KR910003425B1 - Process for the preparing composition of treatment of dental disease - Google Patents
Process for the preparing composition of treatment of dental disease Download PDFInfo
- Publication number
- KR910003425B1 KR910003425B1 KR1019870003616A KR870003616A KR910003425B1 KR 910003425 B1 KR910003425 B1 KR 910003425B1 KR 1019870003616 A KR1019870003616 A KR 1019870003616A KR 870003616 A KR870003616 A KR 870003616A KR 910003425 B1 KR910003425 B1 KR 910003425B1
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- composition
- treatment
- salt
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- preparing composition
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
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- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Birds (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Botany (AREA)
- Biotechnology (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Inorganic Chemistry (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Cosmetics (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
Description
본 발명은 송진(松瞋)과 소금을 주재로 하는 구강질환 치료용 조성물 제조방법에 관한 것이다.The present invention relates to a method for producing a composition for treating oral diseases based on rosin and salt.
구강질환, 특히 충치의 예방과 치료에 여러 가지 수단과 벙법이 강구되어 왔으나 만족할 만한 효과를 기대할 수 없었고, 심한 경우에는 발치와 같은 물리적 방법까지 이용하게 되었다.Various methods and methods have been devised for the prevention and treatment of oral diseases, especially tooth decay, but no satisfactory effect can be expected. In severe cases, even physical methods such as extraction are used.
따라서, 저렴한 경비로 탁월한 효과를 가진 구강질환 예방 및 치료제의 개발이 절실하였다.Therefore, the development of oral disease prevention and treatment having excellent effects at a low cost is urgently needed.
본 발명의 목적은 값싼 송진과 소금을 주재로하여 충치예방과 치료에 신속하고 탁월한 효과를 가져오는 구강질환 치료용 조성물의 제조방법을 제공하는데 있다.It is an object of the present invention to provide a method for preparing a composition for treating oral diseases, which has a quick and excellent effect on the prevention and treatment of tooth decay based on cheap rosin and salt.
본 발명의 조성물은 소나무에서 체취한 송진을 소금과 대략 1 : 1 내지 5의 중량 비율로 혼합하여 용기에 넣은 후 잘 교반하면서 가열하여 미세한 분말로 파쇄함으로써 제조된다. 이러한 송진 및 소금 조성물을 직접 분말상태로 하거나 환제로 제형화하여 사용할 수도 있으나 여기에 적당량의 부형제, 즉 서방 부형제를 첨가하여 투여에 적합한 재형으로 조제한 후 사용할 수도 있다. 본 발명의 조성물을 환부에 직접 적용할 수도 있으나 구강질환의 예방을 위하여 양치질 할 때 치약에 적당량의 발명조성물 분말을 혼합하여 사용하여 사용할 수도 있다. 본 발명의 조성물은 특히 충치로 인한 통증의 완화에 신속하고도 현저한 효과를 나타낸다.The composition of the present invention is prepared by mixing the pine rosin taken from pine tree with salt at a weight ratio of about 1: 1 to 5, placing it in a container, and then heating it with good stirring to break it into fine powder. Such rosin and salt compositions may be directly powdered or formulated into pills, but may be used after the preparation of a suitable form for administration by adding an appropriate amount of excipient, that is, sustained-release excipient. The composition of the present invention may be applied directly to the affected part, but when brushing teeth for the prevention of oral diseases, an appropriate amount of the invention composition powder may be mixed and used in the toothpaste. The compositions of the present invention exhibit a rapid and significant effect, in particular, on the relief of pain due to tooth decay.
여기서 구강질환이라 함은 구강내의 여러 질환, 즉 충치, 치주염 그에 따른 치통 및 염증 등을 포함한다. 또한 치료 효과라 함은 3개월 이상 2년까지 질환의 재발 또는 통증이 없는 것을 뜻하며 예방효과라 함은 질환경험이 있었으나 더 이환되지 않는 경우 및 통상 이환되지 않는 상태의 유지 또는 그 지속을 뜻한다.Here, the term "oral disease" includes various diseases in the oral cavity, ie tooth decay, periodontitis, toothache and inflammation. In addition, the therapeutic effect means that there is no recurrence or pain of the disease for at least three months and two years, and the prophylactic effect means that the patient has experienced the disease but is not further diseased, and usually maintains or continues the diseased state.
본 발명을 더욱 자세히 설명하기 위해 다음 실시예를 예시한다.The following examples are illustrated to further illustrate the present invention.
[실시예 1]Example 1
소나무 성목에서 채취한 송진 1g을 굵은 소금 1 내지 5g과 섞어 제약용기에 넣고 잘 교반하면서 가열하여 용해 시킨다. 가열을 계속하면 변색이 일어나면서 건조한 상태가 되었을 때 방치하여 상온으로 냉각하고 미세한 분말 상태로 파쇄하여 본 발명의 산제조성물을 얻는다.1g of pine rosin from pine tree is mixed with 1-5g of coarse salt, put into a pharmaceutical container, and dissolved by heating while stirring well. If the heating is continued, the discoloration occurs and when it is dry, it is left to cool to room temperature and crushed into a fine powder to obtain the acid composition of the present invention.
[실시예 2]Example 2
상기 실시예 1에서 얻은 산제조성물에 약제학적으로 수용가능한 긍지의 부형제를 가하여 서방형의 과립제 또는 환제로 제형화 한다.Pharmaceutically acceptable excipients are added to the powder formulation obtained in Example 1 to form a sustained release granule or pill.
[실시예 3]Example 3
충치로 인한 치통을 호소하는 환자에게 실시예 1의 산제조성물을 적당량 탈지면을 이용하여 환부에 적용시킨 결과 5분내에 완벽한 진통효과를 얻을 수 있었다.In the patient complaining of toothache due to tooth decay, the powder composition of Example 1 was applied to the affected area using an appropriate amount of cotton wool, and a perfect analgesic effect was obtained within 5 minutes.
실시예 2에서 제조한 환제를 무균천에 싸서 통증이 심한 치아 부분에 적용시키자 5분내에 현저하게 통증이 완하되었으며 그후 5분후에 본 발명의 환제를 제거하였으나 6개월 이상 통증의 재발이 없었다. 이러한 임상효과는 매우 놀랄만한 것으로 평가되고 있으며 그후 충치의 진행이 정지되는 것으로 볼 때 충치를 유발하는 병균에 대하여 살균효과가 있는 것으로 확신할 수 있었다.When the pill prepared in Example 2 was wrapped in a sterile cloth and applied to the painful tooth part, the pain was remarkably relieved within 5 minutes, and after 5 minutes, the pill of the present invention was removed, but there was no recurrence of pain more than 6 months. This clinical effect is evaluated to be very surprising, and after that, the progression of the tooth decay can be convinced that the bactericidal effect against the disease causing the tooth decay.
본 발명 조성물의 투여량은 특별히 제한은 없으며 환부의 크기에 따라 광범위하게 적용할 수 있다. 즉 원료물질인 소금이나 송진의 인체에 대한 독성은 보고된바 없고 또한 본 발명 조성물을 복용하는 것이 아니므로 본 발명 조성물의 투여량이나 투여횟수는 진통효과를 얻는데 필요한 어떤 용량도 가능하다. 일반적으로 통증의 정도나 환부의 크기에 따라 본 발명의 조성물 약 100mg부터 10g 또는 그 이상도 사용할 수 있으며 완전히 진통효과가 나타날때까지 수차례 적용시킬 수도 있다.The dosage of the composition of the present invention is not particularly limited and may be widely applied depending on the size of the affected part. That is, the toxicity of the raw material salt or rosin to the human body has not been reported and since the dose of the present invention is not taken, the dosage or frequency of the present invention may be any dose necessary to obtain an analgesic effect. Generally, about 100 mg to 10 g or more of the composition of the present invention may be used, depending on the degree of pain or the size of the affected area, and may be applied several times until complete analgesic effect occurs.
Claims (1)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| KR1019870003616A KR910003425B1 (en) | 1987-04-15 | 1987-04-15 | Process for the preparing composition of treatment of dental disease |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| KR1019870003616A KR910003425B1 (en) | 1987-04-15 | 1987-04-15 | Process for the preparing composition of treatment of dental disease |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| KR880012206A KR880012206A (en) | 1988-11-26 |
| KR910003425B1 true KR910003425B1 (en) | 1991-05-31 |
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ID=19260761
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1019870003616A KR910003425B1 (en) | 1987-04-15 | 1987-04-15 | Process for the preparing composition of treatment of dental disease |
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| Country | Link |
|---|---|
| KR (1) | KR910003425B1 (en) |
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1987
- 1987-04-15 KR KR1019870003616A patent/KR910003425B1/en not_active IP Right Cessation
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| Publication number | Publication date |
|---|---|
| KR880012206A (en) | 1988-11-26 |
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