KR920002632A - 면역학적 캐리어 및 강화 특성을 지닌 나이세리아 메닌자이티디스 외막의 클래스 ⅱ 단백질 및 이를 함유하는 백신 - Google Patents
면역학적 캐리어 및 강화 특성을 지닌 나이세리아 메닌자이티디스 외막의 클래스 ⅱ 단백질 및 이를 함유하는 백신 Download PDFInfo
- Publication number
- KR920002632A KR920002632A KR1019910012309A KR910012309A KR920002632A KR 920002632 A KR920002632 A KR 920002632A KR 1019910012309 A KR1019910012309 A KR 1019910012309A KR 910012309 A KR910012309 A KR 910012309A KR 920002632 A KR920002632 A KR 920002632A
- Authority
- KR
- South Korea
- Prior art keywords
- protein
- class
- outer membrane
- neisseria meningitidis
- antigen
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/145—Orthomyxoviridae, e.g. influenza virus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55516—Proteins; Peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
- A61K2039/6031—Proteins
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Mycology (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Medicinal Chemistry (AREA)
- Microbiology (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Virology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Pulmonology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
Abstract
내용 없음
Description
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음
제1도는 PRP-OMPC로 면역화한 후 일정일에 취한 혈액 샘플에서 ELISA 및 RIA로 측정한, PRP-DT 및 MIEP, 또는 OMPC, 또는 IAA-OMPC로 개별적으로 프라이밍된 비장 세포를 수용하는 채택성 이전 수용자의 항체 반응도이다.
제2도는 시험관내에서 수행한 MIEP의 마이토젠(mitogen)활성에 대한 림프구 증식 검정도이다.
제3도는 PRP-MIEP 접합체의 마우스 및 새끼 붉은털 원숭이에서 수행한 면역원성 시험도이다.
Claims (4)
- 항원에 결합된 나이세리아 메닌자이티디스(Neisseria meningitidis) 혈청 그룹 B의 외막의 클래스 Ⅱ 단백질을 함유하고, 포유동물에서 상기 항원에 특이적인 항체의 형성을 유발하거나 강화시키는 포유동물용 백신.
- 제1항에 있어서, 항원이 세균, 바이러스, 포유동물세포, 진균, 리케챠, 알레르젠(allergen), 독(poisons) 또는 뱀독(venoms), 합성 펩타이드 및 폴리펩타이드 단편중에서 유도되는 방법.
- 제1항에 있어서, 나이세리아 메닌자이티디스 혈청 그룹 B의 외막의 클래스 Ⅱ 단백질이 재조합 숙주 세포에서 생성된 재조합 단백질인 백신.
- 헤모필루스 인플루엔제(Haemophilus influenzae) 혈청형 B 다당류와 나이세리아 메닌자이티디스 혈청 그룹 B의 클래스 Ⅱ 외막 단백질을 함유하는, 포유류의 면역화에 대한 유효량의 다당류/단백질 결합체 및 약제학적으로 허용되는 담체를 함유하는 조성물.※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US55532990A | 1990-07-19 | 1990-07-19 | |
US07/555,329 | 1990-07-19 | ||
US71527491A | 1991-06-19 | 1991-06-19 | |
US07/715,274 | 1991-06-19 |
Publications (1)
Publication Number | Publication Date |
---|---|
KR920002632A true KR920002632A (ko) | 1992-02-28 |
Family
ID=27070858
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
KR1019910012309A KR920002632A (ko) | 1990-07-19 | 1991-07-19 | 면역학적 캐리어 및 강화 특성을 지닌 나이세리아 메닌자이티디스 외막의 클래스 ⅱ 단백질 및 이를 함유하는 백신 |
Country Status (10)
Country | Link |
---|---|
JP (1) | JPH0655679B2 (ko) |
KR (1) | KR920002632A (ko) |
AU (1) | AU8113691A (ko) |
CA (1) | CA2050635A1 (ko) |
FI (1) | FI913475A (ko) |
IL (1) | IL98839A0 (ko) |
MX (1) | MX9100275A (ko) |
NO (1) | NO912823L (ko) |
NZ (1) | NZ238974A (ko) |
PT (1) | PT98382A (ko) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2004055239A1 (en) * | 2002-12-13 | 2004-07-01 | Korea Power Engineering Company, Inc. | Apparatus for cathodic protection in an environment in which thin film corrosive fluids are formed and method thereof |
CN100396819C (zh) * | 2002-12-13 | 2008-06-25 | 韩国电力技术株式会社 | 在形成薄膜腐蚀流体的环境中用于阴极保护的装置及方法 |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2371032A1 (en) * | 1999-04-30 | 2000-11-09 | Chiron Corporation | Neisseria genomic sequences and methods of their use |
-
1991
- 1991-07-15 IL IL98839A patent/IL98839A0/xx unknown
- 1991-07-15 CA CA002050635A patent/CA2050635A1/en not_active Abandoned
- 1991-07-15 NZ NZ238974A patent/NZ238974A/xx unknown
- 1991-07-18 MX MX919100275A patent/MX9100275A/es unknown
- 1991-07-18 AU AU81136/91A patent/AU8113691A/en not_active Abandoned
- 1991-07-18 PT PT98382A patent/PT98382A/pt not_active Application Discontinuation
- 1991-07-18 FI FI913475A patent/FI913475A/fi not_active Application Discontinuation
- 1991-07-18 NO NO91912823A patent/NO912823L/no unknown
- 1991-07-19 KR KR1019910012309A patent/KR920002632A/ko not_active Application Discontinuation
- 1991-07-19 JP JP3269966A patent/JPH0655679B2/ja not_active Expired - Lifetime
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2004055239A1 (en) * | 2002-12-13 | 2004-07-01 | Korea Power Engineering Company, Inc. | Apparatus for cathodic protection in an environment in which thin film corrosive fluids are formed and method thereof |
CN100396819C (zh) * | 2002-12-13 | 2008-06-25 | 韩国电力技术株式会社 | 在形成薄膜腐蚀流体的环境中用于阴极保护的装置及方法 |
Also Published As
Publication number | Publication date |
---|---|
IL98839A0 (en) | 1992-07-15 |
NO912823L (no) | 1992-01-20 |
CA2050635A1 (en) | 1992-01-20 |
JPH0616569A (ja) | 1994-01-25 |
FI913475A0 (fi) | 1991-07-18 |
PT98382A (pt) | 1992-05-29 |
MX9100275A (es) | 1992-02-28 |
FI913475A (fi) | 1992-01-20 |
JPH0655679B2 (ja) | 1994-07-27 |
NO912823D0 (no) | 1991-07-18 |
AU8113691A (en) | 1992-01-23 |
NZ238974A (en) | 1992-12-23 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
Dyrberg et al. | Peptides as antigens. Importance of orientation. | |
EP0232717B1 (en) | Antibody specific to low-molecular weight substance and method of producing the same by using colloidal metal particles as carrier | |
Leclerc et al. | A synthetic vaccine constructed by copolymerization of B and T cell determinants | |
CA2078694A1 (en) | Hepatitis b vaccine | |
PT649537E (pt) | Imunoanalises para anticorpos anti-vhc utilizando antigenios com epitopos conformacionais | |
HOSODA et al. | Effect of bridge heterologous combination on sensitivity in enzyme immunoassay for cortisol | |
KR940703851A (ko) | E형 간염 바이러스 펩타이드 항원 및 항체(hepatitis e virus peptide antigens and antibodies) | |
ES2176347T3 (es) | Modulacion de la respuesta inmune. | |
DE69019190D1 (de) | Pankreatische Isletzellen-Antigene, erhalten durch molekulare Klonierung. | |
Sakai et al. | Non-antigenic and low allergic gelatin produced by specific digestion with an enzyme-coupled matrix | |
JP2003525014A5 (ko) | ||
WO1999013907A3 (en) | Methods to improve immunogenicity of antigens and specificity of antibodies | |
Simons et al. | Mechanism of lymphocyte transformation induced by phytohaemagglutinin | |
KR920002632A (ko) | 면역학적 캐리어 및 강화 특성을 지닌 나이세리아 메닌자이티디스 외막의 클래스 ⅱ 단백질 및 이를 함유하는 백신 | |
KR880014376A (ko) | Hiv 특이 항원 영역의 모노클로날 항체 및 그 용법 | |
EP0582243A3 (de) | HCV Peptidantigene und Verfahren zur Bestimmung von HCV. | |
Norins et al. | Globulins on NZB mouse erythrocytes | |
KR920002631A (ko) | 면역학적 캐리어 및 강화 특성을 지닌 나이세리아 메닌자이티디스 외막의 클래스 ⅱ 단백질 | |
Park et al. | Targeted destruction of the polymerized human serum albumin binding site within the preS2 region of the HBV surface antigen while retaining full immunogenicity for this epitope | |
JP2553159B2 (ja) | 赤血球凝集アッセイ | |
CN107488232A (zh) | 一种His标签抗原的合成方法 | |
Roth et al. | Chronology of halothane-induced antigen expression in halothane-exposed rabbits. | |
Beuvery et al. | Meningococcal group C polysaccharide/tetanus toxoid conjugate as immunogen. | |
CN103163302B (zh) | 一种采用定向交叉偶联技术制备的短肽抗体试剂盒 | |
Aithal et al. | An alternate method utilizing small quantities of ligand for affinity purification of monospecific antibodies |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
WITN | Application deemed withdrawn, e.g. because no request for examination was filed or no examination fee was paid |