | Oxacell Ag | Cell products with improved stability and uses thereof |
| US20210324331A1 (en) * | 2020-04-15 | 2021-10-21 | Amgen Inc. | Process for generating genetically engineered autologous t cells |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4284724A (en) * | 1977-08-25 | 1981-08-18 | Hideki Fukuda | Method of highly concentrated cultivation of yeasts |
| DE2940446C2 (de) * | 1979-10-05 | 1982-07-08 | B. Braun Melsungen Ag, 3508 Melsungen | Züchtung von tierischen Zellen in Suspensions- und Monolayerkulturen in Fermentationsgefäßen |
| US4448879A (en) * | 1981-03-26 | 1984-05-15 | Hooper Trading Company | High yield process for in vitro production of serum-free and mitogen-free interleukin-2 |
| JPS6192566A (ja) * | 1984-10-12 | 1986-05-10 | Wakunaga Seiyaku Kk | 抗体産生細胞の調製方法 |
| JPS61166393A (ja) * | 1985-01-14 | 1986-07-28 | Mitsubishi Chem Ind Ltd | Ｂリンパ球及び／又はｔリンパ球の培養法 |
| US4720462A (en) * | 1985-11-05 | 1988-01-19 | Robert Rosenson | Culture system for the culture of solid tissue masses and method of using the same |
| EP0302894B1 (en) * | 1986-04-28 | 1992-11-19 | Endotronics Inc. | Method of culturing leukocytes |
| EP0420876A1 (en) * | 1988-05-23 | 1991-04-10 | Massachusetts Institute Of Technology | Growth of animal cells at high oxygen concentration |
| JP2837856B2 (ja) * | 1988-11-11 | 1998-12-16 | イハラケミカル工業株式会社 | リンフォカイン活性化キラー細胞及びその製造法 |
| JP2870851B2 (ja) * | 1989-09-21 | 1999-03-17 | 富士レビオ株式会社 | ヒト成熟ｔ細胞株 |
| US5147784A (en) * | 1990-04-12 | 1992-09-15 | Systemix, Inc. | T-lymphocyte progenitor cell assay |
-
1992
- 1992-07-01 US US07/983,514 patent/US5476780A/en not_active Expired - Fee Related
- 1992-07-01 KR KR1019930700661A patent/KR0152100B1/ko not_active IP Right Cessation
- 1992-07-01 AT AT92914125T patent/ATE180830T1/de not_active IP Right Cessation
- 1992-07-01 CA CA002090677A patent/CA2090677C/en not_active Expired - Fee Related
- 1992-07-01 DE DE69229333T patent/DE69229333D1/de not_active Expired - Lifetime
- 1992-07-01 EP EP92914125A patent/EP0552372B1/en not_active Expired - Lifetime
- 1992-07-01 WO PCT/JP1992/000829 patent/WO1993001277A1/ja active IP Right Grant
-
1995
- 1995-09-11 US US08/526,084 patent/US5792655A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| ATE180830T1 (de) | 1999-06-15 |
| EP0552372B1 (en) | 1999-06-02 |
| KR0152100B1 (ko) | 1998-10-01 |
| EP0552372A1 (en) | 1993-07-28 |
| CA2090677C (en) | 1996-08-27 |
| US5792655A (en) | 1998-08-11 |
| CA2090677A1 (en) | 1993-01-05 |
| EP0552372A4 (en) | 1994-11-30 |
| DE69229333D1 (de) | 1999-07-08 |
| WO1993001277A1 (fr) | 1993-01-21 |
| US5476780A (en) | 1995-12-19 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| A201 | Request for examination | ||
| E902 | Notification of reason for refusal | ||
| E601 | Decision to refuse application | ||
| J2X1 | Appeal (before the patent court) |
Free format text: APPEAL AGAINST DECISION TO DECLINE REFUSAL |
|
| E701 | Decision to grant or registration of patent right | ||
| GRNT | Written decision to grant | ||
| LAPS | Lapse due to unpaid annual fee |