KR930000539A - 신규항 tcf-ii 모노클로날 항체 및 그것을 사용한 tcf-ii 측정방법 - Google Patents

신규항 tcf-ii 모노클로날 항체 및 그것을 사용한 tcf-ii 측정방법 Download PDF

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Publication number
KR930000539A
KR930000539A KR1019920009730A KR920009730A KR930000539A KR 930000539 A KR930000539 A KR 930000539A KR 1019920009730 A KR1019920009730 A KR 1019920009730A KR 920009730 A KR920009730 A KR 920009730A KR 930000539 A KR930000539 A KR 930000539A
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South Korea
Prior art keywords
val
ser
tcf
thr
leu
Prior art date
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KR1019920009730A
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English (en)
Inventor
노부유끼 시마
간지 히가시오
야스하루 이다가끼
후미꼬 오오가끼
Original Assignee
쇼노 가쯔야
유끼지루시유교 가부시끼가이샤
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Application filed by 쇼노 가쯔야, 유끼지루시유교 가부시끼가이샤 filed Critical 쇼노 가쯔야
Publication of KR930000539A publication Critical patent/KR930000539A/ko

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C07K14/4753—Hepatocyte growth factor; Scatter factor; Tumor cytotoxic factor II
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2/00—Peptides of undefined number of amino acids; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/22—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

내용 없음

Description

신규항 TCF-Ⅱ 모노클로날 항체 및 그것을 사용한 TCF-Ⅱ의 측정방법
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음
제1도는 모노클로날 항체의 조합에 의하여 얻어진 TCF-Ⅱ 측정표준곡선을 표시한다.

Claims (3)

  1. 사람 항종양성 단백질 TCF-Ⅱ에 대하여 특이적 친화성을 나타내며, 분자량 약 150000, 서브클라스 IgG1인 모노클로날항체.
  2. 모노클로날 항체의 L쇄의 N말단이 하기 아미노산배열(1)∼(3)의 어느 것으로 특정되는 청구항 1기재의 모노클로날 항체.
    (1) Asp-Val-Val-Leu-Thr-Gln-Ser-Pro-Ala-Thr-Leu-Ser-Val-Thr-Pro-Gly-
    1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16
    Asp-Ser-Val
    17 18 19
    (2) Asp-Sel-Val-Leu-Thr-Gln-Ser-Pro-Ala-Ser-Leu-Ala-Val-Ser-Leu-Gly-
    1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16
    Gln-Arg-Ala-Thr-Ile-Ser
    17 18 19 20 21 22
    (3) Asp-Ile-Val-Leu-Thr-Gln-Ser-Pro-Val-Thr-Leu-Ser-Val-Thr-Pro-Gly-
    1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16
    Gly-Ser-Val]
    17 18 19
  3. 사람 항종양성 단백질 TCF-Ⅱ를 청구항 2에 기재의 모노클로날 항체를 써서 측정하는 것을 특징으로 하는 TCF-Ⅱ의 측정방법.
    ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
KR1019920009730A 1991-06-21 1992-06-05 신규항 tcf-ii 모노클로날 항체 및 그것을 사용한 tcf-ii 측정방법 KR930000539A (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP177236 1991-06-21
JP3177236A JPH0597A (ja) 1991-06-21 1991-06-21 新規抗ｔｃｆ−ｉｉモノクローナル抗体及びそれを用いるｔｃｆ−ｉｉの測定方法

Publications (1)

Publication Number Publication Date
KR930000539A true KR930000539A (ko) 1993-01-15

Family

ID=16027530

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019920009730A KR930000539A (ko) 1991-06-21 1992-06-05 신규항 tcf-ii 모노클로날 항체 및 그것을 사용한 tcf-ii 측정방법

Country Status (4)

Country Link
EP (1) EP0519728A3 (ko)
JP (1) JPH0597A (ko)
KR (1) KR930000539A (ko)
CA (1) CA2071622A1 (ko)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU674871B2 (en) * 1992-07-16 1997-01-16 Atlas Pharmaceuticals Inc. Blood coagulation normalizer containing TCF-II as active ingredient
JP3402476B2 (ja) * 1992-08-24 2003-05-06 生化学工業株式会社 リポ多糖結合性タンパク質及びその製造法
US5707622A (en) * 1994-03-03 1998-01-13 Genentech, Inc. Methods for treating ulcerative colitis
US5874080A (en) * 1994-03-03 1999-02-23 Genentech, Inc. Anti-IL-8 monoclonal antibodies for treatment of asthma
JPH07258298A (ja) * 1994-03-18 1995-10-09 Snow Brand Milk Prod Co Ltd モノクローナル抗体
JP4006058B2 (ja) 1997-03-11 2007-11-14 第一三共株式会社 多臓器不全予防及び／又は治療剤
CA2253629A1 (en) 1997-03-14 1998-09-24 Snow Brand Milk Products Co., Ltd. Agent for preventing and/or treating cachexia
CN113049812B (zh) * 2021-03-26 2024-03-19 信达安检测技术(天津)有限公司 一种检测克百威的elisa方法及其试剂盒

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6427491A (en) * 1987-07-14 1989-01-30 Yasushi Daikuhara Monoclonal antibody
NZ232813A (en) * 1989-03-10 1992-08-26 Snow Brand Milk Products Co Ltd Human fibroblast glycoprotein, cell differentiation, blood vessel endothelial cell growth factor, cellular immunology inforcing factor of 78 or 74 thousand daltons plus or minus two thousand daltons

Also Published As

Publication number Publication date
EP0519728A3 (en) 1993-08-18
EP0519728A2 (en) 1992-12-23
CA2071622A1 (en) 1992-12-22
JPH0597A (ja) 1993-01-08

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