KR910001916B1 - Composition of shampoo - Google Patents

Abstract

A shampoo compsn. comprises 5-30 wt.% anionic surfactant, 5-30 wt.% non-ionic surfactant, 0.1-0.5 wt.% 1-hydroxy- 4-methyl-6-(2,4,4-trimethylpentyl)- 2(1H)-pyridone ethanol amine salt[piroctonelamine , 0.1-5.0 wt.% hydrochloric acid glycine-ampholytic surfactant, hair-conditioning agent, antiseptic, colour, perfume, pH-controlling agent, vicosity-controlling agent and water. The shampoo compsn. has a good dandruff removal effect and urtication prevention effect against hairs.

Description

[Name of invention]

Shampoo composition

Detailed description of the invention

The present invention provides a conventional shampoo composition by containing 1-hydroxy-4-methyl-6- (2, 4,4-trimethylpentyl) -2 (1H) -pyridone ethanolamine salt and glycine hydrochloride-based amphoteric surfactant. The present invention relates to a shampoo composition for treating and preventing dandruff and itching of the hair.

In general, dandruff refers to a large mass of dead cells in the scalp that come off as a stiff keratin, secreting sebum from the scalp, and sweating. In general, dandruff is accompanied by itching of the scalp at this time, if you scratch hard on the scalp, it hurts and eventually causes inflammation to cause eczema, hair loss.

The root cause of severe dandruff is known to be caused by the vigorous growth of microorganisms in the scalp, which may be thought of as a bactericidal preservative that can eliminate microorganisms in the scalp, but it is not the case. . The reason is that the microorganisms affect the metabolism of the scalp cells, but for some other reasons, such as endocrine hormone imbalances, nutrient metabolism imbalances, stress, fatigue, etc. Even before keratinization, it comes off and several scalp cells come together and eventually cause a lot of dandruff.

Therefore, in order to treat and prevent dandruff and itching should use anti-dandruff shampoo containing a component that has the effect of normalizing the abnormal metabolic activity of the scalp cells as well as the antiseptic antiseptic effect.

Among these ingredients, zinc pyrithione, the most commonly used anti-dandruff shampoo, is water insoluble and has a high specific gravity, which makes it very difficult to maintain a uniform dispersion in shampoo solution, and zinc pyrithione is highly irritating to eyes. Severe.

(See Gene A Hyde and Mark M. Auerbach, "Formulation Techniques for Zinc Pyrithione Antidandruff Shampoos", Cosmetics and Toiletries, 94, 57-, April 1979 Fred H. Snyder et al. "Safety Evaluation of Zinc 2-Pyridiethiol 1-Oxide in a shampoo Formulation ", Toxicology and Applied Pharmacology, 7, 425-437, 1965)

Recently developed as an alternative to solve the water insolubility and eye irritation defects of zinc pyrithione, 1-hydroxy-4-methyl-6- (2, 4, 4-trimethylpentyl) of the general formula (I) ) -2 (1H) -pyridone ethanolamine salt (common name: pyroxtoneolamine, referred to below as generic name) is easily dissolved by the surfactant component of the shampoo while being dissolved in a small amount in water, is not irritating to the eyes, and zinc It is known to have an anti-dandruff and itching effect equivalent to pyrithione.

(See Eberhard Futterer, "Evaluation of Efficacy of Antidandruff Agent", J. Soc. Cosmet. Chem. 32, 327-338, Nov. 1981 G. Dietrich et al., "A Practice-Oriented Test Method For Active Ingredients To Control Dandruff) ", Medical Cosmetology, 10, 34-45, 1980)

In order to show the anti-dandruff and itching effect of pyrotonolamine in shampoo, 0.5% -2.0% should be generally used.However, the anti-dandruff shampoo containing pyrotonolamine is more expensive than the general shampoo because pyrotonolamine is expensive. Since it is more than three times, the marketability as a product is not good. In recent years, there is a movement in Europe to regulate the maximum amount of pyrotonolamine to 0.5% due to the stability of the human body.

(Note: Cosmetics and Toiletries, 102, 6, Dec. 1987) However, when pyrotonolamine is used at 0.5% or less, there is a problem in that dandruff and itching prevention effects are significantly reduced.

Therefore, the present inventors have diligently researched to solve the above problems, and as a result, they contain economical, anti-dandruff and itching effects by containing a small amount of pyrotonolamine and a glycine hydrochloride-based amphoteric surfactant which is synergistic with pyrotonolamine. The present invention completes an excellent anti-dandruff shampoo composition.

Hereinafter, the present invention will be described in detail.

The present invention is 5 to 30 parts by weight of anionic and nonionic surfactants, 0.1 to 0.5 parts by weight of pyrotonolamine, 0.1 to 5.0 parts by weight of glycine-based amphoteric surfactants, conventional hair conditioners, pigments, flavors, preservatives, A shampoo composition consisting of a pH adjuster, a viscosity adjuster and water.

The surfactant used in the present invention is 5 to 30 parts by weight, preferably 10 to 25 parts by weight, each of a surfactant selected from anionic surfactants and nonionic surfactants. Anionic surfactant is represented by general formula (II).

RO (CH ₂ CH ₂ 0) n-SO ₃ M (II)

Wherein R is an alkyl group having 8 to 20 carbon atoms, n is an integer of 0 to 4, and M is a monovalent or divalent alkali metal salt selected from sodium, potassium, magnesium, triethanolamine and ammonium ions. Typical examples of the general formula (II) compound include sodium lauryl sulfate, lauryl ammonium sulfate, lauryl magnesium sulfate, lauryl sulfate triethanolamine, polyoxyethylene lauryl sulfate, polyoxyethylene lauryl ammonium sulfate and the like.

Nonionic surfactant is represented by general formula (III) or (IV).

R ₁ R ₂ R ₃ N → O (III)

In the above formula, R ₁ is an alkyl group having 8 to 20 carbon atoms, R ₂ and R ₃ are alkyl groups having 1 to ₃ carbon atoms, R ₄ CO is an alkoxy group having 8 to 20 carbon atoms, and n is 0 or 1. Representative examples thereof include lauryl dimethylamine oxide, palm oil alkyldimethylamine oxide, lauric acid diethanolamide, palm oil fatty acid diethanol amide, palm oil fatty acid monoethanolamide, and the like.

The above-mentioned surfactants can be selectively used in one kind or in mixture of two or more kinds in the shampoo composition of the present invention.

The pyrotonolamine used in the present invention is used in an amount of 0.1 to 0.5 parts by weight, preferably 0.2 to 0.4 parts by weight.

Glycine hydrochloride-type amphoteric surfactant used for this invention is represented by general formula (V).

R is a C8-20 alkyl group and n is an integer of 0-3. Representative examples of the general formula (V) compounds are alkylglycine hydrochloride, alkylaminoethylglycine hydrochloride and alkyldiaminoethylglycine hydrochloride. In this invention, 0.1-5.0 weight part of said glycine hydrochloride type amphoteric surfactants are mixed 1 type or in mixture of 2 or more types, Preferably 0.5-2.0 weight part is used. Glycine hydrochloride-based amphoteric surfactants are generally used as fungicides and have no effect as an anti-dandruff and itching agent. However, when used in combination with pyrotonolamine, the anti-dandruff and itching prevention of pyrotonolamine is prevented by the bactericidal action of the scalp microorganisms of the glycine hydrochloride-based surfactant. Significantly increase the effect.

As optional ingredients used in the present invention, preservatives, thickeners and viscosity adjusting agents, pH adjusting agents, flavorings, dyes, and hair conditioning agents which are commonly used in shampoo compositions in order to maintain basic physical properties and quality as shampoos are used.

For example, as a preservative, a mixture of methyl paraoxybenzoate, methylchloroisothiazolinone and methyl isothiazolinone (trade name: Carton CG, manufacturer: US & Haas, USA) is used, and hydroxypropyl is used as a thickener and a viscosity modifier. Methyl cellulose, hydroxy ethyl cellulose, sodium chloride, ammonium chloride, propylene glycol, hexylene glycol are used, citric acid, phosphoric acid, sodium hydroxide, potassium hydroxide, triethanolamine are used as a pH adjuster, water-soluble tar pigments are used as dyes, As the hair conditioning agent, polyquaternium-7, polyquaternium-10, polyoxyethylene lanolin, lanolin alcohol, methyl polysiloxane, dimethicone copolyol, hydrolyzed animal protein, ethylene glycol monostearic acid, and the like are used. Can be.

Hereinafter, the present invention will be described in detail with Examples and Comparative Examples.

[Examples 1-3 and Comparative Examples 1-5]

The weight parts of the ingredients in Table 1 were used, and the preparation method was an anionic surfactant and a nonionic surfactant in 45 parts by weight of water, and then warmed up to 45 ° C., followed by a hair conditioner, an antidandruffing agent and an amphoteric surfactant for 30 minutes. After stirring and dissolving, the mixture was cooled to 35 ° C., and a dye, a perfume, and a preservative were added thereto, and stirred and dissolved for 30 minutes to adjust the pH to 6.5 with a pH adjuster, followed by adding water to the weight parts shown in Table 1.

TABLE 1

* Hydrolyzed animal protein from Croda.

The anti-dandruff effect test for Examples 1 to 3 and Comparative Examples 1 to 5 are as follows, and the results are shown in Table 2.

(Anti-dandruff effect test)

A male with 22 to 36 years of age who had a relatively high dandruff was selected for 5 months for each shampoo.

Trituration with a normal shampoo before the start of the test, and after the hairdressing, the accumulated dandruff was collected on the 3rd day, and the weight of the collected dandruff and the shampoo composition shown in Table 1 were performed every 3 days, and accumulated on the 3rd day after the end of the test. The weight of dandruff was compared.

Accumulated dandruff was collected directly from the scalp with a vacuum suction device to determine the rate of dandruff reduction.

TABLE 2

As shown in Table 2, a shampoo composition in which pyrotonolamine and an alkyldiaminoethylglycine are mixed, that is, Examples 1 to 3 are shampoo compositions using peroctonolamine alone, that is, Comparative Examples 1 to 3 and alkyl hydrochloride. Compared to the shampoo composition using diaminoethylglycine alone, ie, Comparative Examples 4 to 5, the effect of preventing dandruff and itching is excellent. Therefore, it can be seen that pyroxtonolamine exhibits anti-dandruff synergy by alkyl diaminoethylglycine hydrochloride.

EXAMPLES 4-9

It is the same as Example 1 except using the weight part of the component of Table 3.

TABLE 3

*: Hydrolyzed animal protein from Croda.

The anti-dandruff effect test for Examples 4 to 9 is as follows, and the results are shown in Table 4.

Anti-dandruff effect test

A randomly selected male who had a relatively large dandruff age of 22 to 36 years was selected as the subject, and each shampoo composition was tested for 30 months with 5 persons in total for 1 month.

Trituration with a regular shampoo before the start of the test, and collected the dandruff accumulated in the 3 days after the tricycle and the weight of the dandruff collected and triturated once every 3 days with the shampoo composition shown in Table 3 The weight was compared and the results are shown in Table 4.

Here, it was determined that the dandruff reduction effect was only when the dandruff reduction rate was 30% or more, and it was determined that there was no dandruff prevention effect when the dandruff reduction rate was 30% or less.

TABLE 4

As shown in Table 4, 0.4 parts by weight of pyrotonolamine and glycerine hydrochloride-based amphoteric surfactants used by one or two or more selected by type can be seen that all have an anti-dandruff effect.

Claims (2)

0.1-0.5 parts by weight of 1-hydroxy-4-methyl-6- (2, 4, 4, -trimethylpentyl) -2 (1H) -pyridone ethanolamine salt in a general shampoo composition, in general formula (V) A shampoo composition comprising from 0.1 to 5.0 parts by weight of a glycine hydrochloride-based amphoteric surfactant.

Here, R is a C8-20 alkyl group, n is an integer of 0-3. The shampoo composition according to claim 1, wherein the glycine hydrochloride-based amphoteric surfactant is one or more selected from alkylglycine hydrochloride, alkylaminoethylglycine hydrochloride and alkyldiaminoethylglycine hydrochloride.